All Stories

  1. The multivariate genetic architecture of psychiatric and insulin resistance multimorbidity

    Article • European Neuropsychopharmacology, October 2026, Elsevier

    Giuseppe Fanelli

  2. Shared genetic and molecular architecture between insulin resistance and cognitive performance

    Article • July 2026, openRxiv

    Giuseppe Fanelli

  3. Educational Attainment Polygenic Scores and School Performance in Adolescents With Psychiatric Disorders: A Population-Based Analysis of 86,122 Individuals From the iPSYCH2015 Case-Cohort

    Article • Journal of the American Academy of Child & Adolescent Psychiatry, July 2026, Elsevier

    Giuseppe Fanelli

  4. Personality domains in early stages of psychosis: a systematic review and meta-analysis

    Article • European Archives of Psychiatry and Clinical Neuroscience, November 2025, Springer Science + Business Media

    Giuseppe Fanelli

  5. Schizophrenia Genetics Modulates Clinical Depressive Features

    Article • American Journal of Medical Genetics Part B Neuropsychiatric Genetics, October 2025, Wiley

    Giuseppe Fanelli

  6. Polygenic predisposition to transdiagnostic symptom dimensions and treatment outcomes across psychiatric disorders

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, October 2025, Elsevier

    Giuseppe Fanelli

  7. The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts

    Article • Alzheimer s & Dementia, October 2025, Wiley

    Giuseppe Fanelli

  8. Psychiatric Risk Governance Across Jurisdictions: A Comparative Analysis of Involuntary Treatment, Community Treatment Orders, and Forensic Mental Health Services

    Article • Healthcare, September 2025, MDPI AG

    Giuseppe Fanelli

  9. Asenapine for aggressive behaviours in psychiatric disorders: a systematic review of efficacy and real-world effectiveness

    Article • International Journal of Psychiatry in Clinical Practice, September 2025, Taylor & Francis

    Giuseppe Fanelli

  10. Factors associated with drug–drug interactions involving citalopram in the UK Biobank

    Article • BJPsych Open, August 2025, Royal College of Psychiatrists

    Giuseppe Fanelli

  11. Predicted plasma proteomics from genetic scores and treatment outcomes in major depression: a meta-analysis

    Article • European Neuropsychopharmacology, July 2025, Elsevier

    Giuseppe Fanelli

  12. Insulin resistance and poorer treatment outcomes in depression: evidence from UK Biobank primary care data

    Article • The British Journal of Psychiatry, June 2025, Royal College of Psychiatrists

    Giuseppe Fanelli

  13. Correction: Mild motor signs and depression: more than just medication side effects?

    Article • European Archives of Psychiatry and Clinical Neuroscience, May 2025, Springer Science + Business Media

    Giuseppe Fanelli

  14. Mild motor signs and depression: more than just medication side effects?

    Article • European Archives of Psychiatry and Clinical Neuroscience, April 2025, Springer Science + Business Media

    Giuseppe Fanelli

  15. Local patterns of genetic sharing between neuropsychiatric and insulin resistance-related conditions

    Article • Translational Psychiatry, April 2025, Springer Science + Business Media

    Giuseppe Fanelli, Fernando Fernandez-Aranda

  16. Specific symptomatology profile associated with treatment resistant depression: A multicentric study from the Group for the Study of Resistant Depression with a focus on sex

    Article • Journal of Affective Disorders, April 2025, Elsevier

    Giuseppe Fanelli, Antonino Messina

  17. Oropharyngeal microbiota in patients with psychotic disorders: A scoping review on compositional and functional alterations

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, March 2025, Elsevier

    Giuseppe Fanelli

  18. Predictive coding in neuropsychiatric disorders: A systematic transdiagnostic review

    Article • Neuroscience & Biobehavioral Reviews, February 2025, Elsevier

    Giuseppe Fanelli

  19. The interface of depression and diabetes: treatment considerations

    Article • Translational Psychiatry, January 2025, Springer Science + Business Media

    Giuseppe Fanelli

  20. Shared genetics and causal relationship between sociability and the brain’s default mode network

    Article • Psychological Medicine, January 2025, Cambridge University Press

    Giuseppe Fanelli

  21. Polygenic scores and antidepressant treatment outcomes in major depression: a critical integrative review

    Article • Neuroscience Applied, January 2025, Elsevier

    Giuseppe Fanelli

  22. The gut microbiota's role in bulimia nervosa and binge eating disorder: etiological insights and therapeutic implications from a scoping review

    Article • Neuroscience Applied, January 2025, Elsevier

    Giuseppe Fanelli

  23. Differences in emotion recognition between nonimmersive versus immersive virtual reality: preliminary findings in schizophrenia and bipolar disorder

    Article • International Clinical Psychopharmacology, December 2024, Wolters Kluwer Health

    Giuseppe Fanelli

  24. The revival of psilocybin between scientific excitement, evidence of efficacy, and real-world challenges

    Article • CNS Spectrums, December 2024, Cambridge University Press

    Giuseppe Fanelli

  25. Anhedonia is associated with a specific depression profile and poor antidepressant response

    Article • The International Journal of Neuropsychopharmacology, November 2024, Oxford University Press (OUP)

    Giuseppe Fanelli, Antonino Messina

  26. Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases

    Article • Alzheimer s Research & Therapy, October 2024, Springer Science + Business Media

    Giuseppe Fanelli

  27. Unravelling the joint genetic architecture between psychiatic and insulin-related traits in the general population

    Article • October 2024, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  28. The multivariate genetic architecture of psychiatric and insulin resistance multimorbidity

    Article • October 2024, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  29. Genetic factors and symptom dimensions associated with antidepressant treatment outcomes: clues for new potential therapeutic targets?

    Article • European Archives of Psychiatry and Clinical Neuroscience, August 2024, Springer Science + Business Media

    Giuseppe Fanelli

  30. The clinical perspective on late-onset depression in European real-world treatment settings

    Article • European Neuropsychopharmacology, July 2024, Elsevier

    Giuseppe Fanelli

  31. Mirtazapine blood levels and antidepressant response

    Article • International Journal of Psychiatry in Clinical Practice, June 2024, Taylor & Francis

    Giuseppe Fanelli

  32. Shared familial risk for type 2 diabetes mellitus and psychiatric disorders: a nationwide multigenerational genetics study

    Article • Psychological Medicine, May 2024, Cambridge University Press

    Giuseppe Fanelli, Fernando Fernandez-Aranda

  33. Shared genetics linking sociability with the brain's default mode network.

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  34. The association of glucose metabolism measures and diabetes status with Alzheimer’s disease biomarkers of amyloid and tau: A systematic review and meta-analysis

    Article • Neuroscience & Biobehavioral Reviews, April 2024, Elsevier

    Giuseppe Fanelli, Fernando Fernandez-Aranda

  35. Local patterns of genetic sharing challenge the boundaries between neuropsychiatric and insulin resistance-related conditions

    Article • March 2024, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli, Fernando Fernandez-Aranda

  36. Pharmacological treatments for psychotic depression: a systematic review and network meta-analysis

    Article • The Lancet Psychiatry, March 2024, Elsevier

    Giuseppe Fanelli

  37. The bidirectional interaction between antidepressants and the gut microbiota: are there implications for treatment response?

    Article • International Clinical Psychopharmacology, February 2024, Wolters Kluwer Health

    Giuseppe Fanelli

  38. Polygenic scores of subcortical brain volumes as possible modulators of treatment response in depression

    Article • Neuroscience Applied, January 2024, Elsevier

    Giuseppe Fanelli

  39. Genetic relationship between the immune system and autism

    Article • Brain Behavior & Immunity - Health, December 2023, Elsevier

    Giuseppe Fanelli

  40. Genetic relationship between the immune system and autism spectrum disorder and traits

    Article • October 2023, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  41. 33. SHARED GENETICS LINKING SOCIABILITY WITH THE BRAIN'S DEFAULT MODE NETWORK

    Article • European Neuropsychopharmacology, October 2023, Elsevier

    Giuseppe Fanelli

  42. T13. EPIGENETIC FACTORS INFLUENCING CO-MORBIDITY OF INSULIN-RELATED SOMATIC AND BRAIN DISORDERS

    Article • European Neuropsychopharmacology, October 2023, Elsevier

    Giuseppe Fanelli

  43. W12. LOOKING BEYOND LABELS: DEFINING DIMENSIONAL PSYCHIATRIC SYMPTOM CLUSTERS WITH INSULIN-RELATED SOMATIC MEASURES BASED ON LARGE POPULATION-BASED GENETIC DATASETS

    Article • European Neuropsychopharmacology, October 2023, Elsevier

    Giuseppe Fanelli

  44. W16. THE MULTIVARIATE GENETIC ARCHITECTURE OF PSYCHIATRIC AND SOMATIC INSULIN RESISTANCE-RELATED MULTIMORBIDITY

    Article • European Neuropsychopharmacology, October 2023, Elsevier

    Giuseppe Fanelli

  45. Correlation between emotion dysregulation and mood symptoms of bipolar disorder: A systematic review and meta‐analysis

    Article • Acta Psychiatrica Scandinavica, September 2023, Wiley

    Giuseppe Fanelli

  46. Clinical insights into the cross-link between mood disorders and type 2 diabetes: A review of longitudinal studies and Mendelian randomisation analyses

    Article • Neuroscience & Biobehavioral Reviews, September 2023, Elsevier

    Giuseppe Fanelli

  47. Polygenic scores of subcortical brain volumes as possible modulators of treatment response in depression

    Article • August 2023, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  48. Body mass index and clinical outcomes in individuals with major depressive disorder: Findings from the GSRD European Multicenter Database

    Article • Journal of Affective Disorders, August 2023, Elsevier

    Giuseppe Fanelli

  49. Real-world characteristics of European patients receiving SNRIs as first-line treatment for major depressive disorder

    Article • Journal of Affective Disorders, July 2023, Elsevier

    Giuseppe Fanelli

  50. Clinical specificity profile for novel rapid acting antidepressant drugs

    Article • International Clinical Psychopharmacology, June 2023, Wolters Kluwer Health

    Giuseppe Fanelli

  51. Age or age of onset: which is the best criterion to classify late-life depression?

    Article • International Clinical Psychopharmacology, March 2023, Wolters Kluwer Health

    Giuseppe Fanelli

  52. Clinical correlates and prognostic implications of severe suicidal ideation in major depressive disorder

    Article • International Clinical Psychopharmacology, February 2023, Wolters Kluwer Health

    Giuseppe Fanelli

  53. Hyperthyroidism and depression: a clinical case of atypical thyrotoxicosis manifestation

    Article • International Clinical Psychopharmacology, February 2023, Wolters Kluwer Health

    Giuseppe Fanelli

  54. Melancholic features and typical neurovegetative symptoms of major depressive disorder show specific polygenic patterns

    Article • Journal of Affective Disorders, January 2023, Elsevier

    Giuseppe Fanelli

  55. Association between polygenic risk scores of subcortical brain volumes and antidepressant response: a meta-analysis

    Article • Neuroscience Applied, January 2023, Elsevier

    Giuseppe Fanelli

  56. Emotional side effects of antidepressants: a systematic review

    Article • Neuroscience Applied, January 2023, Elsevier

    Giuseppe Fanelli

  57. Epigenetic factors influencing the multimorbidity between somatic and brain-insulinopathies

    Article • Neuroscience Applied, January 2023, Elsevier

    Giuseppe Fanelli

  58. Pharmacological treatment of psychotic depression: a systematic review and network meta-analysis

    Article • Neuroscience Applied, January 2023, Elsevier

    Giuseppe Fanelli

  59. What emotional regulation strategies are most related to the affective symptoms of bipolar disorder? A systematic review and network meta-analysis

    Article • Neuroscience Applied, January 2023, Elsevier

    Giuseppe Fanelli

  60. The link between cognition and somatic conditions related to insulin resistance in the UK Biobank study cohort: a systematic review

    Article • Neuroscience & Biobehavioral Reviews, December 2022, Elsevier

    Fernando Fernandez-Aranda, Giuseppe Fanelli

  61. LOCAL PATTERNS OF SHARED GENETICS AND A GENETIC LATENT FACTOR OF INSULIN RESISTANCE AND NEUROPSYCHIATRIC MULTIMORBIDITY

    Article • European Neuropsychopharmacology, October 2022, Elsevier

    Giuseppe Fanelli

  62. PSYCHIATRIC AND INSULIN-RELATED SOMATIC MULTIMORBIDITY: INSIGHTS INTO UNDERLYING GENETIC ARCHITECTURE AND BRAIN STRUCTURES INVOLVED

    Article • European Neuropsychopharmacology, October 2022, Elsevier

    Giuseppe Fanelli

  63. T75. NO LABELS NEEDED: UNDERSTANDING PSYCHIATRIC DISORDERS BASED ON GENETIC TRAITS

    Article • European Neuropsychopharmacology, October 2022, Elsevier

    Giuseppe Fanelli

  64. Patterns of antipsychotic prescription and accelerometer-based physical activity levels in people with schizophrenia spectrum disorders: a multicenter, prospective study

    Article • International Clinical Psychopharmacology, September 2022, Wolters Kluwer Health

    Giuseppe Fanelli

  65. Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders

    Article • Yearbook of Paediatric Endocrinology, September 2022, Bioscientifica

    Giuseppe Fanelli

  66. The sociodemographic and clinical phenotype of European patients with major depressive disorder undergoing first-line antidepressant treatment with NaSSAs

    Article • Journal of Affective Disorders, September 2022, Elsevier

    Giuseppe Fanelli

  67. Temporally ordered associations between type 2 diabetes and brain disorders – a Danish register-based cohort study

    Article • BMC Psychiatry, August 2022, Springer Science + Business Media

    Fernando Fernandez-Aranda, Giuseppe Fanelli

  68. The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controls

    Article • Comprehensive Psychiatry, August 2022, Elsevier

    Giuseppe Fanelli

  69. Epigenetics and aetiology of mental illness

    Article • August 2022, Oxford University Press (OUP)

    Giuseppe Fanelli

  70. Clinical correlates and prognostic impact of binge-eating symptoms in major depressive disorder

    Article • International Clinical Psychopharmacology, July 2022, Wolters Kluwer Health

    Giuseppe Fanelli

  71. The dilemma of polypharmacy in psychosis: is it worth combining partial and full dopamine modulation?

    Article • International Clinical Psychopharmacology, July 2022, Wolters Kluwer Health

    Giuseppe Fanelli

  72. Machine Learning Prediction of Comorbid Substance Use Disorders among People with Bipolar Disorder

    Article • Journal of Clinical Medicine, July 2022, MDPI AG

    Giuseppe Fanelli

  73. Depression, antidepressants, and insulin resistance: which link?

    Article • European Neuropsychopharmacology, July 2022, Elsevier

    Giuseppe Fanelli

  74. The U-shaped relationship between parental age and the risk of bipolar disorder in the offspring: A systematic review and meta-analysis

    Article • European Neuropsychopharmacology, July 2022, Elsevier

    Giuseppe Fanelli

  75. Epigenetic Basis of Psychiatric Disorders: A Narrative Review

    Article • CNS & Neurological Disorders - Drug Targets, May 2022, Bentham Science Publishers

    Giuseppe Fanelli

  76. Evidence on sociodemographic and clinical correlates of antidepressant combination or augmentation with second-generation antipsychotics in major depressive disorder

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, March 2022, Elsevier

    Giuseppe Fanelli

  77. Polygenic risk scores for neuropsychiatric, inflammatory, and cardio‐metabolic traits highlight possible genetic overlap with suicide attempt and treatment‐emergent suicidal ideation

    Article • American Journal of Medical Genetics Part B Neuropsychiatric Genetics, February 2022, Wiley

    Giuseppe Fanelli

  78. Obsessive-compulsive symptoms in major depressive disorder correlate with clinical severity and mixed features

    Article • International Clinical Psychopharmacology, February 2022, Wolters Kluwer Health

    Giuseppe Fanelli

  79. Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders

    Article • Translational Psychiatry, February 2022, Springer Science + Business Media

    Giuseppe Fanelli

  80. A meta-analysis of polygenic risk scores for mood disorders, neuroticism, and schizophrenia in antidepressant response

    Article • European Neuropsychopharmacology, February 2022, Elsevier

    Giuseppe Fanelli

  81. The sociodemographic and clinical profile of patients with major depressive disorder receiving SSRIs as first-line antidepressant treatment in European countries

    Article • European Archives of Psychiatry and Clinical Neuroscience, January 2022, Springer Science + Business Media

    Giuseppe Fanelli

  82. Bipolar disorder and comorbid substance use disorder: a machine-learning approach

    Article • Neuroscience Applied, January 2022, Elsevier

    Giuseppe Fanelli

  83. Genetic dissection of the clinical heterogeneity of major depressive disorder

    Article • Neuroscience Applied, January 2022, Elsevier

    Giuseppe Fanelli

  84. Hyperthyroidism and depression: a clinical case of atypical thyrotoxicosis manifestation

    Article • Neuroscience Applied, January 2022, Elsevier

    Giuseppe Fanelli

  85. Hyperthyroidism and depression: focusing on this complex interplay

    Article • Neuroscience Applied, January 2022, Elsevier

    Giuseppe Fanelli

  86. The Italian Version of the Brief Assessment of Cognition in Affective Disorders: Performance of Patients with Bipolar Disorder and Healthy Controls

    Article • SSRN Electronic Journal, January 2022, Elsevier

    Giuseppe Fanelli

  87. The U-shaped relationship between parental age and the risk of bipolar disorder in the offspring – A systematic review and meta-analysis

    Article • Neuroscience Applied, January 2022, Elsevier

    Giuseppe Fanelli

  88. The cross-link between major depressive disorder and type 2 diabetes mellitus: a review of longitudinal and mendelian randomisation studies

    Article • Neuroscience Applied, January 2022, Elsevier

    Giuseppe Fanelli

  89. Social withdrawal as a trans-diagnostic predictor of short-term remission: a meta-analysis of five clinical cohorts

    Article • International Clinical Psychopharmacology, December 2021, Wolters Kluwer Health

    Giuseppe Fanelli

  90. P.0882 A meta-analysis of polygenic risk scores for mood disorders, neuroticism, and schizophrenia in antidepressant response

    Article • European Neuropsychopharmacology, December 2021, Elsevier

    Giuseppe Fanelli

  91. W68. A META-ANALYSIS OF POLYGENIC RISK SCORES FOR MOOD DISORDERS, NEUROTICISM, AND SCHIZOPHRENIA IN ANTIDEPRESSANT RESPONSE

    Article • European Neuropsychopharmacology, October 2021, Elsevier

    Giuseppe Fanelli

  92. TH59. INSULINOPATHIES OF THE BRAIN? GENETIC OVERLAP BETWEEN SOMATIC INSULIN-RELATED AND NEUROPSYCHIATRIC DISORDERS

    Article • European Neuropsychopharmacology, October 2021, Elsevier

    Giuseppe Fanelli

  93. Gastrointestinal side effects associated with antidepressant treatments in patients with major depressive disorder: A systematic review and meta-analysis

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, July 2021, Elsevier

    Giuseppe Fanelli

  94. A meta-analysis of polygenic risk scores for mood disorders, neuroticism, and schizophrenia in antidepressant response

    Article • June 2021, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  95. Higher polygenic risk scores for schizophrenia may be suggestive of treatment non-response in major depressive disorder

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, June 2021, Elsevier

    Giuseppe Fanelli

  96. Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  97. Polygenic risk scores for psychiatric, inflammatory, and cardio-metabolic traits and diseases highlight possible genetic overlaps with suicide attempt and treatment-emergent suicidal ideation

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  98. P.169 Genetic overlap between somatic insulin-related and neuro-psychiatric disorders

    Article • European Neuropsychopharmacology, November 2020, Elsevier

    Giuseppe Fanelli

  99. P.171 Higher polygenic risk scores for schizophrenia may be suggestive of treatment non-response in major depressive disorder

    Article • European Neuropsychopharmacology, November 2020, Elsevier

    Giuseppe Fanelli

  100. P.179 Polygenic risk scores for multiple psychiatric, inflammatory and cardio-metabolic traits highlight possible genetic overlap with suicide attempt

    Article • European Neuropsychopharmacology, November 2020, Elsevier

    Giuseppe Fanelli

  101. Higher polygenic risk scores for schizophrenia may be suggestive of treatment non-response in major depressive disorder

    Article • January 2020, Cold Spring Harbor Laboratory Press

    Giuseppe Fanelli

  102. Reduced plasma Fetuin-A is a promising biomarker of depression in the elderly

    Article • European Archives of Psychiatry and Clinical Neuroscience, December 2019, Springer Science + Business Media

    Giuseppe Fanelli

  103. P.306 Reduced chemokine ligand 1/GRO chemokine plasma levels are a possible biomarker of elderly depression

    Article • European Neuropsychopharmacology, December 2019, Elsevier

    Giuseppe Fanelli

  104. M74 HIGHER POLYGENIC RISK SCORES FOR SCHIZOPHRENIA MAY BE SUGGESTIVE OF NON-RESPONSE TO DRUGS FOR DEPRESSION IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER

    Article • European Neuropsychopharmacology, October 2019, Elsevier

    Giuseppe Fanelli

  105. Reduced CXCL1/GRO chemokine plasma levels are a possible biomarker of elderly depression

    Article • Journal of Affective Disorders, April 2019, Elsevier

    Giuseppe Fanelli

  106. P.4.01 C-X-C chemokine signalling is implicated in major depressive disorder in a sample of Korean elderly subjects

    Article • European Neuropsychopharmacology, January 2019, Elsevier

    Giuseppe Fanelli

  107. SA92THE INFLUENCE OF THE SEROTONIN TRANSPORTER GENE 5-HTTLPR POLYMORPHISM ON SUICIDAL BEHAVIORS: A META-ANALYSIS

    Article • European Neuropsychopharmacology, January 2019, Elsevier

    Giuseppe Fanelli

  108. The influence of the serotonin transporter gene 5-HTTLPR polymorphism on suicidal behavior: a meta-analysis

    Article • European Neuropsychopharmacology, January 2019, Elsevier

    Giuseppe Fanelli

  109. The influence of the serotonin transporter gene 5-HTTLPR polymorphism on suicidal behaviors: a meta-analysis

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, January 2019, Elsevier

    Giuseppe Fanelli

  110. A Polygenic Risk Score of glutamatergic SNPs associated with schizophrenia predicts attentional behavior and related brain activity in healthy humans

    Article • European Neuropsychopharmacology, September 2017, Elsevier

    Giuseppe Fanelli