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  1. Evaluation of lemon-derived extracellular nanovesicles as a nanocarrier for Clemastine: insights from intracellular calcium dynamics in an oligodendrocyte cell model

    Article • Journal of Drug Delivery Science and Technology, February 2026, Elsevier

    Professor Giovanna Rassu

  2. Intranasal Delivery of Dimethyl fumarate and Monomethyl fumarate Using Hyaluronic Acid-Based Hybrid Nanoparticles to Enhance CNS Bioavailability

    Article • Journal of Drug Delivery Science and Technology, October 2025, Elsevier

    Professor Giovanna Rassu

  3. Nasal Emulgel’s Role in Preventing Coronavirus Infection

    Article • Pharmaceutics, June 2025, MDPI AG

    Professor Giovanna Rassu

  4. Rose Bengal–Chitosan Nanocomposites for Oral Administration

    Article • Nanomaterials, May 2025, MDPI AG

    Professor Giovanna Rassu

  5. Silibinin-Loaded Amphiphilic PLGA–Poloxamer Nanoparticles: Physicochemical Characterization, Release Kinetics, and Bioactivity Evaluation in Lung Cancer Cells

    Article • Materials, November 2024, MDPI AG

    Professor Giovanna Rassu

  6. A thermosensitive chitosan hydrogel: An attempt for the nasal delivery of dimethyl fumarate

    Article • International Journal of Biological Macromolecules, October 2024, Elsevier

    Professor Giovanna Rassu

  7. Evaluating the efficacy of Rose Bengal-PVA combinations within PCL/PLA implants for sustained cancer treatment

    Article • Drug Delivery and Translational Research, September 2024, Springer Science + Business Media

    Professor Giovanna Rassu

  8. Plant-derived extracellular vesicles: a synergetic combination of a drug delivery system and a source of natural bioactive compounds

    Article • Drug Delivery and Translational Research, August 2024, Springer Science + Business Media

    Professor Giovanna Rassu

  9. Hyaluronic Acid-Based Nanoparticles Loaded with Rutin as Vasculo-Protective Tools against Anthracycline-Induced Endothelial Damages

    Article • Pharmaceutics, July 2024, MDPI AG

    Professor Giovanna Rassu

  10. A water-soluble preparation for intravenous administration of isorhamnetin and its pharmacokinetics in rats

    Article • Chemico-Biological Interactions, June 2024, Elsevier

    Professor Giovanna Rassu

  11. Design and development of a chitosan-based nasal powder of dimethyl fumarate-cyclodextrin binary systems aimed at nose-to-brain administration. A stability study

    Article • International Journal of Pharmaceutics, May 2024, Elsevier

    Professor Giovanna Rassu

  12. Improved pharmacokinetic and lymphatic uptake of Rose Bengal after transfersome intradermal deposition using hollow microneedles

    Article • Journal of Controlled Release, May 2024, Elsevier

    Professor Giovanna Rassu

  13. Corrigendum to “A technological comparison of freeze-dried poly-ɛ-caprolactone (PCL) and poly (lactic-co-glycolic acid) (PLGA) nanoparticles loaded with clozapine for nose-to-brain delivery” [J. Drug Deliv. Sci. Technol. 93 (March 2024), 105419]

    Article • Journal of Drug Delivery Science and Technology, April 2024, Elsevier

    Professor Giovanna Rassu

  14. A technological comparison of freeze-dried poly-ɛ-caprolactone (PCL) and poly (lactic-co-glycolic acid) (PLGA) nanoparticles loaded with clozapine for nose-to-brain delivery

    Article • Journal of Drug Delivery Science and Technology, March 2024, Elsevier

    Professor Giovanna Rassu

  15. Delivering hydrosoluble compounds through the skin: what are the chances?

    Article • International Journal of Pharmaceutics, November 2023, Elsevier

    Professor Giovanna Rassu

  16. Green Routes for Bio-Fabrication in Biomedical and Pharmaceutical Applications

    Article • Pharmaceutics, June 2023, MDPI AG

    Professor Giovanna Rassu

  17. Conjugation, Prodrug, and Co-Administration Strategies in Support of Nanotechnologies to Improve the Therapeutic Efficacy of Phytochemicals in the Central Nervous System

    Article • Pharmaceutics, May 2023, MDPI AG

    Professor Giovanna Rassu

  18. Sericin/crocetin micro/nanoparticles for nucleus pulposus cells regeneration: An “active” drug delivery system

    Article • Frontiers in Pharmacology, March 2023, Frontiers

    Professor Giovanna Rassu

  19. Improving in vivo oral bioavailability of a poorly soluble drug: a case study on polymeric versus lipid nanoparticles

    Article • Drug Delivery and Translational Research, December 2022, Springer Science + Business Media

    Professor Giovanna Rassu

  20. Novel Utilization of Therapeutic Coatings Based on Infiltrated Encapsulated Rose Bengal Microspheres in Porous Titanium for Implant Applications

    Article • Pharmaceutics, June 2022, MDPI AG

    Professor Giovanna Rassu

  21. Surfactant-Free Chitosan/Cellulose Acetate Phthalate Nanoparticles: An Attempt to Solve the Needs of Captopril Administration in Paediatrics

    Article • Pharmaceuticals, May 2022, MDPI AG

    Professor Giovanna Rassu

  22. Improving Dermal Delivery of Rose Bengal by Deformable Lipid Nanovesicles for Topical Treatment of Melanoma

    Article • Molecular Pharmaceutics, September 2021, American Chemical Society (ACS)

    Professor Giovanna Rassu

  23. Electrochemotherapy of Deep-Seated Tumors: State of Art and Perspectives as Possible “EPR Effect Enhancer” to Improve Cancer Nanomedicine Efficacy

    Article • Cancers, September 2021, MDPI AG

    Professor Giovanna Rassu

  24. Versatile Nasal Application of Cyclodextrins: Excipients and/or Actives?

    Article • Pharmaceutics, July 2021, MDPI AG

    Professor Giovanna Rassu

  25. Crocetin as New Cross-Linker for Bioactive Sericin Nanoparticles

    Article • Pharmaceutics, May 2021, MDPI AG

    Professor Giovanna Rassu

  26. Polymeric and Lipid Nanoparticles: Which Applications in Pediatrics?

    Article • Pharmaceutics, May 2021, MDPI AG

    Professor Giovanna Rassu

  27. Nanotechnology-based rose Bengal: A broad-spectrum biomedical tool

    Article • Dyes and Pigments, April 2021, Elsevier

    Professor Giovanna Rassu

  28. Transmucosal Solid Lipid Nanoparticles to Improve Genistein Absorption via Intestinal Lymphatic Transport

    Article • Pharmaceutics, February 2021, MDPI AG

    Professor Giovanna Rassu

  29. Identifying a Role of Red and White Wine Extracts in Counteracting Skin Aging: Effects of Antioxidants on Fibroblast Behavior

    Article • Antioxidants, February 2021, MDPI AG

    Professor Giovanna Rassu

  30. Polymeric nanomicelles based on inulin D α-tocopherol succinate for the treatment of diabetic retinopathy

    Article • Journal of Drug Delivery Science and Technology, February 2021, Elsevier

    Professor Giovanna Rassu

  31. Nose-to-Brain Delivery of Antioxidants as a Potential Tool for the Therapy of Neurological Diseases

    Article • Pharmaceutics, December 2020, MDPI AG

    Professor Giovanna Rassu

  32. Lipid-based nanocarriers for Rose Bengal dermal delivery: a promising approach in melanoma treatment

    Article • December 2020, MDPI AG

    Professor Giovanna Rassu

  33. Cellulose acetate phthalate-chitosan based nanoparticles for transdermal delivery of captopril in pediatric patients

    Article • December 2020, MDPI AG

    Professor Giovanna Rassu

  34. Solid Lipid Nanoparticles as Formulative Strategy to Increase Oral Permeation of a Molecule Active in Multidrug-Resistant Tuberculosis Management

    Article • Pharmaceutics, November 2020, MDPI AG

    Professor Giovanna Rassu

  35. Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery

    Article • Pharmaceutics, July 2020, MDPI AG

    Professor Giovanna Rassu

  36. Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery

    Article • July 2020, MDPI AG

    Professor Giovanna Rassu

  37. Bio-inspired apatite particles limit skin penetration of drugs for dermatology applications

    Article • Acta Biomaterialia, July 2020, Elsevier

    Dr Christophe Drouet , Professor Giovanna Rassu

  38. Chitosan Nanoparticles for Therapy and Theranostics of Hepatocellular Carcinoma (HCC) and Liver-Targeting

    Article • Nanomaterials, April 2020, MDPI AG

    Professor Giovanna Rassu

  39. <p>Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne</p>

    Article • Clinical Cosmetic and Investigational Dermatology, March 2020, Taylor & Francis

    Professor Giovanna Rassu

  40. Colloidal Apatite Particles : A Multifunctional Platform in (Nano)Medicine

    Article • Juniper Online Journal Material Science, February 2020, Juniper Publishers

    Professor Giovanna Rassu

  41. Indocyanine Green Loaded Polymeric Nanoparticles: Physicochemical Characterization and Interaction Studies with Caco-2 Cell Line by Light and Transmission Electron Microscopy

    Article • Nanomaterials, January 2020, MDPI AG

    Professor Giovanna Rassu

  42. Antibacterial activity of Na-clinoptilolite against Helicobacter pylori: in-vitro tests, synergistic effect with amoxicillin and stability of the antibiotic formulated with the zeolite

    Article • Microporous and Mesoporous Materials, November 2019, Elsevier

    Professor Giovanna Rassu

  43. Harnessing Stem Cells and Neurotrophic Factors with Novel Technologies in the Treatment of Parkinson’s Disease

    Article • Current Stem Cell Research & Therapy, September 2019, Bentham Science Publishers

    Professor Giovanna Rassu

  44. Poly (ethyl 2-cyanoacrylate) nanoparticles (PECA-NPs) as possible agents in tumor treatment

    Article • Colloids and Surfaces B Biointerfaces, May 2019, Elsevier

    Professor Giovanna Rassu

  45. Nanoemulsions for “Nose-to-Brain” Drug Delivery

    Article • Pharmaceutics, February 2019, MDPI AG

    Professor Giovanna Rassu

  46. Increasing protective activity of genistein by loading into transfersomes: A new potential adjuvant in the oxidative stress-related neurodegenerative diseases?

    Article • Phytomedicine, January 2019, Elsevier

    Professor Giovanna Rassu

  47. Intranasal Delivery of Genistein-Loaded Nanoparticles as a Potential Preventive System against Neurodegenerative Disorders

    Article • Pharmaceutics, December 2018, MDPI AG

    Professor Giovanna Rassu

  48. The Role of Combined Penetration Enhancers in Nasal Microspheres on In Vivo Drug Bioavailability

    Article • Pharmaceutics, October 2018, MDPI AG

    Professor Giovanna Rassu

  49. Nanoparticles in detection and treatment of lymph node metastases: an update from the point of view of administration routes

    Article • Expert Opinion on Drug Delivery, October 2018, Taylor & Francis

    Professor Giovanna Rassu

  50. Biodegradable Microspheres as Intravitreal Delivery Systems for Prolonged Drug Release. What is their Eminence in the Nanoparticle Era?

    Article • Current Drug Delivery, July 2018, Bentham Science Publishers

    Paolo Giunchedi, Professor Giovanna Rassu

  51. Hydroxypropyl-β-Cyclodextrin Formulated in Nasal Chitosan Microspheres as Candidate Therapeutic Agent in Alzheimer's Disease

    Article • Current Drug Delivery, June 2018, Bentham Science Publishers

    Paolo Giunchedi, Professor Giovanna Rassu

  52. Aqueous injection of quercetin: An approach for confirmation of its direct in vivo cardiovascular effects

    Article • International Journal of Pharmaceutics, April 2018, Elsevier

    Professor Giovanna Rassu

  53. Lymph node metastases: importance of detection and treatment strategies

    Article • Expert Opinion on Drug Delivery, March 2018, Taylor & Francis

    Professor Giovanna Rassu

  54. Prolonged skin retention of clobetasol propionate by bio-based microemulsions: a potential tool for scalp psoriasis treatment

    Article • Drug Development and Industrial Pharmacy, November 2017, Taylor & Francis

    Paolo Giunchedi, Professor Giovanna Rassu

  55. Engineered polymeric microspheres obtained by multi-step method as potential systems for transarterial embolization and intraoperative imaging of HCC: Preliminary evaluation

    Article • European Journal of Pharmaceutics and Biopharmaceutics, August 2017, Elsevier

    Professor Giovanna Rassu

  56. Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy

    Article • Colloids and Surfaces B Biointerfaces, April 2017, Elsevier

    Professor Giovanna Rassu

  57. In situ forming biodegradable poly(ε-caprolactone) microsphere systems: a challenge for transarterial embolization therapy. In vitro and preliminary ex vivo studies

    Article • Expert Opinion on Drug Delivery, March 2017, Taylor & Francis

    Professor Giovanna Rassu

  58. Natural collagenic skeleton of marine sponges in pharmaceutics: Innovative biomaterial for topical drug delivery

    Article • Materials Science and Engineering C, January 2017, Elsevier

    Professor Giovanna Rassu

  59. Indocyanine green delivery systems for tumour detection and treatments

    Article • Biotechnology Advances, September 2016, Elsevier

    Professor Giovanna Rassu

  60. Neuroprotective Effects of Engineered Polymeric Nasal Microspheres Containing Hydroxypropyl-β-cyclodextrin on β-Amyloid (1-42)–Induced Toxicity

    Article • Journal of Pharmaceutical Sciences, August 2016, Elsevier

    Professor Giovanna Rassu

  61. Bio-based topical system for enhanced salicylic acid delivery: preparation and performance of gels

    Article • Journal of Pharmacy and Pharmacology, June 2016, Oxford University Press (OUP)

    Professor Giovanna Rassu

  62. Particulate formulations based on chitosan for nose-to-brain delivery of drugs. A review

    Article • Journal of Drug Delivery Science and Technology, April 2016, Elsevier

    Professor Giovanna Rassu

  63. Natural zeolites for pharmaceutical formulations: Preparation and evaluation of a clinoptilolite-based material

    Article • Microporous and Mesoporous Materials, March 2016, Elsevier

    Professor Giovanna Rassu

  64. Composite chitosan/alginate hydrogel for controlled release of deferoxamine: A system to potentially treat iron dysregulation diseases

    Article • Carbohydrate Polymers, January 2016, Elsevier

    Professor Giovanna Rassu

  65. Propolis as lipid bioactive nano-carrier for topical nasal drug delivery

    Article • Colloids and Surfaces B Biointerfaces, December 2015, Elsevier

    Professor Giovanna Rassu

  66. Nasal chitosan microparticles target a zidovudine prodrug to brain HIV sanctuaries

    Article • Antiviral Research, November 2015, Elsevier

    Professor Giovanna Rassu

  67. Engineered microparticles based on drug–polymer coprecipitates for ocular-controlled delivery of Ciprofloxacin: influence of technological parameters

    Article • Drug Development and Industrial Pharmacy, October 2015, Taylor & Francis

    Professor Giovanna Rassu

  68. Synthesis of 2‐(Quinoxalin‐2‐ylamino‐benzotriazolyl) Pentanedioic Derivatives as Potential Anti‐Folate Agents

    Article • Journal of Heterocyclic Chemistry, August 2015, Wiley

    Professor Giovanna Rassu

  69. From naturally-occurring neurotoxic agents to CNS shuttles for drug delivery

    Article • European Journal of Pharmaceutical Sciences, July 2015, Elsevier

    Professor Giovanna Rassu

  70. Development of thermosensitive chitosan/glicerophospate injectablein situgelling solutions for potential application in intraoperative fluorescence imaging and local therapy of hepatocellular carcinoma: a preliminary study

    Article • Expert Opinion on Drug Delivery, May 2015, Informa Healthcare

    Professor Giovanna Rassu

  71. Solid microparticles based on chitosan or methyl-β-cyclodextrin: A first formulative approach to increase the nose-to-brain transport of deferoxamine mesylate

    Article • Journal of Controlled Release, March 2015, Elsevier

    Professor Giovanna Rassu

  72. The effect of formulative parameters on the size and physical stability of SLN based on “green” components

    Article • Pharmaceutical Development and Technology, October 2014, Taylor & Francis

    Professor Giovanna Rassu

  73. Encapsulation and modified-release of thymol from oral microparticles as adjuvant or substitute to current medications

    Article • Phytomedicine, October 2014, Elsevier

    Professor Giovanna Rassu

  74. Improvement of thymol properties by complexation with cyclodextrins: In vitro and in vivo studies

    Article • Carbohydrate Polymers, February 2014, Elsevier

    Professor Giovanna Rassu

  75. Transarterial chemoembolization of hepatocellular carcinoma – agents and drugs: an overview. Part 2

    Article • Expert Opinion on Drug Delivery, May 2013, Informa Healthcare

    Professor Giovanna Rassu

  76. Transarterial chemoembolization of hepatocellular carcinoma. Agents and drugs: an overview. Part 1

    Article • Expert Opinion on Drug Delivery, February 2013, Informa Healthcare

    Professor Giovanna Rassu

  77. Influence of polymeric microcarriers on the in vivo intranasal uptake of an anti-migraine drug for brain targeting

    Article • European Journal of Pharmaceutics and Biopharmaceutics, February 2013, Elsevier

    Professor Pasquale Bandiera, Professor Giovanna Rassu

  78. Evaluation of the effect of hydroxypropyl-β-cyclodextrin on topical administration of milk thistle extract

    Article • Carbohydrate Polymers, January 2013, Elsevier

    Professor Giovanna Rassu

  79. Studies of Technological Parameters Influencing the Protein-Polymeric Nanoparticles Adsorption Process for Transmucosal Administration

    Article • Current Nanoscience, November 2012, Bentham Science Publishers

    Professor Giovanna Rassu

  80. Mucoadhesive Drug Delivery Systems for Nose-to-Brain Targeting of Dopamine

    Article • Journal of Nanoneuroscience, April 2012, American Scientific Publishers

    Professor Giovanna Rassu

  81. Solid lipid nanoparticles with and without hydroxypropyl-β-cyclodextrin: a comparative study of nanoparticles designed for colonic drug delivery

    Article • Nanotechnology, February 2012, Institute of Physics Publishing

    Professor Giovanna Rassu

  82. Surface Thermodynamics of Mucoadhesive Dry Powder Formulation of Zolmitriptan

    Article • AAPS PharmSciTech, September 2011, Springer Science + Business Media

    Professor Giovanna Rassu

  83. Influence of Chitosan Glutamate on the in vivo Intranasal Absorption of Rokitamycin from Microspheres

    Article • Journal of Pharmaceutical Sciences, April 2011, Elsevier

    Professor Giovanna Rassu

  84. Development of solid nanoparticles based on hydroxypropyl-β-cyclodextrin aimed for the colonic transmucosal delivery of diclofenac sodium

    Article • Journal of Pharmacy and Pharmacology, February 2011, Oxford University Press (OUP)

    Professor Giovanna Rassu

  85. New chitosan derivatives for the preparation of rokitamycin loaded microspheres designed for ocular or nasal administration

    Article • Journal of Pharmaceutical Sciences, December 2009, Elsevier

    Professor Giovanna Rassu

  86. Evaluation of solid lipid microparticles produced by spray congealing for topical application of econazole nitrate

    Article • Journal of Pharmacy and Pharmacology, May 2009, Oxford University Press (OUP)

    Professor Giovanna Rassu

  87. Frontal polymerization as a new method for developing drug controlled release systems (DCRS) based on polyacrylamide

    Article • European Polymer Journal, March 2009, Elsevier

    Professor Alberto Mariani, Professor Giovanna Rassu

  88. Mucoadhesive microspheres for nasal administration of cyclodextrins

    Article • Journal of Drug Targeting, January 2009, Taylor & Francis

    Professor Giovanna Rassu

  89. Preparation, In Vitro Characterization and Preliminary In Vivo Evaluation of Buccal Polymeric Films Containing Chlorhexidine

    Article • AAPS PharmSciTech, November 2008, Springer Science + Business Media

    Professor Giovanna Rassu

  90. Improvement of Antiamoebic Activity of Rokitamycin Loaded in Chitosan Microspheres

    Article • The Open Drug Delivery Journal, June 2008, Bentham Science Publishers

    Dr Mattana A Antonella, Professor Giovanna Rassu

  91. A New Sensitive Reversed‐phase High‐performance Liquid Chromatography Method for the Quantitative Determination of Metoclopramide in Canine Plasma

    Article • Analytical Letters, April 2008, Taylor & Francis

    Professor Giovanna Rassu

  92. Spray-dried microspheres based on methylpyrrolidinone chitosan as new carrier for nasal administration of metoclopramide

    Article • European Journal of Pharmaceutics and Biopharmaceutics, February 2008, Elsevier

    Professor Giovanna Rassu

  93. Ketoprofen Spray-dried Microspheres Based on Eudragit® RS and RL: Study of the Manufacturing Parameters

    Article • Drug Development and Industrial Pharmacy, January 2008, Taylor & Francis

    Professor Giovanna Rassu

  94. Solid lipid nanoparticles (SLN) as carriers for the topical delivery of econazole nitrate: in-vitro characterization, ex-vivo and in-vivo studies

    Article • Journal of Pharmacy and Pharmacology, August 2007, Oxford University Press (OUP)

    Professor Giovanna Rassu

  95. Nasal administration of Carbamazepine using chitosan microspheres: In vitro/in vivo studies

    Article • International Journal of Pharmaceutics, January 2006, Elsevier

    Professor Giovanna Rassu

  96. Mucoadhesive microspheres for nasal administration of an antiemetic drug, metoclopramide: in-vitro/ex-vivo studies

    Article • Journal of Pharmacy and Pharmacology, March 2005, Oxford University Press (OUP)

    Professor Giovanna Rassu