All Stories

  1. The pathogenic c.1171A>G (p.Arg391Gly) and c.2359G>A (p.Val787Ile) ABCC6 variants display incomplete penetrance causing pseudoxanthoma elasticum in a subset of individuals
  2. Mutagenic Analysis of the Putative ABCC6 Substrate-Binding Cavity Using a New Homology Model
  3. Riluzole Administration to Rats with Levodopa-Induced Dyskinesia Leads to Loss of DNA Methylation in Neuronal Genes
  4. The pathogenic p.R391G ABCC6 displays incomplete penetrance implying the necessity of an interacting partner for the development of pseudoxanthoma elasticum
  5. Generation of fully functional fluorescent fusion proteins to gain insights into ABCC6 biology
  6. The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP
  7. Nonlinear optical microscopy is a novel tool for the analysis of cutaneous alterations in pseudoxanthoma elasticum
  8. Comparison of inbred mouse strains shows diverse phenotypic outcomes of intervertebral disc aging
  9. Le pyrophosphate : devenir d’un agent anti-calcifiant après transplantation rénale
  10. Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification: A Consensus Statement From the COST Action EuroSoftCalcNet
  11. In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein
  12. Inhibition of DNA methyltransferase leads to increased genomic 5-hydroxymethylcytosine levels in hematopoietic cells
  13. Boosted coupling of ATP hydrolysis to substrate transport upon cooperative estradiol-17-β-D-glucuronide binding in a Drosophila ATP binding cassette type-C transporter
  14. Impact of copper and iron binding properties on the anticancer activity of 8-hydroxyquinoline derived Mannich bases
  15. Tissue-nonspecific alkaline phosphatase: a promising target for pseudoxanthoma elasticum therapy
  16. The ABCC6 Transporter: A New Player in Biomineralization
  17. Oral administration of pyrophosphate inhibits connective tissue calcification
  18. Functional Rescue of ABCC6 Deficiency by 4-Phenylbutyrate Therapy Reduces Dystrophic Calcification in Abcc6–/– Mice
  19. ABCC6-Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation--Brief Report
  20. ABCC6 Is a Basolateral Plasma Membrane Protein
  21. The high turnover Drosophila multidrug resistance-associated protein shares the biochemical features of its human orthologues
  22. The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family
  23. Differential Modulation of the Human Liver Conjugate Transporters MRP2 and MRP3 by Bile Acids and Organic Anions
  24. The role of multidrug transporters in drug availability, metabolism and toxicity
  25. Molecular genetic diagnostic program of multiple endocrine neoplasia type 2A and familial medullary thyroid carcinoma syndromes in Hungary