All Stories

  1. A cationic single-chain bolalipid forms stable vesicles with distinct interfacial behavior
  2. Liposomal Delivery of Pyronaridine as a Repurposed Inhibitor of ERCC1/XPF for the Sensitization of Colorectal Cancer Cells to Platinum Chemotherapeutics
  3. Regioselective Introduction of Indolin-3-one Moieties to Substituted Heteroaromatic Compounds
  4. Cover Feature: Copper‐Catalyzed Synthesis of C‐2 Substituted Indolin‐3‐Ones and Indolin‐3‐One [4+2] Cycloadducts Through Azide‐Tethered Iodonium Ylides (Asian J. Org. Chem. 5/2025)
  5. Copper‐Catalyzed Synthesis of C‐2 Substituted Indolin‐3‐Ones and Indolin‐3‐One [4+2] Cycloadducts Through Azide‐Tethered Iodonium Ylides
  6. Structure-Based Discovery of Allosteric Inhibitors Targeting a New Druggable Site in the Respiratory Syncytial Virus Polymerase
  7. Proof of concept: Pull down assay using bovine serum albumin and an immunomodulator small molecule
  8. Stereoselective Intramolecular [2+2] Trapping of 1,2‐Cyclohexadienes: a Route to Rigid, Angularly Fused Tricyclic Scaffolds
  9. 2 + 2 Trapping of Acyloxy-1,2-cyclohexadienes with Styrenes and Electron-Deficient Olefins
  10. Repurposing Antimalarial Pyronaridine as a DNA Repair Inhibitor to Exploit the Full Potential of Gold-Nanoparticle-Mediated Radiation Response
  11. PET Imaging of Fructose Metabolism in a Rodent Model of Neuroinflammation with 6-[18F]fluoro-6-deoxy-D-fructose
  12. A Fluorescence-Based Assay to Probe Inhibitory Effect of Fructose Mimics on GLUT5 Transport in Breast Cancer Cells
  13. Towards Selective Binding to the GLUT5 Transporter: Synthesis, Molecular Dynamics and In Vitro Evaluation of Novel C-3-Modified 2,5-Anhydro-D-mannitol Analogs
  14. Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition
  15. Cover Feature: Lithium Hydroxide Assisted Endo ‐Selective [4+4]‐Photocycloaddition of Pyran‐2‐ones (Eur. J. Org. Chem. 16/2021)
  16. Lithium Hydroxide Assisted Endo ‐Selective [4+4]‐Photocycloaddition of Pyran‐2‐ones
  17. Pharmacological targets and emerging treatments for respiratory syncytial virus bronchiolitis
  18. Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1–XPF-mediated DNA repair
  19. Design, synthesis, and evaluation of positron emission tomography/fluorescence dual imaging probes for targeting facilitated glucose transporter 1 (GLUT1)
  20. Generation and trapping of electron-deficient 1,2-cyclohexadienes. Unexpected hetero-Diels–Alder reactivity
  21. Design, synthesis and in vitro cell-free/cell-based biological evaluations of novel ERCC1-XPF inhibitors targeting DNA repair pathway
  22. A Mild Method for the Generation and Interception of 1,2-Cycloheptadienes with 1,3-Dipoles
  23. Computer‐aided drug design of small molecule inhibitors of the ERCC1‐XPF protein–protein interaction
  24. Comprehensive in vitro characterization of PD-L1 small molecule inhibitors
  25. Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1–XPF
  26. Strain-Activated Diels–Alder Trapping of 1,2-Cyclohexadienes: Intramolecular Capture by Pendent Furans
  27. Asymmetric synthesis of (+)-laurencin using a stereoselective Stevens [1,2]-shift of a sulfonium ylide
  28. The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C
  29. Dual Catalytic Synthesis of Antiviral Compounds Based on Metallocarbene–Azide Cascade Chemistry
  30. One-Pot Generation of Bicyclo[3.1.0]hexanols and Cyclohexanones by Double Interrupted Nazarov Reactions
  31. Molecular Imaging of GLUT1 and GLUT5 in Breast Cancer: A Multitracer Positron Emission Tomography Imaging Study in Mice
  32. Synthesis and biological evaluation of structurally simplified noscapine analogues as microtubule binding agents
  33. Tunable GLUT-Hexose Binding and Transport via Modulation of Hexose C-3 Hydrogen-Bonding Capabilities
  34. Intercepting the Nazarov Oxyallyl Intermediate with α-Formyl­vinyl Anion Equivalents to Access Formal Morita–Baylis–Hillman Alkylation Products
  35. Oxidation‐Initiated Cyclizations of Pentadienyl Ethers: An Alternative Entry to the Nazarov Reaction
  36. Oxidation‐Initiated Cyclizations of Pentadienyl Ethers: An Alternative Entry to the Nazarov Reaction
  37. Fluorescent Hexose Conjugates Establish Stringent Stereochemical Requirement by GLUT5 for Recognition and Transport of Monosaccharides
  38. Medium-Sized Cyclic Ethers via Stevens [1,2]-Shift of Mixed Monothioacetal-Derived Sulfonium Ylides: Application to Formal Synthesis of (+)-Laurencin
  39. Evidence for heterolytic cleavage of a cyclic oxonium ylide: implications for the mechanism of the Stevens [1,2]-shift
  40. Interrupting the Nazarov Cyclization with Bromine
  41. Structures reveal details of small molecule binding to cardiac troponin
  42. Efficient Trapping of 1,2-Cyclohexadienes with 1,3-Dipoles
  43. A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation
  44. Efficient and Easy Access to Optically Pure Tetrasubstituted Tetra­hydrofurans via Stereoselective Opening ofC2-Symmetric Epoxide and Aziridine Rings
  45. 1,4‐Diketones from Cross‐Conjugated Dienones: Potassium Permanganate‐Interrupted Nazarov Reaction
  46. Diastereoselective N-quaternization of piperidines
  47. Reactivity and Stereoselectivity of 6π and Nazarov Electrocyclizations of Bridged Bicyclic Trienes and Divinyl Ketones
  48. New fluorinated fructose analogs as selective probes of the hexose transporter protein GLUT5
  49. Correction: New fluorinated fructose analogs as selective probes of the hexose transporter protein GLUT5
  50. Experimental and Computational Studies on Interrupted Nazarov Reactions: Exploration of Umpolung Reactivity at the α-Carbon of Cyclopentanones
  51. Formal Homologous Aldol Reactions: Interrupting the Nazarov Cyclization via Carboalkoxylation of Alkynes
  52. Ready Access to Alkylidenecyclopentenones by Nazarov Cyclization/β-Elimination of 2-Hydroxyalkyl-1,4-dien-3-ones
  53. α-Hydroxycyclopentanones via one-pot oxidation of the trimethylaluminum-mediated Nazarov reaction with triplet oxygen
  54. Azide trapping of metallocarbenes: generation of reactive C-acylimines and domino trapping with nucleophiles
  55. Efficient synthesis of bicyclo[6.3.0]undecadienones by Nazarov cyclization/regioselective elimination
  56. ChemInform Abstract: Organoaluminum‐Mediated Interrupted Nazarov Reaction.
  57. Hydroxylic additives enhance yield and scalability of silicon-directed Nazarov reaction
  58. Organoaluminum‐Mediated Interrupted Nazarov Reaction
  59. Organoaluminum‐Mediated Interrupted Nazarov Reaction
  60. Nazarov Reactions of Vinyl Cyclopropylamines: An Approach to the Imino-Nazarov Problem
  61. Intramolecular generation and rearrangement of oxonium ylides: methodology studies and their application in synthesis
  62. Prion inhibition with multivalent PrPSc binding compounds
  63. Regioselective synthesis of 2-iminooxazinones from dioxinones and carbodiimides
  64. Superacid-catalyzed Friedel–Crafts cyclization of unactivated alkenes
  65. Lithium Hydroperoxide
  66. Construction of α-amido-indanones via formal allenamide hydroacylation–Nazarov cyclization
  67. Preparation and Synthetic Applications of Azetidines
  68. Homologous Mukaiyama Reactions via Trapping of the Nazarov Intermediate with Silyloxyalkenes
  69. Radiopharmacological evaluation of 6-deoxy-6-[18F]fluoro-d-fructose as a radiotracer for PET imaging of GLUT5 in breast cancer
  70. Expedient Route to the Tigliane-Daphnane Skeleton via Oxonium Ylide [1,2]-Shift
  71. Intermolecular [3 + 3]-Cycloadditions of Azides with the Nazarov Intermediate
  72. Olefination of α,α′-Divinyl Ketones through Catalytic Meyer−Schuster Rearrangement
  73. Handbook of Synthetic Photochemistry
  74. ChemInform Abstract: Heteroaromatic Trapping of Tricyclic 2‐Oxidocyclopentenyl Cations: A Surprisingly Efficient Example of Intermolecular Interrupted Nazarov Reaction.
  75. Silver(I)‐Mediated Electrocyclic Processes
  76. Brønsted Acid-Mediated Nazarov Cyclization of Vinylallenes
  77. Heteroaromatic Trapping of Tricyclic 2-Oxidocyclopentenyl Cations: A Surprisingly Efficient Example of Intermolecular Interrupted Nazarov Reaction
  78. ChemInform Abstract: Interrupting the Nazarov Reaction: Domino and Cascade Processes Utilizing Cyclopentenyl Cations
  79. The Photochemistry of Dienes and Polyenes: Application to the Synthesis of Complex Molecules
  80. Synthesis and characterization of 6-deoxy-6-fluoro-d-fructose as a potential compound for imaging breast cancer with PET
  81. Cyclization of Cross-Conjugated Trienes: The Vinylogous Nazarov Reaction
  82. Fused ring systems derived from reactions of half-open titanocenes with diynes: Syntheses, characterization, cage rearrangements, and structural studies
  83. One-Carbon Ring Expansion of Azetidines via Ammonium Ylide [1,2]-Shifts: A Simple Route to Substituted Pyrrolidines
  84. Diastereocontrol in [4+4]-photocycloadditions of pyran-2-ones: effect of ring substituents and chiral ketal
  85. Interrupting the Nazarov reaction: domino and cascade processes utilizing cyclopentenyl cations
  86. Ring Expansion of Lactones and Lactams via Propiolate 1-Carbon Intercalation
  87. Concise Route to Triquinanes from Pyran-2-ones
  88. ChemInform Abstract: Survey of Chemical Synthesis of the Pyrrolizidine Alkaloids Turneforcidine and Platynecine
  89. Cyclooctatrienes from pyran-2-ones via a tandem [4 + 4]-photocycloaddition/decarboxylation process
  90. Construction of aryl-substituted triquinanes through the interrupted Nazarov reaction
  91. Domino Electrocyclization/Azide-Capture/Schmidt Rearrangement of Dienones:  One-Step Synthesis of Dihydropyridones from Simple Building Blocks
  92. Interrupted Nazarov Reactions Using Dichlorocyclopropanes:  A Novel Mode of Arene Trapping
  93. Efficient intermolecular 3+2 trapping of the Nazarov intermediate with vinyl sulfides
  94. Highly Stereoselective 6π Electrocyclization of Bridged Bicyclic 1,3,5-Trienes
  95. Intramolecular Azide Trapping of the Nazarov Intermediate:  Formation of Peroxy-Bridged Indolizidinones via a Deep-Seated Rearrangement and Aerobic Oxidation
  96. Survey of Chemical Syntheses of the Pyrrolizidine Alkaloids Turneforcidine and Platynecine
  97. Polycyclic oxonium ylides — Use of cyclic acetals as convenient scaffolds in the construction of fused bicyclic compounds containing a medium ring
  98. [1,2]- or [2,3]-Rearrangement of Onium Ylides of Allyl and Benzyl Ethers and Sulfides via in Situ-Generated Iodonium Ylides
  99. Recent Advances in the Stevens Rearrangement of Ammonium Ylides. Application to the Synthesis of Alkaloid Natural Products
  100. Diastereoselective [4 + 4]-Photocycloaddition Reactions of Pyran-2-ones:  Rapid Access to Functionalized 5−8−5 Skeletons
  101. A New Approach to the Nazarov Reaction via Sequential Electrocyclic Ring Opening and Ring Closure
  102. Recent advances in the Stevens rearrangement of ammonium ylides. Application to the synthesis of alkaloid natural products
  103. Construction of fused bis(pyran) units from enones via a hydrosilylation–dihydroxylation–acetalization–reduction sequence
  104. Unexpected Participation of an Unconjugated Olefin during Nazarov Cyclization of Bridged Bicyclic Dienones
  105. Halide trapping of the Nazarov intermediate in strained polycyclic systems: a new interrupted Nazarov reaction
  106. Ring Expansion of Azetidinium Ylides:  Rapid Access to the Pyrrolizidine Alkaloids Turneforcidine and Platynecine
  107. Stereoselective Nazarov Cyclizations of Bridged Bicyclic Dienones
  108. Hydrazulene Ring Systems via Heteroatom-Assisted [1,2]-Shift of Oxonium and Sulfonium Ylides
  109. Rearrangement Processes of Oxonium and Ammonium Ylides Formed by Rhodium(II)‐Catalyzed Carbene Transfer
  110. Solvent Trapping of Photochemically Generated Pyran-4-one-Derived Oxyallyls: A Convenient Cyclopentannulation Method
  111. A Convenient Method for the Synthesis of Terminal (E)-1,3-Dienes
  112. Convenient route to centro-substituted triquinacene skeletons via the interrupted Nazarov reaction
  113. Ammonium, Oxonium and Sulfonium Ylides—Generation of Ammonium Ylides from Metal Carbenoids
  114. Photochemical Rearrangement and Trapping Reactions of 4‐Pyrones
  115. Catalyst and Ring Size Effects on Periselectivity of Oxonium Ylide Rearrangements
  116. Efficient construction of benzohydrindenones from aryltrienones via domino Nazarov electrocyclization – electrophilic aromatic substitution
  117. Improved Yields with Added Copper(I) Salts in Carbonylative Stille Couplings of Sterically Hindered Vinylstannanes
  118. Cyclooctanoid Ring Systems from Mixed Acetals via Heteroatom-Assisted [1,2]-Shift of Oxonium Ylides
  119. Photochemical Rearrangement and Trapping Reactions of 4-Pyrones
  120. Formal Intermolecular 4 + 4 Approach to Cyclooctanoids:  4 + 3 Capture of the Nazarov Oxyallyl Intermediate with Simple 1,3-Dienes
  121. Stereoselective formation and rearrangement of morpholinium ylides derived from copper carbenoids
  122. New Efficient Iterative Approaches to Polycyclic Ethers
  123. New Efficient Iterative Approaches to Polycyclic Ethers
  124. A Novel, Stereoselective Silyl-Directed Stevens [1,2]-Shift of Ammonium Ylides
  125. Equilibrium and Kinetic Analyses of the Interactions between Vitamin B12 Binding Proteins and Cobalamins by Surface Plasmon Resonance
  126. Cyclic oxonium ylides: building blocks for iterative synthesis of polycyclic ethers
  127. ChemInform Abstract: Solvent Trapping of Photochemically Generated Pyran‐4‐one‐Derived Oxyallyls: A Convenient Cyclopentannulation Method.
  128. Highly Efficient Trapping of the Nazarov Intermediate with Substituted Arenes
  129. Iterative Approach to Polycyclic Ethers Based on Stereoselective Oxonium Ylide [2,3]-Shifts
  130. Lithium Hydroperoxide
  131. Synthesis and Characterization of Fluorescent Cobalamin (CobalaFluor) Derivatives for Imaging
  132. 10-Deacetyl baccatin III dimethyl sulfoxide disolvate
  133. Ionic Hydrogenation of Oxyallyl Intermediates: The Reductive Nazarov Cyclization
  134. ChemInform Abstract: Intermolecular Trapping of the Nazarov Intermediate: Domino Electrocyclization/[3 + 2] Cycloadditions with Allylsilanes.
  135. Intermolecular Trapping of the Nazarov Intermediate: Domino Electrocyclization/[3+2] Cycloadditions with Allylsilanes
  136. Coumarin derivatives and breast-feeding
  137. Synthesis, characterization, and organic chemistry of an edge-bridged half-open titanocene
  138. Formation of Hydrindans and Tricyclo[4.3.0.03,8]nonanes via 6-Endo Trapping of the Nazarov Oxyallyl Intermediate
  139. Nazarov-Initiated Diastereoselective Cascade Polycyclization of Aryltrienones1
  140. Chirality Transfer from Carbon to Nitrogen to Carbon via Cyclic Ammonium Ylides
  141. Synthesis of Bridged Bicyclic Ethers and Fused Oxetanes from Pyran-4-ones via Tandem Solvent Trapping and Norrish Type II Cyclization1
  142. A Novel Cycloisomerization of Tetraenones:  4+3 Trapping of the Nazarov Oxyallyl Intermediate
  143. The reductive Nazarov cyclization
  144. Medium ring ethers via [1,2]-shift of acetal-derived oxonium ylides
  145. 1,3-Dioxolan-2-ylium cations from acylfurans: Conversion of furyl ketones to esters under nonoxidative conditions
  146. Highly Diastereoselective Cycloisomerization of Acyclic Trienones. The Interrupted Nazarov Reaction
  147. A short, enantioselective synthesis of (−)-epilupinine from proline via a spirocyclic ammonium ylide
  148. Sonolysis Promotes Indirect Co−C Bond Cleavage of Alkylcob(III)alamin Bioconjugates
  149. The Photochemistry of Dienes and Polyenes: Application to the Synthesis of Complex Molecules
  150. Tandem Enamine Michael Additions to 4-(Mesyloxy)cyclopentenones:  Bridged Tricyclic Skeletons via a Net [3 + 2] Construction1
  151. Photocyclization and photocycloaddition reactions of 4- and 2-pyrones
  152. Efficient Construction of Bi- and Tricyclic Cyclooctanoid Systems via Crossed [4+4]-Photocycloadditions of Pyran-2-ones1
  153. The Total Synthesis of a Natural Cardenolide:  (+)-Digitoxigenin
  154. Unexpected and efficient photochemical rearrangement of 6-hydroxyethylpyran-2-ones to 4-AIkylidene-5,6-dihydropyrans
  155. Unprecedented Diastereoselective Addition Reactions of 6,6-Dimethylcyclohexadienyl Titanium Complexes to Aldehydes and Ketones
  156. Intramolecular carboxylic acid trapping of pyran-4-one derived zwitterions: A novel synthesis of fused bicyclic lactones
  157. Profound Catalyst Effects in the Generation and Reactivity of Carbenoid-Derived Cyclic Ylides
  158. Applications of Stevens [1,2]-Shifts of Cyclic Ammonium Ylides. A Route to Morpholin-2-ones
  159. Piperidines via Ammonium Ylide [1,2]-Shifts: A Concise, Enantioselective Route to (-)-Epilupinine from Proline Ester
  160. Intramolecular [4 + 3]-cycloadditions of photochemically generated oxyallyl zwitterions: a route to functionalized cyclooctanoid skeletons
  161. Photochemical ring-contraction of fused bicyclic 4-pyrones: A novel 2-step cyclopentannulation approach
  162. Pseudocine substitution via internal delivery. Formal cyclopentadienone-ketone Michael adducts from 4-hydroxycyclopentenones
  163. Intramolecular arene trapping of pyran-4-one derived zwitterions: a two-step synthesis of tetrahydrobenz[e]inden-1-ones
  164. Intramolecular [4+4]-photocycloadditions of 2-pyrones: an efficient approach to cyclooctanoid construction
  165. Pseudocine substitution of 4-(mesyloxy)-2-cyclopentenones: an efficient route to 2,4-disubstituted 2-cyclopentenones
  166. Intramolecular alkene trapping of pyran-4-one-derived Zwitterions: a novel synthesis of diquinanes and hydrindans
  167. New route to substituted piperidines via the Stevens [1,2]-shift of ammonium ylides
  168. O-Bridged medium sized rings via bicyclic oxonium ylides
  169. Novel bicyclic oxazolines via nitrile capture of photochemically generated oxyallyl zwitterions
  170. One-Step Synthesis of Tertiary α-Amino Ketones and α-Amino Esters From Amines and Diazocarbonyl Compounds
  171. The Stevens [1,2]-shift of oxonium ylides: a route to substituted tetrahydrofuranones
  172. The photochemistry of pyran-4-ones: intramolecular trapping of the zwitterionic intermediate with pendant hydroxyl groups
  173. Ylides by the desilylation of .alpha.-silyl onium salts
  174. Nonstabilized imidate ylides by the desilylation method: a route to the pyrrolizidine alkaloids retronecine and indicine
  175. Thioimidate methylides by the desilylation method: an improved synthesis of pyrrolines and pyrroles