All Stories

  1. Identification of Potentially Inappropriate Medications for Adults Below 65 Years: Protocol for a Modified Delphi Study
  2. Reporting patterns of adverse drug withdrawal events using individual case safety reports in United States and European databases
  3. Prescription intervals of medications for chronic use: a cohort study
  4. Strengthening Pharmacovigilance Reporting for Withdrawal Reactions to Support Deprescribing
  5. Medical Device Industry Payments to Healthcare Professionals and Organizations in Japan: An Evaluation of Scale, Distribution, and Transparency Practices, 2019-2022
  6. Avoiding being the “busy fool”: How general practitioners perceive and engage with a prescribing safety and quality dashboard
  7. An ageing biomarker signature predicts chronic disease cluster trajectories, physical function and mortality: validation in the TILDA and HRS cohorts
  8. Trends in the Chronic Use and Discontinuation of Potentially Inappropriate Medications in Older Adults
  9. Characterising prescribing cascades in older community-dwelling adults attending general practice in The Netherlands: a retrospective cohort study
  10. An essential medicines list in Ireland: A qualitative interview study of interest-holders
  11. Adverse Drug Reaction-Related Hospital Admissions and Adverse Drug Events and Their Association with Short- and Long-Term Health Outcomes in Older Adults
  12. A Methodological Review of Simulation Studies Published in Pharmacoepidemiology and Drug Safety
  13. Identifying core teamwork competencies for community-based health and social care professionals: an e-Delphi study
  14. Analysing the impact of complex multimorbidity on health-related quality of life
  15. Prevalence and impact of prescribing cascades in community‐dwelling adults: Longitudinal analysis of the Irish longitudinal study on ageing (TILDA)
  16. The association between STOPPFall medication use and orthostatic hypotension in community-dwelling older people
  17. Identifying outcomes for evaluating the impact of pharmacist prescribing: A rapid overview of reviews.
  18. Changes in benzodiazepine, z-drug, and other sedative prescribing in primary care in Ireland between 2014 and 2022
  19. Potentially inappropriate prescribing and falls-risk increasing drugs in people who have experienced a fall: a systematic review and meta-analysis
  20. An essential medicines list in Ireland: A qualitative interview study of interest-holders
  21. Pharmaceutical company promotional payments to English general practices: longitudinal study
  22. Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study
  23. Identifying predictors of medication-related harm in older populations: a latent class analysis approach
  24. Medicines support and socIal prescribing to aDdress pAtient prioritieS in multimorbidity (MIDAS): A process evaluation protocol
  25. The healthcare costs of poor air quality in Ireland: A review of potential data sources and methods
  26. Developing and assessing the usability of a prescribing quality and safety dashboard in Irish general practice: protocol for a qualitative study
  27. Effectiveness of interactive dashboards to optimize prescribing in general practice: a systematic review
  28. Impact of eliciting treatment priorities on analgesic prescribing in older patients with high levels of polypharmacy
  29. Medicines support and social prescribing to address patient priorities in multimorbidity (MIDAS): protocol for a definitive, multi-arm, cluster randomised, controlled trial in Irish general practice
  30. RxTrends: An R-based Shiny Application for Visualising Open Data on Prescribed Medications in Ireland
  31. Added Therapeutic Benefits of Top‐Selling Drugs in Japan: A Cross‐Sectional Study Using Health Technology Assessment
  32. Pharmacoepidemiology simulation study practices: A methodological review
  33. The association between STOPPFall medication use and falls and fractures in community-dwelling older people
  34. Shortcomings in reporting country-level participation in multicenter randomized controlled trials involving Ireland as a collaborating partner: a metaresearch study
  35. Prevalence of potentially inappropriate prescribing in community-dwelling older adults: an application of STOPP/START version 3 to The Irish Longitudinal Study on Ageing (TILDA)
  36. Potentially inappropriate prescribing and falls-risk increasing drugs in people who have experienced a fall; a systematic review and meta-analysis
  37. Out-of-pocket prescription medicine expenditure amongst community-dwelling adults: Findings from the Irish longitudinal study on ageing (TILDA) in 2016
  38. RxTrends: An R-based Shiny Application for Visualising Open Data on Prescribed Medications in Ireland
  39. Use of complementary and alternative medicine (CAM) among people living with Sjögren’s: a cross-sectional survey using a modified international CAM questionnaire (I-CAM-Q)
  40. Effectiveness of interactive dashboards to optimise prescribing in primary care: a protocol for a systematic review
  41. Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures
  42. Associations between pharmaceutical industry interactions and prescribing practices in chronic non-malignant pain management: A protocol for a systematic review
  43. Modelling the impact of changes to prescription medicine cost-sharing schemes among middle aged and older adults
  44. Adverse drug reactions and events in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development and validation of a model for predicting adverse drug reactions and events in older patients
  45. Prevalence and predictors of sub-optimal laboratory monitoring of selected higher risk medicines in Irish general practice: a 5-year retrospective cohort study of community-dwelling older adults
  46. Development and Implementation of Deprescribing Guidelines
  47. Optimising Medication Therapy in Older People
  48. Core medication use in general practice prescriptions: A pilot study evaluating the Drug Utilization 90% Index in Irish general practice
  49. Trends and patterns of sedative prescribing in primary care in Ireland between 2014 and 2022 - a repeated cross-sectional study
  50. Potentially inappropriate prescribing in middle-aged adults: a significant problem with a lack of action and evidence to address it
  51. The Association Between Psychotropic Medication Use and Gait and Mobility Impairment in Community-Dwelling Older People: Data From The Irish Longitudinal Study on Ageing (TILDA)
  52. Evaluation of real-world evidence to assess health outcomes related to deprescribing medications in older adults: an International Society for Pharmacoepidemiology–endorsed systematic review of methodology
  53. Drug company methodologies used for reporting in the UK pharmaceutical industry payment transparency database between 2015 and 2019: A content analysis
  54. Patterns of pain medication usage and self-reported pain in older Irish adults with osteoarthritis: A latent class analysis of data from the Irish Longitudinal Study on Ageing
  55. Time Trends, Regional Variation and Associations of Low‐Allergy Formula Prescribing in England
  56. Medication adherence for people with acquired communication disorders: A systematic review
  57. Top 10 Signs and Symptoms of Psychotropic Adverse Drug Events to Monitor in Residents of Long-Term Care Facilities
  58. Cost effectiveness of a GP delivered medication review to reduce polypharmacy and potentially inappropriate prescribing in older patients with multimorbidity in Irish primary care: the SPPiRE cluster randomised controlled trial
  59. Effectiveness of interactive dashboards to optimise prescribing in general practice: A systematic review
  60. Out-of-pocket prescription medicine expenditure amongst community-dwelling adults: findings from The Irish Longitudinal Study on Ageing (TILDA) in 2016
  61. The Development of Principles for Patient and Public Involvement (PPI) in Preclinical Spinal Cord Research: A Modified Delphi Study
  62. Effectiveness of interactive dashboards to optimise prescribing in primary care: a protocol for a systematic review
  63. Continued cancer drug approvals in Japan and Europe after market withdrawal in the United States: A comparative study of accelerated approvals
  64. Prevalence and risk factors for milk allergy overdiagnosis in the BEEP trial cohort
  65. Evaluating time to withdrawal of anti-cancer drug indications that received FDA’s accelerated approval
  66. Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022 - a repeated cross-sectional study
  67. Stakeholder perceptions of and attitudes towards problematic polypharmacy and prescribing cascades: a qualitative study
  68. Payments to healthcare organisations reported by the medical device industry in Europe from 2017 to 2019: An observational study
  69. Adverse Drug reactions in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development of a model for predicting adverse drug reaction-related hospital admissions in older patients
  70. What do clinical practice guidelines say about deprescribing? A scoping review
  71. Reducing potentially inappropriate polypharmacy at a national and international level: the impact of deprescribing networks
  72. Measuring Quality of Life in Deprescribing Trials: A Scoping Review
  73. Epidemiology and management of oral cavity squamous cell carcinoma in Ireland
  74. The role of Patient and public involvement (PPI) in pre-clinical spinal cord research: An interview study
  75. Primary care prescribing prior to lung cancer diagnosis (PPP-Lung): protocol for a systematic review
  76. Pediatric blood cultures—turning up the volume: a before and after intervention study
  77. Drug company methodologies used for reporting in the UK pharmaceutical industry payment transparency database between 2015-2019: A content analysis
  78. Paediatric Escherichia coli urinary tract infection: susceptibility trends and clinical management—a retrospective analysis of a 10-year period
  79. Challenges in identifying and quantifying country-level participation in multi-country randomised controlled trials involving Ireland as a collaborating partner
  80. Perspectives of researchers and clinicians on patient and public involvement (PPI) in preclinical spinal cord research: An interview study
  81. Potentially Inappropriate Prescribing and Potential Prescribing Omissions and Their Association with Adverse Drug Reaction-Related Hospital Admissions
  82. Drug–drug interactions and the risk of adverse drug reaction‐related hospital admissions in the older population
  83. Trends in medication use at the onset of and during the COVID‐19 pandemic in the Republic of Ireland: An interrupted time series study
  84. Prescribing differences among older adults with differing health cover and socioeconomic status: a cohort study
  85. Medication Adherence for People with Acquired Communication Disorders: A Systematic Review
  86. Eligibility rates and representativeness of the General Medical Services scheme population in Ireland 2016-2021: A methodological report
  87. Effect of COVID-19 vaccines for the treatment of people with post-COVID-19 condition: a rapid review
  88. Perspectives of Researchers and Clinicians on Patient and Public Involvement (PPI) in Preclinical Spinal Cord Research: An Interview Study
  89. The role of Patient and Public Involvement (PPI) in pre-clinical spinal cord research: an interview study
  90. Potentially inappropriate prescribing in middle-aged adults: A significant problem with a lack of action and evidence to address it.
  91. Survival in an era of organ preservation: an update on laryngeal cancer in Ireland
  92. Trends in medication use after the onset of the COVID-19 pandemic in the Republic of Ireland: an interrupted time series study
  93. Use of pharmacy services in community-dwelling middle-aged and older adults; findings from The Irish Longitudinal Study on Ageing (TILDA)
  94. The impact of lidocaine plaster prescribing reduction strategies: A comparison of two national health services in Europe
  95. Deprescribing and medicines optimisation, two sides of the same coin? Considerations for design of interventional studies
  96. Clinical study reports published by the European Medicines Agency 2016–2018: a cross-sectional analysis
  97. A blended model to support brief interventions in primary care: A qualitative study of usability and acceptability of HealthEir in community pharmacy
  98. Payments to healthcare organisations reported by the medical device industry in Europe from 2017 to 2019: an observational study
  99. The association between weather warnings and hip fractures in the Republic of Ireland
  100. Recruiting general practitioners and older patients with multimorbidity to randomized trials
  101. Prescribing differences among older adults with differing health cover and socioeconomic status: a cohort study
  102. Association between patient attitudes towards deprescribing and subsequent prescription changes
  103. Use of pharmacy services in community-dwelling middle-aged and older adults; findings from The Irish Longitudinal Study on Ageing (TILDA)
  104. Formal health care costs among older people in Ireland: methods and estimates using The Irish Longitudinal Study on Ageing (TILDA)
  105. The impact of lidocaine plaster prescribing reduction strategies: a comparison of two national health services in Europe
  106. Value assessment of deprescribing interventions: Suggestions for improvement
  107. Deprescribing and medicines optimisation, two sides of the same coin? Considerations for design of interventional studies
  108. The effectiveness and cost of integrating pharmacists within general practice to optimize prescribing and health outcomes in primary care patients with polypharmacy: a systematic review
  109. Association between patient attitudes towards deprescribing and subsequent prescription changes
  110. The effectiveness and cost of integrating pharmacists within general practice to optimize prescribing and health outcomes in primary care patients with polypharmacy: A systematic review
  111. Is There Evidence of an Association Between Acute Health Care Utilization and Function in Older Adults Over Time? A Population-Based Cohort Study
  112. Key items for reports of primary care research: an international Delphi study
  113. Medication safety incidents associated with the remote delivery of primary care: a rapid review
  114. Overprescribing among older people near end of life in Ireland: Evidence of prevalence and determinants from The Irish Longitudinal Study on Ageing (TILDA)
  115. Medication changes and potentially inappropriate prescribing in older patients with significant polypharmacy
  116. Adverse drug reactions and associated patient characteristics in older community-dwelling adults: a 6-year prospective cohort study
  117. Effect of COVID-19 vaccines for the treatment of people with post-COVID-19 condition: a rapid review
  118. Eligibility rates and representativeness of the General Medical Services scheme population in Ireland 2017-2021: A methodological report
  119. Patient and general practitioner experiences of implementing a medication review intervention in older people with multimorbidity: Process evaluation of the SPPiRE trial
  120. Direct-to-consumer genetic testing: an updated systematic review of healthcare professionals’ knowledge and views, and ethical and legal concerns
  121. Prescribing cascades in community‐dwelling adults: A systematic review
  122. Evaluation of policies and practices to support safe and appropriate analgesic and sedative prescribing: The CDRx (controlled drug prescribing) protocol
  123. What is the impact of multimorbidity on out-of-pocket healthcare expenditure among community-dwelling older adults in Ireland? A cross-sectional study
  124. Medication changes  and potentially inappropriate prescribing in older patients with significant  polypharmacy: a secondary analysis of the SPPiRE trial            
  125. Prescribing cascades in community-dwelling adults: a systematic review
  126. Prescribing trends in older patients with multimorbidity and significant polypharmacy recruited to the SPPiRE trial
  127. Development of the ADFICE_IT Models for Predicting Falls and Recurrent Falls in Community-Dwelling Older Adults: Pooled Analyses of European Cohorts With Special Attention to Medication
  128. Hospital initiation of benzodiazepines and Z-drugs in older adults and discontinuation in primary care
  129. Cost outcomes of potentially inappropriate prescribing in middle‐aged adults: A Delphi consensus and cross‐sectional study
  130. Methods for evaluating the benefit and harms of deprescribing in observational research using routinely collected data
  131. GP-delivered medication review of polypharmacy, deprescribing, and patient priorities in older people with multimorbidity in Irish primary care (SPPiRE Study): A cluster randomised controlled trial
  132. A systematic review of the prevalence, determinants, and impact of potentially inappropriate prescribing in middle-aged adults
  133. ‘More of an art than a science’? The development, design and mechanics of the Delphi Technique
  134. Opioid and analgesic utilization in Ireland in 2000 and 2015: A repeated cross‐sectional study
  135. Prescribing cascades in community-dwelling adults: protocol for a systematic review
  136. Blood-Brain Barrier Crossing Renin-Angiotensin Drugs and Cognition in the Elderly: A Meta-Analysis
  137. GPs’ perceptions of their relationship with the pharmaceutical industry: a qualitative study
  138. Prescribing cascades in community-dwelling adults: protocol for a systematic review
  139. Age alone is not a barrier to concurrent chemoradiotherapy for advanced head and neck cancer
  140. Persistence with oral bisphosphonates and denosumab among older adults in primary care in Ireland
  141. Efficacy and safety of sacubitril/valsartan in the treatment of heart failure: protocol for a systematic review incorporating unpublished clinical study reports
  142. Prognostic Significance of Glucocorticoid Receptor Expression in Cancer: A Systematic Review and Meta-Analysis
  143. How many medications do doctors in primary care use? An observational study of the DU90% indicator in primary care in England
  144. Prevalence and predictors of potentially inappropriate prescribing in middle-aged adults: a repeated cross-sectional study
  145. Cognitive decline associated with anticholinergics, benzodiazepines and Z‐drugs: Findings from The Irish Longitudinal Study on Ageing (TILDA)
  146. Factors associated with initiation of bone-health medication among older adults in primary care in Ireland
  147. Persistence with oral bisphosphonates and denosumab among older adults in primary care in Ireland
  148. Aspirin prescribing in cardiovascular disease in middle-aged and older adults in Ireland: findings from The Irish Longitudinal Study on Ageing
  149. Hospital initiation of benzodiazepines and Z-drugs in older adults and discontinuation in primary care
  150. How many medications do doctors in primary care use? An observational study of the DU90% indicator in primary care in England.
  151. Evaluation of the General Practice Pharmacist (GPP) intervention to optimise prescribing in Irish primary care: a non-randomised pilot study
  152. Cognitive decline associated with anticholinergics, benzodiazepines, and Z-drugs: findings from The Irish Longitudinal Study on Ageing (TILDA)
  153. Pharmacists in general practice: a qualitative process evaluation of the General Practice Pharmacist (GPP) study
  154. The Development of an Accreditation Framework for Continuing Education Activities for Pharmacists
  155. High-risk categories for COVID-19 and their distribution by county in Republic of Ireland-evidence from the TILDA study
  156. TILDA report to inform demographics for over 50s in Ireland for COVID-19 crisis
  157. Efficacy and safety of sacubitril/valsartan in the treatment of heart failure: protocol for a systematic review incorporating unpublished clinical study reports
  158. A comparison of contemporary versus older studies of aspirin for primary prevention
  159. Comparing Potentially Inappropriate Prescribing Tools and Their Association With Patient Outcomes
  160. Evaluation of the General Practice Pharmacist (GPP) intervention to optimise prescribing in Irish primary care: a non‐randomised pilot study
  161. Potentially serious alcohol–medication interactions and falls in community-dwelling older adults: a prospective cohort study
  162. Association of Antidepressants With Recurrent, Injurious and Unexplained Falls is Not Explained by Reduced Gait Speed
  163. A comparison of contemporary versus older studies of aspirin for primary prevention
  164. Modification of Potentially Inappropriate Prescribing Following Fall-Related Hospitalizations in Older Adults
  165. Prescriber Variation in Relation to Prescribing Trends within the Preferred Drugs Initiative in Ireland (2012–2015): An Interrupted Time-Series Study Using Latent Curve Models
  166. Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models
  167. Prevalence of potentially inappropriate prescribing in older people in primary care and its association with hospital admission: longitudinal study
  168. Self-report versus electronic medical record recorded healthcare utilisation in older community-dwelling adults: Comparison of two prospective cohort studies
  169. Prescribing Variation in General Practices in England Following a Direct Healthcare Professional Communication on Mirabegron
  170. The PIPc Study—application of indicators of potentially inappropriate prescribing in children (PIPc) to a national prescribing database in Ireland: a cross-sectional prevalence study
  171. Prescribing Variation in General Practices in England Following a Direct Healthcare Professional Communication on Mirabegron
  172. Deprescribing guidelines: An international symposium on development, implementation, research and health professional education
  173. Deprescribing recommendations: An essential consideration for clinical guideline developers
  174. Deprescribing: Future directions for research
  175. Fixed-dose combination antihypertensives and risk of medication errors
  176. Supporting prescribing in Irish primary care: protocol for a non-randomised pilot study of a general practice pharmacist (GPP) intervention to optimise prescribing in primary care
  177. An evaluation of prescribing trends and patterns of claims within the Preferred Drugs Initiative in Ireland (2011–2016): an interrupted time-series study
  178. A narrative review of the safety concerns of deprescribing in older adults and strategies to mitigate potential harms
  179. Potentially inappropriate prescribing and its association with health outcomes in middle-aged people: a prospective cohort study in Ireland
  180. Supporting prescribing in older people with multimorbidity and significant polypharmacy in primary care (SPPiRE): a cluster randomised controlled trial protocol and pilot
  181. Characterizing Potentially Inappropriate Prescribing of Proton Pump Inhibitors in Older People in Primary Care in Ireland from 1997 to 2012
  182. PIPc study: development of indicators of potentially inappropriate prescribing in children (PIPc) in primary care using a modified Delphi technique
  183. Potentially inappropriate prescribing according to STOPP and START and adverse outcomes in community-dwelling older people: a prospective cohort study
  184. Potentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria
  185. Trends and interaction of polypharmacy and potentially inappropriate prescribing in primary care over 15 years in Ireland: a repeated cross-sectional study
  186. Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people
  187. Potentially Inappropriate Medicines and Potential Prescribing Omissions in Older People and Their Association With Health Care Utilization: A Retrospective Cohort Study
  188. Potentially Inappropriate Prescribing and Vulnerability and Hospitalization in Older Community-Dwelling Patients
  189. Prevalence of potentially inappropriate prescribing and prescribing omissions in older Irish adults: findings from The Irish LongituDinal Study on Ageing study (TILDA)
  190. Potentially Inappropriate Prescribing (PIP) and Its Association with Instrumental Activities of Daily Living (IADL) Impairment in Older People