All Stories

  1. Origin and Impact of Nitric Oxide in Pseudomonas aeruginosa Biofilms
  2. Structural Basis of Functional Diversification of the HD-GYP Domain Revealed by the Pseudomonas aeruginosa PA4781 Protein, Which Displays an Unselective Bimetallic Binding Site
  3. How pyridoxal 5′-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state
  4. Screening and In Vitro Testing of Antifolate Inhibitors of Human Cytosolic Serine Hydroxymethyltransferase
  5. Crystal structure of Homo sapiens holo serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), isoform 3, transcript variant 5, 483 aa, at 2.6 ang. resolution
  6. SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
  7. Nitrosylation of c heme in cd1-nitrite reductase is enhanced during catalysis
  8. Distal–proximal crosstalk in the heme binding pocket of the NO sensor DNR
  9. Serine and glycine metabolism in cancer
  10. The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets
  11. Crystal structure of the GGDEF domain of PA1120 (YfiN or TpbB) from Pseudomonas aeruginosa at 2.7 Ang.
  12. p73 keeps metabolic control in balance
  13. Investigating the Allosteric Regulation of YfiN from Pseudomonas aeruginosa: Clues from the Structure of the Catalytic Domain
  14. C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG
  15. The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability
  16. Solvent Accessibility in the Distal Heme Pocket of the Nitrosyl d 1 -Heme Complex of Pseudomonas stutzeri cd 1 Nitrite Reductase
  17. Interactions outside the Boundaries of the Canonical Binding Groove of a PDZ Domain Influence Ligand Binding
  18. Unusual Heme Binding Properties of the Dissimilative Nitrate Respiration Regulator, a Bacterial Nitric Oxide Sensor
  19. Nitrite and Nitrite Reductases: From Molecular Mechanisms to Significance in Human Health and Disease
  20. Nitric oxide synthesis by bacterial cytochrome cd1 nitrite reductases
  21. Cytochromec551
  22. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
  23. Observation of fast release of NO from ferrous d 1 haem allows formulation of a unified reaction mechanism for cytochrome cd 1 nitrite reductases
  24. The catalytic mechanism of Pseudomonas aeruginosa cd 1 nitrite reductase
  25. The Pseudomonas aeruginosa DNR transcription factor: light and shade of nitric oxide-sensing mechanisms
  26. XAS study of the active site of a bacterial heme-sensor
  27. A dramatic conformational rearrangement is necessary for the activation of DNR fromPseudomonas aeruginosa. Crystal structure of wild-type DNR
  28. Nitrite reduction: a ubiquitous function from a pre-aerobic past
  29. The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli
  30. Intramolecular Electron Transfer in Pseudomonas aeruginosa cd1 Nitrite Reductase: Thermodynamics and Kinetics
  31. New insights into the activity of Pseudomonas aeruginosa cd 1 nitrite reductase
  32. NO sensing in Pseudomonas aeruginosa: Structure of the Transcriptional Regulator DNR
  33. Ancient hemes for ancient catalysts
  34. Tyrosine as a redox-active center in electron transfer to ferryl heme in globins
  35. Nitrite controls the release of nitric oxide in Pseudomonas aeruginosa cd1 nitrite reductase
  36. Fast Dissociation of Nitric Oxide from Ferrous Pseudomonas aeruginosa cd1 Nitrite Reductase: A NOVEL OUTLOOK ON THE CATALYTIC MECHANISM
  37. Nitrite Reductases in Denitrification
  38. Histidine and not tyrosine is required for the Peroxide-induced formation of haem to protein cross-linked myoglobin
  39. Critical role of His369 in the reactivity of Pseudomonas aeruginosa cytochrome cd1nitrite reductase with oxygen
  40. N-oxide sensing and denitrification: the DNR transcription factors: Figure 1
  41. 1H-NMR Study of the Effect of Temperature through Reversible Unfolding on the Heme Pocket Molecular Structure and Magnetic Properties of Aplysia limacina Cyano-Metmyoglobin
  42. An Obligatory Intermediate in the Folding Pathway of Cytochrome c 552 from Hydrogenobacter thermophilus
  43. N-oxide sensing in Pseudomonas aeruginosa : expression and preliminary characterization of DNR, an FNR–CRP type transcriptional regulator
  44. NO Production by Pseudomonas aeruginosa cd1 Nitrite Reductase
  45. Folding of Aplysia limacina Apomyoglobin Involves an Intermediate in Common with Other Evolutionarily Distant Globins †
  46. Parallel Pathways in Cytochrome c551 Folding
  47. Electrochemical study of the intermolecular electron transfer to Pseudomonas aeruginosa cytochrome cd1 nitrite reductase
  48. Construction and characterization of a chimeric myoglobin
  49. Expression of a fully functional cd1 nitrite reductase from Pseudomonas aeruginosa in Pseudomonas stutzeri
  50. Cytochrome c551 as a model system for protein folding
  51. Comparative Study of Tyrosine Radicals in Hemoglobin and Myoglobins Treated with Hydrogen Peroxide
  52. Cyanide Binding to cd1 Nitrite Reductase from Pseudomonas aeruginosa: Role of the Active-Site His369 in Ligand Stabilization
  53. Pseudomonas aeruginosa cytochrome C551: probing the role of the hydrophobic patch in electron transfer
  54. Domain Swing Upon His to Ala Mutation in Nitrite Reductase of Pseudomonas aeruginosa
  55. Binding of NO and CO to the d 1 Heme of cd 1 Nitrite Reductase from Pseudomonas aeruginosa †
  56. Snapshots of protein folding. A study on the multiple transition state pathway of cytochrome c551 from Pseudomonas aeruginosa
  57. Kinetics of CO binding and CO photodissociation in Pseudomonas stutzeri cd1 nitrite reductase: probing the role of extended N-termini in fast structural relaxation upon CO photodissociation
  58. Studies on Pseudomonas aeruginosa cd1 nitrite reductase: The association and dissociation reactions of the d1‐heme
  59. A new folding intermediate of apomyoglobin from Aplysia limacina: stepwise formation of a molten globule11Edited by P. E. Wright
  60. Engineering His(E7) Affects the Control of Heme Reactivity in Aplysia limacina Myoglobin
  61. Does picosecond protein dynamics have survival value?
  62. Folding mechanism of Pseudomonas aeruginosa cytochrome c551: role of electrostatic interactions on the hydrophobic collapse and transition state properties
  63. Internal Electron Transfer and Structural Dynamics of cd1 Nitrite Reductase Revealed by Laser CO Photodissociation
  64. Bacterial nitric oxide synthesis
  65. Conformational Changes Occurring upon Reduction and NO Binding in Nitrite Reductase fromPseudomonas aeruginosa†,‡
  66. Equilibrium unfolding of a small bacterial cytochrome, cytochrome c 551 from Pseudomonas aeruginosa
  67. Unfolding of apomyoglobin from Aplysia limacina : the effect of salt and ph on the cooperativity of folding 1 1Edited by P. E. Wright
  68. N-terminal arm exchange is observed in the 2.15 Å crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa
  69. Mutagenesis of nitrite reductase from Pseudomonas aeruginosa: tyrosine‐10 in the c heme domain is not involved in catalysis1
  70. Electron-Transfer Properties of Pseudomonas Aeruginosa [Lys44, Glu64]azurin
  71. Isolation and characterization of the d1 domain of Pseudomonas aeruginosa nitrite reductase
  72. Interactions among residues CD3, E7, E10, and E11 in myoglobins: Attempts to simulate the ligand-binding properties of Aplysia myoglobin
  73. Haemoglobin Engineering: For fun and money
  74. Formate binding to ferric wild type and mutant myoglobins thermodynamic and X-ray crystallographic study
  75. Engineering Ascaris hemoglobin oxygen affinity in sperm whale myoglobin: role of tyrosine B10
  76. Selective oxidation of methionyl residues in the human recombinant secretory leukocyte proteinase inhibitor. Effect on the inhibitor binding properties
  77. Pseudomonas aeruginosa nitrite reductase (or cytochrome oxidase): An overview
  78. Structural and functional characterization of sperm whale myoglobin mutants: Role of arginine (E10) in ligand stabilization
  79. The nitrite reductase gene of Pseudomonas aeruginosa: Effect of growth conditions on the expression and construction of a mutant by gene disruption
  80. Crystal structure of a distal site double mutant of sperm whale myoglobin at 1.6 Å resolution
  81. Selective oxidation of Met-192 in bovine α-chymotrypsin. Effect on catalytic and inhibitor binding properties
  82. Control and recognition of anionic ligands in myoglobin
  83. Analysis of the mechanisms controlling the expression of the L1 ribosomal protein gene in Xenopus laevis
  84. Complementarity of conserved sequence elements present in 28S ribosomal RNA and in ribosomal protein genes of Xenopus laevis and Xenopus tropicalis