All Stories

  1. Tumor-educated-platelets interact with breast cancer-stem-cells via P-selectin-PSGL1 and ensure stemness and metastasis through WNT-β-catenin-VEGF-VEGFR2 intra-cellular signaling: therapeutic modulation by aspirin
  2. Trogocytosis at the crossroad of cancer and immunity: mechanisms, implications and therapeutic perspectives
  3. Notch signalling in T cells: bridging tumour immunity and intratumoral cellular crosstalk
  4. Mechanistic understanding of Wiskott–Aldrich syndrome protein (WASp)-mediated epigenetic regulation of T helper cell differentiation in acute leukemia
  5. Reprogrammed immuno-metabolic environment of cancer: the driving force of ferroptosis resistance
  6. B-cell editing: An emerging alternative of precision oncotherapy
  7. Evolving Trends in Breast Cancer Immunotherapy: Recent Updates
  8. 930 Intervention on intra-tumoral breast cancer stem cells and CD8+ T cell dysregulation: the impact of 2-deoxy-D-glucose
  9. Neem Leaf Glycoprotein Disrupts Exhausted CD8+ T-Cell–Mediated Cancer Stem Cell Aggression
  10. Synthesis, structural characterization, solid-state structures, and DNA binding studies of pseudo octahedral mercury(II)-N-heterocyclic carbene (NHC) complex
  11. Neem leaf glycoprotein binding to Dectin-1 receptors on dendritic cell induces type-1 immunity through CARD9 mediated intracellular signal to NFκB
  12. The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study
  13. High monocytic MDSC signature predicts multi-drug resistance and cancer relapse in non-Hodgkin lymphoma patients treated with R-CHOP
  14. Synthesis, structures, electrochemical characterizations, theoretical and anticancer studies of Pd(II)-, Pt(II)- NHC complexes
  15. Cancer stem cell–immune cell crosstalk in breast tumor microenvironment: a determinant of therapeutic facet
  16. Terminally Exhausted CD8+ T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
  17. Tumor activated platelets induce vascular mimicry in mesenchymal stem cells and aid metastasis
  18. Lactic acid in alternative polarization and function of macrophages in tumor microenvironment
  19. NLGP regulates RGS5‐TGFβ axis to promote pericyte‐dependent vascular normalization during restricted tumor growth
  20. RGS5–TGFβ–Smad2/3 axis switches pro- to anti-apoptotic signaling in tumor-residing pericytes, assisting tumor growth
  21. Neem leaf glycoprotein salvages T cell functions from Myeloid-derived suppressor cells-suppression by altering IL-10/STAT3 axis in melanoma tumor microenvironment
  22. NLGP Attenuates Murine Melanoma and Carcinoma Metastasis by Modulating Cytotoxic CD8+ T Cells
  23. Neem Leaf Glycoprotein Restrains VEGF Production by Direct Modulation of HIF1α-Linked Upstream and Downstream Cascades
  24. Neem leaf glycoprotein regulates function of tumor associated M2 macrophages in hypoxic tumor core: Critical role of IL-10/STAT3 signaling
  25. Neem leaf glycoprotein optimizes effector and regulatory functions within tumor microenvironment to intervene therapeutically the growth of B16 melanoma in C57BL/6 mice
  26. Neem Leaf Glycoprotein Prophylaxis Transduces Immune Dependent Stop Signal for Tumor Angiogenic Switch within Tumor Microenvironment
  27. A Monoclonal Antibody Against Neem Leaf Glycoprotein Recognizes Carcinoembryonic Antigen (CEA) and Restricts CEA Expressing Tumor Growth
  28. Supraglottic laryngeal tumor microenvironmental factors facilitate STAT3 dependent pro-tumorigenic switch in tumor associated macrophages to render utmost immune evasion
  29. Neem leaf glycoprotein is superior than Cisplatin and Sunitinib malate in restricting melanoma growth by normalization of tumor microenvironment
  30. Neem leaf glycoprotein overcomes indoleamine 2,3 dioxygenase mediated tolerance in dendritic cells by attenuating hyperactive regulatory T cells in cervical cancer stage IIIB patients
  31. Tumor-Derived Vascular Pericytes Anergize Th Cells
  32. Normalization of Tumor Microenvironment by Neem Leaf Glycoprotein Potentiates Effector T Cell Functions and Therapeutically Intervenes in the Growth of Mouse Sarcoma
  33. Neem Leaf Glycoprotein Activates CD8+ T Cells to Promote Therapeutic Anti-Tumor Immunity Inhibiting the Growth of Mouse Sarcoma
  34. Neem leaf glycoprotein is nontoxic to physiological functions of Swiss mice and Sprague Dawley rats: Histological, biochemical and immunological perspectives
  35. Neem leaf glycoprotein inhibits CD4+CD25+Foxp3+Tregs to restrict murine tumor growth