All Stories

  1. A bio-guided approach for the development of a chestnut-based proanthocyanidin-enriched nutraceutical with potential anti-gastritis properties

    Article • Pharmacological Research, August 2018, Elsevier

    Dr Emma De Fabiani

  2. HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning

    Article • Nature Communications, July 2017, Nature

    Dr Emma De Fabiani

  3. Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases

    Article • International Journal of Obesity, October 2016, Nature

    Dr Emma De Fabiani

  4. Strawberry tannins inhibit IL-8 secretion in a cell model of gastric inflammation

    Article • Pharmacological Research, July 2016, Elsevier

    Dr Emma De Fabiani

  5. Targeting lipid metabolism to starve and stop cancer cells

    Article • European Journal of Lipid Science and Technology, June 2015, Wiley

    Dr Emma De Fabiani

  6. Olive oil phenolic extract regulates interleukin-8 expression by transcriptional and posttranscriptional mechanisms in Caco-2 cells

    Article • Molecular Nutrition & Food Research, April 2015, Wiley

    Dr Emma De Fabiani

  7. Lack of Sterol Regulatory Element Binding Factor-1c Imposes Glial Fatty Acid Utilization Leading to Peripheral Neuropathy

    Article • Cell Metabolism, April 2015, Elsevier

    Dr Emma De Fabiani

  8. Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function

    Article • Current Genomics, January 2015, Bentham Science Publishers

    Dr Emma De Fabiani

  9. Lipids in the nervous system: From biochemistry and molecular biology to patho-physiology

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, January 2015, Elsevier

    Dr Emma De Fabiani

  10. Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy

    Article • The Journal of Steroid Biochemistry and Molecular Biology, September 2014, Elsevier

    Dr Emma De Fabiani

  11. Lipids IN the brain: Crossing the “insurmountable” barrier for a fatty, happy life

    Article • European Journal of Lipid Science and Technology, August 2014, Wiley

    Dr Emma De Fabiani

  12. The sirtuin class of histone deacetylases: Regulation and roles in lipid metabolism

    Article • IUBMB Life, February 2014, Wiley

    Dr Emma De Fabiani

  13. LT175 Is a Novel PPARα/γ Ligand with Potent Insulin-sensitizing Effects and Reduced Adipogenic Properties

    Article • Journal of Biological Chemistry, January 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Emma De Fabiani

  14. Brown-like adipocytes colonizing white fat: A (r)evolutionary way to fight obesity?

    Article • European Journal of Lipid Science and Technology, November 2012, Wiley

    Dr Emma De Fabiani

  15. Linking epigenetics to lipid metabolism: Focus on histone deacetylases

    Article • Molecular Membrane Biology, October 2012, Taylor & Francis

    Dr Emma De Fabiani

  16. Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

    Article • Diabetes, October 2012, American Diabetes Association

    Dr Emma De Fabiani

  17. The complex world of sterols: Many threads find their way through cells

    Article • European Journal of Lipid Science and Technology, June 2012, Wiley

    Dr Emma De Fabiani

  18. Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation

    Article • Journal of Lipid Research, December 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Emma De Fabiani

  19. Spotlights on Lipid Science from the 36th FEBS Congress, June 25-30, 2011, Torino, Italy

    Article • European Journal of Lipid Science and Technology, November 2011, Wiley

    Dr Emma De Fabiani

  20. The true story of palmitoleic acid: Between myth and reality

    Article • European Journal of Lipid Science and Technology, July 2011, Wiley

    Dr Emma De Fabiani

  21. Oxysterols: Swiss army knife in a cell's toolbox

    Article • European Journal of Lipid Science and Technology, August 2010, Wiley

    Dr Emma De Fabiani

  22. Enterodiol and Enterolactone Modulate the Immune Response by Acting on Nuclear Factor-κB (NF-κB) Signaling

    Article • Journal of Agricultural and Food Chemistry, June 2010, American Chemical Society (ACS)

    Dr Emma De Fabiani

  23. When Food Meets Man: the Contribution of Epigenetics to Health

    Article • Nutrients, May 2010, MDPI AG

    Dr Emma De Fabiani

  24. Olive Oil Phenols Modulate the Expression of Metalloproteinase 9 in THP-1 Cells by Acting on Nuclear Factor-κB Signaling

    Article • Journal of Agricultural and Food Chemistry, February 2010, American Chemical Society (ACS)

    Dr Emma De Fabiani

  25. Sterol–Protein Interactions in Cholesterol and Bile Acid Synthesis

    Article • January 2010, Springer Science + Business Media

    Dr Emma De Fabiani

  26. Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling

    Article • Neuroscience, December 2009, Elsevier

    Dr Emma De Fabiani

  27. Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors

    Article • Journal of Medicinal Chemistry, September 2009, American Chemical Society (ACS)

    Dr Emma De Fabiani

  28. Disruption of the gene encoding 3β-hydroxysterol Δ14-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis

    Article • FEBS Journal, September 2008, Wiley

    Dr Emma De Fabiani

  29. Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis

    Article • Clinica Chimica Acta, September 2008, Elsevier

    Dr Emma De Fabiani

  30. The pharmacological exploitation of cholesterol 7α-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol

    Article • Pharmacology & Therapeutics, December 2007, Elsevier

    Dr Emma De Fabiani

  31. Lipid sensing and lipid sensors

    Article • Cellular and Molecular Life Sciences, September 2007, Springer Science + Business Media

    Dr Emma De Fabiani

  32. Insights in the regulation of cholesterol 7α-hydroxylase gene reveal a target for modulating bile acid synthesis

    Article • Hepatology, September 2007, Wiley

    Dr Emma De Fabiani

  33. Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease

    Article • Clinica Chimica Acta, July 2007, Elsevier

    Dr Emma De Fabiani

  34. Age-related changes in bile acid synthesis and hepatic nuclear receptor expression

    Article • European Journal of Clinical Investigation, June 2007, Wiley

    Dr Emma De Fabiani

  35. Minor Components of Olive Oil Modulate Proatherogenic Adhesion Molecules Involved in Endothelial Activation

    Article • Journal of Agricultural and Food Chemistry, May 2006, American Chemical Society (ACS)

    Dr Emma De Fabiani

  36. Decreased hepatic expression of PPAR-gamma coactivator-1 in cholesterol cholelithiasis

    Article • European Journal of Clinical Investigation, March 2006, Wiley

    Dr Emma De Fabiani

  37. A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis

    Article • Clinica Chimica Acta, May 2005, Elsevier

    Dr Emma De Fabiani

  38. Bile acid signaling to the nucleus: finding new connections in the transcriptional regulation of metabolic pathways

    Article • Biochimie, November 2004, Elsevier

    Dr Emma De Fabiani

  39. Lipid-activated nuclear receptors: from gene transcription to the control of cellular metabolism

    Article • European Journal of Lipid Science and Technology, July 2004, Wiley

    Dr Emma De Fabiani

  40. LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport

    Article • Biochemical Society Transactions, February 2004, Portland Press Ltd.

    Dr Emma De Fabiani

  41. Coordinated Control of Cholesterol Catabolism to Bile Acids and of Gluconeogenesis via a Novel Mechanism of Transcription Regulation Linked to the Fasted-to-fed Cycle

    Article • Journal of Biological Chemistry, July 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Emma De Fabiani

  42. Suppression of bile acid synthesis, but not of hepatic cholesterol 7α-hydroxylase expression, by obstructive cholestasis in humans

    Article • Hepatology, August 2001, Wiley

    Dr Emma De Fabiani

  43. The Negative Effects of Bile Acids and Tumor Necrosis Factor-alpha on the Transcription of Cholesterol 7alpha -Hydroxylase Gene (CYP7A1) Converge to Hepatic Nuclear Factor-4. A NOVEL MECHANISM OF FEEDBACK REGULATION OF BILE ACID SYNTHESIS MEDIATED BY N...

    Article • Journal of Biological Chemistry, June 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Emma De Fabiani

  44. Identification and characterization of cis-acting elements conferring insulin responsiveness on hamster cholesterol 7α-hydroxylase gene promoter

    Article • Biochemical Journal, April 2000, Portland Press Ltd.

    Dr Emma De Fabiani

  45. Regulation of the Hamster Cholesterol 7α-Hydroxylase Gene (CYP7A): Prevalence of Negative over Positive Transcriptional Control

    Article • Biochemical and Biophysical Research Communications, September 1996, Elsevier

    Dr Emma De Fabiani

  46. Plasma lipoproteins and cholesterol metabolism in Yoshida rats: An animal model of spontaneous hyperlipemia

    Article • Life Sciences, January 1992, Elsevier

    Dr Emma De Fabiani

  47. Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes. II

    Article • Chemistry and Physics of Lipids, January 1991, Elsevier

    Dr Emma De Fabiani

  48. Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes

    Article • Chemistry and Physics of Lipids, October 1989, Elsevier

    Dr Emma De Fabiani

  49. The effect of etofibrate on cholesterol and bile acid metabolism in the hamster

    Article • Pharmacological Research, September 1989, Elsevier

    Dr Emma De Fabiani

  50. Effect of tauroursodeoxycholate feeding, with or without taurine supplementation on hepatic bile acids and cholesterol metabolism in the hamster

    Article • Pharmacological Research Communications, May 1987, Elsevier

    Dr Emma De Fabiani