All Stories

  1. Small-Molecule Targeting of VDAC Disrupts Mitochondrial Bioenergetics and Suppresses Melanoma Cell Survival and Migration

    Article • Cells, June 2026, MDPI AG

    Associate Professor Eduardo Nestor Maldonado

  2. Facts, Dogmas, and Unknowns About Mitochondrial Reactive Oxygen Species in Cancer

    Article • Antioxidants, December 2024, MDPI AG

    Associate Professor Eduardo Nestor Maldonado

  3. Mitochondrial Dysfunction and Metabolic Disturbances Induced by Viral Infections

    Article • Cells, October 2024, MDPI AG

    Associate Professor Eduardo Nestor Maldonado

  4. Synergism of small molecules targeting VDAC with sorafenib, regorafenib or lenvatinib on hepatocarcinoma cell proliferation and survival

    Article • European Journal of Pharmacology, October 2023, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  5. Fluorescence microscopy imaging of mitochondrial metabolism in cancer cells

    Article • Frontiers in Oncology, June 2023, Frontiers

    Associate Professor Eduardo Nestor Maldonado

  6. Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells

    Article • Biomedicine & Pharmacotherapy, June 2022, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  7. Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function

    Article • Cancer Research, April 2022, American Association for Cancer Research (AACR)

    Associate Professor Eduardo Nestor Maldonado

  8. Small molecules targeting the VDAC-NADH binding pocket modulate mitochondrial metabolism in cancer cells

    Article • Biophysical Journal, February 2022, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  9. Fast Determination of Mitochondrial Metabolism and Respiratory Complex Activity in Permeabilized and Intact Cells

    Article • January 2022, Springer Science + Business Media

    Associate Professor Eduardo Nestor Maldonado

  10. VDAC Modulation of Cancer Metabolism: Advances and Therapeutic Challenges

    Article • Frontiers in Physiology, September 2021, Frontiers

    Associate Professor Eduardo Nestor Maldonado

  11. Quantitative analysis of mitochondrial membrane potential heterogeneity in unsynchronized and synchronized cancer cells

    Article • The FASEB Journal, November 2020, Wiley

    Associate Professor Eduardo Nestor Maldonado

  12. Voltage-Dependent Anion Channels Influence Cytotoxicity of ME-344, a Therapeutic Isoflavone

    Article • Journal of Pharmacology and Experimental Therapeutics, June 2020, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Associate Professor Eduardo Nestor Maldonado

  13. Renal Glomerular Mitochondria Function in Salt-Sensitive Hypertension

    Article • Frontiers in Physiology, February 2020, Frontiers

    Associate Professor Eduardo Nestor Maldonado

  14. JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells

    Article • Biochemical Pharmacology, January 2020, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  15. Statin-dependent modulation of mitochondrial metabolism in cancer cells is independent of cholesterol content

    Article • The FASEB Journal, July 2019, Federation of American Societies For Experimental Biology (FASEB)

    Elizabeth Hunt, Associate Professor Eduardo Nestor Maldonado

  16. Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells

    Article • Biochemical Pharmacology, February 2018, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  17. VDAC Regulation: A Mitochondrial Target to Stop Cell Proliferation

    Article • January 2018, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  18. Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells

    Article • SLAS DISCOVERY, October 2017, SAGE Publications

    Associate Professor Eduardo Nestor Maldonado

  19. ATP/ADP turnover and import of glycolytic ATP into mitochondria in cancer cells is independent of the adenine nucleotide translocator.

    Article • Journal of Biological Chemistry, October 2017, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  20. VDAC1 at the crossroads of cell metabolism, apoptosis and cell stress

    Article • Cell Stress, October 2017, Shared Science Publishers OG

    Associate Professor Eduardo Nestor Maldonado

  21. VDAC–Tubulin, an Anti-Warburg Pro-Oxidant Switch

    Article • Frontiers in Oncology, January 2017, Frontiers

    Associate Professor Eduardo Nestor Maldonado

  22. ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells Is Independent of the Adenine Nucleotide Translocator

    Article • Journal of Biological Chemistry, September 2016, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  23. Oxidative Stress and JNK Activation cause Mitochondrial Dysfunction and Cell Death in Hepatocarcinoma after VDAC-Tubulin Antagonists

    Article • Biophysical Journal, February 2016, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  24. The E2F2 Transcription Factor Sustains Hepatic Glycerophospholipid Homeostasis in Mice

    Article • PLOS One, November 2014, PLOS

    Associate Professor Eduardo Nestor Maldonado

  25. ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect

    Article • Mitochondrion, November 2014, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  26. ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease

    Article • AJP Renal Physiology, September 2014, American Physiological Society

    Associate Professor Eduardo Nestor Maldonado

  27. Voltage-dependent Anion Channels Modulate Mitochondrial Metabolism in Cancer Cells

    Article • Journal of Biological Chemistry, April 2013, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  28. Mitoferrin-2-dependent Mitochondrial Iron Uptake Sensitizes Human Head and Neck Squamous Carcinoma Cells to Photodynamic Therapy

    Article • Journal of Biological Chemistry, January 2013, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  29. C-Jun N-Terminal Kinase 2 Promotes Liver Injury via the Mitochondrial Permeability Transition after Hemorrhage and Resuscitation

    Article • HPB Surgery, June 2012, Hindawi Publishing Corporation

    Associate Professor Eduardo Nestor Maldonado

  30. Warburg Revisited: Regulation of Mitochondrial Metabolism by Voltage-Dependent Anion Channels in Cancer Cells

    Article • Journal of Pharmacology and Experimental Therapeutics, June 2012, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Associate Professor Eduardo Nestor Maldonado

  31. Minocycline Decreases Liver Injury after Hemorrhagic Shock and Resuscitation in Mice

    Article • HPB Surgery, June 2012, Hindawi Publishing Corporation

    Associate Professor Eduardo Nestor Maldonado

  32. Regulation of mitochondrial function by voltage dependent anion channels in ethanol metabolism and the Warburg effect

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, June 2012, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  33. Phosphorylation of Voltage-Dependent Anion Channel by Serine/Threonine Kinases Governs Its Interaction with Tubulin

    Article • PLOS One, October 2011, PLOS

    Associate Professor Eduardo Nestor Maldonado

  34. Free Tubulin Modulates Mitochondrial Membrane Potential in Cancer Cells

    Article • Cancer Research, December 2010, American Association for Cancer Research (AACR)

    Associate Professor Eduardo Nestor Maldonado

  35. Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes

    Article • Autophagy, November 2009, Taylor & Francis

    Associate Professor Eduardo Nestor Maldonado

  36. FA2H is responsible for the formation of 2-hydroxy galactolipids in peripheral nervous system myelin

    Article • Journal of Lipid Research, January 2008, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  37. Doxorubicin Affects Testicular Lipids with Long-Chain (C18-C22) and Very Long-Chain (C24-C32) Polyunsaturated Fatty Acids

    Article • Cancer Research, July 2007, American Association for Cancer Research (AACR)

    Associate Professor Eduardo Nestor Maldonado

  38. Changes in Lipids Containing Long- and Very Long-Chain Polyunsaturated Fatty Acids in Cryptorchid Rat Testes1

    Article • Biology of Reproduction, July 2007, Oxford University Press (OUP)

    Associate Professor Eduardo Nestor Maldonado

  39. Ceramides and Sphingomyelins with High Proportions of Very Long-chain Polyunsaturated Fatty acids in Mammalian Germ Cells

    Article • Journal of Biological Chemistry, June 2007, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  40. Very Long-chain Polyunsaturated Fatty Acids Are the Major Acyl Groups of Sphingomyelins and Ceramides in the Head of Mammalian Spermatozoa

    Article • Journal of Biological Chemistry, April 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Andrés Venturino, Associate Professor Eduardo Nestor Maldonado

  41. FA2H-dependent fatty acid 2-hydroxylation in postnatal mouse brain

    Article • Journal of Lipid Research, December 2006, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  42. Differential modulation of prostaglandin receptor mRNA abundance by prostaglandins in primary cultured rat hepatocytes

    Article • Molecular and Cellular Biochemistry, November 2004, Springer Science + Business Media

    Associate Professor Eduardo Nestor Maldonado

  43. Influencia de la composición en ácidos grasos de los remanentes de quilomicrones derivados de aceite de pescado o de maíz en el perfil lipídico de los hepatocitos de rata en cultivo

    Article • Journal of Physiology and Biochemistry, June 2003, Springer Science + Business Media

    Associate Professor Eduardo Nestor Maldonado

  44. Very long chain PUFA in murine testicular triglycerides and cholesterol esters

    Article • Lipids, January 2003, Wiley

    Associate Professor Eduardo Nestor Maldonado

  45. Major plasma lipids and fatty acids in four HDL mammals

    Article • Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, June 2002, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  46. Reversibility of the changes induced by n-3 fatty acids in mouse plasma, liver and blood cell lipids

    Article • The Journal of Nutritional Biochemistry, January 2002, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  47. The influence of chylomicron remnants on cholesteryl ester metabolism in cultured rat hepatocytes: comparison of the effects of particles enriched in n-3 or n-6 polyunsaturated fatty acids

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, December 2001, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  48. Lipid and fatty acid composition of canine lipoproteins

    Article • Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, April 2001, Elsevier

    Associate Professor Eduardo Nestor Maldonado

  49. Major clofibrate effects on liver and plasma lipids are independent of changes in polyunsaturated fatty acid composition induced by dietary fat

    Article • Lipids, February 2001, Wiley

    Associate Professor Eduardo Nestor Maldonado