All Stories

  1. Hyaluronan Fragmentation During Inflammatory Pathologies: A Signal that Empowers Tissue Damage
  2. Hyaluronan in experimental injured/inflamed cartilage: In vivo studies
  3. Beta-arrestin 1 is involved in the catabolic response stimulated by hyaluronan degradation in mouse chondrocytes
  4. Inhibition of small HA fragment activity and stimulation of A2A adenosine receptor pathway limit apoptosis and reduce cartilage damage in experimental arthritis
  5. Inhibition of the hyaluronan oligosaccharides inflammatory response: reduction of adenosine 2A receptor activation by EPAC and PKA
  6. Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide
  7. MiRNome expression is deregulated in the peripheral lymphoid compartment of multiple myeloma
  8. The SOD mimic MnTM-2-PyP(5+) reduces hyaluronan degradation-induced inflammation in mouse articular chondrocytes stimulated with Fe (II) plus ascorbate
  9. 4-Mer Hyaluronan Oligosaccharides Stimulate Inflammation Response in Synovial Fibroblasts in Part via TAK-1 and in Part via p38-MAPK
  10. Combined treatment with hyaluronan inhibitor Pep-1 and a selective adenosine A2 receptor agonist reduces inflammation in experimental arthritis
  11. Protein kinase a mediated anti-inflammatory effects exerted by adenosine treatment in mouse chondrocytes stimulated with IL-1β
  12. The stimulation of adenosine 2A receptor reduces inflammatory response in mouse articular chondrocytes treated with hyaluronan oligosaccharides
  13. Adenosine A2A receptor activation and hyaluronan fragment inhibition reduce inflammation in mouse articular chondrocytes stimulated with interleukin-1β
  14. The inhibition of hyaluronan degradation reduced pro-inflammatory cytokines in mouse synovial fibroblasts subjected to collagen-induced arthritis
  15. Hyaluronan in part mediates IL-1beta-induced inflammation in mouse chondrocytes by up-regulating CD44 receptors
  16. Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis
  17. 6-Mer hyaluronan oligosaccharides increase IL-18 and IL-33 production in mouse synovial fibroblasts subjected to collagen-induced arthritis
  18. How Hyaluronan Could Reduce Inflammation During Arthritis? What\'s New?
  19. Hyaluronan differently modulates TLR-4 and the inflammatory response in mouse chondrocytes
  20. Polydeoxyribonucleotide reduces cytokine production and the severity of collagen-induced arthritis by stimulation of adenosine A2A receptor
  21. Hyaluronan reduces inflammation in experimental arthritis by modulating TLR-2 and TLR-4 cartilage expression
  22. Systemic administration of high-molecular weight hyaluronan stimulates wound healing in genetically diabetic mice
  23. High-molecular weight hyaluronan reduced renal PKC activation in genetically diabetic mice
  24. Small hyaluronan oligosaccharides induce inflammation by engaging both toll-like-4 and CD44 receptors in human chondrocytes
  25. Molecular Cloning and Characterization of AdultSparus aurataHemoglobin Genes
  26. Molecular size hyaluronan differently modulates toll-like receptor-4 in LPS-induced inflammation in mouse chondrocytes
  27. Glycosaminoglycans reduced inflammatory response by modulating toll-like receptor-4 in LPS-stimulated chondrocytes
  28. Differential effect of molecular size HA in mouse chondrocytes stimulated with PMA
  29. Differential effect of molecular mass hyaluronan on lipopolysaccharide-induced damage in chondrocytes
  30. Glycosaminoglycans modulate inflammation and apoptosis in LPS-treated chondrocytes
  31. Chondroitin-4-sulphate inhibits NF-kB translocation and caspase activation in collagen-induced arthritis in mice
  32. The antioxidant activity of chondroitin-4-sulphate, in carbon tetrachloride-induced acute hepatitis in mice, involves NF-κB and caspase activation
  33. Hemoglobin system of Sparus aurata: changes in fishes farmed under extreme conditions
  34. Purified human plasma glycosaminoglycans reduced NF-κB activation, pro-inflammatory cytokine production and apoptosis in LPS-treated chondrocytes
  35. Chondroitin-4-Sulphate Reduced Oxidative Injury in Caerulein-Induced Pancreatitis in Mice: The Involvement of NF-κB Translocation and Apoptosis Activation
  36. The antioxidant effect exerted by TGF-1β-stimulated hyaluronan production reduced NF-kB activation and apoptosis in human fibroblasts exposed to FeSo4 plus ascorbate
  37. Identification and gene expression of versican during early development of Xenopus
  38. NF-kB and caspases are involved in the hyaluronan and chondroitin-4-sulphate-exerted antioxidant effect in fibroblast cultures exposed to oxidative stress
  39. Transient Increase with Strenuous Exercise of Plasma Levels of Glycosaminoglycans in Humans and Horses
  40. Differential effect of growth factors on hyaluronan synthase gene expression in fibroblasts exposed to oxidative stress
  41. Chondroitin Sulphate: Antioxidant Properties and Beneficial Effects
  42. Lymphocytes from patients with early stage of B-cell chronic lymphocytic leukaemia and long survival synthesize decorin
  43. TNF-α, IFN-γ, and IL−1β modulate hyaluronan synthase expression in human skin fibroblasts: Synergistic effect by concomital treatment with FeSO4 plus ascorbate
  44. Management of lameness causes in sport horses
  45. Antioxidant Activity of Chondroitin Sulfate
  46. Purified human chondroitin-4-sulfate reduced MMP/TIMP imbalance induced by iron plus ascorbate in human fibroblast cultures
  47. Extracellular superoxide dismutase (EC-SOD) gene mutations screening in a sample of Mediterranean population
  48. Purified human plasma glycosaminoglycans limit oxidative injury induced by iron plus ascorbate in skin fibroblast cultures
  49. Oxidative stress in myotonic dystrophy type 1
  50. The antioxidant and antifibrogenic effects of the glycosaminoglycans hyaluronic acid and chondroitin-4-sulphate in a subchronic rat model of carbon tetrachloride-induced liver fibrogenesis
  51. Reduction of DNA Fragmentation and Hydroxyl Radical Production by Hyaluronic Acid and Chondroitin-4-sulphate in Iron Plus Ascorbate-induced Oxidative Stress in Fibroblast Cultures
  52. A protective effect of the synthetic coumarine derivative Cloricromene against DNB-colitis in the rat
  53. Effects of AT1 Receptor Antagonist Losartan on sICAM-1 and TNF-a Levels in Uncomplicated Hypertensive Patients
  54. Identification of paraoxonase 3 gene (PON3) missense mutations in a population of southern Italy
  55. Levetiracetam protects against kainic acid-induced toxicity
  56. Hyaluronic acid and chondroitin-4-sulphate treatment reduces damage in carbon tetrachloride-induced acute rat liver injury
  57. Glycosaminoglycans reduce oxidative damage induced by copper (Cu+2), iron (Fe+2) and hydrogen peroxide (H2O2) in human fibroblast cultures
  58. Aromatic Trap Analysis of Free Radicals Production in Experimental Collagen-induced Arthritis in the Rat: Protective Effect of Glycosaminoglycans Treatment
  59. Characterization of Serum ‘Glycosaminoglycan (GAG) Chains’ and ‘Native Proteoglycan’ Fractions in the Ostrich
  60. Lipid Peroxidation Inhibition Reduces NF-κB Activation and Attenuates Cerulein-induced Pancreatitis
  61. The effect of the phytoestrogen genistein on plasma nitric oxide concentrations, endothelin-1 levels and endothelium dependent vasodilation in postmenopausal women
  62. Improved high-performance liquid chromatographic method to estimate aminosugars and its application to glycosaminoglycan determination in plasma and serum
  63. Oxidative stress causes nuclear factor-κB activation in acute hypovolemic hemorrhagic shock
  64. Raxofelast, a hydrophilic vitamin E-like antioxidant, stimulates wound healing in genetically diabetic mice
  65. Effects of simvastatin treatment on sICAM-1 and sE-selectin levels in hypercholesterolemic subjects
  66. IRFI 042, a novel dual vitamin E-like antioxidant, inhibits activation of nuclear factor-κB and reduces the inflammatory response in myocardial ischemia–reperfusion injury
  67. Genistein supplementation and estrogen replacement therapy improve endothelial dysfunction induced by ovariectomy in rats
  68. Adrenocorticotropin reverses vascular dysfunction and protects against splanchnic artery occlusion shock
  69. Effects of Hypericum perforatum on Levels of 5-Hydroxytryptamine, Noradrenaline and Dopamine in the Cortex, Diencephalon and Brainstem of the Rat
  70. Recombinant human erythropoietin inhibits iNOS activity and reverts vascular dysfunction in splanchnic artery occlusion shock
  71. Tacrolimus suppresses tumour necrosis factor-α and protects against splanchnic artery occlusion shock
  72. The lazaroid, U-74389G, inhibits inducible nitric oxide synthase activity, reverses vascular failure and protects against endotoxin shock
  73. Cyclosporin-A reduces leukocyte accumulation and protects against myocardial ischaemia reperfusion injury in rats
  74. Sulfatide reduces leucocyte accumulation and reverts vascular failure in splanchnic artery occlusion shock
  75. Determination of clozapine, desmethylclozapine and clozapine N-oxide in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection
  76. Beneficial Effect of Raxofelast, an Hydrophilic Vitamin E Analogue, in the Rat Heart After Ischemia and Reperfusion Injury
  77. Inhibition of tumour necrosis factor and reversal of endotoxin-induced shock by U-83836E, a ‘second generation’ lazaroid in rats
  78. 17β-oestradiol reduces cardiac leukocyte accumulation in myocardial ischaemia reperfusion injury in rat
  79. The involvement of tumour necrosis factor-αin the protective effects of 17βoestradiol in splanchnic ischaemia-reperfusion injury
  80. Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: a prospective study
  81. The effects of recombinant human granulocyte-colony stimulating factor on vascular dysfunction and splanchnic ischaemia-reperfusion injury
  82. Leukocyte integrin very late antigen-4/vascular cell adhesion molecule-1 adhesion pathway in splanchnic artery occlusion shock
  83. ENDOTOXIN TOLERANCE IMPAIRS A PERTUSSIS-TOXIN-SENSITIVE G-PROTEIN REGULATING TUMOUR NECROSIS FACTOR RELEASE BY MACROPHAGES FROM TUMOUR-BEARING RATS
  84. Phenobarbital Induces the 2-Hydroxylation of Desipramine
  85. G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, inhibits tumor necrosis factor-α biosynthesis
  86. Effects of gallopamil on epinephrine and norepinephrine plasmatic levels and on txb2 and beta-tg release in patients with coronary artery disease during adrenergic stimulus with cold pressor test
  87. Tumour necrosis factor mediates e-selectin production and leukocyte accumulation in myocardial ischaemia-reperfusion injury
  88. Multiple actions of the coumarine derivative cloricromene and its protective effects on ischemic brain injury
  89. The effect of carbamazepine on the 2-hydroxylation of desipramine
  90. E-selectin involvement in the pathogenesis of splanchnic artery occlusion shock
  91. Soluble E-Selectin Levels in Acute Human Myocardial Infarction
  92. Antibodies against intercellular adhesion molecule 1 protect against myocardial ischaemia-reperfusion injury in rat
  93. TCV-309, a novel platelet activating factor antagonist, inhibits leukocyte accumulation and protects against splanchnic artery occlusion shock
  94. CYP2D6-related oxidation polymorphism in Italy
  95. Central serotoninergic system involvement in the anorexia induced by NG-nitro-L-arginine, an inhibitor of nitric oxide synthase
  96. Reduction of myocardial infarct size in rat by IRFI-048, a selective analogue of vitamin E
  97. Beneficial Effects of BAY u3405, a Novel Thromboxane A<sub>2</sub> Receptor Antagonist, in Splanchnic Artery Occlusion Shock
  98. E-selectin in the pathogenesis of experimental myocardial ischemia-reperfusion injury
  99. Food deprivation increases brain nitric oxide synthase and depresses brain serotonin levels in rats
  100. Protective Effects of IRFI-016, a New Antioxidant Agent, in Myocardial Damage, following Coronary Artery Occlusion and Reperfusion in the Rat
  101. Reduction of myocardial leukocyte accumulation and myocardial infarct size following administration of BAY u3405, a thromboxane A2 receptor antagonist, in myocardial ischaemia-reperfusion injury
  102. Tumor necrosis factor involvement in myocardial ischaemia-reperfusion injury
  103. Anorectic activity of NG-nitro-L-arginine, an inhibitor of brain nitric oxide synthase, in obese Zucker rats
  104. G 619, a Dual Thromboxane Synthase Inhibitor and Thromboxane A<sub>2</sub> Receptor Antagonist, Reduces Myocardial Damage and Polymorpho-nuclear Leukocyte Accumulation following Coronary Artery Occlusion and Reperfusion in Rats
  105. The effect of cloricromene, a coumarine derivative, on leukocyte accumulation, myocardial necrosis and TNF-α production in myocardial ischaemia-reperfusion injury
  106. Platelet activating factor interaction with tumor necrosis factor and myocardial depressant factor in splanchnic artery occlusion shock
  107. Effects of G 619 on cerebral ischemia/reperfusion injury in mongolian gerbils
  108. IRFI-016, a selective analogue of vitamin E, exerts beneficial effects on cerebral ischemmia/reperfusion injury in Mongolian gerbils
  109. Protective effects of endotoxin tolerance in tumor bearing rats
  110. Evidence that nitric oxide modulates drinking behaviour
  111. Cloricromene, a coumarine derivative, protects against lethal endotoxin shock in rats
  112. Debrisoquine oxidation in an Italian population: A study in healthy subjects and in schizophrenic patients
  113. Changes in urine volume and urinary electrolyte excretion after intracerebroventricular injection of arecoline and hemicholinium-3
  114. Platelet activating factor involvement in splanchnic artery occlusion shock in rats
  115. Effects of fructose 1,6-diphosphate on splanchnic artery occlusion shock in the rat
  116. Effects of fructose-1,6-diphosphate (FDP) in splanchnic artery occlusion (SAO) shock in the rat