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  1. The Involvement of RIPK‐3/Caspase‐8 Inhibition and Nrf2/HO‐1 Upregulation in the Protective Effect of Umbelliferone Against Chlorpyrifos‐Induced Pulmonary Toxicity

    Article • Journal of Biochemical and Molecular Toxicology, August 2025, Wiley

    Dr Fares E. M Ali

  2. Combined quercetin with phosphodiesterase inhibitors; sildenafil and pentoxifylline alleviated CCl4-induced chronic hepatic fibrosis: Role of redox-sensitive pathways

    Article • Food and Chemical Toxicology, July 2025, Elsevier

    Dr Fares E. M Ali

  3. Stem Cells Reprogramming in Diabetes Mellitus and Diabetic Complications: Recent Advances

    Article • Current Diabetes Reviews, May 2025, Bentham Science Publishers

    Dr Fares E. M Ali

  4. Crafting cationic lecithmer nanocomposites as promising wagons for brain targeting of cinnamaldehyde: Accentuated neuroprotection via downregulation of Aβ1-42/p-tau crosstalk

    Article • Journal of Drug Delivery Science and Technology, April 2025, Elsevier

    Dr Fares E. M Ali

  5. Neuroprotective effect of diosmin against chlorpyrifos-induced brain intoxication was mediated by regulating PPAR-γ and NF-κB/AP-1 signals

    Article • Food and Chemical Toxicology, November 2024, Elsevier

    Dr Fares E. M Ali

  6. Vicinal diaryl pyrazole with tetrazole/urea scaffolds as selective angiotensin converting enzyme‐1/cyclooxygenase‐2 inhibitors: Design, synthesis, anti‐hypertensive, anti‐fibrotic, and anti‐inflammatory

    Article • Drug Development Research, June 2024, Wiley

    Dr Fares E. M Ali

  7. Mechanism and impact of heavy metal-aluminum (Al) toxicity on male reproduction: Therapeutic approaches with some phytochemicals

    Article • Life Sciences, March 2024, Elsevier

    Dr Fares E. M Ali

  8. The enteroprotective effect of nifuroxazide against methotrexate-induced intestinal injury involves co-activation of PPAR-γ, SIRT1, Nrf2, and suppression of NF-κB and JAK1/STAT3 signals

    Article • International Immunopharmacology, January 2024, Elsevier

    Dr Fares E. M Ali

  9. Lysosomal membrane stabilization by imipramine attenuates gentamicin-induced renal injury: Enhanced LAMP2 expression, down-regulation of cytoplasmic cathepsin D and tBid/cytochrome c/cleaved caspase-3 apoptotic signaling

    Article • International Immunopharmacology, January 2024, Elsevier

    Dr Fares E. M Ali

  10. Renoprotective Effect of Thymoquinone against Streptozotocin-Induced Diabetic Nephropathy: Role of NOX2 and Nrf2 Signals

    Article • Current Molecular Pharmacologye, December 2023, Bentham Science Publishers

    Dr Fares E. M Ali, amal Hofni

  11. Canagliflozin ameliorates ulcerative colitis via regulation of TLR4/MAPK/NF-κB and Nrf2/PPAR-γ/SIRT1 signaling pathways

    Article • European Journal of Pharmacology, December 2023, Elsevier

    Dr Fares E. M Ali

  12. Perindopril Dampens Cd-induced Nephrotoxicity by Suppressing Inflammatory Burden, Ang II/Ang 1–7, and Apoptosis Signaling Pathways

    Article • Biological Trace Element Research, October 2023, Springer Science + Business Media

    Dr Fares E. M Ali

  13. Apocynin abrogates methotrexate-induced nephrotoxicity: role of TLR4/NF-κB-p65/p38-MAPK, IL-6/STAT-3, PPAR-γ, and SIRT1/FOXO3 signaling pathways

    Article • Archives of Pharmacal Research, March 2023, Springer Science + Business Media

    Dr Fares E. M Ali

  14. Exploring the cardioprotective effects of canagliflozin against cisplatin‐induced cardiotoxicity: Role of iNOS/NF‐κB, Nrf2, and Bax/cytochrome C/Bcl‐2 signals

    Article • Journal of Biochemical and Molecular Toxicology, January 2023, Wiley

    Dr Fares E. M Ali

  15. Azilsartan Modulates HMGB1/NF-κB/p38/ERK1/2/JNK and Apoptosis Pathways during Renal Ischemia Reperfusion Injury

    Article • Cells, January 2023, MDPI AG

    Dr Fares E. M Ali

  16. Fasudil Ameliorates Methotrexate-Induced Hepatotoxicity by Modulation of Redox-Sensitive Signals

    Article • Pharmaceuticals, November 2022, MDPI AG

    Dr Fares E. M Ali

  17. Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation

    Article • Molecules, November 2022, MDPI AG

    Dr Fares E. M Ali

  18. Inhibition of NF-kB/IL-6/JAK2/STAT3 Pathway and Epithelial-Mesenchymal Transition in Breast Cancer Cells by Azilsartan

    Article • Molecules, November 2022, MDPI AG

    Dr Fares E. M Ali

  19. Neuroprotective effect of canagliflozin against cisplatin-induced cerebral cortex injury is mediated by regulation of HO-1/PPAR-γ, SIRT1/FOXO-3, JNK/AP-1, TLR4/iNOS, and Ang II/Ang 1–7 signals

    Article • Immunopharmacology and Immunotoxicology, November 2022, Taylor & Francis

    Dr Fares E. M Ali

  20. The involvement of Nrf2/HO-1/cytoglobin and Ang-II/NF-κB signals in the cardioprotective mechanism of lansoprazole against cisplatin-induced heart injury

    Article • Toxicology Mechanisms and Methods, November 2022, Taylor & Francis

    Dr Fares E. M Ali

  21. The importance of natural chalcones in ischemic organ damage: Comprehensive and bioinformatic analysis review

    Article • Journal of Food Biochemistry, July 2022, Wiley

    Dr Fares E. M Ali

  22. RETRACTED ARTICLE: Candesartan Protects Against Cadmium-Induced Hepatorenal Syndrome by Affecting Nrf2, NF-κB, Bax/Bcl-2/Cyt-C, and Ang II/Ang 1–7 Signals

    Article • Biological Trace Element Research, May 2022, Springer Science + Business Media

    Dr Fares E. M Ali

  23. Renoprotective effect of vinpocetine against ischemia/reperfusion injury: Modulation of NADPH oxidase/Nrf2, IKKβ/NF‐κB p65, and cleaved caspase‐3 expressions

    Article • Journal of Biochemical and Molecular Toxicology, March 2022, Wiley

    Dr Fares E. M Ali

  24. Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: Role of Keap‐1/Nrf2/ARE, IL6/STAT‐3, and NF‐κB/AP‐1 signaling pathways

    Article • Phytotherapy Research, December 2021, Wiley

    Dr Fares E. M Ali

  25. Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological analysis

    Article • Life Sciences, November 2021, Elsevier

    Dr Fares E. M Ali

  26. Berberine and/or zinc protect against methotrexate-induced intestinal damage: Role of GSK-3β/NRF2 and JAK1/STAT-3 signaling pathways

    Article • Life Sciences, September 2021, Elsevier

    Dr Fares E. M Ali

  27. Umbelliferone alleviates hepatic ischemia/reperfusion-induced oxidative stress injury via targeting Keap-1/Nrf-2/ARE and TLR4/NF-κB-p65 signaling pathway

    Article • Environmental Science and Pollution Research, July 2021, Springer Science + Business Media

    Dr Fares E. M Ali

  28. Regulation of IL-6/STAT-3/Wnt axis by nifuroxazide dampens colon ulcer in acetic acid-induced ulcerative colitis model: Novel mechanistic insight

    Article • Life Sciences, July 2021, Elsevier

    Dr Fares E. M Ali

  29. Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity

    Article • Life Sciences, June 2021, Elsevier

    Dr Fares E. M Ali

  30. Roflumilast protects from cisplatin-induced testicular toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line. Role of NF-κB-p65, cAMP/PKA and Nrf2/HO-1, NQO1 signaling

    Article • Food and Chemical Toxicology, May 2021, Elsevier

    Dr Fares E. M Ali

  31. Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges

    Article • World Journal of Gastroenterology, April 2021, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr Fares E. M Ali

  32. Trans-ferulic acid ameliorates cisplatin-induced testicular damage via suppression of TLR4, P38-MAPK, and ERK1/2 signaling pathways

    Article • Environmental Science and Pollution Research, April 2021, Springer Science + Business Media

    Dr Fares E. M Ali

  33. Role of TLR-4/IL-6/TNF-α, COX-II and eNOS/iNOS pathways in the impact of carvedilol against hepatic ischemia reperfusion injury

    Article • Human & Experimental Toxicology, March 2021, SAGE Publications

    Dr Fares E. M Ali

  34. Nephroprotective effect of umbelliferone against cisplatin‐induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1/FOXO‐3, and NF‐ k B‐p65 signaling pathways

    Article • Journal of Biochemical and Molecular Toxicology, February 2021, Wiley

    Dr Fares E. M Ali

  35. Pretreatment with Coenzyme Q10 Combined with Aescin Protects against Sepsis-Induced Acute Lung Injury

    Article • Cells Tissues Organs, January 2021, Karger Publishers

    Dr Fares E. M Ali

  36. The Impact of Royal Jelly against Hepatic Ischemia/Reperfusion-Induced Hepatocyte Damage in Rats: The Role of Cytoglobin, Nrf-2/HO-1/COX-4, and P38-MAPK/NF-κB-p65/TNF-α Signaling Pathways

    Article • Current Molecular Pharmacologye, December 2020, Bentham Science Publishers

    Dr Fares E. M Ali, Osama Elsayed

  37. Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-κB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways

    Article • Environmental Science and Pollution Research, October 2020, Springer Science + Business Media

    Dr Fares E. M Ali

  38. Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways

    Article • Immunopharmacology and Immunotoxicology, August 2020, Taylor & Francis

    Dr Fares E. M Ali

  39. Ursodeoxycholic acid abrogates gentamicin-induced hepatotoxicity in rats: Role of NF-κB-p65/TNF-α, Bax/Bcl-xl/Caspase-3, and eNOS/iNOS pathways

    Article • Life Sciences, August 2020, Elsevier

    Dr Fares E. M Ali

  40. Novel Water-Soluble Lubricant for the Preparation of Tiemonium Methylsulfate Fast-Dissolving Tablets

    Article • Journal of Drug Delivery Science and Technology, August 2020, Elsevier

    Dr Fares E. M Ali, Prof. Gamal Zayed

  41. Rebamipide potentially mitigates methotrexate‐induced nephrotoxicity via inhibition of oxidative stress and inflammation: a molecular and histochemical study

    Article • The Anatomical Record, June 2020, Wiley

    Dr Fares E. M Ali

  42. Diosmin enhances the anti-angiogenic activity of sildenafil and pentoxifylline against hepatopulmonary syndrome via regulation of TNF-α/VEGF, IGF-1/PI3K/AKT, and FGF-1/ANG-2 signaling pathways

    Article • European Journal of Pharmacology, April 2020, Elsevier

    Dr Fares E. M Ali

  43. Perindopril Ameliorates Hepatic Ischemia Reperfusion Injury Via Regulation of NF‐κB‐p65/TLR‐4, JAK1/STAT‐3, Nrf‐2, and PI3K/Akt/mTOR Signaling Pathways

    Article • The Anatomical Record, November 2019, Wiley

    Dr Fares E. M Ali

  44. Coenzyme Q10 protects hepatocytes from ischemia reperfusion-induced apoptosis and oxidative stress via regulation of Bax/Bcl-2/PUMA and Nrf-2/FOXO-3/Sirt-1 signaling pathways

    Article • Tissue and Cell, October 2019, Elsevier

    Dr Fares E. M Ali

  45. Hepatoprotective effects of diosmin and/or sildenafil against cholestatic liver cirrhosis: The role of Keap-1/Nrf-2 and P38-MAPK/NF-κB/iNOS signaling pathway

    Article • Food and Chemical Toxicology, October 2018, Elsevier

    Dr Fares E. M Ali

  46. Reno-protective effects of ursodeoxycholic acid against gentamicin-induced nephrotoxicity through modulation of NF-κB, eNOS and caspase-3 expressions

    Article • Cell and Tissue Research, August 2018, Springer Science + Business Media

    Dr Fares E. M Ali

  47. Targeting Keap-1/Nrf-2 pathway and cytoglobin as a potential protective mechanism of diosmin and pentoxifylline against cholestatic liver cirrhosis

    Article • Life Sciences, August 2018, Elsevier

    Dr Fares E. M Ali

  48. Protective Effects of Quercetin and Ursodeoxycholic Acid on Hepatic Ischemia-Reperfusion Injury in Rats

    Article • Clinical Pharmacology & Biopharmaceutics, January 2015, OMICS Publishing Group

    Dr Fares E. M Ali