All Stories

  1. B-cell editing: An emerging alternative of precision oncotherapy
  2. Neem Leaf Glycoprotein Disrupts Exhausted CD8+ T-Cell–Mediated Cancer Stem Cell Aggression
  3. Synthesis, structural characterization, solid-state structures, and DNA binding studies of pseudo octahedral mercury(II)-N-heterocyclic carbene (NHC) complex
  4. Neem leaf glycoprotein binding to Dectin-1 receptors on dendritic cell induces type-1 immunity through CARD9 mediated intracellular signal to NFκB
  5. The immunomodulatory impact of naturally derived neem leaf glycoprotein on the initiation progression model of 4NQO induced murine oral carcinogenesis: a preclinical study
  6. High monocytic MDSC signature predicts multi-drug resistance and cancer relapse in non-Hodgkin lymphoma patients treated with R-CHOP
  7. Synthesis, structures, electrochemical characterizations, theoretical and anticancer studies of Pd(II)-, Pt(II)- NHC complexes
  8. Cancer stem cell–immune cell crosstalk in breast tumor microenvironment: a determinant of therapeutic facet
  9. Terminally Exhausted CD8+ T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
  10. Tumor activated platelets induce vascular mimicry in mesenchymal stem cells and aid metastasis
  11. Lactic acid in alternative polarization and function of macrophages in tumor microenvironment
  12. NLGP regulates RGS5‐TGFβ axis to promote pericyte‐dependent vascular normalization during restricted tumor growth
  13. RGS5–TGFβ–Smad2/3 axis switches pro- to anti-apoptotic signaling in tumor-residing pericytes, assisting tumor growth
  14. Neem leaf glycoprotein salvages T cell functions from Myeloid-derived suppressor cells-suppression by altering IL-10/STAT3 axis in melanoma tumor microenvironment
  15. NLGP Attenuates Murine Melanoma and Carcinoma Metastasis by Modulating Cytotoxic CD8+ T Cells
  16. Neem Leaf Glycoprotein Restrains VEGF Production by Direct Modulation of HIF1α-Linked Upstream and Downstream Cascades
  17. Neem leaf glycoprotein regulates function of tumor associated M2 macrophages in hypoxic tumor core: Critical role of IL-10/STAT3 signaling
  18. Neem leaf glycoprotein optimizes effector and regulatory functions within tumor microenvironment to intervene therapeutically the growth of B16 melanoma in C57BL/6 mice
  19. Neem Leaf Glycoprotein Prophylaxis Transduces Immune Dependent Stop Signal for Tumor Angiogenic Switch within Tumor Microenvironment
  20. A Monoclonal Antibody Against Neem Leaf Glycoprotein Recognizes Carcinoembryonic Antigen (CEA) and Restricts CEA Expressing Tumor Growth
  21. Supraglottic laryngeal tumor microenvironmental factors facilitate STAT3 dependent pro-tumorigenic switch in tumor associated macrophages to render utmost immune evasion
  22. Neem leaf glycoprotein is superior than Cisplatin and Sunitinib malate in restricting melanoma growth by normalization of tumor microenvironment
  23. Neem leaf glycoprotein overcomes indoleamine 2,3 dioxygenase mediated tolerance in dendritic cells by attenuating hyperactive regulatory T cells in cervical cancer stage IIIB patients
  24. Tumor-Derived Vascular Pericytes Anergize Th Cells
  25. Normalization of Tumor Microenvironment by Neem Leaf Glycoprotein Potentiates Effector T Cell Functions and Therapeutically Intervenes in the Growth of Mouse Sarcoma
  26. Neem Leaf Glycoprotein Activates CD8+ T Cells to Promote Therapeutic Anti-Tumor Immunity Inhibiting the Growth of Mouse Sarcoma
  27. Neem leaf glycoprotein is nontoxic to physiological functions of Swiss mice and Sprague Dawley rats: Histological, biochemical and immunological perspectives
  28. Neem leaf glycoprotein inhibits CD4+CD25+Foxp3+Tregs to restrict murine tumor growth