All Stories

  1. Translation of Inhaled Drug Optimization Strategies into Clinical Pharmacokinetics and Pharmacodynamics Using GSK2292767A, a Novel Inhaled Phosphoinositide 3-Kinase δ Inhibitor

    Article • Journal of Pharmacology and Experimental Therapeutics, April 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Edith Hessel

  2. Relationship between Pharmacokinetics and Pharmacodynamic Responses in Healthy Smokers Informs a Once-Daily Dosing Regimen for Nemiralisib

    Article • Journal of Pharmacology and Experimental Therapeutics, March 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Edith Hessel

  3. A Multicentre, Randomized, Double-Blind, Placebo-Controlled, Crossover Study To Investigate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Repeat Doses of Inhaled Nemiralisib in Adults with Persistent, Uncontrolled Asthma

    Article • Journal of Pharmacology and Experimental Therapeutics, September 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Edith Hessel

  4. First-in-Human Study With the Inhaled TLR9 Oligonucleotide Agonist AZD1419 Results in Interferon Responses in the Lung, and Is Safe and Well-Tolerated

    Article • Clinical Pharmacology & Therapeutics, December 2017, Wiley

    Edith Hessel

  5. An investigation of the anti-inflammatory effects and a potential biomarker of PI3Kδ inhibition in COPD T cells

    Article • Clinical and Experimental Pharmacology and Physiology, August 2017, Wiley

    Edith Hessel

  6. Altered fatty acid metabolism and reduced stearoyl-coenzyme a desaturase activity in asthma

    Article • Allergy, May 2017, Wiley

    Edith Hessel, Oscar Palomares

  7. Ampicillin resistance in Haemophilus influenzae from COPD patients in the UK

    Article • International Journal of Chronic Obstructive Pulmonary Disease, May 2017, Dove Medical Press

    Satyanarayana Maddi, Edith Hessel