All Stories

  1. Conserved neutrophil degranulation transcripts in HIV-TB coinfected children across East and Southern Africa
  2. Decade-long antiretroviral therapy in Uganda: Population-health outcomes from a national HIV treatment cohort, 2014–2024
  3. rMAP 2.0: A modular, reproducible and scalable WDL-Cromwell-Docker workflow for genomic analysis of ESKAPEE pathogens
  4. Multicountry genomic analysis underscores regional cholera spread in Africa
  5. Pathways, outputs and impact of NIH-supported bioinformatics and genomics graduate trainees in Africa
  6. Harnessing Genomics for Public Health: Use-Case Insights from Uganda
  7. Burden of sickle cell anemia in Africa: A systematic review and meta-analysis
  8. A clinical milestone for CRISPR in sickle-cell disease
  9. Reimagining Tuberculosis Control in the Era of Genomics: The Case for Global Investment in Mycobacterium tuberculosis Genomic Surveillance
  10. Genomic characterization of Citrobacter freundii clinical isolates from Tanzania
  11. Extracellular hydrolytic enzyme activities and biofilm formation in Candida species isolated from people living with human immunodeficiency virus with oropharyngeal candidiasis at HIV/AIDS clinics in Uganda
  12. Unlocking the future of complex human diseases prediction: multi-omics risk score breakthrough
  13. High KIR diversity in Uganda and Botswana children living with HIV
  14. Machine learning-based prediction of antibiotic resistance in Mycobacterium tuberculosis clinical isolates from Uganda
  15. Reported prevalence and comparison of diagnostic approaches for Candida africana: a systematic review with meta-analysis
  16. Whole genome-based characterization of extended-spectrum β-lactamase-producing Enterobacter cloacae from orthopedic patients and environment of a tertiary referral hospital in Tanzania
  17. Multicountry genomic analysis underscores regional cholera spread in Africa
  18. Inclusiveness of the All of Us Research Program improves polygenic risk scores and fosters genomic medicine for all
  19. Serological Status of Vaccine and Hepatitis B Virus Exposure Among Children Under 5 and Aged 15–17 Years in Kampala, Uganda
  20. Lack of Candida africana in Ugandan pregnant women: results from a pilot study using MALDI-ToF
  21. The rise of pathogen genomics in Africa
  22. Africa in the era of pathogen genomics: Unlocking data barriers
  23. Metagenomics insights into the microbial resistome and virulome composition of Kampala’s wastewater
  24. CDC Trioplex diagnostic assay underperforms in detection of circulating Chikungunya West African genotype
  25. The pandemic agreement: an African perspective
  26. HIV-DRIVES: HIV drug resistance identification, variant evaluation, and surveillance pipeline
  27. HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance Pipeline
  28. Genomic epidemiology uncovers the timing and origin of the emergence of mpox in humans
  29. Molecular epidemiology of recurrent zoonotic transmission of mpox virus in West Africa
  30. Varied Prevalence of Antimalarial Drug Resistance Markers in Different Populations of Newly Arrived Refugees in Uganda
  31. Prevalence of Oropharyngeal Candidiasis and distribution of Candida species among People Living with Human Immunodeficiency Virus in Africa: a systematic review and meta-analysis
  32. The rise of pathogen genomics in Africa
  33. Peer Review of “Establishing Antimicrobial Resistance Surveillance in the Water and Environment Sector in a Resource-Limited Setting: Methodical Qualitative and Quantitative Description of Uganda’s Experience From 2021 to 2023”
  34. In Vitro Evaluation of the Virulence Attributes of Oropharyngeal Candida Species Isolated from People Living with Human Immunodeficiency Virus with Oropharyngeal Candidiasis on Antiretroviral Therapy
  35. HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance Pipeline
  36. The dawn of a cure for sickle cell disease through CRISPR‐based treatment: A critical test of equity in public health genomics
  37. Generalizability of machine learning in predicting antimicrobial resistance in E. coli: a multi-country case study in Africa
  38. Climate-influenced vector-borne diseases in Africa: a call to empower the next generation of African researchers for sustainable solutions
  39. Distribution and antifungal susceptibility profile of oropharyngeal Candida species isolated from people living with HIV in the era of universal test and treat policy in Uganda
  40. A systematic review reveals that African children of 15–17 years demonstrate low hepatitis B vaccine seroprotection rates
  41. A Digital One Health framework to integrate data for public health decision-making
  42. Virulence genes and plasmid replicon profiles of selected β-lactamase-producing Acinetobacter baumannii from orthopaedic patients and the environment in a tertiary referral hospital in Tanzania, East Africa
  43. Reviewing the journey to the clinical application of bacteriophages to treat multi-drug-resistant bacteria
  44. HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance Pipeline
  45. Unraveling virulence determinants in extended-spectrum beta-lactamase-producing Escherichia coli from East Africa using whole-genome sequencing
  46. Reduced CCR5 expression among Uganda HIV controllers
  47. Unlocking the Potential of Genomic Data to Inform Typhoid Fever Control Policy: Supportive Resources for Genomic Data Generation, Analysis, and Visualization
  48. A pan-African pathogen genomics data sharing platform to support disease outbreaks
  49. Metatranscriptomic analysis of the gut microbiome of black soldier fly larvae reared on lignocellulose-rich fiber diets unveils key lignocellulolytic enzymes
  50. Impact of high human genetic diversity in Africa on immunogenicity and efficacy of RTS,S/AS01 vaccine
  51. Antimicrobial susceptibility surveillance and antimicrobial resistance in Neisseria gonorrhoeae in Africa from 2001 to 2020: A mini-review
  52. No association of a Vascular endothelial growth factor A (VEGFA) gene polymorphism with pre-eclampsia among pregnant women in Uganda
  53. Molecular Epidemiology and Diversity of SARS-CoV-2 in Ethiopia, 2020–2022
  54. Prevalence and antimicrobial resistance profiles of Neisseria gonorrhea and Chlamydia trachomatis isolated from individuals attending STD clinics in Kampala, Uganda
  55. The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
  56. Microbial characteristics of dental caries in HIV positive individuals
  57. Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus
  58. Phylogenetic lineages of tuberculosis isolates and their association with patient demographics in Tanzania
  59. Next-generation sequencing (NGS) reveals low-abundance HIV-1 drug resistance mutations among patients experiencing virological failure at the time of therapy switching in Uganda
  60. Workshop-based learning and networking: a scalable model for research capacity strengthening in low- and middle-income countries
  61. Medical Mycology dissertation topics require prioritisation among Postgraduate Microbiology trainees of Makerere University, Uganda
  62. First report of whole-genome analysis of an extensively drug-resistant Mycobacterium tuberculosis clinical isolate with bedaquiline, linezolid and clofazimine resistance from Uganda
  63. The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
  64. Genetic Diversity, Distribution, and Genomic Characterization of Antibiotic Resistance and Virulence of Clinical Pseudomonas aeruginosa Strains in Kenya
  65. Genetic Diversity of Bundibugyo Ebolavirus from Uganda and the Democratic Republic of Congo
  66. Bioinformatics mentorship in a resource limited setting
  67. Transmission Dynamics of Antimicrobial Resistance at a National Referral Hospital in Uganda
  68. Whole-genome sequencing of SARS-CoV-2 in Uganda: implementation of the low-cost ARTIC protocol in resource-limited settings
  69. Knowledge and attitude of secondary school students in Nakaseke, Uganda towards HIV transmission and treatment
  70. rMAP: the Rapid Microbial Analysis Pipeline for ESKAPE bacterial group whole-genome sequence data
  71. Increasing Antimicrobial Resistance in Surgical Wards at Mulago National Referral Hospital, Uganda, from 2014 to 2018—Cause for Concern?
  72. Knowledge and attitude of secondary school students in Nakaseke, Uganda towards HIV transmission and treatment
  73. Efficacy of Face Masks Used in Uganda: A Laboratory-Based Inquiry during the COVID-19 Pandemic
  74. Gastrointestinal Tract Colonization Rate of Extended-Spectrum Beta-Lactamase-Producing Gram-Negative Bacteria and Associated Factors Among Orthopaedic Patients in a Tertiary Hospital in Tanzania: Implications for Infection Prevention
  75. Genomics and bioinformatics capacity in Africa: no continent is left behind
  76. Unmapped exome reads implicate a role for Anelloviridae in childhood HIV-1 long-term non-progression
  77. Face-Masking, an Acceptable Protective Measure against COVID-19 in Ugandan High-Risk Groups
  78. Efficacy of face-masks used in Uganda: a laboratory-based inquiry during the COVID-19 pandemic
  79. Re-thinking antimicrobial resistance transmission dynamics: a meta-analysis of cross-sectional studies at referral hospitals in Uganda
  80. Variations in Trim5α and Cyclophilin A genes among HIV-1 elite controllers and non controllers in Uganda: a laboratory-based cross-sectional study
  81. Whole-genome sequence analysis reveals evolution of antimicrobial resistance in a Ugandan colistin resistant Acinetobacter baumannii
  82. High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda
  83. Current and emerging diagnostic tests available for the novel COVID-19 global pandemic
  84. blaVIM- and blaOXA-mediated carbapenem resistance among Acinetobacter baumannii and Pseudomonas aeruginosa isolates from the Mulago hospital intensive care unit in Kampala, Uganda
  85. Whole-genome sequence analysis of Vibrio cholerae from three outbreaks in Uganda, 2014 - 2016
  86. Comprehensive genomic analysis of Vibrio cholerae from three outbreaks in Uganda, 2014 - 2016
  87. Role of genomics literacy in reducing the burden of common genetic diseases in Africa
  88. Investigating colistin drug resistance: The role of high-throughput sequencing and bioinformatics
  89. Investigating colistin drug resistance: The role of high-throughput sequencing and bioinformatics
  90. The Collaborative African Genomics Network (CAfGEN): Applying Genomic technologies to probe host factors important to the progression of HIV and HIV-tuberculosis infection in sub-Saharan Africa
  91. Whole-Exome Sequencing Reveals Uncaptured Variation and Distinct Ancestry in the Southern African Population of Botswana
  92. Microbial contaminants isolated from items and work surfaces in the post- operative ward at Kawolo general hospital, Uganda
  93. Human Genomic Loci Important in Common Infectious Diseases: Role of High-Throughput Sequencing and Genome-Wide Association Studies
  94. The collaborative African genomics network training program: a trainee perspective on training the next generation of African scientists
  95. Serological and molecular investigation for brucellosis in swine in selected districts of Uganda
  96. Cough Aerosol Cultures of Mycobacterium tuberculosis: Insights on TST / IGRA Discordance and Transmission Dynamics
  97. High Genotypic Discordance of Concurrent Mycobacterium tuberculosis Isolates from Sputum and Blood of HIV-Infected Individuals
  98. Improving the Sensitivity of the Xpert MTB/RIF Assay on Sputum Pellets by Decreasing the Amount of Added Sample Reagent: a Laboratory and Clinical Evaluation
  99. Feasibility of establishing a biosafety level 3 tuberculosis culture laboratory of acceptable quality standards in a resource-limited setting: an experience from Uganda
  100. Seroprevalence of Syphilis among Human Immunodeficiency Virus Positive Individuals Attending Immune Suppressed Syndrome Clinic at International Hospital Kampala, Uganda
  101. Isolation and Molecular Characterization ofBrucellaIsolates in Cattle Milk in Uganda
  102. Rifampicin resistance mutations in the 81 bp RRDR of rpoB gene in Mycobacterium tuberculosis clinical isolates using Xpert®MTB/RIF in Kampala, Uganda: a retrospective study
  103. Genetics of Sub-Saharan African Human Population: Implications for HIV/AIDS, Tuberculosis, and Malaria
  104. Clinico-pathological features of tuberculosis due to Mycobacterium tuberculosis Uganda genotype in patients with tuberculous lymphadenitis: a cross sectional study
  105. Tuberculosis and Genetics of Sub-Saharan Africa Human Population
  106. Sensititre MYCOTB MIC Plate for Testing Mycobacterium tuberculosis Susceptibility to First- and Second-Line Drugs
  107. Cough Aerosols of Mycobacterium tuberculosis Predict New Infection. A Household Contact Study
  108. Species and genotypic diversity of non-tuberculous mycobacteria isolated from children investigated for pulmonary tuberculosis in rural Uganda
  109. An Early Morning Sputum Sample Is Necessary for the Diagnosis of Pulmonary Tuberculosis, Even with More Sensitive Techniques: A Prospective Cohort Study among Adolescent TB-Suspects in Uganda