All Stories

  1. Ring-Strain Effects in Sommelet–Hauser Rearrangement of Five- and Six-Membered Fused Bicyclic Ammonium Ylides

    Article • Synthesis, September 2025, Thieme Publishing Group

    Dr Eiji Tayama

  2. Nitrogen- and Sulfur-Based Stevens and Related Rearrangements

    Article • January 2025, Elsevier

    Dr Eiji Tayama

  3. Controlling the position of the nucleophilic ring-opening of 2-EWG-substituted azetidinium salts with fluoride by the N-1-(1-naphthyl)ethyl substituent and BINAM-derived bis-urea organocatalyst

    Article • Tetrahedron, November 2024, Elsevier

    Dr Eiji Tayama

  4. Synthesis of α-fluoro-γ-aminobutyric acid derivatives by nucleophilic ring-opening of azetidine-2-carboxylic acid-derived ammonium salts with fluoride

    Article • Tetrahedron, August 2023, Elsevier

    Dr Eiji Tayama

  5. Recent Advances in the Generation of Onium Ylides for Sommelet–Hauser Rearrangements

    Article • Synthesis, August 2022, Thieme Publishing Group

    Dr Eiji Tayama

  6. Chiral tetraalkynylborate as a chiral solvating agent for N-chiral tetraalkylammonium salts

    Article • Tetrahedron, May 2022, Elsevier

    Dr Eiji Tayama

  7. Base-induced Sommelet–Hauser rearrangement of N-(pyridinylmethyl) tetraalkylammonium salts

    Article • Tetrahedron, April 2022, Elsevier

    Dr Eiji Tayama

  8. Synthesis of optically active 2-substituted azetidine-2-carbonitriles from chiral 1-arylethylamine via α-alkylation of N-borane complexes

    Article • RSC Advances, January 2021, Royal Society of Chemistry

    Dr Eiji Tayama

  9. Synthesis of tertiary alkyl fluorides and chlorides by site-selective nucleophilic ring-opening reaction of α-aryl azetidinium salts

    Article • RSC Advances, January 2021, Royal Society of Chemistry

    Dr Eiji Tayama

  10. Brønsted Acid-Catalyzed Aza-Ferrier Reaction of N,O-Allenyl Acetals: Synthesis of β-Amino-α-methylene Aldehydes

    Article • The Journal of Organic Chemistry, June 2020, American Chemical Society (ACS)

    Dr Eiji Tayama

  11. Base-induced Sommelet–Hauser rearrangement of N-(α-(2-oxyethyl)branched)benzylic glycine ester-derived ammonium salts via a chelated intermediate

    Article • Tetrahedron, April 2020, Elsevier

    Dr Eiji Tayama

  12. Base-promoted aromatic [3,3] sigmatropic rearrangement of N-acyl-O-arylhydroxylamine derivatives

    Article • Tetrahedron, February 2019, Elsevier

    Dr Eiji Tayama

  13. Chiral Tetraaryl- and Tetraalkynylborates as Chiral Solvating Agents for Tetraalkylammonium Salts

    Article • European Journal of Organic Chemistry, January 2019, Wiley

    Dr Eiji Tayama

  14. Dearomative [2,3] sigmatropic rearrangement of ammonium ylides

    Article • Organic & Biomolecular Chemistry, January 2018, Royal Society of Chemistry

    Dr Eiji Tayama

  15. Base-promoted diastereoselective α-alkylation of borane N-((S)-1′-phenylethyl)azetidine-2-carboxylic acid ester complexes

    Article • Organic & Biomolecular Chemistry, January 2018, Royal Society of Chemistry

    Dr Eiji Tayama

  16. Structural and mechanistic studies of the base-induced Sommelet–Hauser rearrangement of N-α-branched benzylic azetidine-2-carboxylic acid-derived ammonium salts

    Article • Organic & Biomolecular Chemistry, January 2017, Royal Society of Chemistry

    Dr Eiji Tayama

  17. Base-Induced Sommelet–Hauser Rearrangement of azetidinic acid-derived ammonium salts

    Article • European Journal of Organic Chemistry, June 2016, Wiley

    Dr Eiji Tayama

  18. Regioselective synthesis of secondary 1,3-dienamides by successive eliminations

    Article • Tetrahedron, February 2016, Elsevier

    Dr Eiji Tayama

  19. Solvent-Dependent Reaction Pathways Operating in Copper(II) Tetrafluoroborate Promoted Oxidative Ring-Opening Reactions of Cyclopropyl Silyl Ethers

    Article • The Journal of Organic Chemistry, January 2016, American Chemical Society (ACS)

    Dr Eiji Tayama

  20. Synthesis of linear [5]catenanes via olefin metathesis dimerization of pseudorotaxanes composed of a [2]catenane and a secondary ammonium salt

    Article • Chemical Communications, January 2016, Royal Society of Chemistry

    Dr Eiji Tayama

  21. Diaza [1,4] Wittig-type rearrangement of N-allylic-N-Boc-hydrazines into gamma-amino-N-Boc-enamines

    Article • Chemical Communications, January 2016, Royal Society of Chemistry

    Dr Eiji Tayama

  22. Ring-Substitution, Enlargement, and Contraction by Base-Induced Rearrangements of N-Heterocyclic Ammonium Salts

    Article • Heterocycles, January 2016, Japan Institute of Heterocyclic Chemistry

    Dr Eiji Tayama

  23. Aryl-substituted dimethylbenzimidazolines as effective reductants of photoinduced electron transfer reactions

    Article • Tetrahedron, August 2015, Elsevier

    Dr Eiji Tayama

  24. Recent Advances in the Base-Induced Sommelet-Hauser Rearrangement of Amino Acid Derived Ammonium Ylides

    Article • The Chemical Record, July 2015, Wiley

    Dr Eiji Tayama

  25. Copper-Catalyzed Regiospecific and 1,2-Regioselective Cyclopropanation of (1Z)-1-Amino- and (1Z)-1-Oxy-1,3-butadienyl Derivatives

    Article • Synlett, July 2015, Thieme Publishing Group

    Dr Eiji Tayama

  26. Metal-Free, One-Pot, Sequential Protocol for Transforming α,β-Epoxy Ketones to β-Hydroxy Ketones and α-Methylene Ketones

    Article • The Journal of Organic Chemistry, January 2015, American Chemical Society (ACS)

    Dr Eiji Tayama

  27. Stereoselective preparation of (1Z)- and (1E)-N-Boc-1-amino-1,3-dienes by stereospecific base-promoted 1,4-elimination

    Article • Tetrahedron, January 2015, Elsevier

    Dr Eiji Tayama

  28. Copper(II)–acid catalyzed cyclopropanation of 1,3-dienamides by electrophilic activation of α-aryl diazoesters

    Article • Tetrahedron Letters, May 2014, Elsevier

    Dr Eiji Tayama

  29. A photo-reagent system of benzimidazoline and Ru(bpy)3Cl2 to promote hexenyl radical cyclization and Dowd–Beckwith ring-expansion of α-halomethyl-substituted benzocyclic 1-alkanones

    Article • Tetrahedron, April 2014, Elsevier

    Dr Eiji Tayama

  30. Asymmetric [2,3] Stevens rearrangement via Memory of Chirality

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Dr Eiji Tayama

  31. New Development of Base-Induced Sommelet-Hauser Rearrangement of Ammonium Ylides

    Article • Journal of Synthetic Organic Chemistry Japan, January 2014, The Society of Synthetic Organic Chemistry, Japan

    Dr Eiji Tayama

  32. Carbon–carbon bond formation via benzoyl umpolung attained by photoinduced electron-transfer with benzimidazolines

    Article • Tetrahedron Letters, December 2013, Elsevier

    Dr Eiji Tayama

  33. Copper(II)-salt-promoted oxidative ring-opening reactions of bicyclic cyclopropanol derivatives via radical pathways

    Article • Beilstein Journal of Organic Chemistry, July 2013, Beilstein Institut

    Dr Eiji Tayama

  34. Selective Synthesis of [2]- and [3]Catenane Tuned by Ring Size and Concentration

    Article • The Journal of Organic Chemistry, May 2013, American Chemical Society (ACS)

    Dr Eiji Tayama

  35. 1,4-Elimination/Brønsted acid catalyzed aza-Ferrier reaction sequence as an entry to β-amino-β,γ-unsaturated aldehydes

    Article • Tetrahedron, April 2013, Elsevier

    Dr Eiji Tayama

  36. A Unique and Simple Preparative Method for α-Arylpipecolinic Acid Esters via Base-Induced Sommelet–Hauser Rearrangement

    Article • Heterocycles, January 2013, Japan Institute of Heterocyclic Chemistry

    Dr Eiji Tayama

  37. Copper(II)–acid co-catalyzed intermolecular substitution of electron-rich aromatics with diazoesters

    Article • Tetrahedron Letters, September 2012, Elsevier

    Dr Eiji Tayama

  38. A formal method for the de-N,N-dialkylation of Sommelet–Hauser rearrangement products

    Article • Tetrahedron, June 2012, Elsevier

    Dr Eiji Tayama

  39. 1,2-Dimethoxy-4,5-dimethylene: a new protecting group for acyclic amino acid derivatives prepared by Stevens rearrangement

    Article • Tetrahedron Letters, March 2012, Elsevier

    Dr Eiji Tayama

  40. Asymmetric α-2-tosylethenylation of N,N-dialkyl-l-amino acid estersvia the formation of non-racemic ammonium enolates

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Dr Eiji Tayama

  41. An Effective Procedure to Promote Aza–Prins Cyclization Reactions Employing a Combination of Ferric Chloride and an Imidazolium Salt in Benzotrifluoride

    Article • Heterocycles, January 2012, Japan Institute of Heterocyclic Chemistry

    Dr Eiji Tayama

  42. Asymmetric α-2-tosylvinylation of in situ-generated N-2-tosylvinyl proline-derived ammonium ylides

    Article • Tetrahedron Letters, April 2011, Elsevier

    Dr Eiji Tayama

  43. Application of biphasic reaction procedure using ferric chloride dissolved in an imidazolium salt and benzotrifluoride (FeIm-BTF procedure) to aza-Prins cyclization reaction

    Article • Tetrahedron Letters, December 2010, Elsevier

    Dr Eiji Tayama

  44. Copper(II) Triflate Catalyzed Intermolecular Aromatic Substitution of N,N-Disubstituted Anilines with Diazo Esters

    Article • European Journal of Organic Chemistry, November 2010, Wiley

    Dr Eiji Tayama

  45. Remarkable enhancement effect of potassium tert-butoxide/THF solution in base-induced Sommelet–Hauser rearrangements

    Article • Tetrahedron, November 2010, Elsevier

    Dr Eiji Tayama

  46. Resolution of nitrogen-centered chiral tetraalkylammonium salts: application to [1,2] Stevens rearrangements with N-to-C chirality transmission

    Article • Tetrahedron Asymmetry, November 2009, Elsevier

    Dr Eiji Tayama

  47. Brønsted acid catalyzed regioselective aza-Ferrier reaction: a novel synthetic method for α-(N-Boc-2-pyrrolidinyl) aldehydes

    Article • Chemical Communications, January 2008, Royal Society of Chemistry

    Dr Eiji Tayama

  48. New synthetic routes to optically active α-quaternary α-aryl amino acid derivatives via the diastereoselective Stevens and Sommelet–Hauser rearrangements

    Article • Organic & Biomolecular Chemistry, January 2008, Royal Society of Chemistry

    Dr Eiji Tayama

  49. Asymmetric Sommelet–Hauser Rearrangement of N‐Benzylic Ammonium Salts

    Article • Angewandte Chemie, November 2007, Wiley

    Dr Eiji Tayama

  50. A facile synthetic method of α-quaternary-β,γ-unsaturated aldehydes via the stereoselective 1,4-elimination and α-regioselective Ferrier reaction

    Article • Tetrahedron Letters, November 2007, Elsevier

    Dr Eiji Tayama

  51. A facile method for the stereoselective preparation of (1E,3E)-4-substituted-1-amino-1,3-dienes via 1,4-elimination

    Article • Tetrahedron Letters, August 2007, Elsevier

    Dr Eiji Tayama

  52. An efficient optical resolution of nitrogen-centered chiral β-hydroxy-tetraalkylammonium salts via complexation with (R)-BINOL

    Article • Tetrahedron Letters, June 2007, Elsevier

    Dr Eiji Tayama

  53. Regio- and Stereoselective Ferrier Reaction ofO-1,3-Dienyl Acetals Promoted by Organoaluminum Complexes

    Article • Organic Letters, November 2006, American Chemical Society (ACS)

    Dr Eiji Tayama

  54. A facile and stereoselective synthetic method for allylic 1,3-dienyl ethers

    Article • Tetrahedron Letters, October 2006, Elsevier

    Dr Eiji Tayama

  55. Asymmetric [1,2] Stevens Rearrangement of (S)-N-Benzylic Proline-derived Ammonium Salts under Biphasic Conditions

    Article • Chemistry Letters, May 2006, The Chemical Society of Japan

    Dr Eiji Tayama

  56. A Facile Method for the Stereoselective Preparation of (1Z,3E)-Dienyl Ethers via 1,4-Elimination of 1,4-Dialkoxy-(2Z)-alkenes with n-Butyllithium

    Article • Synlett, March 2006, Thieme Publishing Group

    Dr Eiji Tayama

  57. Highly Enantioselective Phase-Transfer-Catalyzed Alkylation of Protected α-Amino Acid Amides toward Practical Asymmetric Synthesis of Vicinal Diamines, α-Amino Ketones, and α-Amino Alcohols

    Article • Journal of the American Chemical Society, April 2005, American Chemical Society (ACS)

    Dr Eiji Tayama

  58. Kinetic Resolution via the [2,3] Stevens Rearrangement of Epimeric Six-membered Ammonium Ylides: A New Entry to Enantio-enriched α-Amino Acid Derivatives

    Article • Heterocycles, January 2005, Japan Institute of Heterocyclic Chemistry

    Dr Eiji Tayama

  59. Palladium-Catalyzed Intramolecular Coupling between Aryl Iodides and Allyl Moieties via Thermal and Microwave-Assisted Conditions

    Article • Journal of the American Chemical Society, January 2005, American Chemical Society (ACS)

    Dr Eiji Tayama

  60. Activation and stabilization of aldimines by an ortho-trifluoromethyl substituent in direct vinylogous Mannich-type reactions

    Article • Tetrahedron Letters, June 2004, Elsevier

    Dr Eiji Tayama

  61. Stereoselective terminal functionalization of small peptides for catalytic asymmetric synthesis of unnatural peptides

    Article • Proceedings of the National Academy of Sciences, April 2004, Proceedings of the National Academy of Sciences

    Dr Eiji Tayama

  62. (2,7-Disubstituted-1,8-biphenylenedioxy)bis(dimethylaluminum) as Bidentate Organoaluminum Lewis Acids:  Elucidation and Synthetic Utility of the Double Electrophilic Activation Phenomenon

    Article • Journal of the American Chemical Society, February 2004, American Chemical Society (ACS)

    Dr Eiji Tayama

  63. Direct Vinylogous Mannich-Type Reactions via Ring Opening and Rearrangement of Vinyloxiranes

    Article • Organic Letters, February 2004, American Chemical Society (ACS)

    Dr Eiji Tayama

  64. Practical Asymmetric Synthesis of Vicinal Diamines through the Catalytic Highly Enantioselective Alkylation of Glycine Amide Derivatives

    Article • Angewandte Chemie, December 2003, Wiley

    Dr Eiji Tayama

  65. Highly Stereoselective N-Terminal Functionalization of Small Peptides by Chiral Phase-Transfer Catalysis

    Article • Angewandte Chemie, February 2003, Wiley

    Dr Eiji Tayama

  66. Activation of ether functionality of allyl vinyl ethers by chiral bis(organoaluminum) Lewis acids: application to asymmetric Claisen rearrangement

    Article • Tetrahedron, October 2002, Elsevier

    Dr Eiji Tayama

  67. Remarkable template effect of a Lewis acid receptor in the intramolecular radical cyclization: control of reaction pathway as well as stereochemistry

    Article • Tetrahedron, January 2001, Elsevier

    Dr Eiji Tayama

  68. Dramatic Enhancement of Reactivity of Organosilicon Compounds Induced by Complexation of Bis(allyl)silanes with Fluoride Ion

    Article • Tetrahedron, July 2000, Elsevier

    Dr Eiji Tayama

  69. Efficient Synthesis of Aromatic sec-Amides from Esters: Synthetic Utility of Bislithium Amides

    Article • Synlett, June 1999, Thieme Publishing Group

    Dr Eiji Tayama

  70. Bidentate organoaluminum Lewis acid for selective activation of carbonyl over acetal functionality: Chemoselective functionalization

    Article • Tetrahedron Letters, October 1997, Elsevier

    Dr Eiji Tayama