All Stories

  1. TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding

    Article • PLoS Biology, March 2023, PLOS

    Don Ayer

  2. Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation

    Article • Molecular and Cellular Biology, July 2018, ASM Journals

    Don Ayer

  3. Abstract A49: MondoA-TXNIP acts as a metabolic checkpoint for coordinated cell growth

    Article • Molecular Cancer Research, January 2016, American Association for Cancer Research (AACR)

    Don Ayer

  4. Interactions between Myc and MondoA transcription factors in metabolism and tumourigenesis

    Article • British Journal of Cancer, October 2015, Springer Science + Business Media

    Don Ayer

  5. MONDOA Is Required for MYC-Driven Metabolic Changes

    Article • Cancer Discovery, February 2015, American Association for Cancer Research (AACR)

    Don Ayer

  6. MondoA-Mlx Transcriptional Activity Is Limited by mTOR-MondoA Interaction

    Article • Molecular and Cellular Biology, October 2014, ASM Journals

    Don Ayer

  7. Response to Acidity: The MondoA–TXNIP Checkpoint Couples the Acidic Tumor Microenvironment to Cell Metabolism

    Article • January 2014, Springer Science + Business Media

    Don Ayer

  8. MondoA senses adenine nucleotides: transcriptional induction of thioredoxin-interacting protein

    Article • Biochemical Journal, July 2013, Portland Press Ltd.

    Don Ayer

  9. MondoA Senses Non-glucose Sugars: REGULATION OF THIOREDOXIN-INTERACTING PROTEIN (TXNIP) AND THE HEXOSE TRANSPORT CURB

    Article • Journal of Biological Chemistry, September 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Don Ayer

  10. Lactic Acidosis Triggers Starvation Response with Paradoxical Induction of TXNIP through MondoA

    Article • PLoS Genetics, September 2010, PLOS

    Don Ayer

  11. Glucose Controls Nuclear Accumulation, Promoter Binding, and Transcriptional Activity of the MondoA-Mlx Heterodimer

    Article • Molecular and Cellular Biology, April 2010, ASM Journals

    Don Ayer

  12. Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity

    Article • Proceedings of the National Academy of Sciences, September 2009, Proceedings of the National Academy of Sciences

    Don Ayer

  13. MondoA-Mlx Heterodimers Are Candidate Sensors of Cellular Energy Status: Mitochondrial Localization and Direct Regulation of Glycolysis

    Article • Molecular and Cellular Biology, July 2006, ASM Journals

    Don Ayer

  14. A Novel Heterodimerization Domain, CRM1, and 14-3-3 Control Subcellular Localization of the MondoA-Mlx Heterocomplex

    Article • Molecular and Cellular Biology, December 2002, ASM Journals

    Don Ayer

  15. MondoA, a Novel Basic Helix-Loop-Helix–Leucine Zipper Transcriptional Activator That Constitutes a Positive Branch of a Max-Like Network

    Article • Molecular and Cellular Biology, December 2000, ASM Journals

    Don Ayer