All Stories

  1. Induction of liver fibrosis by CCl4 mediates pathological alterations in the spleen and lymph nodes: The potential therapeutic role of propolis
  2. Synthesis of a novel series of (Z)-3,5-disubstituted thiazolidine-2,4-diones as promising anti-breast cancer agents
  3. Exposure to radioactive rocks from the Egyptian eastern desert attenuates the efficiency of the immune organs and induces apoptosis of blood lymphocytes in rat model
  4. Enhanced susceptibility to apoptosis and growth arrest of human breast carcinoma cells treated with silica nanoparticles loaded with monohydroxy flavone compounds
  5. The Therapeutic Mechanisms of Propolis Against CCl4-Mediated Liver Injury by Mediating Apoptosis of Activated Hepatic Stellate Cells and Improving the Hepatic Architecture through PI3K/AKT/mTOR, TGF-β/Smad2, Bcl2/BAX/P53 and iNOS Signaling Pathways
  6. Camel Whey Protein Disrupts the Cross-Talk Between PI3K and BCL-2 Signals and Mediates Apoptosis in Primary Acute Myeloid Leukemia Cells
  7. Curcumin analogue 1,5-bis(4-hydroxy-3-((4-methylpiperazin-1-yl)methyl)phenyl)penta-1,4-dien-3-one mediates growth arrest and apoptosis by targeting the PI3K/AKT/mTOR and PKC-theta signaling pathways in human breast carcinoma cells
  8. Protective effects of camel whey protein against scrotal heat-mediated damage and infertility in the mouse testis through YAP/Nrf2 and PPAR-gamma signaling pathways
  9. Ameliorative role of camel whey protein and rosuvastatin on induced dyslipidemia in mice
  10. Camel whey protein protects lymphocytes from apoptosis via the PI3K/AKT, NF-κB, ATF-3 and HSP-70 signaling pathways in heat-stressed male mice
  11. Increased total antioxidant capacity in renal tissue of female BWF1 mice infected with Plasmodium chabaudi
  12. Wound healing: time to look for intelligent, ‘natural’ immunological approaches?
  13. Camel whey protein improves oxidative stress and histopathological alterations in lymphoid organs through Bcl-XL/Bax expression in a streptozotocin-induced type 1 diabetic mouse model
  14. Interaction of anticancer drug clofarabine with human serum albumin and human α-1 acid glycoprotein. Spectroscopic and molecular docking approach
  15. Fibrillogenesis of human serum albumin in the presence of levodopa – spectroscopic, calorimetric and microscopic studies
  16. Camel Whey Protein Protects B and T Cells from Apoptosis by Suppressing Activating Transcription Factor-3 (ATF-3)-Mediated Oxidative Stress and Enhancing Phosphorylation of AKT and IκB-α in Type I Diabetic Mice
  17. Effects of royal jelly supplementation on regulatory T cells in children with SLE
  18. Camel whey protein improves lymphocyte function and protects against diabetes in the offspring of diabetic mouse dams
  19. Biophysical insights into the interaction of hen egg white lysozyme with therapeutic dye clofazimine: modulation of activity and SDS induced aggregation of model protein
  20. Differential mode of interaction of ThioflavinT with native β structural motif in human α 1-acid glycoprotein and cross beta sheet of its amyloid: Biophysical and molecular docking approach
  21. Effect of administration timing of postchemotherapy granulocyte colony-stimulating factor on host-immune cell recovery and CD8+ T-cell response
  22. Insight into the interaction of antitubercular and anticancer compound clofazimine with human serum albumin: spectroscopy and molecular modelling
  23. Altered renal immune complexes deposition in female BWF1 lupus mice following Plasmodium chabaudi infection
  24. Bee Venom Accelerates Wound Healing in Diabetic Mice by Suppressing Activating Transcription Factor-3 (ATF-3) and Inducible Nitric Oxide Synthase (iNOS)-Mediated Oxidative Stress and Recruiting Bone Marrow-Derived Endothelial Progenitor Cells
  25. Biophysical and molecular docking insight into interaction mechanism and thermal stability of human serum albumin isoforms with a semi-synthetic water-soluble camptothecin analog irinotecan hydrochloride
  26. Thymoquinone Rescues T Lymphocytes from Gamma Irradiation-Induced Apoptosis and Exhaustion by Modulating Pro-Inflammatory Cytokine Levels and PD-1, Bax, and Bcl-2 Signaling
  27. Temperature dependent rapid annealing effect induces amorphous aggregation of human serum albumin
  28. Propolis and bee venom in diabetic wounds; a potential approach that warrants clinical investigation
  29. Elevated IFN-alpha/beta levels in a streptozotocin-induced type I diabetic mouse model promote oxidative stress and mediate depletion of spleen-homing CD8+ T cells by apoptosis through impaired CCL21/CCR7 axis and IL-7/CD127 signaling
  30. Cytotoxic cardenolides from the latex of Calotropis procera
  31. Oral supplementation of diabetic mice with propolis restores the proliferation capacity and chemotaxis of B and T lymphocytes towards CCL21 and CXCL12 by modulating the lipid profile, the pro-inflammatory cytokine levels and oxidative stress
  32. Biophysical and molecular docking insight into the interaction of cytosine β-D arabinofuranoside with human serum albumin
  33. Effect of a high fat, high sucrose diet on the promotion of non-alcoholic fatty liver disease in male rats: the ameliorative role of three natural compounds
  34. Inhibitory effect of copper nanoparticles on rosin modified surfactant induced aggregation of lysozyme
  35. Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFκB and ERK
  36. Thermal induced unfolding of human serum albumin isomers: Assigning residual α helices to domain II
  37. Increased Levels of Type 1 Interferon in a Type 1 Diabetic Mouse Model Induce the Elimination of B Cells from the Periphery by Apoptosis and Increase their Retention in the Spleen
  38. Topical Application of Propolis Enhances Cutaneous Wound Healing by Promoting TGF-Beta/Smad-Mediated Collagen Production in a Streptozotocin-Induced Type I Diabetic Mouse Model
  39. The Surfactant-Induced Conformational and Activity Alterations in Rhizopus niveus Lipase
  40. Analysis of Binding Interaction Between Antibacterial Ciprofloxacin and Human Serum Albumin by Spectroscopic Techniques
  41. Harmful Effect of Detergents on Lipase
  42. Interaction of the 5-fluorouracil analog 5-fluoro-2′-deoxyuridine with ‘N’ and ‘B’ isoforms of human serum albumin: a spectroscopic and calorimetric study
  43. Increased Susceptibility to Apoptosis and Growth Arrest of Human Breast Cancer Cells Treated by a Snake Venom-Loaded Silica Nanoparticles
  44. Therapeutic efficacy and molecular mechanisms of snake (Walterinnesia aegyptia) venom-loaded silica nanoparticles in the treatment of breast cancer- and prostate cancer-bearing experimental mouse models
  45. Concentration-dependent antagonistic persuasion of SDS and naphthalene derivatives on the fibrillation of stem bromelain
  46. Cosolvents Induced Unfolding and Aggregation of Keyhole Limpet Hemocyanin
  47. Enhanced anticancer efficacy of snake venom combined with silica nanoparticles in a murine model of human multiple myeloma: Molecular targets for cell cycle arrest and apoptosis induction
  48. Differences in prostate cancer detection between Canadian and Saudi populations
  49. Blocking Type I Interferon Signaling Rescues Lymphocytes from Oxidative Stress, Exhaustion, and Apoptosis in a Streptozotocin-Induced Mouse Model of Type I Diabetes
  50. Camel whey protein enhances diabetic wound healing in a streptozotocin-induced diabetic mouse model: the critical role of β-Defensin-1, -2 and -3
  51. Malarial Infection of Female BWF1 Lupus Mice Alters the Redox State in Kidney and Liver Tissues and Confers Protection against Lupus Nephritis
  52. Maternal supplementation of diabetic mice with thymoquinone protects their offspring from abnormal obesity and diabetes by modulating their lipid profile and free radical production and restoring lymphocyte proliferation via PI3K/AKT signaling
  53. Snake (Walterinnesia aegyptia) venom-loaded silica nanoparticles induce apoptosis and growth arrest in human prostate cancer cells
  54. Cellular and Molecular Mechanisms Underlie the Anti-Tumor Activities Exerted by Walterinnesia aegyptia Venom Combined with Silica Nanoparticles against Multiple Myeloma Cancer Cell Types
  55. Modulation of immune cell proliferation and chemotaxis towards CC chemokine ligand (CCL)-21 and CXC chemokine ligand (CXCL)-12 in undenatured whey protein-treated mice
  56. Synthesis of double mesoporous core–shell silica spheres with tunable core porosity and their drug release and cancer cell apoptosis properties
  57. Notice of disputed authorship to: Vitamin C supplementation reconstitutes polyfunctional T cells in streptozotocin-induced diabetic rats
  58. Thymoquinone and vitamin E supplementation improve the reproductive characteristics of heat stressed male mice
  59. Silica Nanoparticles Sensitize Human Multiple Myeloma Cells to Snake (Walterinnesia aegyptia) Venom-Induced Apoptosis and Growth Arrest
  60. Immunoenhancing property of dietary un-denatured whey protein derived from three camel breeds in mice
  61. Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1α, MIP-2, KC, CX3CL1 and TGF-β in wounded tissue
  62. Supplementation with Undenatured Whey Protein During Diabetes Mellitus Improves the Healing and Closure of Diabetic Wounds through the Rescue of Functional Long-lived Wound Macrophages
  63. Thymoquinone ameliorates the immunological and histological changes induced by exposure to imidacloprid insecticide
  64. Human breast carcinoma cells are induced to apoptosis by samsum ant venom through an IGF-1-dependant pathway, PI3K/AKT and ERK signaling
  65. Induction of Apoptosis and Growth Arrest in Human Breast Carcinoma Cells by a Snake (Walterinnesia aegyptia) Venom Combined With Silica Nanoparticles: Crosstalk Between Bcl2 and Caspase 3
  66. Revisiting the B-cell compartment in mouse and humans: more than one B-cell subset exists in the marginal zone and beyond
  67. Walterinnesia aegyptia venom combined with silica nanoparticles enhances the functioning of normal lymphocytes through PI3K/AKT, NFkappaB and ERK signaling
  68. CXC chemokine ligand 12 (CXCL12) via its cognate receptor (CXCR4) controls the chemotaxis of multiple myeloma cell line (U266) via PI3K/AKT, PLCβ3, RhoA, NFκB and ERK1/2
  69. Effects of vitamin E and thymoquinone on physiological and histological characteristics of heat-stressed male mice
  70. Immunological and histological effects of exposure to imidacloprid insecticide in male albino rats
  71. Thymoquinone Inhibits the CXCL12-Induced Chemotaxis of Multiple Myeloma Cells and Increases Their Susceptibility to Fas-Mediated Apoptosis
  72. T lymphocytes from malnourished infants are short-lived and dysfunctional cells
  73. Vitamin C supplementation reconstitutes polyfunctional T cells in streptozotocin-induced diabetic rats
  74. Maternal Perinatal Undernutrition Attenuates T-Cell Function in Adult Male Rat Offspring
  75. Perinatal supplementation with thymoquinone improves diabetic complications and T cell immune responses in rat offspring
  76. Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-XL expression
  77. Effects of undenatured whey protein supplementation on CXCL12- and CCL21-mediated B and T cell chemotaxis in diabetic mice
  78. Erratum
  79. Comparison of Immune Restoration in Early versus Late Alpha Interferon Therapy against Hepatitis C Virus
  80. Changes in Placental Size during Ramadan
  81. Blocking Type I Interferon (IFN) Signaling Impairs Antigen Responsiveness of Circulating Lymphocytes and Alters Their Homing to Lymphoid Organs: Protective Role of Type I IFN
  82. Type I interferon (IFN-α/β) rescues B-lymphocytes from apoptosis via PI3Kδ/Akt, Rho-A, NFκB and Bcl-2/BclXL
  83. HLA-G and its relation to proliferation index in detection and monitoring breast cancer patients
  84. 265 Early but not late interferon alpha therapy against hepatitis C rescues polyfunctional CD4+ and CD8+ memory T cells
  85. Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8+ Memory T Cells
  86. BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells
  87. HIV Type 1 Glycoprotein 120 Inhibits Human B Cell Chemotaxis to CXC Chemokine Ligand (CXCL) 12, CC Chemokine Ligand (CCL)20, and CCL21
  88. IFN  enhances human B-cell chemotaxis by modulating ligand-induced chemokine receptor signaling and internalization