All Stories

  1. Bridging the TB data gap: in silico extraction of rifampicin-resistant tuberculosis diagnostic test results from whole genome sequence data

    Article • PeerJ, August 2019, PeerJ

    Dr Frank van Leth

  2. Rethinking Antimicrobial Resistance Surveillance: A Role for Lot Quality Assurance Sampling

    Article • American Journal of Epidemiology, January 2019, Oxford University Press (OUP)

    Dr Frank van Leth, R. Lia Kusumawati

  3. The Tuberculosis Network European Trials group (TBnet) ERS Clinical Research Collaboration: addressing drug-resistant tuberculosis through European cooperation

    Article • European Respiratory Journal, January 2019, European Respiratory Society (ERS)

    Dr Frank van Leth

  4. Clinical Management of Multidrug-Resistant Tuberculosis in 16 European Countries

    Article • American Review of Respiratory Disease, August 2018, American Thoracic Society

    Dr Frank van Leth, Dr Valeriu Crudu

  5. Predictive value of the urinary dipstick test in the management of patients with urinary tract infection-associated symptoms in primary care in Indonesia: a cross-sectional study

    Article • BMJ Open, August 2018, BMJ

    Dr Frank van Leth, R. Lia Kusumawati

  6. Testing for LTBI: more of the same or a step forward?

    Article • The International Journal of Tuberculosis and Lung Disease, June 2018, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  7. Time to revise WHO-recommended definitions of MDR-TB treatment outcomes

    Article • The Lancet Respiratory Medicine, April 2018, Elsevier

    Dr Frank van Leth

  8. Treatment responses in multidrug-resistant tuberculosis in Germany

    Article • The International Journal of Tuberculosis and Lung Disease, April 2018, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  9. Relapse-free cure from multidrug-resistant tuberculosis in Germany

    Article • European Respiratory Journal, February 2018, European Respiratory Society (ERS)

    Dr Frank van Leth

  10. Reply: Benefit of the Shorter Multidrug-Resistant Tuberculosis Treatment Regimen in California and Modified Eligibility Criteria

    Article • American Review of Respiratory Disease, December 2017, American Thoracic Society

    Dr Frank van Leth, Professor JEROME ROBERT, Dr Valeriu Crudu

  11. Tuberculosis Treatment Outcomes in Europe: Based on Treatment Completion, Not Cure

    Article • American Review of Respiratory Disease, November 2017, American Thoracic Society

    Dr Frank van Leth, Dr Valeriu Crudu

  12. Tuberculosis resistance-conferring mutations with fitness cost among HIV-positive individuals in Uganda

    Article • The International Journal of Tuberculosis and Lung Disease, May 2017, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth, Willy SSENGOOBA

  13. A rapid method to assess the prevalence of antimicrobial resistance

    Article • Future Microbiology, April 2017, Future Medicine

    Dr Frank van Leth

  14. Antimicrobial resistance in uropathogens and appropriateness of empirical treatment: a population-based surveillance study in Indonesia

    Article • Journal of Antimicrobial Chemotherapy, January 2017, Oxford University Press (OUP)

    Dr Frank van Leth, R. Lia Kusumawati

  15. More on Treatment Outcomes in Multidrug-Resistant Tuberculosis

    Article • New England Journal of Medicine, December 2016, New England Journal of Medicine (NEJM/MMS)

    Dr Frank van Leth

  16. Prevention of Early Mortality by Presumptive Tuberculosis Therapy Study: An Open Label, Randomized Controlled Trial

    Article • American Journal of Tropical Medicine and Hygiene, December 2016, American Society of Tropical Medicine and Hygiene

    Dr Frank van Leth, Prof Robert Colebunders

  17. Effect of secondary preventive therapy on recurrence of tuberculosis in HIV-infected individuals: a systematic review

    Article • Infectious Diseases, December 2016, Taylor & Francis

    Dr Frank van Leth

  18. Limited Benefit of the New Shorter Multidrug-Resistant Tuberculosis Regimen in Europe

    Article • American Review of Respiratory Disease, October 2016, American Thoracic Society

    Dr Frank van Leth, Professor JEROME ROBERT, Dr Valeriu Crudu

  19. Population impact of factors associated with prevalent pulmonary tuberculosis in Tanzania

    Article • The International Journal of Tuberculosis and Lung Disease, October 2016, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  20. Urgent need to rethink treatment outcome definitions in tuberculosis

    Article • New England Journal of Medicine, September 2016, New England Journal of Medicine (NEJM/MMS)

    Dr Frank van Leth, Dr Valeriu Crudu

  21. Intention of physicians to implement guidelines for screening and treatment of latent tuberculosis infection in HIV-infected patients in The Netherlands: a mixed-method design

    Article • BMC Public Health, September 2016, Springer Science + Business Media

    Dr Frank van Leth

  22. Prevalence of pulmonary tuberculosis in adult population of Tanzania: a national survey, 2012

    Article • The International Journal of Tuberculosis and Lung Disease, August 2016, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  23. Viral Load and Risk of Tuberculosis in HIV Infection

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, February 2016, Wolters Kluwer Health

    Dr Frank van Leth, Dirk Wagner

  24. TB-HIV co-infection in the Netherlands: estimating prevalence and under-reporting in national registration databases using a capture–recapture analysis

    Article • Journal of Epidemiology & Community Health, December 2015, BMJ

    Dr Frank van Leth

  25. Beyond multidrug-resistant tuberculosis in Europe: a TBNET study

    Article • The International Journal of Tuberculosis and Lung Disease, December 2015, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth, Dr Valeriu Crudu

  26. Numbers needed to treat to prevent tuberculosis: TABLE 1

    Article • European Respiratory Journal, November 2015, European Respiratory Society (ERS)

    Professor Martina Sester, Dr Frank van Leth

  27. Health care-seeking behaviour among people with cough in Tanzania: findings from a tuberculosis prevalence survey

    Article • The International Journal of Tuberculosis and Lung Disease, June 2015, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  28. Latent tuberculosis infection as a target for tuberculosis control

    Article • Future Microbiology, June 2015, Future Medicine

    Dr Frank van Leth

  29. Factors associated with poor knowledge among adults on tuberculosis in Bangladesh: results from a nationwide survey

    Article • Journal of Health Population and Nutrition, May 2015, Springer Science + Business Media

    Dr Frank van Leth

  30. Multidrug-Resistant Tuberculosis in Europe, 2010–2011

    Article • Emerging Infectious Diseases, March 2015, Centers for Disease Control and Prevention (CDC)

    Dr Valeriu Crudu, Dr Valeriu Crudu, Dr Simon Tiberi, Dr Emanuele Pontali, Dr Frank van Leth

  31. Implementation of tuberculosis infection prevention and control in Mozambican health care facilities

    Article • The International Journal of Tuberculosis and Lung Disease, January 2015, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  32. Healthcare Workers' Challenges in the Implementation of Tuberculosis Infection Prevention and Control Measures in Mozambique

    Article • PLoS ONE, December 2014, PLOS

    Dr Frank van Leth

  33. Risk Assessment of Tuberculosis in Immunocompromised Patients. A TBNET Study

    Article • American Review of Respiratory Disease, November 2014, American Thoracic Society

    Dr Frank van Leth, Dirk Wagner

  34. Availability, price and affordability of anti-tuberculosis drugs in Europe: a TBNET survey

    Article • European Respiratory Journal, November 2014, European Respiratory Society (ERS)

    Dr Frank van Leth

  35. Validation of indirect tuberculosis treatment adherence measures in a resource-constrained setting

    Article • The International Journal of Tuberculosis and Lung Disease, July 2014, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  36. Antimicrobial drug resistance among clinically relevant bacterial isolates in sub-Saharan Africa: a systematic review

    Article • Journal of Antimicrobial Chemotherapy, May 2014, Oxford University Press (OUP)

    Dr Frank van Leth

  37. Care seeking in tuberculosis: results from a countrywide cluster randomised survey in Bangladesh

    Article • BMJ Open, May 2014, BMJ

    Dr Frank van Leth

  38. Embracing the challenges of HIV-TB co-infection in children [Editorial]

    Article • The International Journal of Tuberculosis and Lung Disease, April 2014, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  39. Management of patients with multidrug-resistant/extensively drug-resistant tuberculosis in Europe: a TBNET consensus statement

    Article • European Respiratory Journal, March 2014, European Respiratory Society (ERS)

    Dr Valeriu Crudu, Dr Valeriu Crudu, Dr Frank van Leth, Dr Enrico Tortoli, Dirk Wagner

  40. Antiretroviral therapy and tuberculosis: does the regimen matter?

    Article • Expert Review of Anti-infective Therapy, January 2014, Taylor & Francis

    Dr Frank van Leth

  41. Polio and the risk for the European Union

    Article • The Lancet, January 2014, Elsevier

    Dr Frank van Leth

  42. Design of pragmatic trials of tuberculosis interventions

    Article • The Lancet, January 2014, Elsevier

    Dr Frank van Leth

  43. Epidemiology of Tuberculosis in an Urban Slum of Dhaka City, Bangladesh

    Article • PLoS ONE, October 2013, PLOS

    Dr Frank van Leth

  44. TB diagnostic process management of patients in a referral hospital in Mozambique in comparison with the 2007 WHO recommendations for the diagnosis of smear-negative pulmonary TB and extrapulmonary TB

    Article • International Health, October 2013, Oxford University Press (OUP)

    Dr Frank van Leth

  45. Tuberculin survey in Bangladesh, 2007–2009: prevalence of tuberculous infection and implications for TB control

    Article • The International Journal of Tuberculosis and Lung Disease, October 2013, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  46. Epidemiological Surveys Embedded in Technical Assistance to Tuberculosis Control Programmes

    Article • The Open Infectious Diseases Journal, April 2013, Bentham Science Publishers

    Dr Frank van Leth

  47. Editorial - Technical Assistance to Tuberculosis Control Programmes as a Platform for Infectious Disease Research

    Article • The Open Infectious Diseases Journal, April 2013, Bentham Science Publishers

    Dr Frank van Leth

  48. Predictive Value of the Tuberculin Skin Test among Newly Arriving Immigrants

    Article • PLoS ONE, March 2013, PLOS

    Dr Frank van Leth

  49. Health workers’ performance in the implementation of Patient Centred Tuberculosis Treatment (PCT) strategy under programmatic conditions in Tanzania: a cross sectional study

    Article • BMC Health Services Research, March 2013, Springer Science + Business Media

    Dr Frank van Leth

  50. Benchmarking to Assess Potential Under-Diagnosis of Smear-Negative and Extrapulmonary Tuberculosis. A Case Study from Mozambique

    Article • The Open Infectious Diseases Journal, February 2013, Bentham Science Publishers

    Dr Frank van Leth

  51. Are routine tuberculosis programme data suitable to report on antiretroviral therapy use of HIV-infected tuberculosis patients?

    Article • BMC Research Notes, January 2013, Springer Science + Business Media

    Dr Frank van Leth

  52. Comparison of direct versus concentrated smear microscopy in detection of pulmonary tuberculosis

    Article • BMC Research Notes, January 2013, Springer Science + Business Media

    Dr Frank van Leth

  53. Risk of tuberculosis after antiretroviral treatment initiation: a comparison between efavirenz and nevirapine using inverse probability weighting

    Article • Antiviral Therapy, January 2013, International Medical Press

    Dr Frank van Leth

  54. Adherence to Tuberculosis Therapy among Patients Receiving Home-Based Directly Observed Treatment: Evidence from the United Republic of Tanzania

    Article • PLoS ONE, December 2012, PLOS

    Dr Frank van Leth

  55. Adherence by Dutch Public Health Nurses to the National Guidelines for Tuberculosis Contact Investigation

    Article • PLoS ONE, November 2012, PLOS

    Dr Frank van Leth

  56. Unrecognised tuberculosis at antiretroviral therapy initiation is associated with lower CD4+ T cell recovery

    Article • Tropical Medicine & International Health, November 2012, Wiley

    Dr Frank van Leth

  57. Socio Economic Position in TB Prevalence and Access to Services: Results from a Population Prevalence Survey and a Facility-Based Survey in Bangladesh

    Article • PLoS ONE, September 2012, PLOS

    Dr Frank van Leth

  58. Implementation and effect of intensified case finding on diagnosis of tuberculosis in a large urban HIV clinic in Uganda: a retrospective cohort study.

    Article • BMC Public Health, August 2012, Springer Science + Business Media

    Dr Frank van Leth

  59. The effect of tuberculosis and antiretroviral treatment on CD4+ cell count response in HIV-positive tuberculosis patients in Mozambique

    Article • BMC Public Health, August 2012, Springer Science + Business Media

    Dr Frank van Leth

  60. Comment on: Predictors of immune recovery and the association with late mortality while on antiretroviral treatment in Cambodia

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, May 2012, Oxford University Press (OUP)

    Dr Frank van Leth

  61. Role of the QuantiFERON®-TB Gold In-Tube assay in screening new immigrants for tuberculosis infection

    Article • European Respiratory Journal, April 2012, European Respiratory Society (ERS)

    Dr Frank van Leth

  62. Multidrug Resistance Among New Tuberculosis Cases

    Article • Epidemiology, March 2012, Wolters Kluwer Health

    Dr Frank van Leth

  63. Comparison of Macroscopic and Microscopic Assessment of Specimens Collected for the Diagnosis of Tuberculosis

    Article • The Open Infectious Diseases Journal, February 2012, Bentham Science Publishers

    Dr Frank van Leth

  64. Earlier initiation of antiretroviral therapy, increased tuberculosis case finding and reduced mortality in a setting of improved HIV care: a retrospective cohort study

    Article • HIV Medicine, February 2012, Wiley

    Dr Frank van Leth

  65. Contact tracing in low-incidence tuberculosis settings

    Article • The International Journal of Tuberculosis and Lung Disease, December 2011, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  66. Coverage and yield of tuberculosis contact investigations in the Netherlands

    Article • The International Journal of Tuberculosis and Lung Disease, December 2011, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  67. Incidence and Predictors of Mortality and the Effect of Tuberculosis Immune Reconstitution Inflammatory Syndrome in a Cohort of TB/HIV Patients Commencing Antiretroviral Therapy

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, September 2011, Wolters Kluwer Health

    Dr Frank van Leth, Prof Robert Colebunders

  68. Prevalence of smear-positive tuberculosis in persons aged ⩾15 years in Bangladesh: results from a national survey, 2007–2009

    Article • Epidemiology and Infection, August 2011, Cambridge University Press

    Dr Frank van Leth

  69. Highlights of a Symposium, Malaria: Where are we Today, Where are we Going?

    Article • The Open Infectious Diseases Journal, July 2011, Bentham Science Publishers

    Dr Frank van Leth

  70. Evaluation of the Genotype® MTBDRplus assay as a tool for drug resistance surveys

    Article • The International Journal of Tuberculosis and Lung Disease, July 2011, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  71. Health-seeking norms for tuberculosis symptoms in southern Angola: implications for behaviour change communications

    Article • The International Journal of Tuberculosis and Lung Disease, July 2011, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  72. Measuring socio-economic data in tuberculosis prevalence surveys

    Article • The International Journal of Tuberculosis and Lung Disease, June 2011, International Union Against Tuberculosis and Lung Disease

    Dr Frank van Leth

  73. Missed opportunities in tuberculosis control in The Netherlands due to prioritization of contact investigations

    Article • European Journal of Public Health, March 2011, Oxford University Press (OUP)

    Dr Frank van Leth

  74. Patient-centred tuberculosis treatment delivery under programmatic conditions in Tanzania: a cohort study

    Article • BMC Medicine, December 2009, Springer Science + Business Media

    Dr Frank van Leth

  75. Malnutrition: More that the eye can see

    Article • East African Medical Journal, October 2009, African Journals Online (AJOL)

    Dr Frank van Leth

  76. Projection of the number of patients with tuberculosis in the Netherlands in 2030

    Article • European Journal of Public Health, April 2009, Oxford University Press (OUP)

    Dr Frank van Leth

  77. Implementation of a national anti-tuberculosis drug resistance survey in Tanzania

    Article • BMC Public Health, December 2008, Springer Science + Business Media

    Dr Frank van Leth

  78. Risk Factors for Smear Negative And Culture Positive Results Among Pulmonary Tuberculosis Patients in Mwanza, Tanzania

    Article • The Open Tropical Medicine Journal, October 2008, Bentham Science Publishers

    Dr Frank van Leth

  79. Determination of Clinically Relevant Cutoffs for HIV-1 Phenotypic Resistance Estimates Through a Combined Analysis of Clinical Trial and Cohort Data

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, May 2008, Wolters Kluwer Health

    Dr Frank van Leth

  80. Measuring tuberculosis burden, trends, and the impact of control programmes

    Article • The Lancet Infectious Diseases, April 2008, Elsevier

    Dr Frank van Leth

  81. Prevalence of tuberculous infection and incidence of tuberculosis; a re-assessment of the Styblo rule

    Article • Bulletin of the World Health Organization, January 2008, WHO Press

    Dr Frank van Leth

  82. Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance: Response

    Article • BMC Medical Research Methodology, March 2007, Springer Science + Business Media

    Dr Frank van Leth

  83. Epstein‐Barr Virus Infects B and Non‐B Lymphocytes in HIV‐1–Infected Children and Adolescents

    Article • The Journal of Infectious Diseases, November 2006, Oxford University Press (OUP)

    Dr Frank van Leth

  84. Plasma lipid concentrations after 1.5 years of exposure to nevirapine or efavirenz together with stavudine and lamivudine

    Article • HIV Medicine, September 2006, Wiley

    Dr Frank van Leth

  85. Pharmacokinetic Parameters of Nevirapine and Efavirenz in Relation to Antiretroviral Efficacy

    Article • AIDS Research and Human Retroviruses, March 2006, Mary Ann Liebert Inc

    Dr Frank van Leth

  86. Long-term Experience With Combination Antiretroviral Therapy That Contains Nelfinavir for up to 7 Years in a Pediatric Cohort

    Article • PEDIATRICS, March 2006, American Academy of Pediatrics (AAP)

    Dr Frank van Leth

  87. Pharmacokinetics of Nevirapine: Once-Daily Versus Twice-Daily Dosing in the 2NN Study

    Article • HIV Clinical Trials, October 2005, Taylor & Francis

    Dr Frank van Leth

  88. Protease inhibitors and non-nucleoside reverse transcriptase inhibitors have a comparable effect on the CD4 cell change after switching to tenofovir-based regimens

    Article • AIDS, October 2005, Wolters Kluwer Health

    Dr Frank van Leth

  89. Cytomegalovirus rather than HIV triggers the outgrowth of effector CD8+CD45RA+CD27− T cells in HIV-1-infected children

    Article • AIDS, July 2005, Wolters Kluwer Health

    Dr Frank van Leth

  90. Nevirapine and Efavirenz Elicit Different Changes in Lipid Profiles in Antiretroviral- Therapy-Naive Patients Infected with HIV-1

    Article • PLoS Medicine, October 2004, PLOS

    Dr Frank van Leth

  91. Highly active antiretroviral therapy with or without mycophenolate mofetil in treatment-naive HIV-1 patients

    Article • AIDS, September 2004, Wolters Kluwer Health

    Dr Frank van Leth

  92. Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study

    Article • The Lancet, April 2004, Elsevier

    Dr Frank van Leth

  93. Lipid Profiles in HIV‐Infected Patients Receiving Combination Antiretroviral Therapy: Are Different Antiretroviral Drugs Associated with Different Lipid Profiles?

    Article • The Journal of Infectious Diseases, March 2004, Oxford University Press (OUP)

    Dr Frank van Leth

  94. Differential CD4 T-cell response in HIV-1-infected patients using protease inhibitor-based or nevirapine-based highly active antiretroviral therapy

    Article • HIV Medicine, March 2004, Wiley

    Dr Frank van Leth

  95. Disseminating Health Care Innovation

    Article • JAMA, September 2003, American Medical Association (AMA)

    Dr Frank van Leth

  96. A randomized trial to study first-line combination therapy with or without a protease inhibitor in HIV-1-infected patients

    Article • AIDS, May 2003, Wolters Kluwer Health

    Dr Frank van Leth

  97. Identifying malnourished children may not be easy

    Article • BMJ, April 2003, BMJ

    Dr Frank van Leth

  98. Highly Active Antiretroviral Therapy-Induced Lipodystrophy Has Minor Effects on Human Immunodeficiency Virus-Induced Changes in Lipolysis, but Normalizes Resting Energy Expenditure

    Article • The Journal of Clinical Endocrinology & Metabolism, November 2002, Endocrine Society

    Dr Frank van Leth

  99. Nevirapine-containing antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile

    Article • AIDS, December 2001, Wolters Kluwer Health

    Dr Frank van Leth