All Stories

  1. Electron microscopic analysis of the mouse and human alveolar epithelial glycocalyx using high pressure freezing and freeze substitution

    Article • AJP Cell Physiology, July 2026, American Physiological Society

    PhD Elena Lopez-Rodriguez

  2. Opening the Black Box: Reflections from the AJP-Lung Early Career Editorial Fellows

    Article • AJP Lung Cellular and Molecular Physiology, July 2026, American Physiological Society

    Dr Kent Willis, PhD Elena Lopez-Rodriguez

  3. Alveolar type 2 cell LRP1 is needed for surfactant phospholipid metabolism and pulmonary function in mice

    Article • Journal of Lipid Research, May 2026, Elsevier

    PhD Elena Lopez-Rodriguez

  4. Altered cholesterol immunometabolism activates the macrophage NLRP3-inflammasome in lung fibrosis

    Article • American Journal of Respiratory Cell and Molecular Biology, February 2026, Oxford University Press (OUP)

    PhD Elena Lopez-Rodriguez

  5. Thermodynamic Insights into Native Pulmonary Surfactant Films: Elastic Compression Modulus and Energy Dissipation under Cyclic Deformation

    Article • Langmuir, February 2026, American Chemical Society (ACS)

    PhD Elena Lopez-Rodriguez

  6. Cholesterol-mediated inflammation activation in alveolar macrophages

    Article • BMC Biology, December 2025, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  7. Mechanical strain exacerbates Pseudomonas infection in an organoid-based pneumonia-on-a-chip model

    Article • Journal of Clinical Investigation, November 2025, American Society for Clinical Investigation

    PhD Elena Lopez-Rodriguez

  8. Neutrophil-chemoattractant CXCL5 increases lung barrier permeability in acute lung injury

    Article • Mucosal Immunology, October 2025, Elsevier

    PhD Elena Lopez-Rodriguez

  9. Cell Surface RNA Expression Modulates Alveolar Epithelial Function

    Article • American Journal of Respiratory Cell and Molecular Biology, September 2025, American Thoracic Society

    PhD Elena Lopez-Rodriguez

  10. Enzymatic Modulation of the Pulmonary Glycocalyx Enhances Susceptibility to Streptococcus pneumoniae

    Article • American Journal of Respiratory Cell and Molecular Biology, December 2024, American Thoracic Society

    PhD Elena Lopez-Rodriguez

  11. Comparative electron microscopic visualization of the lung alveolar epithelial glycocalyx with different staining and labeling methods

    Article • Journal of Anatomy, September 2024, Wiley

    PhD Elena Lopez-Rodriguez

  12. Characterization of Commercially Available Human Primary Alveolar Epithelial Cells

    Article • American Journal of Respiratory Cell and Molecular Biology, May 2024, American Thoracic Society

    PhD Elena Lopez-Rodriguez

  13. Multivalent, calcium-independent binding of surfactant protein A and D to sulfated glycosaminoglycans of the alveolar epithelial glycocalyx

    Article • AJP Lung Cellular and Molecular Physiology, May 2024, American Physiological Society

    PhD Elena Lopez-Rodriguez

  14. Enzymatic modulation of the pulmonary glycocalyx alters susceptibility toStreptococcus pneumoniae

    Article • January 2024, Cold Spring Harbor Laboratory Press

    PhD Elena Lopez-Rodriguez

  15. The unremarkable alveolar epithelial glycocalyx: a thorium dioxide-based electron microscopic comparison after heparinase or pneumolysin treatment

    Article • Histochemistry and Cell Biology, June 2023, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  16. Ten simple rules for implementing open and reproducible research practices after attending a training course

    Article • PLoS Computational Biology, January 2023, PLOS

    PhD Elena Lopez-Rodriguez

  17. Resting time after phorbol 12-myristate 13-acetate in THP-1 derived macrophages provides a non-biased model for the study of NLRP3 inflammasome

    Article • Frontiers in Immunology, December 2022, Frontiers

    PhD Elena Lopez-Rodriguez

  18. Human alveolar progenitors generate dual lineage bronchioalveolar organoids

    Article • Communications Biology, August 2022, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  19. The ultrastructural heterogeneity of lung surfactant revealed by serial section electron tomography: insights into the 3-D architecture of human tubular myelin

    Article • AJP Lung Cellular and Molecular Physiology, June 2022, American Physiological Society

    PhD Elena Lopez-Rodriguez

  20. Rescue from Pseudomonas aeruginosa Airway Infection via Stem Cell Transplantation

    Article • Molecular Therapy, March 2021, Elsevier

    PhD Elena Lopez-Rodriguez

  21. Improved Alveolar Dynamics and Structure After Alveolar Epithelial Type II Cell Transplantation in Bleomycin Induced Lung Fibrosis

    Article • Frontiers in Medicine, February 2021, Frontiers

    PhD Elena Lopez-Rodriguez

  22. Metabolic Glycoengineering Enables the Ultrastructural Visualization of Sialic Acids in the Glycocalyx of the Alveolar Epithelial Cell Line hAELVi

    Article • Frontiers in Bioengineering and Biotechnology, January 2021, Frontiers

    PhD Elena Lopez-Rodriguez

  23. Mechanical ventilation-induced alterations of intracellular surfactant pool and blood–gas barrier in healthy and pre-injured lungs

    Article • Histochemistry and Cell Biology, November 2020, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  24. Pulmonary glycogen deficiency as a new potential cause of respiratory distress syndrome

    Article • Human Molecular Genetics, November 2020, Oxford University Press (OUP)

    PhD Elena Lopez-Rodriguez

  25. Hidden Microatelectases Increase Vulnerability to Ventilation-Induced Lung Injury

    Article • Frontiers in Physiology, September 2020, Frontiers

    PhD Elena Lopez-Rodriguez

  26. Corrigendum: Alveolar Dynamics and Beyond – the Importance of Surfactant Protein C and Cholesterol in Lung Homeostasis and Fibrosis

    Article • Frontiers in Physiology, September 2020, Frontiers

    PhD Elena Lopez-Rodriguez

  27. Reply to: Comments on “Air Space Distension Precedes Spontaneous Fibrotic Remodeling and Impaired Cholesterol Metabolism in the Absence of Surfactant Protein C”

    Article • American Journal of Respiratory Cell and Molecular Biology, September 2020, American Thoracic Society

    PhD Elena Lopez-Rodriguez

  28. Spermidine supplementation and voluntary activity differentially affect obesity-related structural changes in the mouse lung

    Article • AJP Lung Cellular and Molecular Physiology, August 2020, American Physiological Society

    PhD Elena Lopez-Rodriguez

  29. Alveolar Dynamics and Beyond – The Importance of Surfactant Protein C and Cholesterol in Lung Homeostasis and Fibrosis

    Article • Frontiers in Physiology, May 2020, Frontiers

    PhD Elena Lopez-Rodriguez

  30. On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx

    Article • International Journal of Molecular Sciences, April 2020, MDPI AG

    PhD Elena Lopez-Rodriguez

  31. In Vitro Functional and Structural Characterization of A Synthetic Clinical Pulmonary Surfactant with Enhanced Resistance to Inhibition

    Article • Scientific Reports, January 2020, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  32. Air Space Distension Precedes Spontaneous Fibrotic Remodeling and Impaired Cholesterol Metabolism in the Absence of Surfactant Protein C

    Article • American Journal of Respiratory Cell and Molecular Biology, January 2020, American Thoracic Society

    PhD Elena Lopez-Rodriguez

  33. Surfactant Protein B Deficiency Induced High Surface Tension: Relationship between Alveolar Micromechanics, Alveolar Fluid Properties and Alveolar Epithelial Cell Injury

    Article • International Journal of Molecular Sciences, August 2019, MDPI AG

    PhD Elena Lopez-Rodriguez

  34. Effective hematopoietic stem cell-based gene therapy in a murine model of hereditary pulmonary alveolar proteinosis

    Article • Haematologica, July 2019, Ferrata Storti Foundation (Haematologica)

    PhD Elena Lopez-Rodriguez

  35. Flow cytometric analysis of the leukocyte landscape during bleomycin-induced lung injury and fibrosis in the rat

    Article • AJP Lung Cellular and Molecular Physiology, July 2019, American Physiological Society

    PhD Elena Lopez-Rodriguez

  36. Voluntary Activity Modulates Sugar-Induced Elastic Fiber Remodeling in the Alveolar Region of the Mouse Lung

    Article • International Journal of Molecular Sciences, May 2019, MDPI AG

    PhD Elena Lopez-Rodriguez

  37. The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis

    Article • Thorax, May 2019, BMJ

    PhD Elena Lopez-Rodriguez

  38. Voluntary Activity Modulates Sugar-Induced Mechanical and Structural Changes of the Lung

    Article • February 2019, Thieme Publishing Group

    PhD Elena Lopez-Rodriguez

  39. Protein and lipid fingerprinting of native-like membrane complexes by combining TLC and protein electrophoresis

    Article • Journal of Lipid Research, February 2019, Elsevier

    PhD Elena Lopez-Rodriguez

  40. Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis

    Article • Laboratory Investigation, January 2019, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  41. How alveoli (small balloon-like air spaces) behave during lung injury

    Article • American Journal of Respiratory Cell and Molecular Biology, December 2018, American Thoracic Society

    PhD Elena Lopez-Rodriguez

  42. An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages

    Article • Scientific Reports, November 2018, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  43. Inhibition and counterinhibition of Surfacen, a clinical lung surfactant of natural origin

    Article • PLOS One, September 2018, PLOS

    PhD Elena Lopez-Rodriguez

  44. iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice

    Article • Stem Cell Reports, September 2018, Elsevier

    PhD Elena Lopez-Rodriguez

  45. Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model

    Article • AJP Lung Cellular and Molecular Physiology, August 2017, American Physiological Society

    PhD Elena Lopez-Rodriguez

  46. Aging exacerbates acute lung injury-induced changes of the air-blood barrier, lung function, and inflammation in the mouse

    Article • AJP Lung Cellular and Molecular Physiology, January 2017, American Physiological Society

    PhD Elena Lopez-Rodriguez

  47. Toll-like receptor 4 activation attenuates profibrotic response in control lung fibroblasts but not in fibroblasts from patients with IPF

    Article • AJP Lung Cellular and Molecular Physiology, January 2017, American Physiological Society

    PhD Elena Lopez-Rodriguez

  48. Lung surfactant metabolism: early in life, early in disease and target in cell therapy

    Article • Cell and Tissue Research, October 2016, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  49. Human Pulmonary Surfactant Protein SP-A1 Provides Maximal Efficiency of Lung Interfacial Films

    Article • Biophysical Journal, August 2016, Elsevier

    PhD Elena Lopez-Rodriguez

  50. Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo

    Article • AJP Lung Cellular and Molecular Physiology, June 2016, American Physiological Society

    PhD Elena Lopez-Rodriguez

  51. Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model

    Article • AJP Lung Cellular and Molecular Physiology, July 2015, American Physiological Society

    PhD Elena Lopez-Rodriguez

  52. Alveolar Derecruitment and Collapse Induration as Crucial Mechanisms in Lung Injury and Fibrosis

    Article • American Journal of Respiratory Cell and Molecular Biology, February 2015, American Thoracic Society

    PhD Elena Lopez-Rodriguez

  53. Structure-function relationships in pulmonary surfactant membranes: From biophysics to therapy

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, June 2014, Elsevier

    PhD Elena Lopez-Rodriguez

  54. Transient Exposure of Pulmonary Surfactant to Hyaluronan Promotes Structural and Compositional Transformations into a Highly Active State

    Article • Journal of Biological Chemistry, October 2013, Elsevier

    PhD Elena Lopez-Rodriguez

  55. Clinical and biological role of secretory phospholipase A2 in acute respiratory distress syndrome infants

    Article • Critical Care, July 2013, Springer Science + Business Media

    PhD Elena Lopez-Rodriguez

  56. Interfacial behavior and structural properties of a clinical lung surfactant from porcine source

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, November 2012, Elsevier

    PhD Elena Lopez-Rodriguez

  57. Exposure to Polymers Reverses Inhibition of Pulmonary Surfactant by Serum, Meconium, or Cholesterol in the Captive Bubble Surfactometer

    Article • Biophysical Journal, October 2012, Elsevier

    PhD Elena Lopez-Rodriguez

  58. Meconium Impairs Pulmonary Surfactant by a Combined Action of Cholesterol and Bile Acids

    Article • Biophysical Journal, February 2011, Elsevier

    PhD Elena Lopez-Rodriguez