All Stories

  1. Image-based modeling of vascular organization to evaluate anti-angiogenic therapy
  2. Contribution of Adventitia-Derived Stem and Progenitor Cells to New Vessel Formation in Tumors
  3. Extracellular Matrix in the Tumor Microenvironment and Its Impact on Cancer Therapy
  4. Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells
  5. Inhibition of platelet GPVI induces intratumor hemorrhage and increases efficacy of chemotherapy in mice
  6. The Best for the Most Important: Maintaining a Pristine Proteome in Stem and Progenitor Cells
  7. Restriction of drug transport by the tumor environment
  8. LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy
  9. VEGF-ablation therapy reduces drug delivery and therapeutic response in ECM-dense tumors
  10. Inhibition of Lysyl Oxidases Improves Drug Diffusion and Increases Efficacy of Cytotoxic Treatment in 3D Tumor Models
  11. Four different synthetic peptides of proteolipid protein induce a distinct antibody response in MP4-induced experimental autoimmune encephalomyelitis
  12. Phenotypic Diversity and Plasticity in Circulating Neutrophil Subpopulations in Cancer
  13. Induction of Antagonistic Soluble Decoy Receptor Tyrosine Kinases by Intronic PolyA Activation
  14. Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung
  15. Selective Killing of Tumor Neovasculature Paradoxically Improves Chemotherapy Delivery to Tumors
  16. Inhibition of Neovascularization to Simultaneously Ameliorate Graft-vs-Host Disease and Decrease Tumor Growth
  17. Rapid Chemotherapy-Induced Acute Endothelial Progenitor Cell Mobilization: Implications for Antiangiogenic Drugs as Chemosensitizing Agents
  18. Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo
  19. Improved tumor imaging and therapy via i.v. IgG–mediated time-sequential modulation of neonatal Fc receptor
  20. Improved tumor imaging and therapy via i.v. IgG–mediated time-sequential modulation of neonatal Fc receptor
  21. Selective Alpha-Particle Mediated Depletion of Tumor Vasculature with Vascular Normalization
  22. A versatile esterase fromBacillus subtilis: Cloning, expression, characterization, and its application in biocatalysis
  23. Induction of Complete Regressions of Oncogene-induced Breast Tumors in Mice
  24. A New Route to Protected Acyloins and Their Enzymatic Resolution with Lipases
  25. Directed Evolution of Lipases and Esterases
  26. A Molecular Mechanism of Enantiorecognition of Tertiary Alcohols by Carboxylesterases
  27. Mutations in Distant Residues Moderately Increase the Enantioselectivity of Pseudomonas fluorescens Esterase towards Methyl 3Bromo-2-methylpropanoate and Ethyl 3Phenylbutyrate
  28. Fluorophoric Assay for the High-Throughput Determination of Amidase Activity
  29. Esterases from Bacillus subtilis and B. stearothermophilus share high sequence homology but differ substantially in their properties
  30. Activity of Lipases and Esterases towards Tertiary Alcohols: Insights into Structure���Function Relationships
  31. Screening of Commercial Hydrolases for the Degradation of Ochratoxin A
  32. Lipase-Catalyzed Resolution of Ibuprofen
  33. Highly efficient double enantioselection by lipase-catalyzed transesterification of (R,S)-carboxylic acid vinyl esters with (RS)-1-phenylethanol
  34. The Use of Vinyl Esters Significantly Enhanced Enantioselectivities and Reaction Rates in Lipase-Catalyzed Resolutions of Arylaliphatic Carboxylic Acids
  35. Directed Evolution of an Esterase from Pseudomonas fluorescens. Random Mutagenesis by Error-Prone PCR or a Mutator Strain and Identification of Mutants Showing Enhanced Enantioselectivity by a Resorufin-Based Fluorescence Assay