All Stories

  1. HOIL1 mediates MDA5 activation through ubiquitination of LGP2

    Article • April 2024, openRxiv

    Dr Donna A MacDuff

  2. HOIL1 Regulates Group 3 Innate Lymphoid Cells in the Colon and Protects against Systemic Dissemination, Colonic Ulceration, and Lethality from Citrobacter rodentium Infection

    Article • The Journal of Immunology, October 2023, Oxford University Press (OUP)

    Dr Donna A MacDuff

  3. HOIL1 regulates group 3 innate lymphoid cell numbers in the colon and protects against systemic dissemination, colonic ulceration, and lethality from Citrobacter rodentium infection

    Article • May 2023, openRxiv

    Dr Donna A MacDuff

  4. HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine

    Article • Mucosal Immunology, April 2022, Elsevier

    Dr Donna A MacDuff

  5. HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine

    Article • March 2022, openRxiv

    Dr Donna A MacDuff

  6. An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread

    Article • Nature Microbiology, November 2018, Springer Science + Business Media

    Dr Donna A MacDuff

  7. HOIL1 Is Essential for the Induction of Type I and III Interferons by MDA5 and Regulates Persistent Murine Norovirus Infection

    Article • Journal of Virology, September 2018, ASM Journals

    Dr Donna A MacDuff

  8. Tropism for tuft cells determines immune promotion of norovirus pathogenesis

    Article • Science, April 2018, American Association for the Advancement of Science

    Dr Donna A MacDuff

  9. Erratum: Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

    Article • Nature, July 2015, Springer Science + Business Media

    Dr Donna A MacDuff

  10. The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

    Article • Cell Host & Microbe, June 2015, Elsevier

    Dr Donna A MacDuff

  11. Mitochondrial DNA stress primes the antiviral innate immune response

    Article • Nature, February 2015, Springer Science + Business Media

    Dr Donna A MacDuff

  12. Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection

    Article • eLife, January 2015, eLife

    Dr Donna A MacDuff

  13. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

    Article • Nature, November 2013, Springer Science + Business Media

    Professor Eric J. Snijder, Dr Donna A MacDuff

  14. Identification of a candidate therapeutic autophagy-inducing peptide

    Article • Nature, January 2013, Springer Science + Business Media

    Dr Donna A MacDuff

  15. APOBEC3 inhibits DEAD-END function to regulate microRNA activity

    Article • BMC Molecular Biology, January 2013, Springer Science + Business Media

    Dr Donna A MacDuff

  16. Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

    Article • Nature Immunology, October 2012, Springer Science + Business Media

    Dr Donna A MacDuff, Professor Damien Bonnet

  17. The Interaction between AID and CIB1 Is Nonessential for Antibody Gene Diversification by Gene Conversion or Class Switch Recombination

    Article • PLOS One, July 2010, PLOS

    Dr Donna A MacDuff

  18. AID can restrict L1 retrotransposition suggesting a dual role in innate and adaptive immunity

    Article • Nucleic Acids Research, February 2009, Oxford University Press (OUP)

    Dr Donna A MacDuff

  19. The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction

    Article • Journal of Virology, January 2008, ASM Journals

    Dr Donna A MacDuff

  20. Directed DNA deamination by AID/APOBEC3 in immunity

    Article • Current Biology, March 2006, Elsevier

    Dr Donna A MacDuff

  21. MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells

    Article • Molecular Immunology, March 2006, Elsevier

    Dr Donna A MacDuff

  22. Antibody Gene Diversification by Aid-Catalyzed DNA Editing

    Article • Wiley

    Dr Donna A MacDuff