All Stories

  1. IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML
  2. PTCH1 is a reliable marker for predicting imatinib response in chronic myeloid leukemia patients in chronic phase
  3. Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes
  4. Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia
  5. Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognition
  6. Wilms Tumor 1 gene expression levels improve risk stratification in AML patients. Results of a multicentre study within the Spanish Group for Molecular Biology in Haematology
  7. Transcription Factor GFI1B in Health and Disease
  8. Splenectomy in ITP: we keep removing a healthy functional organ
  9. A somatic mutation of GFI1B identified in leukemia alters cell fate via a SPI1 (PU.1) centered genetic regulatory network
  10. A newNPM1gene mutation
  11. Bone marrow mesenchymal stem cells from aplastic anemia patients preserve functional and immune properties and do not contribute to the pathogenesis of the disease
  12. Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease
  13. Caracterización molecular de dos nuevas mutaciones de α° talasemia en 2 familias españolas (mutación --ED y --GP)
  14. Human promoter mutations unveil Oct-1 and GATA-1 opposite action on Gfi1b regulation
  15. GFI1B controls its own expression binding to multiple sites
  16. Haemoglobinopathies with high oxygen affinity. Experience of Erythropathology Cooperative Spanish Group
  17. Tissue-specific histone modification and transcription factor binding in   globin gene expression
  18. How transcriptional and epigenetic programmes are played out on an individual mammalian gene cluster during lineage commitment and differentiation
  19. Understanding α-Globin Gene Regulation: Aiming to Improve the Management of Thalassemia
  20. Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequences
  21. Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 loci: implications for cis-element identification
  22. Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2
  23. Deletion of the mouse alpha -globin regulatory element (HS -26) has an unexpectedly mild phenotype
  24. Identification of a conserved erythroid specific domain of histone acetylation across the α-globin gene cluster
  25. Deletion of BCR region 3′ in chronic myelogenous leukemia
  26. Monosomy for the most telomeric, gene-rich region of the short arm of human chromosome 16 causes minimal phenotypic effects
  27. THE THALASSEMIA SYNDROMES: MOLECULAR CHARACTERIZATION IN THE SPANISH POPULATION
  28. Association of t(9;11)-MLL AF9 and Trisomy 8 in an AML-M5 Preceded by Pancytopenia
  29. Acute promyelocytic leukemia relapse in the central nervous system during hematologic and molecular remission
  30. Late relapse in BCR/ABL-positive patients after non-intensive chemotherapy
  31. The first report of a Philadelphia chromosome and BCR/ABL rearrangement positive myeloproliferative disorder in a child with thrombocythemia
  32. Occurrence of BCR-ABL rearrangement in a Philadelphia chromosome-negative patient with 5q and 13q deletions and myeloproliferative syndrome
  33. Bcl-2 gene rearrangement: Diagnostic implications in a case of a large cell diffuse lymphoma appearing in leukemic phase