All Stories

  1. Reporting patterns of adverse drug withdrawal events using individual case safety reports in United States and European databases
  2. Prescription intervals of medications for chronic use: a cohort study
  3. Strengthening Pharmacovigilance Reporting for Withdrawal Reactions to Support Deprescribing
  4. Avoiding being the “busy fool”: How general practitioners perceive and engage with a prescribing safety and quality dashboard
  5. An ageing biomarker signature predicts chronic disease cluster trajectories, physical function and mortality: validation in the TILDA and HRS cohorts
  6. Trends in the Chronic Use and Discontinuation of Potentially Inappropriate Medications in Older Adults
  7. Characterising prescribing cascades in older community-dwelling adults attending general practice in The Netherlands: a retrospective cohort study
  8. An essential medicines list in Ireland: A qualitative interview study of interest-holders
  9. Adverse Drug Reaction-Related Hospital Admissions and Adverse Drug Events and Their Association with Short- and Long-Term Health Outcomes in Older Adults
  10. A Methodological Review of Simulation Studies Published in Pharmacoepidemiology and Drug Safety
  11. Identifying core teamwork competencies for community-based health and social care professionals: an e-Delphi study
  12. Analysing the impact of complex multimorbidity on health-related quality of life
  13. Prevalence and impact of prescribing cascades in community‐dwelling adults: Longitudinal analysis of the Irish longitudinal study on ageing (TILDA)
  14. The association between STOPPFall medication use and orthostatic hypotension in community-dwelling older people
  15. Identifying outcomes for evaluating the impact of pharmacist prescribing: A rapid overview of reviews.
  16. Changes in benzodiazepine, z-drug, and other sedative prescribing in primary care in Ireland between 2014 and 2022
  17. Potentially inappropriate prescribing and falls-risk increasing drugs in people who have experienced a fall: a systematic review and meta-analysis
  18. An essential medicines list in Ireland: A qualitative interview study of interest-holders
  19. Pharmaceutical company promotional payments to English general practices: longitudinal study
  20. Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study
  21. Identifying predictors of medication-related harm in older populations: a latent class analysis approach
  22. Medicines support and socIal prescribing to aDdress pAtient prioritieS in multimorbidity (MIDAS): A process evaluation protocol
  23. The healthcare costs of poor air quality in Ireland: A review of potential data sources and methods
  24. Developing and assessing the usability of a prescribing quality and safety dashboard in Irish general practice: protocol for a qualitative study
  25. Effectiveness of interactive dashboards to optimize prescribing in general practice: a systematic review
  26. Impact of eliciting treatment priorities on analgesic prescribing in older patients with high levels of polypharmacy
  27. Medicines support and social prescribing to address patient priorities in multimorbidity (MIDAS): protocol for a definitive, multi-arm, cluster randomised, controlled trial in Irish general practice
  28. RxTrends: An R-based Shiny Application for Visualising Open Data on Prescribed Medications in Ireland
  29. Added Therapeutic Benefits of Top‐Selling Drugs in Japan: A Cross‐Sectional Study Using Health Technology Assessment
  30. Pharmacoepidemiology simulation study practices: A methodological review
  31. The association between STOPPFall medication use and falls and fractures in community-dwelling older people
  32. Shortcomings in reporting country-level participation in multicenter randomized controlled trials involving Ireland as a collaborating partner: a metaresearch study
  33. Prevalence of potentially inappropriate prescribing in community-dwelling older adults: an application of STOPP/START version 3 to The Irish Longitudinal Study on Ageing (TILDA)
  34. Potentially inappropriate prescribing and falls-risk increasing drugs in people who have experienced a fall; a systematic review and meta-analysis
  35. Out-of-pocket prescription medicine expenditure amongst community-dwelling adults: Findings from the Irish longitudinal study on ageing (TILDA) in 2016
  36. RxTrends: An R-based Shiny Application for Visualising Open Data on Prescribed Medications in Ireland
  37. Use of complementary and alternative medicine (CAM) among people living with Sjögren’s: a cross-sectional survey using a modified international CAM questionnaire (I-CAM-Q)
  38. Effectiveness of interactive dashboards to optimise prescribing in primary care: a protocol for a systematic review
  39. Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures
  40. Associations between pharmaceutical industry interactions and prescribing practices in chronic non-malignant pain management: A protocol for a systematic review
  41. Modelling the impact of changes to prescription medicine cost-sharing schemes among middle aged and older adults
  42. Adverse drug reactions and events in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development and validation of a model for predicting adverse drug reactions and events in older patients
  43. Prevalence and predictors of sub-optimal laboratory monitoring of selected higher risk medicines in Irish general practice: a 5-year retrospective cohort study of community-dwelling older adults
  44. Development and Implementation of Deprescribing Guidelines
  45. Optimising Medication Therapy in Older People
  46. Core medication use in general practice prescriptions: A pilot study evaluating the Drug Utilization 90% Index in Irish general practice
  47. Trends and patterns of sedative prescribing in primary care in Ireland between 2014 and 2022 - a repeated cross-sectional study
  48. Potentially inappropriate prescribing in middle-aged adults: a significant problem with a lack of action and evidence to address it
  49. The Association Between Psychotropic Medication Use and Gait and Mobility Impairment in Community-Dwelling Older People: Data From The Irish Longitudinal Study on Ageing (TILDA)
  50. Evaluation of real-world evidence to assess health outcomes related to deprescribing medications in older adults: an International Society for Pharmacoepidemiology–endorsed systematic review of methodology
  51. Drug company methodologies used for reporting in the UK pharmaceutical industry payment transparency database between 2015 and 2019: A content analysis
  52. Patterns of pain medication usage and self-reported pain in older Irish adults with osteoarthritis: A latent class analysis of data from the Irish Longitudinal Study on Ageing
  53. Time Trends, Regional Variation and Associations of Low‐Allergy Formula Prescribing in England
  54. Medication adherence for people with acquired communication disorders: A systematic review
  55. Top 10 Signs and Symptoms of Psychotropic Adverse Drug Events to Monitor in Residents of Long-Term Care Facilities
  56. Cost effectiveness of a GP delivered medication review to reduce polypharmacy and potentially inappropriate prescribing in older patients with multimorbidity in Irish primary care: the SPPiRE cluster randomised controlled trial
  57. Effectiveness of interactive dashboards to optimise prescribing in general practice: A systematic review
  58. Out-of-pocket prescription medicine expenditure amongst community-dwelling adults: findings from The Irish Longitudinal Study on Ageing (TILDA) in 2016
  59. The Development of Principles for Patient and Public Involvement (PPI) in Preclinical Spinal Cord Research: A Modified Delphi Study
  60. Effectiveness of interactive dashboards to optimise prescribing in primary care: a protocol for a systematic review
  61. Continued cancer drug approvals in Japan and Europe after market withdrawal in the United States: A comparative study of accelerated approvals
  62. Prevalence and risk factors for milk allergy overdiagnosis in the BEEP trial cohort
  63. Evaluating time to withdrawal of anti-cancer drug indications that received FDA’s accelerated approval
  64. Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022 - a repeated cross-sectional study
  65. Stakeholder perceptions of and attitudes towards problematic polypharmacy and prescribing cascades: a qualitative study
  66. Payments to healthcare organisations reported by the medical device industry in Europe from 2017 to 2019: An observational study
  67. Adverse Drug reactions in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development of a model for predicting adverse drug reaction-related hospital admissions in older patients
  68. What do clinical practice guidelines say about deprescribing? A scoping review
  69. Reducing potentially inappropriate polypharmacy at a national and international level: the impact of deprescribing networks
  70. Measuring Quality of Life in Deprescribing Trials: A Scoping Review
  71. Epidemiology and management of oral cavity squamous cell carcinoma in Ireland
  72. The role of Patient and public involvement (PPI) in pre-clinical spinal cord research: An interview study
  73. Primary care prescribing prior to lung cancer diagnosis (PPP-Lung): protocol for a systematic review
  74. Pediatric blood cultures—turning up the volume: a before and after intervention study
  75. Drug company methodologies used for reporting in the UK pharmaceutical industry payment transparency database between 2015-2019: A content analysis
  76. Paediatric Escherichia coli urinary tract infection: susceptibility trends and clinical management—a retrospective analysis of a 10-year period
  77. Challenges in identifying and quantifying country-level participation in multi-country randomised controlled trials involving Ireland as a collaborating partner
  78. Perspectives of researchers and clinicians on patient and public involvement (PPI) in preclinical spinal cord research: An interview study
  79. Potentially Inappropriate Prescribing and Potential Prescribing Omissions and Their Association with Adverse Drug Reaction-Related Hospital Admissions
  80. Drug–drug interactions and the risk of adverse drug reaction‐related hospital admissions in the older population
  81. Trends in medication use at the onset of and during the COVID‐19 pandemic in the Republic of Ireland: An interrupted time series study
  82. Prescribing differences among older adults with differing health cover and socioeconomic status: a cohort study
  83. Medication Adherence for People with Acquired Communication Disorders: A Systematic Review
  84. Eligibility rates and representativeness of the General Medical Services scheme population in Ireland 2016-2021: A methodological report
  85. Effect of COVID-19 vaccines for the treatment of people with post-COVID-19 condition: a rapid review
  86. Perspectives of Researchers and Clinicians on Patient and Public Involvement (PPI) in Preclinical Spinal Cord Research: An Interview Study
  87. The role of Patient and Public Involvement (PPI) in pre-clinical spinal cord research: an interview study
  88. Potentially inappropriate prescribing in middle-aged adults: A significant problem with a lack of action and evidence to address it.
  89. Survival in an era of organ preservation: an update on laryngeal cancer in Ireland
  90. Trends in medication use after the onset of the COVID-19 pandemic in the Republic of Ireland: an interrupted time series study
  91. Use of pharmacy services in community-dwelling middle-aged and older adults; findings from The Irish Longitudinal Study on Ageing (TILDA)
  92. The impact of lidocaine plaster prescribing reduction strategies: A comparison of two national health services in Europe
  93. Deprescribing and medicines optimisation, two sides of the same coin? Considerations for design of interventional studies
  94. Clinical study reports published by the European Medicines Agency 2016–2018: a cross-sectional analysis
  95. A blended model to support brief interventions in primary care: A qualitative study of usability and acceptability of HealthEir in community pharmacy
  96. Payments to healthcare organisations reported by the medical device industry in Europe from 2017 to 2019: an observational study
  97. The association between weather warnings and hip fractures in the Republic of Ireland
  98. Recruiting general practitioners and older patients with multimorbidity to randomized trials
  99. Prescribing differences among older adults with differing health cover and socioeconomic status: a cohort study
  100. Association between patient attitudes towards deprescribing and subsequent prescription changes
  101. Use of pharmacy services in community-dwelling middle-aged and older adults; findings from The Irish Longitudinal Study on Ageing (TILDA)
  102. Formal health care costs among older people in Ireland: methods and estimates using The Irish Longitudinal Study on Ageing (TILDA)
  103. The impact of lidocaine plaster prescribing reduction strategies: a comparison of two national health services in Europe
  104. Value assessment of deprescribing interventions: Suggestions for improvement
  105. Deprescribing and medicines optimisation, two sides of the same coin? Considerations for design of interventional studies
  106. The effectiveness and cost of integrating pharmacists within general practice to optimize prescribing and health outcomes in primary care patients with polypharmacy: a systematic review
  107. Association between patient attitudes towards deprescribing and subsequent prescription changes
  108. The effectiveness and cost of integrating pharmacists within general practice to optimize prescribing and health outcomes in primary care patients with polypharmacy: A systematic review
  109. Is There Evidence of an Association Between Acute Health Care Utilization and Function in Older Adults Over Time? A Population-Based Cohort Study
  110. Key items for reports of primary care research: an international Delphi study
  111. Medication safety incidents associated with the remote delivery of primary care: a rapid review
  112. Overprescribing among older people near end of life in Ireland: Evidence of prevalence and determinants from The Irish Longitudinal Study on Ageing (TILDA)
  113. Medication changes and potentially inappropriate prescribing in older patients with significant polypharmacy
  114. Adverse drug reactions and associated patient characteristics in older community-dwelling adults: a 6-year prospective cohort study
  115. Effect of COVID-19 vaccines for the treatment of people with post-COVID-19 condition: a rapid review
  116. Eligibility rates and representativeness of the General Medical Services scheme population in Ireland 2017-2021: A methodological report
  117. Patient and general practitioner experiences of implementing a medication review intervention in older people with multimorbidity: Process evaluation of the SPPiRE trial
  118. Direct-to-consumer genetic testing: an updated systematic review of healthcare professionals’ knowledge and views, and ethical and legal concerns
  119. Prescribing cascades in community‐dwelling adults: A systematic review
  120. Evaluation of policies and practices to support safe and appropriate analgesic and sedative prescribing: The CDRx (controlled drug prescribing) protocol
  121. What is the impact of multimorbidity on out-of-pocket healthcare expenditure among community-dwelling older adults in Ireland? A cross-sectional study
  122. Medication changes  and potentially inappropriate prescribing in older patients with significant  polypharmacy: a secondary analysis of the SPPiRE trial            
  123. Prescribing cascades in community-dwelling adults: a systematic review
  124. Prescribing trends in older patients with multimorbidity and significant polypharmacy recruited to the SPPiRE trial
  125. Development of the ADFICE_IT Models for Predicting Falls and Recurrent Falls in Community-Dwelling Older Adults: Pooled Analyses of European Cohorts With Special Attention to Medication
  126. Hospital initiation of benzodiazepines and Z-drugs in older adults and discontinuation in primary care
  127. Cost outcomes of potentially inappropriate prescribing in middle‐aged adults: A Delphi consensus and cross‐sectional study
  128. Methods for evaluating the benefit and harms of deprescribing in observational research using routinely collected data
  129. GP-delivered medication review of polypharmacy, deprescribing, and patient priorities in older people with multimorbidity in Irish primary care (SPPiRE Study): A cluster randomised controlled trial
  130. A systematic review of the prevalence, determinants, and impact of potentially inappropriate prescribing in middle-aged adults
  131. ‘More of an art than a science’? The development, design and mechanics of the Delphi Technique
  132. Opioid and analgesic utilization in Ireland in 2000 and 2015: A repeated cross‐sectional study
  133. Prescribing cascades in community-dwelling adults: protocol for a systematic review
  134. Blood-Brain Barrier Crossing Renin-Angiotensin Drugs and Cognition in the Elderly: A Meta-Analysis
  135. GPs’ perceptions of their relationship with the pharmaceutical industry: a qualitative study
  136. Prescribing cascades in community-dwelling adults: protocol for a systematic review
  137. Age alone is not a barrier to concurrent chemoradiotherapy for advanced head and neck cancer
  138. Persistence with oral bisphosphonates and denosumab among older adults in primary care in Ireland
  139. Efficacy and safety of sacubitril/valsartan in the treatment of heart failure: protocol for a systematic review incorporating unpublished clinical study reports
  140. Prognostic Significance of Glucocorticoid Receptor Expression in Cancer: A Systematic Review and Meta-Analysis
  141. How many medications do doctors in primary care use? An observational study of the DU90% indicator in primary care in England
  142. Prevalence and predictors of potentially inappropriate prescribing in middle-aged adults: a repeated cross-sectional study
  143. Cognitive decline associated with anticholinergics, benzodiazepines and Z‐drugs: Findings from The Irish Longitudinal Study on Ageing (TILDA)
  144. Factors associated with initiation of bone-health medication among older adults in primary care in Ireland
  145. Persistence with oral bisphosphonates and denosumab among older adults in primary care in Ireland
  146. Aspirin prescribing in cardiovascular disease in middle-aged and older adults in Ireland: findings from The Irish Longitudinal Study on Ageing
  147. Hospital initiation of benzodiazepines and Z-drugs in older adults and discontinuation in primary care
  148. How many medications do doctors in primary care use? An observational study of the DU90% indicator in primary care in England.
  149. Evaluation of the General Practice Pharmacist (GPP) intervention to optimise prescribing in Irish primary care: a non-randomised pilot study
  150. Cognitive decline associated with anticholinergics, benzodiazepines, and Z-drugs: findings from The Irish Longitudinal Study on Ageing (TILDA)
  151. Pharmacists in general practice: a qualitative process evaluation of the General Practice Pharmacist (GPP) study
  152. The Development of an Accreditation Framework for Continuing Education Activities for Pharmacists
  153. High-risk categories for COVID-19 and their distribution by county in Republic of Ireland-evidence from the TILDA study
  154. TILDA report to inform demographics for over 50s in Ireland for COVID-19 crisis
  155. Efficacy and safety of sacubitril/valsartan in the treatment of heart failure: protocol for a systematic review incorporating unpublished clinical study reports
  156. A comparison of contemporary versus older studies of aspirin for primary prevention
  157. Comparing Potentially Inappropriate Prescribing Tools and Their Association With Patient Outcomes
  158. Evaluation of the General Practice Pharmacist (GPP) intervention to optimise prescribing in Irish primary care: a non‐randomised pilot study
  159. Potentially serious alcohol–medication interactions and falls in community-dwelling older adults: a prospective cohort study
  160. Association of Antidepressants With Recurrent, Injurious and Unexplained Falls is Not Explained by Reduced Gait Speed
  161. A comparison of contemporary versus older studies of aspirin for primary prevention
  162. Modification of Potentially Inappropriate Prescribing Following Fall-Related Hospitalizations in Older Adults
  163. Prescriber Variation in Relation to Prescribing Trends within the Preferred Drugs Initiative in Ireland (2012–2015): An Interrupted Time-Series Study Using Latent Curve Models
  164. Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models
  165. Prevalence of potentially inappropriate prescribing in older people in primary care and its association with hospital admission: longitudinal study
  166. Self-report versus electronic medical record recorded healthcare utilisation in older community-dwelling adults: Comparison of two prospective cohort studies
  167. Prescribing Variation in General Practices in England Following a Direct Healthcare Professional Communication on Mirabegron
  168. The PIPc Study—application of indicators of potentially inappropriate prescribing in children (PIPc) to a national prescribing database in Ireland: a cross-sectional prevalence study
  169. Prescribing Variation in General Practices in England Following a Direct Healthcare Professional Communication on Mirabegron
  170. Deprescribing guidelines: An international symposium on development, implementation, research and health professional education
  171. Deprescribing recommendations: An essential consideration for clinical guideline developers
  172. Deprescribing: Future directions for research
  173. Fixed-dose combination antihypertensives and risk of medication errors
  174. Supporting prescribing in Irish primary care: protocol for a non-randomised pilot study of a general practice pharmacist (GPP) intervention to optimise prescribing in primary care
  175. An evaluation of prescribing trends and patterns of claims within the Preferred Drugs Initiative in Ireland (2011–2016): an interrupted time-series study
  176. A narrative review of the safety concerns of deprescribing in older adults and strategies to mitigate potential harms
  177. Potentially inappropriate prescribing and its association with health outcomes in middle-aged people: a prospective cohort study in Ireland
  178. Supporting prescribing in older people with multimorbidity and significant polypharmacy in primary care (SPPiRE): a cluster randomised controlled trial protocol and pilot
  179. Characterizing Potentially Inappropriate Prescribing of Proton Pump Inhibitors in Older People in Primary Care in Ireland from 1997 to 2012
  180. PIPc study: development of indicators of potentially inappropriate prescribing in children (PIPc) in primary care using a modified Delphi technique
  181. Potentially inappropriate prescribing according to STOPP and START and adverse outcomes in community-dwelling older people: a prospective cohort study
  182. Potentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria
  183. Trends and interaction of polypharmacy and potentially inappropriate prescribing in primary care over 15 years in Ireland: a repeated cross-sectional study
  184. Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people
  185. Potentially Inappropriate Medicines and Potential Prescribing Omissions in Older People and Their Association With Health Care Utilization: A Retrospective Cohort Study
  186. Potentially Inappropriate Prescribing and Vulnerability and Hospitalization in Older Community-Dwelling Patients
  187. Prevalence of potentially inappropriate prescribing and prescribing omissions in older Irish adults: findings from The Irish LongituDinal Study on Ageing study (TILDA)
  188. Potentially Inappropriate Prescribing (PIP) and Its Association with Instrumental Activities of Daily Living (IADL) Impairment in Older People