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  1. Protective Action of 3,5-Diiodo-L-Thyronine on Cigarette Smoke-Induced Mitochondrial Dysfunction in Human Alveolar Epithelial Cells

    Article • Biomedicines, April 2025, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  2. miRNA Signatures in Alveolar Macrophages Related to Cigarette Smoke: Assessment and Bioinformatics Analysis

    Article • International Journal of Molecular Sciences, February 2025, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  3. Cigarette Smoke Exposure and microRNA in Human Alveolar Macrophages: A Pilot Study

    Article • May 2024, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  4. MicroRNA Monitoring in Human Alveolar Macrophages from Patients with Smoking-Related Lung Diseases: A Preliminary Study

    Article • Biomedicines, May 2024, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  5. MicroRNAs Monitoring in Human Alveolar Macrophages from Patients with Smoking-Related Lung Diseases: A Preliminary Study

    Article • April 2024, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  6. Microplastics and Nanoplastics in Atheromas and Cardiovascular Events

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, March 2024, New England Journal of Medicine (NEJM/MMS)

    Prof. Ph.D Giuseppe Spaziano

  7. A Multiple Synergic Treatment for Non-Healing Ulcer Management in a Patient with Klippel–Trenaunay Syndrome

    Article • Reports — Medical Cases Images and Videos, July 2023, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  8. Association between Sex-Related ALOX5 Gene Polymorphisms and Lung Atopy Risk

    Article • Journal of Clinical Medicine, April 2023, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  9. Lung microRNAs Expression in Lung Cancer and COPD: A Preliminary Study

    Article • Biomedicines, February 2023, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  10. The Role of MMPs in the Era of CFTR Modulators: An Additional Target for Cystic Fibrosis Patients?

    Article • Biomolecules, February 2023, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  11. Oxygen–Ozone Therapy in Cervicobrachial Pain: A Real-Life Experience

    Article • Journal of Clinical Medicine, December 2022, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  12. Similar programmed death ligand 1 (PD-L1) expression profile in patients with mild COPD and lung cancer

    Article • Scientific Reports, December 2022, Springer Science + Business Media

    Prof. Ph.D Giuseppe Spaziano

  13. Design and synthesis of functionalized 4-aryl-Catechol derivatives as new antiinflammtory agents with in vivo efficacy

    Article • European Journal of Medicinal Chemistry, December 2022, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  14. Overview of Antiviral Drug Therapy for COVID-19: Where Do We Stand?

    Article • Biomedicines, November 2022, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  15. Formulation of Solid Lipid Nanoparticles Loaded with Nociceptin/Orphanin FQ (N/OFQ) and Characterization in a Murine Model of Airway Hyperresponsiveness

    Article • Pharmaceuticals, September 2022, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  16. Circulating MicroRNAs Expression Profile in Lung Inflammation: A Preliminary Study

    Article • Journal of Clinical Medicine, September 2022, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  17. Similar Programmed Death Ligand 1 (PD-L1) expression profile in patients with mild COPD and lung cancer

    Article • March 2022, Research Square

    Prof. Ph.D Giuseppe Spaziano

  18. Sphingosine‐1‐phosphate/TGF‐β axis drives epithelial mesenchymal transition in asthma‐like disease

    Article • British Journal of Pharmacology, January 2022, Wiley

    Prof. Ph.D Giuseppe Spaziano

  19. Drug–Drug Interactions in Vestibular Diseases, Clinical Problems, and Medico-Legal Implications

    Article • International Journal of Environmental Research and Public Health, December 2021, MDPI AG

    Prof. Ph.D Giuseppe Spaziano

  20. Neuron-specific enolase serum levels in COVID-19 are related to the severity of lung injury

    Article • PLOS One, May 2021, PLOS

    Prof. Ph.D Giuseppe Spaziano

  21. SNPs in asthma patients: gender difference in anti-leukotriene therapy

    Article • September 2020, European Respiratory Society (ERS)

    Prof. Ph.D Giuseppe Spaziano

  22. 5α-dihydrotestosterone abrogates sex bias in asthma like features in the mouse

    Article • Pharmacological Research, August 2020, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  23. Formulation and Characterization of Solid Lipid Nanoparticles Loading RF22-c, a Potent and Selective 5-LO Inhibitor, in a Monocrotaline-Induced Model of Pulmonary Hypertension

    Article • Frontiers in Pharmacology, February 2020, Frontiers

    Prof. Ph.D Giuseppe Spaziano

  24. Functional contribution of sphingosine‐1‐phosphate to airway pathology in cigarette smoke‐exposed mice

    Article • British Journal of Pharmacology, November 2019, Wiley

    Prof. Ph.D Giuseppe Spaziano

  25. Montelukast induces better control of symptoms and management of lung function, and decreased inflammation in women compared with men

    Article • September 2019, European Respiratory Society (ERS)

    Prof. Ph.D Giuseppe Spaziano

  26. Montelukast Improves Symptoms and Lung Function in Asthmatic Women Compared With Men

    Article • Frontiers in Pharmacology, September 2019, Frontiers

    Prof. Ph.D Giuseppe Spaziano

  27. Panitumumab Induced Forearm Panniculitis in Two Women With Metastatic Colon Cancer

    Article • Current Drug Safety, September 2019, Bentham Science Publishers

    Prof. Ph.D Giuseppe Spaziano

  28. Leukotriene-mediated sex dimorphism in murine asthma-like features during allergen sensitization

    Article • Pharmacological Research, January 2019, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  29. N/OFQ-NOP System and Airways

    Article • January 2019, Springer Science + Business Media

    Prof. Ph.D Giuseppe Spaziano

  30. Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness

    Article • Physiological Reports, October 2018, Wiley

    Prof. Ph.D Giuseppe Spaziano

  31. Relationship Between Gender and the Effectiveness of Montelukast: An Italian/Danish Register-Based Retrospective Cohort Study

    Article • Frontiers in Pharmacology, August 2018, Frontiers

    Prof. Ph.D Giuseppe Spaziano

  32. StAR protein and steroidogenic enzyme expressions in the rat Harderian gland

    Article • Comptes Rendus Biologies, March 2018, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  33. Lung Mesenchymal Stem Cells Ameliorate Elastase-Induced Damage in an Animal Model of Emphysema

    Article • Stem Cells International, January 2018, Hindawi Publishing Corporation

    Prof. Ph.D Giuseppe Spaziano, Giuseppe Spaziano

  34. Toll-Like Receptor 4 Is Essential for the Expression of Sphingosine-1-Phosphate-Dependent Asthma-Like Disease in Mice

    Article • Frontiers in Immunology, October 2017, Frontiers

    Prof. Ph.D Giuseppe Spaziano

  35. Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma

    Article • European Journal of Medicinal Chemistry, October 2017, Elsevier

    Prof. Ph.D Giuseppe Spaziano, Prof. Antoni Sureda

  36. theophylline affect human bronchial epithelial cells

    Article • Drug Design Development and Therapy, January 2017, Dove Medical Press

    Dr Luca Gallelli, Dr Mariarita Perri, dr Roberto Cannataro, Giuseppe Spaziano, Prof. Ph.D Giuseppe Spaziano

  37. Disodium cromoglycate inhibits asthma-like features induced by sphingosine-1-phosphate

    Article • Pharmacological Research, November 2016, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  38. Nociceptin reduces the inflammatory immune microenvironment in a conventional murine model of airway hyperresponsiveness

    Article • Clinical & Experimental Allergy, October 2016, Wiley

    Prof. Ph.D Giuseppe Spaziano

  39. Intratracheal Administration of Mesenchymal Stem Cells Modulates Tachykinin System, Suppresses Airway Remodeling and Reduces Airway Hyperresponsiveness in an Animal Model

    Article • PLOS One, July 2016, PLOS

    Prof. Ph.D Giuseppe Spaziano

  40. The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo

    Article • Biochemical Pharmacology, July 2016, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  41. Nociceptin/orphanin FQ (N/OFQ) modulates immunopathology and airway hyperresponsiveness representing a novel target for the treatment of asthma

    Article • British Journal of Pharmacology, March 2016, Wiley

    Prof. Ph.D Giuseppe Spaziano

  42. Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation

    Article • Pharmacological Research, January 2016, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  43. New Role of Adult Lung c-kit+ Cells in a Mouse Model of Airway Hyperresponsiveness

    Article • Mediators of Inflammation, January 2016, Hindawi Publishing Corporation

    Prof. Ph.D Giuseppe Spaziano

  44. Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation

    Article • Pharmacological Research, October 2015, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  45. Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes

    Article • European Journal of Medicinal Chemistry, April 2015, Elsevier

    Prof. Ph.D Giuseppe Spaziano

  46. Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Prof. Ph.D Giuseppe Spaziano

  47. Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide

    Article • BMC Pharmacology and Toxicology, November 2014, Springer Science + Business Media

    Professor Michele Navarra, Prof. Ph.D Giuseppe Spaziano

  48. Effects of sex hormones on bronchial reactivity during the menstrual cycle

    Article • BMC Pulmonary Medicine, July 2014, Springer Science + Business Media

    Prof. Ph.D Giuseppe Spaziano

  49. The effects of sulodexide on both clinical and molecular parameters in patients with mixed arterial and venous ulcers of lower limbs

    Article • Drug Design Development and Therapy, May 2014, Taylor & Francis

    Professor Bruno Amato, Dr Luca Gallelli, Giuseppe Spaziano, Prof. Ph.D Giuseppe Spaziano

  50. Nociceptin/orphanin FQ receptor activation decreases the airway hyperresponsiveness induced by allergen in sensitized mice

    Article • AJP Lung Cellular and Molecular Physiology, May 2013, American Physiological Society

    Prof. Ph.D Giuseppe Spaziano

  51. Skeletal Muscle Oxidative Metabolism in an Animal Model of Pulmonary Emphysema

    Article • American Journal of Respiratory Cell and Molecular Biology, February 2013, American Thoracic Society

    Prof. Ph.D Giuseppe Spaziano

  52. Plasma glutamine decreases immediately after surgery and is related to incisiveness

    Article • Journal of Cellular Physiology, January 2012, Wiley

    Prof. Ph.D Giuseppe Spaziano, Associate Professor VIncenzo Pota