All Stories

  1. Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses

    Article • PLoS Pathogens, February 2023, PLOS

    Dr. El-Sayed M. Abdel-Whab

  2. Evidence for Different Virulence Determinants and Host Response after Infection of Turkeys and Chickens with Highly Pathogenic H7N1 Avian Influenza Virus

    Article • Journal of Virology, September 2022, ASM Journals

    Dr. El-Sayed M. Abdel-Whab

  3. Genetic Determinants for Virulence and Transmission of the Panzootic Avian Influenza Virus H5N8 Clade 2.3.4.4 in Pekin Ducks

    Article • Journal of Virology, July 2022, ASM Journals

    Dr. El-Sayed M. Abdel-Whab

  4. Isolation of Genetically Diverse H5N8 Avian Influenza Viruses in Poultry in Egypt, 2019–2021

    Article • Viruses, June 2022, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  5. Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells

    Article • Journal of Virology, September 2021, ASM Journals

    Dr. El-Sayed M. Abdel-Whab

  6. Preferential Selection and Contribution of Non-Structural Protein 1 (NS1) to the Efficient Transmission of Panzootic Avian Influenza H5N8 Virus Clades 2.3.4.4A and B in Chickens and Ducks

    Article • Journal of Virology, August 2021, ASM Journals

    Dr. El-Sayed M. Abdel-Whab

  7. Insights into SARS-CoV-2 evolution, potential antivirals, and vaccines

    Article • Virology, June 2021, Elsevier

    Dr. El-Sayed M. Abdel-Whab

  8. A Semiquantitative Scoring System for Histopathological and Immunohistochemical Assessment of Lesions and Tissue Tropism in Avian Influenza

    Article • Viruses, May 2021, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  9. Light Sheet Microscopy-Assisted 3D Analysis of SARS-CoV-2 Infection in the Respiratory Tract of the Ferret Model

    Article • Viruses, March 2021, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  10. Preferential selection and contribution of non-structural protein 1 (NS1) to the efficient transmission of the panzootic avian influenza H5N8 2.3.4.4 clades A and B viruses in chickens and ducks

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Dr. El-Sayed M. Abdel-Whab

  11. The role of glycosylation in the N-terminus of the hemagglutinin of a unique H4N2 with a natural polybasic cleavage site in virus fitness in vitro and in vivo

    Article • Virulence, February 2021, Taylor & Francis

    Dr. El-Sayed M. Abdel-Whab

  12. The C-terminus of non-structural protein 1 (NS1) in H5N8 clade 2.3.4.4 avian influenza virus affects virus fitness in human cells and virulence in mice

    Article • Emerging Microbes & Infections, January 2021, Taylor & Francis

    Dr. El-Sayed M. Abdel-Whab

  13. Non-basic amino acids in the hemagglutinin proteolytic cleavage site of a European H9N2 avian influenza virus modulate virulence in turkeys

    Article • Scientific Reports, December 2020, Springer Science + Business Media

    Dr. El-Sayed M. Abdel-Whab

  14. 3D reconstruction of SARS-CoV-2 infection in ferrets emphasizes focal infection pattern in the upper respiratory tract

    Article • October 2020, Cold Spring Harbor Laboratory Press

    Dr. El-Sayed M. Abdel-Whab

  15. Immunization with Plant-Derived Multimeric H5 Hemagglutinins Protect Chicken against Highly Pathogenic Avian Influenza Virus H5N1

    Article • Vaccines, October 2020, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  16. Genetic incompatibilities and reduced transmission in chickens may limit the evolution of reassortants between H9N2 and panzootic H5N8 clade 2.3.4.4 avian influenza virus showing high virulence for mammals

    Article • Virus Evolution, July 2020, Oxford University Press (OUP)

    Dr. El-Sayed M. Abdel-Whab

  17. Evidence for SARS-CoV-2 Infection of Animal Hosts

    Article • Pathogens, June 2020, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  18. Insertion of Basic Amino Acids in the Hemagglutinin Cleavage Site of H4N2 Avian Influenza Virus (AIV)—Reduced Virus Fitness in Chickens is Restored by Reassortment with Highly Pathogenic H5N1 AIV

    Article • International Journal of Molecular Sciences, March 2020, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  19. Insertion of Basic Amino Acids in the Hemagglutinin Cleavage Site of H4N2 Avian Influenza Virus (AIV) Reduced Virus Fitness in Chickens which is Restored by Reassortment with Highly Pathogenic H5N1 AIV

    Article • February 2020, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  20. Variable impact of the hemagglutinin polybasic cleavage site on virulence and pathogenesis of avian influenza H7N7 virus in chickens, turkeys and ducks

    Article • Scientific Reports, August 2019, Springer Science + Business Media

    Dr. El-Sayed M. Abdel-Whab

  21. Virulence of three European highly pathogenic H7N1 and H7N7 avian influenza viruses in Pekin and Muscovy ducks

    Article • BMC Veterinary Research, May 2019, Springer Science + Business Media

    Dr. El-Sayed M. Abdel-Whab

  22. Orthomyxoviruses

    Article • January 2019, Springer Science + Business Media

    Dr. El-Sayed M. Abdel-Whab

  23. A viral race for primacy: co-infection of a natural pair of low and highly pathogenic H7N7 avian influenza viruses in chickens and embryonated chicken eggs

    Article • Emerging Microbes & Infections, December 2018, Taylor & Francis

    Dr. El-Sayed M. Abdel-Whab

  24. Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview

    Article • Viruses, September 2018, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  25. A Dual Motif in the Hemagglutinin of H5N1 Goose/Guangdong-Like Highly Pathogenic Avian Influenza Virus Strains Is Conserved from Their Early Evolution and Increases both Membrane Fusion pH and Virulence

    Article • Journal of Virology, June 2018, ASM Journals

    Dr. El-Sayed M. Abdel-Whab

  26. Multiple Introductions of Influenza A(H5N8) Virus into Poultry, Egypt, 2017

    Article • Emerging Infectious Diseases, May 2018, Centers for Disease Control and Prevention (CDC)

    Dr. El-Sayed M. Abdel-Whab

  27. Potential Biological and Climatic Factors That Influence the Incidence and Persistence of Highly Pathogenic H5N1 Avian Influenza Virus in Egypt

    Article • Frontiers in Microbiology, March 2018, Frontiers

    Dr. El-Sayed M. Abdel-Whab

  28. Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells

    Article • Viruses, February 2018, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  29. A brief summary of the epidemiology and genetic relatedness of avian influenza H9N2 virus in birds and mammals in the Middle East and North Africa

    Article • Epidemiology and Infection, November 2017, Cambridge University Press

    Dr. El-Sayed M. Abdel-Whab

  30. Pathogenicity of the Egyptian A/H5N1 avian influenza viruses in chickens

    Article • Microbial Pathogenesis, September 2017, Elsevier

    Dr. El-Sayed M. Abdel-Whab

  31. A Comprehensive Review of Common Bacterial, Parasitic and Viral Zoonoses at the Human-Animal Interface in Egypt

    Article • Pathogens, July 2017, MDPI AG

    Dr. El-Sayed M. Abdel-Whab

  32. Molecular diagnosis and characterization of Cryptosporidium spp. in turkeys and chickens in Germany reveals evidence for previously undetected parasite species

    Article • PLoS ONE, June 2017, PLOS

    Dr. El-Sayed M. Abdel-Whab

  33. Heterologous post-infection immunity against Egyptian avian influenza virus (AIV) H9N2 modulates the course of subsequent infection by highly pathogenic AIV H5N1, but vaccination immunity does not

    Article • Journal of General Virology, June 2017, Society for General Microbiology

    Dr. El-Sayed M. Abdel-Whab

  34. Isolation and genetic characterization of a novel 2.2.1.2a H5N1 virus from a vaccinated meat-turkeys flock in Egypt

    Article • Virology Journal, March 2017, Springer Science + Business Media

    Dr. El-Sayed M. Abdel-Whab

  35. Biological fitness and natural selection of amantadine resistant variants of avian influenza H5N1 viruses

    Article • Virus Research, January 2017, Elsevier

    Dr. El-Sayed M. Abdel-Whab

  36. Composition of the Hemagglutinin Polybasic Proteolytic Cleavage Motif Mediates Variable Virulence of H7N7 Avian Influenza Viruses

    Article • Scientific Reports, December 2016, Springer Science + Business Media

    Dr. El-Sayed M. Abdel-Whab

  37. Progressive glycosylation of the haemagglutinin of avian influenza H5N1 modulates virus replication, virulence and chicken-to-chicken transmission without significant impact on antigenic drift

    Article • Journal of General Virology, December 2016, Society for General Microbiology

    Dr. El-Sayed M. Abdel-Whab

  38. Introduction and enzootic of A/H5N1 in Egypt: Virus evolution, pathogenicity and vaccine efficacy ten years on

    Article • Infection Genetics and Evolution, June 2016, Elsevier

    Dr. El-Sayed M. Abdel-Whab

  39. A pallid rainbow: toward improved understanding of avian influenza biology

    Article • Future Virology, June 2016, Future Medicine

    Dr. El-Sayed M. Abdel-Whab

  40. Benefits and Limits of Egg Yolkvs. Serum Samples for Avian Influenza Virus Serosurveillance

    Article • Avian Diseases, June 2016, American Association of Avian Pathologists (AAAP)

    Dr. El-Sayed M. Abdel-Whab

  41. Evolutionary features of influenza A/H5N1 virus populations in Egypt: poultry and human health implications

    Article • Archives of Virology, April 2016, Springer Science + Business Media

    Dr. El-Sayed M. Abdel-Whab

  42. Prevalence of the C-terminal truncations of NS1 in avian influenza A viruses and effect on virulence and replication of a highly pathogenic H7N1 virus in chickens

    Article • Virulence, March 2016, Taylor & Francis

    Dr. El-Sayed M. Abdel-Whab

  43. Phylogenetic analysis of human influenza A/H3N2 viruses isolated in 2015 in Germany indicates significant genetic divergence from vaccine strains

    Article • Archives of Virology, March 2016, Springer Science + Business Media

    Dr. El-Sayed M. Abdel-Whab

  44. Different counteracting host immune responses to clade 2.2.1.1 and 2.2.1.2 Egyptian H5N1 highly pathogenic avian influenza viruses in naïve and vaccinated chickens

    Article • Veterinary Microbiology, February 2016, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  45. Improved universal cloning of influenza A virus genes by LacZα-mediated blue/white selection

    Article • Journal of Virological Methods, December 2015, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  46. Virulence of avian influenza

    Article • Journal of Virology, October 2015, ASM Journals

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  47. The Neuraminidase Stalk Deletion Serves as Major Virulence Determinant of H5N1 Highly Pathogenic Avian Influenza Viruses in Chicken

    Article • Scientific Reports, August 2015, Nature

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  48. Evolutionary trajectories and diagnostic challenges of potentially zoonotic avian influenza viruses H5N1 and H9N2 co-circulating in Egypt

    Article • Infection Genetics and Evolution, August 2015, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  49. Epidemiology and molecular characterisation of duck hepatitis A virus from different duck breeds in Egypt

    Article • Veterinary Microbiology, June 2015, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  50. Emergence of a novel cluster of influenza A(H5N1) virus clade 2.2.1.2 with putative human health impact in Egypt, 2014/15

    Article • Eurosurveillance, April 2015, European Centre for Disease Control and Prevention (ECDC)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  51. Epidemiology, ecology and gene pool of influenza A virus in Egypt: Will Egypt be the epicentre of the next influenza pandemic?

    Article • Virulence, January 2015, Taylor & Francis

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  52. In Vitro Inactivation of Two Egyptian A/H5N1 Viruses by Four Commercial Chemical Disinfectants

    Article • Avian Diseases, September 2014, American Association of Avian Pathologists (AAAP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  53. Corrigendum to ‘Protective efficacy of H5 inactivated vaccines in meat turkey poults after challenge with Egyptian variant highly pathogenic avian influenza H5N1 virus’ [Vet. Microbiol. 150 (2011) 28–34]

    Article • Veterinary Microbiology, May 2014, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  54. Prevalence and control of H7 avian influenza viruses in birds and humans – ERRATUM

    Article • Epidemiology and Infection, February 2014, Cambridge University Press

    Dr. El-Sayed M. Abdel-Whab

  55. Prevalence and control of H7 avian influenza viruses in birds and humans

    Article • Epidemiology and Infection, January 2014, Cambridge University Press

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  56. Avian influenza virus NS1

    Article • Virulence, October 2013, Taylor & Francis

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  57. Development of Real-Time Polymerase Chain Reaction Assay for Detection of Ornithobacterium rhinotracheale in Poultry

    Article • Avian Diseases, September 2013, American Association of Avian Pathologists (AAAP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  58. Genetic changes that accompanied shifts of low pathogenic avian influenza viruses toward higher pathogenicity in poultry

    Article • Virulence, August 2013, Taylor & Francis

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  59. Detection of A/H5N1 virus from asymptomatic native ducks in mid-summer in Egypt

    Article • Archives of Virology, February 2013, Springer Science + Business Media

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  60. Surveillance on A/H5N1 virus in domestic poultry and wild birds in Egypt

    Article • Virology Journal, January 2013, Springer Science + Business Media

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  61. Insight into Alternative Approaches for Control of Avian Influenza in Poultry, with Emphasis on Highly Pathogenic H5N1

    Article • Viruses, November 2012, MDPI AG

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  62. Diversifying evolution of highly pathogenic H5N1 avian influenza virus in Egypt from 2006 to 2011

    Article • Virus Genes, June 2012, Springer Science + Business Media

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  63. Isolation of H9N2 avian influenza virus from bobwhite quail (Colinus virginianus) in Egypt

    Article • Archives of Virology, March 2012, Springer Science + Business Media

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  64. Persistence of Histomonas meleagridis in or on Materials Used in Poultry Houses

    Article • Avian Diseases, March 2012, American Association of Avian Pathologists (AAAP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  65. Distribution of avian influenza H5N1 viral RNA in tissues of AI-vaccinated and unvaccinated contact chickens after experimental infection

    Article • Archives of Virology, February 2012, Springer Science + Business Media

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  66. Influence of maternal immunity on vaccine efficacy and susceptibility of one day old chicks against Egyptian highly pathogenic avian influenza H5N1

    Article • Veterinary Microbiology, February 2012, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  67. Isolation of avian influenza H5N1 virus from vaccinated commercial layer flock in Egypt

    Article • Virology Journal, January 2012, Springer Science + Business Media

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  68. Active surveillance of avian influenza virus in backyard birds in Egypt

    Article • The Journal of Applied Poultry Research, December 2011, Oxford University Press (OUP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  69. Detection and molecular characterization of Mycoplasma gallisepticum field infection in TS-11-vaccinated broiler breeders

    Article • The Journal of Applied Poultry Research, September 2011, Oxford University Press (OUP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  70. Multiple dose vaccination with heterologous H5N2 vaccine: Immune response and protection against variant clade 2.2.1 highly pathogenic avian influenza H5N1 in broiler breeder chickens

    Article • Vaccine, August 2011, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  71. Highly pathogenic avian influenza virus H5N1 from Egypt escapes vaccine-induced immunity but confers clinical protection against a heterologous clade 2.2.1 Egyptian isolate

    Article • Vaccine, July 2011, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  72. The use of FTA® filter papers for diagnosis of avian influenza virus

    Article • Journal of Virological Methods, June 2011, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  73. Protective efficacy of H5 inactivated vaccines in meat turkey poults after challenge with Egyptian variant highly pathogenic avian influenza H5N1 virus

    Article • Veterinary Microbiology, May 2011, Elsevier

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  74. An overview of the epidemic of highly pathogenic H5N1 avian influenza virus in Egypt: epidemiology and control challenges

    Article • Epidemiology and Infection, February 2011, Cambridge University Press

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  75. Modified H5 Real-Time Reverse Transcriptase–PCR Oligonucleotides for Detection of Divergent Avian Influenza H5N1 Viruses in Egypt

    Article • Avian Diseases, December 2010, American Association of Avian Pathologists (AAAP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  76. Isolation of Highly Pathogenic Avian Influenza H5N1 from Table Eggs After Vaccinal Break in Commercial Layer Flock

    Article • Avian Diseases, September 2010, American Association of Avian Pathologists (AAAP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  77. Avian influenza H5N1 virus infections in vaccinated commercial and backyard poultry in Egypt

    Article • Poultry Science, July 2010, Oxford University Press (OUP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  78. Circulation of Avian Influenza H5N1 in Live Bird Markets in Egypt

    Article • Avian Diseases, June 2010, American Association of Avian Pathologists (AAAP)

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  79. Increasing Prevalence of Unique Mutation Patterns in H5N1 Avian Influenza Virus HA and NA Glycoproteins from Human Infections in Egypt

    Article • Sequencing, January 2010, Hindawi Publishing Corporation

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  80. Simultaneous detection and differentiation by multiplex real time RT-PCR of highly pathogenic avian influenza subtype H5N1 classic (clade 2.2.1 proper) and escape mutant (clade 2.2.1 variant) lineages in Egypt

    Article • Virology Journal, January 2010, Springer Science + Business Media

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab

  81. Anatomical distribution of avian bornavirus in parrots, its occurrence in clinically healthy birds and ABV-antibody detection

    Article • Avian Pathology, November 2009, Taylor & Francis

    Dr El-Sayed M. Abdelwhab, Dr. El-Sayed M. Abdel-Whab