All Stories

  1. Microemulsion-Inspired Polysaccharide Nanoparticles for an Advanced Targeted Thrombolytic Treatment

    Article • ACS Nano, January 2025, American Chemical Society (ACS)

    Professor Frederic Chaubet

  2. Hyaluronic acid from bluefin tuna by-product: Structural analysis and pharmacological activities

    Article • International Journal of Biological Macromolecules, April 2024, Elsevier

    Professor Frederic Chaubet

  3. Comparative Analysis of Physicochemical Characteristics of Chondroitin Sulfate from Avian Cartilage: Antioxidant, Anti-inflammatory and Anti-nociceptive Properties

    Article • Chemistry Africa, November 2023, Springer Science + Business Media

    Professor Frederic Chaubet

  4. Fucoidan-coated coils improve healing in a rabbit elastase aneurysm model

    Article • Journal of NeuroInterventional Surgery, July 2023, BMJ

    Professor Frederic Chaubet

  5. Optical and X-ray attenuation properties of hafnium oxide nanoparticles surface functionalized with fucoidan: toward the early diagnosis of atherothrombotic diseases

    Article • Materials Advances, January 2023, Royal Society of Chemistry

    Professor Frederic Chaubet

  6. Spatial-Controlled Coating of Pro-Angiogenic Proteins on 3D Porous Hydrogels Guides Endothelial Cell Behavior

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Professor Frederic Chaubet

  7. Iron Oxide Nanoparticles Functionalized with Fucoidan: a Potential Theranostic Nanotool for Hepatocellular Carcinoma

    Article • ChemBioChem, July 2022, Wiley

    Professor Frederic Chaubet

  8. miRNA Delivery by Nanosystems: State of the Art and Perspectives

    Article • Pharmaceutics, November 2021, MDPI AG

    Professor Frederic Chaubet

  9. Fucoidan-functionalized polysaccharide submicroparticles loaded with alteplase for efficient targeted thrombolytic therapy

    Article • Biomaterials, October 2021, Elsevier

    Professor Frederic Chaubet

  10. Characterization of dextran particle size: How frit-inlet asymmetrical flow field-flow fractionation (FI-AF4) coupled online with dynamic light scattering (DLS) leads to enhanced size distribution

    Article • Journal of Chromatography A, September 2021, Elsevier

    Professor Frederic Chaubet

  11. Bioactive refinement for endosaccular treatment of intracranial aneurysms

    Article • The Neuroradiology Journal, July 2021, SAGE Publications

    Professor Frederic Chaubet

  12. P-selectin targeting polysaccharide-based nanogels for miRNA delivery

    Article • International Journal of Pharmaceutics, March 2021, Elsevier

    Professor Frederic Chaubet

  13. Coronary stent CD31-mimetic coating favours endothelialization and reduces local inflammation and neointimal development in vivo

    Article • European Heart Journal, February 2021, Oxford University Press (OUP)

    Professor Frederic Chaubet

  14. Gd(DOTA)-grafted submicronic polysaccharide-based particles functionalized with fucoidan as potential MR contrast agent able to target human activated platelets

    Article • Carbohydrate Polymers, October 2020, Elsevier

    Professor Frederic Chaubet

  15. Anticoagulant activity of fucosylated chondroitin sulfate isolated from Cucumaria syracusana

    Article • Process Biochemistry, April 2020, Elsevier

    Professor Frederic Chaubet

  16. Synthesis of cationic quaternized pullulan derivatives for miRNA delivery

    Article • International Journal of Pharmaceutics, March 2020, Elsevier

    Professor Frederic Chaubet

  17. Pharmaceutical Development and Safety Evaluation of a GMP-Grade Fucoidan for Molecular Diagnosis of Cardiovascular Diseases

    Article • Marine Drugs, December 2019, MDPI AG

    Professor Frederic Chaubet

  18. Core-Shell Polymer-Based Nanoparticles Deliver miR-155-5p to Endothelial Cells

    Article • Molecular Therapy — Nucleic Acids, September 2019, Elsevier

    Professor Frederic Chaubet

  19. Early Detection of Localized Immunity in Experimental Autoimmune Myocarditis Using [99mTc]Fucoidan SPECT

    Article • Molecular Imaging and Biology, August 2019, Springer Science + Business Media

    Professor Frederic Chaubet

  20. Bimodal Fucoidan-Coated Zinc Oxide/Iron Oxide-Based Nanoparticles for the Imaging of Atherothrombosis

    Article • Molecules, March 2019, MDPI AG

    Professor Frederic Chaubet

  21. Pharmacology: Drug Delivery

    Article • January 2019, Elsevier

    Professor Frederic Chaubet

  22. Primary structure and anticoagulant activity of fucoidan from the sea cucumber Holothuria polii

    Article • International Journal of Biological Macromolecules, January 2019, Elsevier

    Professor Frederic Chaubet

  23. Thin films of binary amorphous Zn-Zr alloys developed by magnetron co-sputtering for the production of degradable coronary stents: A preliminary study

    Article • Bioactive Materials, December 2018, Elsevier

    Professor Frederic Chaubet

  24. Fucoidan/VEGF-based surface modification of decellularized pulmonary heart valve improves the antithrombotic and re-endothelialization potential of bioprostheses

    Article • Biomaterials, July 2018, Elsevier

    Professor Frederic Chaubet

  25. Amino-Fucoidan as a Vector for rtPA-Induced Fibrinolysis in Experimental Thrombotic Events

    Article • Thrombosis and Haemostasis, January 2018, Thieme Publishing Group

    Professor Frederic Chaubet

  26. Characterization and anticoagulant activity of a fucosylated chondroitin sulfate with unusually procoagulant effect from sea cucumber

    Article • Carbohydrate Polymers, October 2017, Elsevier

    Professor Frederic Chaubet

  27. Co-immobilization of chitosan and dermatan sulfate from Raja montagui skin on polyethylene terephthalate surfaces: Characterization and antibiofilm activity

    Article • International Journal of Polymeric Materials, July 2017, Taylor & Francis

    Professor Frederic Chaubet

  28. Gadolinium/terbium hybrid macromolecular complexes for bimodal imaging of atherothrombosis

    Article • Journal of Biomedical Optics, July 2017, SPIE

    Professor Frederic Chaubet

  29. Synthesis of nanoparticles based on PDMMLA derivative copolymers and study of warfarin encapsulation and controlled release

    Article • RSC Advances, January 2017, Royal Society of Chemistry

    Professor Frederic Chaubet

  30. Identification of a Pro-Angiogenic Potential and Cellular Uptake Mechanism of a LMW Highly Sulfated Fraction of Fucoidan from Ascophyllum nodosum

    Article • Marine Drugs, October 2016, MDPI AG

    Professor Frederic Chaubet

  31. Fucoidans in Nanomedicine

    Article • Marine Drugs, July 2016, MDPI AG

    Professor Frederic Chaubet

  32. In vitro and in vivo hemocompatibility evaluation of a new dermatan sulfate-modified PET patch for vascular repair surgery

    Article • Journal of Biomedical Materials Research Part B Applied Biomaterials, July 2016, Wiley

    Professor Frederic Chaubet

  33. Anti-thrombotic properties of a CD31-derived peptide coated on a surface

    Article • Frontiers in Bioengineering and Biotechnology, January 2016, Frontiers

    Professor Frederic Chaubet

  34. Polyester-based nanoparticles for the controlled release of bioactive coumarinic derivatives

    Article • Frontiers in Bioengineering and Biotechnology, January 2016, Frontiers

    Professor Frederic Chaubet

  35. Ultrasmall superparamagnetic iron oxide nanoparticles coated with fucoidan for molecular MRI of intraluminal thrombus

    Article • Nanomedicine, January 2015, Future Medicine

    Professor Frederic Chaubet

  36. Nanocrystals of Zn(Fe)O-based diluted magnetic semi-conductor as potential luminescent and magnetic bimodal bioimaging probes

    Article • RSC Advances, November 2014, Royal Society of Chemistry

    Professor Frederic Chaubet

  37. Purification of a Low Molecular Weight Fucoidan for SPECT Molecular Imaging of Myocardial Infarction

    Article • Marine Drugs, September 2014, MDPI AG

    Professor Frederic Chaubet, Dr Rana BEN AZZOUNA

  38. Synthesis and Biological Evaluation of New Bisphosphonate–Dextran Conjugates Targeting Breast Primary Tumor

    Article • Bioconjugate Chemistry, February 2014, American Chemical Society (ACS)

    Professor Frederic Chaubet

  39. Strong and specific interaction of ultra small superparamagnetic iron oxide nanoparticles and human activated platelets mediated by fucoidan coating

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Professor Frederic Chaubet

  40. Shape-memory starch for resorbable biomedical devices

    Article • Carbohydrate Polymers, January 2014, Elsevier

    Professor Frederic Chaubet

  41. A resorbable shape-memory starch-based stent for the treatment of salivary ducts under sialendoscopic surgery

    Article • The Laryngoscope, December 2013, Wiley

    Professor Frederic Chaubet

  42. Preparation of cytocompatible luminescent and magnetic nanohybrids based on ZnO, Zn0.95Ni0.05O and core@shell ZnO@Fe2O3 polymer grafted nanoparticles for biomedical imaging

    Article • Journal of Nanoparticle Research, November 2012, Springer Science + Business Media

    Professor Frederic Chaubet

  43. Molecular Imaging of Selectins in Endothelial Activation

    Article • Current Cardiovascular Imaging Reports, May 2012, Springer Science + Business Media

    Professor Frederic Chaubet, Dr Rana BEN AZZOUNA

  44. Pericardial Processing: Challenges, Outcomes and Future Prospects

    Article • September 2011, IntechOpen

    Professor Frederic Chaubet

  45. Radiolabeled Fucoidan as a P-Selectin Targeting Agent for In Vivo Imaging of Platelet-Rich Thrombus and Endothelial Activation

    Article • Journal of Nuclear Medicine, August 2011, Society of Nuclear Medicine

    Professor Frederic Chaubet

  46. Grafting of dermatan sulfate on polyethylene terephtalate to enhance biointegration

    Article • Journal of Biomedical Materials Research Part A, May 2011, Wiley

    Professor Frederic Chaubet

  47. In vivo targeted molecular imaging for activated platelets by mri using USPIO-fucoidan in rat abdominal aortic aneuryms model

    Article • Journal of Cardiovascular Magnetic Resonance, February 2011, Springer Science + Business Media

    Professor Frederic Chaubet

  48. Synthesis and evaluation of a tri-tyrosine decorated dextran MR contrast agent for vulnerable plaque detection

    Article • Chemical Communications, January 2011, Royal Society of Chemistry

    Professor Frederic Chaubet

  49. Anticoagulant activity of a dermatan sulfate from the skin of the shark Scyliorhinus canicula

    Article • Blood Coagulation & Fibrinolysis, September 2010, Wolters Kluwer Health

    Professor Frederic Chaubet

  50. Fabrication of porous polysaccharide-based scaffolds using a combined freeze-drying/cross-linking process

    Article • Acta Biomaterialia, September 2010, Elsevier

    Professor Frederic Chaubet

  51. Highly sulfated dermatan sulfate from the skin of the ray Raja montagui: anticoagulant activity and mechanism of action

    Article • Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, July 2010, Elsevier

    Professor Frederic Chaubet

  52. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, October 2009, Elsevier

    Professor Frederic Chaubet

  53. Tyrosine polyethylene glycol (PEG)-micelle magnetic resonance contrast agent for the detection of lipid rich areas in atherosclerotic plaque

    Article • Magnetic Resonance in Medicine, September 2009, Wiley

    Professor Frederic Chaubet

  54. Characterization of a novel dermatan sulfate with high antithrombin activity from ray skin (Raja radula)

    Article • Thrombosis Research, April 2009, Elsevier

    Professor Frederic Chaubet

  55. Mechanism of thrombin inhibition by heparin cofactor II and antithrombin in the presence of the ray (Raja radula) skin dermatan sulfate

    Article • Thrombosis Research, April 2009, Elsevier

    Professor Frederic Chaubet

  56. Biomimetic MRI Contrast Agent for Imaging of Inflammation in Atherosclerotic Plaque of ApoE−/− Mice

    Article • Investigative Radiology, March 2009, Wolters Kluwer Health

    Professor Frederic Chaubet

  57. A001 Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets

    Article • Archives of Cardiovascular Diseases, March 2009, Elsevier

    Professor Frederic Chaubet

  58. A002 A tyrosine PEG-micelle magnetic resonance contrast agent for the detection of lipid rich areas in the atherosclerotic plaque

    Article • Archives of Cardiovascular Diseases, March 2009, Elsevier

    Professor Frederic Chaubet

  59. Polysaccharides from the skin of the ray Raja radula. Partial characterization and anticoagulant activity

    Article • Thrombosis Research, February 2009, Elsevier

    Professor Frederic Chaubet

  60. Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, February 2009, Elsevier

    Professor Frederic Chaubet

  61. A Novel Cross-linked Poly(vinyl alcohol) (PVA) for Vascular Grafts

    Article • Advanced Functional Materials, October 2008, Wiley

    Professor Frederic Chaubet

  62. A new macromolecular paramagnetic MR contrast agent binds to activated human platelets

    Article • Contrast Media & Molecular Imaging, January 2007, Wiley

    Professor Frederic Chaubet

  63. Cationized pullulan 3D matrices as new materials for gene transfer

    Article • Journal of Biomedical Materials Research Part A, January 2007, Wiley

    Professor Frederic Chaubet

  64. The evaluation of a small-diameter polysaccharide-based arterial graft in rats

    Article • Biomaterials, November 2006, Elsevier

    Professor Frederic Chaubet

  65. CMR 2005: 4.03: A new contrast agent for magnetic resonance imaging of the vascular walls

    Article • Contrast Media & Molecular Imaging, January 2006, Wiley

    Professor Frederic Chaubet

  66. Bovine BMP osteoinductive potential enhanced by functionalized dextran-derived hydrogels

    Article • Biomaterials, August 2005, Elsevier

    Professor Frederic Chaubet

  67. Retention of transforming growth factor β1 using functionalized dextran-based hydrogels

    Article • Biomaterials, May 2005, Elsevier

    Professor Frederic Chaubet

  68. Poly(N-ethyl-4-vinylpyridinium) bromide as a potential probe to select heparin-like anticoagulant polyanions

    Article • Carbohydrate Polymers, January 2003, Elsevier

    Professor Frederic Chaubet

  69. Heparin‐like polymers modulate proinflammatory cytokine production by lipopolysaccharide‐stimulated human monocytes

    Article • Journal of Biomedical Materials Research, June 2002, Wiley

    Professor Frederic Chaubet

  70. Heparin-like polymers modulate proinflammatory cytokine production by lipopolysaccharide-stimulated human monocytes

    Article • Journal of Biomedical Materials Research, February 2002, Wiley

    Professor Frederic Chaubet

  71. Heparin and non-heparin-like dextrans differentially modulate endothelial cell proliferation:In vitroevaluation with soluble and crosslinked polysaccharide matrices

    Article • Journal of Biomedical Materials Research, January 2002, Wiley

    Professor Frederic Chaubet

  72. Interaction of specifically chemically modified dextrans with transforming growth factor β1: potentiation of its biological activity

    Article • Biochemical Pharmacology, January 2002, Elsevier

    Professor Frederic Chaubet

  73. Anticoagulant properties of dextranmethylcarboxylate benzylamide sulfate (DMCBSu); a new generation of bioactive functionalized dextran

    Article • Carbohydrate Research, May 2001, Elsevier

    Professor Frederic Chaubet

  74. Relationship between antithrombotic activities of fucans and their structure

    Article • Drug Development Research, December 2000, Wiley

    Professor Frederic Chaubet

  75. Relationships between chemical characteristics and anticoagulant activity of low molecular weight fucans from marine algae

    Article • January 2000, Springer Science + Business Media

    Professor Frederic Chaubet

  76. Low-molecular-weight dextran derivatives (f-CMDB) enter the nucleus and are better cell-growth inhibitors compared with parent CMDB polymers

    Article • Carbohydrate Research, December 1999, Elsevier

    Professor Frederic Chaubet

  77. Interpolyelectrolyte reactions in solutions of functionalized dextrans with negatively charged groups along the chains

    Article • Macromolecular Chemistry and Physics, July 1999, Wiley

    Professor Frederic Chaubet

  78. Interpolyelectrolyte reactions in solutions of functionalized dextrans with negatively charged groups along the chains

    Article • Macromolecular Chemistry and Physics, July 1999, Wiley

    Professor Frederic Chaubet

  79. Effects of the binding of a dextran derivative on fibroblast growth factor 2: secondary structure and receptor-binding studies

    Article • Biochemical Pharmacology, June 1999, Elsevier

    Professor Frederic Chaubet

  80. Further data on the structure of brown seaweed fucans: relationships with anticoagulant activity

    Article • Carbohydrate Research, June 1999, Elsevier

    Professor Frederic Chaubet

  81. Sulphated polysaccharides derived from dextran: biomaterials for vascular therapy

    Article • Polymer International, April 1999, Wiley

    Professor Frederic Chaubet

  82. Anticoagulant activity of dextran derivatives

    Article • Journal of Biomedical Materials Research, July 1998, Wiley

    Professor Frederic Chaubet

  83. Carboxymethylation of dextran in aqueous alcohol as the first step of the preparation of derivatized dextrans

    Article • Die Angewandte Makromolekulare Chemie, February 1998, Wiley

    Professor Frederic Chaubet

  84. Comparative anticoagulant activity and influence on thrombin generation of dextran derivatives and of a fucoidan fraction

    Article • Journal of Biomaterials Science Polymer Edition, January 1998, Taylor & Francis

    Professor Frederic Chaubet

  85. Anticoagulant activity of functionalized dextrans. Structure analyses of carboxymethylated dextran and first Monte Carlo simulations

    Article • Carbohydrate Polymers, May 1997, Elsevier

    Professor Frederic Chaubet

  86. New investigations on heparin-like derivatized dextrans: CMDBS, synergistic role of benzylamide and sulfate substituents in anticoagulant activity

    Article • Carbohydrate Polymers, February 1997, Elsevier

    Professor Frederic Chaubet

  87. Anticoagulant low molecular weight fucans produced by radical process and ion exchange chromatography of high molecular weight fucans extracted from the brown seaweed Ascophyllum nodosum

    Article • Carbohydrate Research, August 1996, Elsevier

    Professor Frederic Chaubet

  88. Relationships between chemical characteristics and anticomplementary activity of fucans

    Article • Biomaterials, March 1996, Elsevier

    Professor Frederic Chaubet

  89. Synthesis and structure—anticoagulant property relationships of functionalized dextrans: CMDBS

    Article • Carbohydrate Polymers, January 1995, Elsevier

    Professor Frederic Chaubet

  90. Synthèse et études structurales de nouveaux complexes polyhydroxamiques du fer(III) potentiellement utilisables en imagerie par résonance magnétique nucléaire.Deuxième partie: Études des complexes formés in situ à partir d'acides hydroxamiques. Relaxi...

    Article • Canadian Journal of Chemistry, December 1994, Canadian Science Publishing

    Professor Frederic Chaubet

  91. Synthèse et études structurales de nouveaux complexes polyhydroxamiques du fer(III) potentiellement utilisables en imagerie par résonance magnétique nucléaire. I: Obtention des ligands

    Article • Canadian Journal of Chemistry, July 1991, Canadian Science Publishing

    Professor Frederic Chaubet

  92. The design of magnetic resonance contrast agents: New iron (III) dihydroxamate complexes

    Article • Tetrahedron Letters, January 1990, Elsevier

    Professor Frederic Chaubet