All Stories

  1. AMPK-FOXO-IP3R signaling pathway mediates defects caused by mitochondrial DNA mutations

    Article • Proceedings of the National Academy of Sciences, August 2023, Proceedings of the National Academy of Sciences

    Professor Ding Xue

  2. Acoustic streaming enabled moderate swimming exercise reduces neurodegeneration in C. elegans

    Article • Science Advances, February 2023, American Association for the Advancement of Science

    Professor Ding Xue

  3. Programmed Cell Death DuringCaenorhabditis elegansDevelopment

    Article • Genetics, August 2016, Oxford University Press (OUP)

    Professor Ding Xue

  4. Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

    Article • Science, July 2016, American Association for the Advancement of Science

    Professor Ding Xue

  5. CED-3 caspase acts with miRNAs to regulate non-apoptotic gene expression dynamics for robust development in C. elegans

    Article • eLife, December 2014, eLife

    Professor Min Han, Professor Ding Xue

  6. Oligonucleotide-based targeted gene editing in C. elegans via the CRISPR/Cas9 system

    Article • Cell Research, January 2014, Springer Science + Business Media

    Professor Ding Xue

  7. A novel mechanism underlies caspase-dependent conversion of the dicer ribonuclease into a deoxyribonuclease during apoptosis

    Article • Cell Research, December 2013, Springer Science + Business Media

    Professor Ding Xue

  8. Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalization

    Article • Nature Communications, November 2013, Springer Science + Business Media

    Professor Ding Xue

  9. MARCKS-ED Peptide as a Curvature and Lipid Sensor

    Article • ACS Chemical Biology, October 2012, American Chemical Society (ACS)

    Professor Ding Xue

  10. Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca 2+ increase and cell death in Caenorhabditis elegans

    Article • Proceedings of the National Academy of Sciences, September 2012, Proceedings of the National Academy of Sciences

    Professor Ding Xue

  11. Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction

    Article • Proceedings of the National Academy of Sciences, September 2012, Proceedings of the National Academy of Sciences

    Professor Ding Xue

  12. CED-1, CED-7, and TTR-52 Regulate Surface Phosphatidylserine Expression on Apoptotic and Phagocytic Cells

    Article • Current Biology, July 2012, Elsevier

    Professor Ding Xue

  13. Structural Insights into Apoptotic DNA Degradation by CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans

    Article • Journal of Biological Chemistry, March 2012, Elsevier

    Professor Ding Xue

  14. Methods for Studying Programmed Cell Death in C. elegans

    Article • January 2012, Elsevier

    Professor Ding Xue

  15. Elimination of paternal mitochondria through the lysosomal degradation pathway in C. elegans

    Article • Cell Research, November 2011, Springer Science + Business Media

    Professor Ding Xue

  16. Dicing up chromosomes: The unexpected role of Dicer in apoptosis 

    Article • Cell Cycle, December 2010, Taylor & Francis

    Professor Ding Xue

  17. Somatic sex determination in Caenorhabditis elegans is modulated by SUP-26 repression of tra-2 translation

    Article • Proceedings of the National Academy of Sciences, October 2010, Proceedings of the National Academy of Sciences

    Professor Ding Xue

  18. Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor

    Article • Nature Cell Biology, June 2010, Springer Science + Business Media

    Professor Ding Xue

  19. Programmed cell clearance: Molecular regulation of the elimination of apoptotic cell corpses and its role in the resolution of inflammation

    Article • Biochemical and Biophysical Research Communications, May 2010, Elsevier

    Professor Ding Xue

  20. Caspase-Dependent Conversion of Dicer Ribonuclease into a Death-Promoting Deoxyribonuclease

    Article • Science, April 2010, American Association for the Advancement of Science

    Professor Ding Xue

  21. The Roles and Acting Mechanism of Caenorhabditis elegans DNase II Genes in Apoptotic DNA Degradation and Development

    Article • PLoS ONE, October 2009, PLOS

    Professor Ding Xue

  22. The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease

    Article • Critical Reviews in Biochemistry and Molecular Biology, September 2009, Taylor & Francis

    Professor Ding Xue

  23. Caenorhabditis elegans caspase homolog CSP-2 inhibits CED-3 autoactivation and apoptosis in germ cells

    Article • Cell Death and Differentiation, July 2009, Springer Science + Business Media

    Professor Ding Xue

  24. Bcl-2 Proteins EGL-1 and CED-9 Do Not Regulate Mitochondrial Fission or Fusion in Caenorhabditis elegans

    Article • Current Biology, May 2009, Elsevier

    Professor Ding Xue

  25. Programmed Cell Death in C. elegans

    Article • January 2009, Springer Science + Business Media

    Professor Ding Xue

  26. Crystal Structure of CRN-4: Implications for Domain Function in Apoptotic DNA Degradation

    Article • Molecular and Cellular Biology, November 2008, ASM Journals

    Professor Ding Xue

  27. SKR-1, a homolog of Skp1 and a member of the SCFSEL-10 complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans

    Article • Developmental Biology, October 2008, Elsevier

    Professor Ding Xue

  28. Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3

    Article • Nature Structural & Molecular Biology, September 2008, Springer Science + Business Media

    Professor Ding Xue

  29. Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent of ced-9

    Article • Molecular Cell, August 2008, Elsevier

    Professor Ding Xue

  30. Role ofC. elegansTAT-1 Protein in Maintaining Plasma Membrane Phosphatidylserine Asymmetry

    Article • Science, April 2008, American Association for the Advancement of Science

    Professor Ding Xue

  31. Control of sex-specific apoptosis in C. elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho

    Article • Genes & Development, December 2007, Cold Spring Harbor Laboratory Press

    Professor Ding Xue

  32. C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1

    Article • Nature Cell Biology, April 2007, Springer Science + Business Media

    Professor Ding Xue

  33. A Class of Benzenoid Chemicals Suppresses Apoptosis in C. elegans

    Article • ChemBioChem, November 2006, Wiley

    Professor Ding Xue

  34. The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans

    Article • Nature Chemical Biology, May 2006, Springer Science + Business Media

    Professor Ding Xue

  35. RNA Aptamers Targeting the Cell Death Inhibitor CED-9 Induce Cell Killing in Caenorhabditis elegans

    Article • Journal of Biological Chemistry, April 2006, Elsevier

    Professor Ding Xue

  36. Cuts can kill: the roles of apoptotic nucleases in cell death and animal development

    Article • Chromosoma, January 2006, Springer Science + Business Media

    Professor Ding Xue

  37. PS externalization: from corpse clearance to drug delivery

    Article • Cell Death and Differentiation, December 2005, Springer Science + Business Media

    Professor Ding Xue

  38. Structure of the CED-4–CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans

    Article • Nature, October 2005, Springer Science + Business Media

    Professor Ding Xue

  39. Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks

    Article • EMBO Reports, January 2005, EMBO

    Professor Ding Xue

  40. Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases

    Article • Current Opinion in Cell Biology, December 2004, Elsevier

    Professor Ding Xue

  41. Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4

    Article • Molecular Cell, September 2004, Elsevier

    Professor Ding Xue

  42. To Live or Die by the Sword

    Article • Developmental Cell, April 2004, Elsevier

    Professor Ding Xue

  43. Cell Corpse Engulfment Mediated byC. elegansPhosphatidylserine Receptor Through CED-5 and CED-12

    Article • Science, November 2003, American Association for the Advancement of Science

    Professor Ding Xue

  44. CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation

    Article • The EMBO Journal, July 2003, Wiley

    Professor Ding Xue

  45. Functional Genomic Analysis of Apoptotic DNA Degradation in C. elegans

    Article • Molecular Cell, April 2003, Elsevier

    Professor Ding Xue

  46. Mechanisms of AIF-Mediated Apoptotic DNA Degradation in Caenorhabditis elegans

    Article • Science, November 2002, American Association for the Advancement of Science

    Professor Ding Xue

  47. Mitochondrial endonuclease G is important for apoptosis in C. elegans

    Article • Nature, July 2001, Springer Science + Business Media

    Professor Ding Xue

  48. If phosphatidylserine is the death knell, a new phosphatidylserine-specific receptor is the bellringer

    Article • Cell Death and Differentiation, June 2001, Springer Science + Business Media

    Professor Ding Xue

  49. Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors

    Article • Proceedings of the National Academy of Sciences, October 2000, Proceedings of the National Academy of Sciences

    Professor Ding Xue

  50. Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor

    Article • Nature, November 1997, Springer Science + Business Media

    Professor Ding Xue

  51. Phosphorylation of IκB-α Inhibits Its Cleavage by Caspase CPP32 in Vitro

    Article • Journal of Biological Chemistry, November 1997, Elsevier

    Professor Ding Xue