All Stories

  1. Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far

    Article • Biotechnology and Bioengineering, July 2025, Wiley

    Dr. Emmanuel T Osei

  2. Establishing a 3D Vascularized Tri‐Culture Model of the Human Airways via a Digital Light Processing Bioprinter

    Article • Biotechnology and Bioengineering, April 2025, Wiley

    Dr. Emmanuel T Osei

  3. Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair

    Article • Matrix Biology, September 2024, Elsevier

    Dr. Emmanuel T Osei

  4. The effect of the mechanodynamic lung environment on fibroblast phenotype via the Flexcell

    Article • BMC Pulmonary Medicine, July 2024, Springer Science + Business Media

    Dr. Emmanuel T Osei

  5. Editorial: Next generation in vitro models to study chronic pulmonary diseases

    Article • Frontiers in Medicine, December 2023, Frontiers

    Dr. Emmanuel T Osei

  6. In vitro co-culture studies and the crucial role of fibroblast-immune cell crosstalk in IPF pathogenesis

    Article • November 2023, Springer Science + Business Media

    Dr. Emmanuel T Osei

  7. Epithelial-fibroblast interactions in IPF: Lessons from in vitro co-culture studies

    Article • Differentiation, November 2023, Elsevier

    Dr. Emmanuel T Osei

  8. 3D in vitro hydrogel models to study the human lung extracellular matrix and fibroblast function

    Article • October 2023, Springer Science + Business Media

    Dr. Emmanuel T Osei

  9. The contribution of reticular basement membrane proteins to basal airway epithelial attachment, spreading and barrier formation: implications for airway remodeling in asthma

    Article • Frontiers in Medicine, September 2023, Frontiers

    Dr. Emmanuel T Osei

  10. Understanding fibroblast-immune cell interactions via co-culture models and their role in asthma pathogenesis

    Article • Frontiers in Immunology, February 2023, Frontiers

    Dr. Emmanuel T Osei

  11. Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma

    Article • Cells, September 2022, MDPI AG

    Dr. Emmanuel T Osei

  12. The Role of the Dynamic Lung Extracellular Matrix Environment on Fibroblast Morphology and Inflammation

    Article • Cells, January 2022, MDPI AG

    Dr. Emmanuel T Osei

  13. Modeling Extracellular Matrix-Cell Interactions in Lung Repair and Chronic Disease

    Article • Cells, August 2021, MDPI AG

    Dr. Emmanuel T Osei

  14. Canadian lung tissue biobank with associated clinical data supporting respiratory research for four decades

    Article • Canadian Journal of Respiratory Critical Care and Sleep Medicine, March 2021, Taylor & Francis

    Dr. Emmanuel T Osei

  15. Second harmonic generation imaging of collagen scaffolds within the alveolar ducts of healthy and emphysematous mouse lungs

    Article • Histochemistry and Cell Biology, January 2021, Springer Science + Business Media

    Dr. Emmanuel T Osei

  16. Epithelial-mesenchymal crosstalk in COPD: An update from in vitro model studies

    Article • The International Journal of Biochemistry & Cell Biology, August 2020, Elsevier

    Dr. Emmanuel T Osei

  17. What Have In Vitro Co-Culture Models Taught Us about the Contribution of Epithelial-Mesenchymal Interactions to Airway Inflammation and Remodeling in Asthma?

    Article • Cells, July 2020, MDPI AG

    Dr. Emmanuel T Osei

  18. Epithelial-interleukin-1 inhibits collagen formation by airway fibroblasts: Implications for asthma

    Article • Scientific Reports, May 2020, Springer Science + Business Media

    Dr. Emmanuel T Osei

  19. Super resolution measurement of collagen fibers in biological samples: Validation of a commercial solution for multiphoton microscopy

    Article • PLOS One, February 2020, PLOS

    Dr. Emmanuel T Osei

  20. Current perspectives on the role of interleukin-1 signalling in the pathogenesis of asthma and COPD

    Article • European Respiratory Journal, November 2019, European Respiratory Society (ERS)

    Dr. Emmanuel T Osei

  21. Defective Fibrillar Collagen Organization by Fibroblasts Contributes to Airway Remodeling in Asthma

    Article • American Review of Respiratory Disease, August 2019, American Thoracic Society

    Dr. Emmanuel T Osei

  22. miR-146a-5p plays an essential role in the aberrant epithelial–fibroblast cross-talk in COPD

    Article • European Respiratory Journal, May 2017, European Respiratory Society (ERS)

    Dr. Emmanuel T Osei

  23. Interleukin-1α drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD

    Article • European Respiratory Journal, July 2016, European Respiratory Society (ERS)

    Dr. Emmanuel T Osei

  24. Unravelling the complexity of COPD by microRNAs: it's a small world after all

    Article • European Respiratory Journal, August 2015, European Respiratory Society (ERS)

    Dr. Emmanuel T Osei