All Stories

  1. Regioselective Introduction of Indolin-3-one Moieties to Substituted Heteroaromatic Compounds
  2. Cover Feature: Copper‐Catalyzed Synthesis of C‐2 Substituted Indolin‐3‐Ones and Indolin‐3‐One [4+2] Cycloadducts Through Azide‐Tethered Iodonium Ylides (Asian J. Org. Chem. 5/2025)
  3. Copper‐Catalyzed Synthesis of C‐2 Substituted Indolin‐3‐Ones and Indolin‐3‐One [4+2] Cycloadducts Through Azide‐Tethered Iodonium Ylides
  4. Structure-Based Discovery of Allosteric Inhibitors Targeting a New Druggable Site in the Respiratory Syncytial Virus Polymerase
  5. Proof of concept: Pull down assay using bovine serum albumin and an immunomodulator small molecule
  6. Stereoselective Intramolecular [2+2] Trapping of 1,2‐Cyclohexadienes: a Route to Rigid, Angularly Fused Tricyclic Scaffolds
  7. 2 + 2 Trapping of Acyloxy-1,2-cyclohexadienes with Styrenes and Electron-Deficient Olefins
  8. Repurposing Antimalarial Pyronaridine as a DNA Repair Inhibitor to Exploit the Full Potential of Gold-Nanoparticle-Mediated Radiation Response
  9. PET Imaging of Fructose Metabolism in a Rodent Model of Neuroinflammation with 6-[18F]fluoro-6-deoxy-D-fructose
  10. A Fluorescence-Based Assay to Probe Inhibitory Effect of Fructose Mimics on GLUT5 Transport in Breast Cancer Cells
  11. Towards Selective Binding to the GLUT5 Transporter: Synthesis, Molecular Dynamics and In Vitro Evaluation of Novel C-3-Modified 2,5-Anhydro-D-mannitol Analogs
  12. Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition
  13. Cover Feature: Lithium Hydroxide Assisted Endo ‐Selective [4+4]‐Photocycloaddition of Pyran‐2‐ones (Eur. J. Org. Chem. 16/2021)
  14. Lithium Hydroxide Assisted Endo ‐Selective [4+4]‐Photocycloaddition of Pyran‐2‐ones
  15. Pharmacological targets and emerging treatments for respiratory syncytial virus bronchiolitis
  16. Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1–XPF-mediated DNA repair
  17. Design, synthesis, and evaluation of positron emission tomography/fluorescence dual imaging probes for targeting facilitated glucose transporter 1 (GLUT1)
  18. Generation and trapping of electron-deficient 1,2-cyclohexadienes. Unexpected hetero-Diels–Alder reactivity
  19. Design, synthesis and in vitro cell-free/cell-based biological evaluations of novel ERCC1-XPF inhibitors targeting DNA repair pathway
  20. A Mild Method for the Generation and Interception of 1,2-Cycloheptadienes with 1,3-Dipoles
  21. Computer‐aided drug design of small molecule inhibitors of the ERCC1‐XPF protein–protein interaction
  22. Comprehensive in vitro characterization of PD-L1 small molecule inhibitors
  23. Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1–XPF
  24. Strain-Activated Diels–Alder Trapping of 1,2-Cyclohexadienes: Intramolecular Capture by Pendent Furans
  25. Asymmetric synthesis of (+)-laurencin using a stereoselective Stevens [1,2]-shift of a sulfonium ylide
  26. The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C
  27. Dual Catalytic Synthesis of Antiviral Compounds Based on Metallocarbene–Azide Cascade Chemistry
  28. One-Pot Generation of Bicyclo[3.1.0]hexanols and Cyclohexanones by Double Interrupted Nazarov Reactions
  29. Molecular Imaging of GLUT1 and GLUT5 in Breast Cancer: A Multitracer Positron Emission Tomography Imaging Study in Mice
  30. Synthesis and biological evaluation of structurally simplified noscapine analogues as microtubule binding agents
  31. Tunable GLUT-Hexose Binding and Transport via Modulation of Hexose C-3 Hydrogen-Bonding Capabilities
  32. Intercepting the Nazarov Oxyallyl Intermediate with α-Formyl­vinyl Anion Equivalents to Access Formal Morita–Baylis–Hillman Alkylation Products
  33. Oxidation‐Initiated Cyclizations of Pentadienyl Ethers: An Alternative Entry to the Nazarov Reaction
  34. Oxidation‐Initiated Cyclizations of Pentadienyl Ethers: An Alternative Entry to the Nazarov Reaction
  35. Fluorescent Hexose Conjugates Establish Stringent Stereochemical Requirement by GLUT5 for Recognition and Transport of Monosaccharides
  36. Medium-Sized Cyclic Ethers via Stevens [1,2]-Shift of Mixed Monothioacetal-Derived Sulfonium Ylides: Application to Formal Synthesis of (+)-Laurencin
  37. Evidence for heterolytic cleavage of a cyclic oxonium ylide: implications for the mechanism of the Stevens [1,2]-shift
  38. Interrupting the Nazarov Cyclization with Bromine
  39. Structures reveal details of small molecule binding to cardiac troponin
  40. Efficient Trapping of 1,2-Cyclohexadienes with 1,3-Dipoles
  41. A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation
  42. Efficient and Easy Access to Optically Pure Tetrasubstituted Tetra­hydrofurans via Stereoselective Opening ofC2-Symmetric Epoxide and Aziridine Rings
  43. 1,4‐Diketones from Cross‐Conjugated Dienones: Potassium Permanganate‐Interrupted Nazarov Reaction
  44. Diastereoselective N-quaternization of piperidines
  45. Reactivity and Stereoselectivity of 6π and Nazarov Electrocyclizations of Bridged Bicyclic Trienes and Divinyl Ketones
  46. New fluorinated fructose analogs as selective probes of the hexose transporter protein GLUT5
  47. Correction: New fluorinated fructose analogs as selective probes of the hexose transporter protein GLUT5
  48. Experimental and Computational Studies on Interrupted Nazarov Reactions: Exploration of Umpolung Reactivity at the α-Carbon of Cyclopentanones
  49. Formal Homologous Aldol Reactions: Interrupting the Nazarov Cyclization via Carboalkoxylation of Alkynes
  50. Ready Access to Alkylidenecyclopentenones by Nazarov Cyclization/β-Elimination of 2-Hydroxyalkyl-1,4-dien-3-ones
  51. α-Hydroxycyclopentanones via one-pot oxidation of the trimethylaluminum-mediated Nazarov reaction with triplet oxygen
  52. Azide trapping of metallocarbenes: generation of reactive C-acylimines and domino trapping with nucleophiles
  53. Efficient synthesis of bicyclo[6.3.0]undecadienones by Nazarov cyclization/regioselective elimination
  54. ChemInform Abstract: Organoaluminum‐Mediated Interrupted Nazarov Reaction.
  55. Hydroxylic additives enhance yield and scalability of silicon-directed Nazarov reaction
  56. Organoaluminum‐Mediated Interrupted Nazarov Reaction
  57. Organoaluminum‐Mediated Interrupted Nazarov Reaction
  58. Nazarov Reactions of Vinyl Cyclopropylamines: An Approach to the Imino-Nazarov Problem
  59. Intramolecular generation and rearrangement of oxonium ylides: methodology studies and their application in synthesis
  60. Prion inhibition with multivalent PrPSc binding compounds
  61. Regioselective synthesis of 2-iminooxazinones from dioxinones and carbodiimides
  62. Superacid-catalyzed Friedel–Crafts cyclization of unactivated alkenes
  63. Lithium Hydroperoxide
  64. Construction of α-amido-indanones via formal allenamide hydroacylation–Nazarov cyclization
  65. Preparation and Synthetic Applications of Azetidines
  66. Homologous Mukaiyama Reactions via Trapping of the Nazarov Intermediate with Silyloxyalkenes
  67. Radiopharmacological evaluation of 6-deoxy-6-[18F]fluoro-d-fructose as a radiotracer for PET imaging of GLUT5 in breast cancer
  68. Expedient Route to the Tigliane-Daphnane Skeleton via Oxonium Ylide [1,2]-Shift
  69. Intermolecular [3 + 3]-Cycloadditions of Azides with the Nazarov Intermediate
  70. Olefination of α,α′-Divinyl Ketones through Catalytic Meyer−Schuster Rearrangement
  71. Handbook of Synthetic Photochemistry
  72. ChemInform Abstract: Heteroaromatic Trapping of Tricyclic 2‐Oxidocyclopentenyl Cations: A Surprisingly Efficient Example of Intermolecular Interrupted Nazarov Reaction.
  73. Silver(I)‐Mediated Electrocyclic Processes
  74. Brønsted Acid-Mediated Nazarov Cyclization of Vinylallenes
  75. Heteroaromatic Trapping of Tricyclic 2-Oxidocyclopentenyl Cations: A Surprisingly Efficient Example of Intermolecular Interrupted Nazarov Reaction
  76. ChemInform Abstract: Interrupting the Nazarov Reaction: Domino and Cascade Processes Utilizing Cyclopentenyl Cations
  77. The Photochemistry of Dienes and Polyenes: Application to the Synthesis of Complex Molecules
  78. Synthesis and characterization of 6-deoxy-6-fluoro-d-fructose as a potential compound for imaging breast cancer with PET
  79. Cyclization of Cross-Conjugated Trienes: The Vinylogous Nazarov Reaction
  80. Fused ring systems derived from reactions of half-open titanocenes with diynes: Syntheses, characterization, cage rearrangements, and structural studies
  81. One-Carbon Ring Expansion of Azetidines via Ammonium Ylide [1,2]-Shifts: A Simple Route to Substituted Pyrrolidines
  82. Diastereocontrol in [4+4]-photocycloadditions of pyran-2-ones: effect of ring substituents and chiral ketal
  83. Interrupting the Nazarov reaction: domino and cascade processes utilizing cyclopentenyl cations
  84. Ring Expansion of Lactones and Lactams via Propiolate 1-Carbon Intercalation
  85. Concise Route to Triquinanes from Pyran-2-ones
  86. ChemInform Abstract: Survey of Chemical Synthesis of the Pyrrolizidine Alkaloids Turneforcidine and Platynecine
  87. Cyclooctatrienes from pyran-2-ones via a tandem [4 + 4]-photocycloaddition/decarboxylation process
  88. Construction of aryl-substituted triquinanes through the interrupted Nazarov reaction
  89. Domino Electrocyclization/Azide-Capture/Schmidt Rearrangement of Dienones:  One-Step Synthesis of Dihydropyridones from Simple Building Blocks
  90. Interrupted Nazarov Reactions Using Dichlorocyclopropanes:  A Novel Mode of Arene Trapping
  91. Efficient intermolecular 3+2 trapping of the Nazarov intermediate with vinyl sulfides
  92. Highly Stereoselective 6π Electrocyclization of Bridged Bicyclic 1,3,5-Trienes
  93. Intramolecular Azide Trapping of the Nazarov Intermediate:  Formation of Peroxy-Bridged Indolizidinones via a Deep-Seated Rearrangement and Aerobic Oxidation
  94. Survey of Chemical Syntheses of the Pyrrolizidine Alkaloids Turneforcidine and Platynecine
  95. Polycyclic oxonium ylides — Use of cyclic acetals as convenient scaffolds in the construction of fused bicyclic compounds containing a medium ring
  96. [1,2]- or [2,3]-Rearrangement of Onium Ylides of Allyl and Benzyl Ethers and Sulfides via in Situ-Generated Iodonium Ylides
  97. Recent Advances in the Stevens Rearrangement of Ammonium Ylides. Application to the Synthesis of Alkaloid Natural Products
  98. Diastereoselective [4 + 4]-Photocycloaddition Reactions of Pyran-2-ones:  Rapid Access to Functionalized 5−8−5 Skeletons
  99. A New Approach to the Nazarov Reaction via Sequential Electrocyclic Ring Opening and Ring Closure
  100. Recent advances in the Stevens rearrangement of ammonium ylides. Application to the synthesis of alkaloid natural products
  101. Construction of fused bis(pyran) units from enones via a hydrosilylation–dihydroxylation–acetalization–reduction sequence
  102. Unexpected Participation of an Unconjugated Olefin during Nazarov Cyclization of Bridged Bicyclic Dienones
  103. Halide trapping of the Nazarov intermediate in strained polycyclic systems: a new interrupted Nazarov reaction
  104. Ring Expansion of Azetidinium Ylides:  Rapid Access to the Pyrrolizidine Alkaloids Turneforcidine and Platynecine
  105. Stereoselective Nazarov Cyclizations of Bridged Bicyclic Dienones
  106. Hydrazulene Ring Systems via Heteroatom-Assisted [1,2]-Shift of Oxonium and Sulfonium Ylides
  107. Rearrangement Processes of Oxonium and Ammonium Ylides Formed by Rhodium(II)‐Catalyzed Carbene Transfer
  108. Solvent Trapping of Photochemically Generated Pyran-4-one-Derived Oxyallyls: A Convenient Cyclopentannulation Method
  109. A Convenient Method for the Synthesis of Terminal (E)-1,3-Dienes
  110. Convenient route to centro-substituted triquinacene skeletons via the interrupted Nazarov reaction
  111. Ammonium, Oxonium and Sulfonium Ylides—Generation of Ammonium Ylides from Metal Carbenoids
  112. Photochemical Rearrangement and Trapping Reactions of 4‐Pyrones
  113. Catalyst and Ring Size Effects on Periselectivity of Oxonium Ylide Rearrangements
  114. Efficient construction of benzohydrindenones from aryltrienones via domino Nazarov electrocyclization – electrophilic aromatic substitution
  115. Improved Yields with Added Copper(I) Salts in Carbonylative Stille Couplings of Sterically Hindered Vinylstannanes
  116. Cyclooctanoid Ring Systems from Mixed Acetals via Heteroatom-Assisted [1,2]-Shift of Oxonium Ylides
  117. Photochemical Rearrangement and Trapping Reactions of 4-Pyrones
  118. Formal Intermolecular 4 + 4 Approach to Cyclooctanoids:  4 + 3 Capture of the Nazarov Oxyallyl Intermediate with Simple 1,3-Dienes
  119. Stereoselective formation and rearrangement of morpholinium ylides derived from copper carbenoids
  120. New Efficient Iterative Approaches to Polycyclic Ethers
  121. New Efficient Iterative Approaches to Polycyclic Ethers
  122. A Novel, Stereoselective Silyl-Directed Stevens [1,2]-Shift of Ammonium Ylides
  123. Equilibrium and Kinetic Analyses of the Interactions between Vitamin B12 Binding Proteins and Cobalamins by Surface Plasmon Resonance
  124. Cyclic oxonium ylides: building blocks for iterative synthesis of polycyclic ethers
  125. ChemInform Abstract: Solvent Trapping of Photochemically Generated Pyran‐4‐one‐Derived Oxyallyls: A Convenient Cyclopentannulation Method.
  126. Highly Efficient Trapping of the Nazarov Intermediate with Substituted Arenes
  127. Iterative Approach to Polycyclic Ethers Based on Stereoselective Oxonium Ylide [2,3]-Shifts
  128. Lithium Hydroperoxide
  129. Synthesis and Characterization of Fluorescent Cobalamin (CobalaFluor) Derivatives for Imaging
  130. 10-Deacetyl baccatin III dimethyl sulfoxide disolvate
  131. Ionic Hydrogenation of Oxyallyl Intermediates: The Reductive Nazarov Cyclization
  132. ChemInform Abstract: Intermolecular Trapping of the Nazarov Intermediate: Domino Electrocyclization/[3 + 2] Cycloadditions with Allylsilanes.
  133. Intermolecular Trapping of the Nazarov Intermediate: Domino Electrocyclization/[3+2] Cycloadditions with Allylsilanes
  134. Coumarin derivatives and breast-feeding
  135. Synthesis, characterization, and organic chemistry of an edge-bridged half-open titanocene
  136. Formation of Hydrindans and Tricyclo[4.3.0.03,8]nonanes via 6-Endo Trapping of the Nazarov Oxyallyl Intermediate
  137. Nazarov-Initiated Diastereoselective Cascade Polycyclization of Aryltrienones1
  138. Chirality Transfer from Carbon to Nitrogen to Carbon via Cyclic Ammonium Ylides
  139. Synthesis of Bridged Bicyclic Ethers and Fused Oxetanes from Pyran-4-ones via Tandem Solvent Trapping and Norrish Type II Cyclization1
  140. A Novel Cycloisomerization of Tetraenones:  4+3 Trapping of the Nazarov Oxyallyl Intermediate
  141. The reductive Nazarov cyclization
  142. Medium ring ethers via [1,2]-shift of acetal-derived oxonium ylides
  143. 1,3-Dioxolan-2-ylium cations from acylfurans: Conversion of furyl ketones to esters under nonoxidative conditions
  144. Highly Diastereoselective Cycloisomerization of Acyclic Trienones. The Interrupted Nazarov Reaction
  145. A short, enantioselective synthesis of (−)-epilupinine from proline via a spirocyclic ammonium ylide
  146. Sonolysis Promotes Indirect Co−C Bond Cleavage of Alkylcob(III)alamin Bioconjugates
  147. The Photochemistry of Dienes and Polyenes: Application to the Synthesis of Complex Molecules
  148. Tandem Enamine Michael Additions to 4-(Mesyloxy)cyclopentenones:  Bridged Tricyclic Skeletons via a Net [3 + 2] Construction1
  149. Photocyclization and photocycloaddition reactions of 4- and 2-pyrones
  150. Efficient Construction of Bi- and Tricyclic Cyclooctanoid Systems via Crossed [4+4]-Photocycloadditions of Pyran-2-ones1
  151. The Total Synthesis of a Natural Cardenolide:  (+)-Digitoxigenin
  152. Unexpected and efficient photochemical rearrangement of 6-hydroxyethylpyran-2-ones to 4-AIkylidene-5,6-dihydropyrans
  153. Unprecedented Diastereoselective Addition Reactions of 6,6-Dimethylcyclohexadienyl Titanium Complexes to Aldehydes and Ketones
  154. Intramolecular carboxylic acid trapping of pyran-4-one derived zwitterions: A novel synthesis of fused bicyclic lactones
  155. Profound Catalyst Effects in the Generation and Reactivity of Carbenoid-Derived Cyclic Ylides
  156. Applications of Stevens [1,2]-Shifts of Cyclic Ammonium Ylides. A Route to Morpholin-2-ones
  157. Piperidines via Ammonium Ylide [1,2]-Shifts: A Concise, Enantioselective Route to (-)-Epilupinine from Proline Ester
  158. Intramolecular [4 + 3]-cycloadditions of photochemically generated oxyallyl zwitterions: a route to functionalized cyclooctanoid skeletons
  159. Photochemical ring-contraction of fused bicyclic 4-pyrones: A novel 2-step cyclopentannulation approach
  160. Pseudocine substitution via internal delivery. Formal cyclopentadienone-ketone Michael adducts from 4-hydroxycyclopentenones
  161. Intramolecular arene trapping of pyran-4-one derived zwitterions: a two-step synthesis of tetrahydrobenz[e]inden-1-ones
  162. Intramolecular [4+4]-photocycloadditions of 2-pyrones: an efficient approach to cyclooctanoid construction
  163. Pseudocine substitution of 4-(mesyloxy)-2-cyclopentenones: an efficient route to 2,4-disubstituted 2-cyclopentenones
  164. Intramolecular alkene trapping of pyran-4-one-derived Zwitterions: a novel synthesis of diquinanes and hydrindans
  165. New route to substituted piperidines via the Stevens [1,2]-shift of ammonium ylides
  166. O-Bridged medium sized rings via bicyclic oxonium ylides
  167. Novel bicyclic oxazolines via nitrile capture of photochemically generated oxyallyl zwitterions
  168. One-Step Synthesis of Tertiary α-Amino Ketones and α-Amino Esters From Amines and Diazocarbonyl Compounds
  169. The Stevens [1,2]-shift of oxonium ylides: a route to substituted tetrahydrofuranones
  170. The photochemistry of pyran-4-ones: intramolecular trapping of the zwitterionic intermediate with pendant hydroxyl groups
  171. Ylides by the desilylation of .alpha.-silyl onium salts
  172. Nonstabilized imidate ylides by the desilylation method: a route to the pyrrolizidine alkaloids retronecine and indicine
  173. Thioimidate methylides by the desilylation method: an improved synthesis of pyrrolines and pyrroles