All Stories

  1. Self-oxidation and proximity crosslinking of G-quadruplex in G-quadruplex /hemin peroxidase system
  2. Detection and Verification of Intestinal and Placental Alkaline Phosphatase Heterodimer in Extracellular Fluid
  3. DNA aptamer targeting zinc transporters ZIP10 and ZIP6 on cancer cells
  4. Embedding Dual-Responsive Polymer@Enzyme in Zeolitic Imidazolate Frameworks with a Hollow Space for Improving Its Catalytic Performance
  5. A preliminary profile of RNA bound on the cell surface
  6. A Comparative Study on the DNA Interactions and Biological Activities of Benzophenanthridine and Protoberberine Alkaloids
  7. A Bispecific Chimeric Aptamer Design Platform Based on c‐MET Aptamer with a Replaceable Redundant Region
  8. A naphthalimide-based fluorescent platform for endoplasmic reticulum targeted imaging
  9. Heptamethine Cyanine-Based Molecule Release Triggered by Mitochondrial ROS
  10. DNA Aptamer Binding Octapeptide Repeat Region of Cellular Prion Protein
  11. Structural Optimization and Interaction Study of a DNA Aptamer to L1 Cell Adhesion Molecule
  12. Generation of an Aptamer Targeting Receptor-Type Tyrosine-Protein Phosphatase F
  13. Potential G‐quadruplexes within the Promoter Nuclease Hypersensitive Sites of the Heat‐Responsive Genes in Rice
  14. Characterization and Identification of Aptamers against CD49c for the Detection, Capture, and Release of Cancer Cells
  15. Aptamer-Based Cell Nucleus Imaging via Expansion Microscopy
  16. Transferrin receptor-mediated internalization and intracellular fate of conjugates of a DNA aptamer
  17. A photo-activated aptamer–drug conjugate for targeted drug delivery
  18. Cell-SELEX-based selection of ssDNA aptamers for specifically targeting BRAF V600E-mutated melanoma
  19. A DNA Aptameric Ligand of Human Transferrin Receptor Generated by Cell-SELEX
  20. A 4-aminonaphthalimide-based fluorescent traceable prodrug with excellent photoinduced cytotoxicity
  21. Detection of Circulating Tumor-Related Materials by Aptamer Capturing and Endogenous Enzyme-Signal Amplification
  22. Prion Protein Targeted by a Prostate Cancer Cell Binding Aptamer, a Potential Tumor Marker?
  23. Thiazole Orange Styryl Derivatives as Fluorescent Probes for G-Quadruplex DNA
  24. FnCas12a/crRNA assisted dumbbell-PCR detection of IsomiRs with terminal and inner sequence variants
  25. Ratiometric detection and imaging of hydrogen sulfide in mitochondria based on a cyanine/naphthalimide hybrid fluorescent probe
  26. Cell‐SELEX, an Effective Way to the Discovery of Biomarkers and Unexpected Molecular Events
  27. Speeding up in Vitro Discovery of Structure-Switching Aptamers via Magnetic Cross-Linking Precipitation
  28. Dual-Monitoring Glycosylation and Local pH in Live Cells by Metabolic Oligosaccharide Engineering with a Ratiometric Fluorescent Tag
  29. A Nucleus-Targeting DNA Aptamer for Dead Cell Indication
  30. The Mechanism of the Selective Antiproliferation Effect of Guanine-Based Biomolecules and Its Compensation
  31. Aptameric Probe Specifically Binding Protein Heterodimer Rather Than Monomers
  32. In vitro selection of DNA aptamers recognizing drug-resistant ovarian cancer by cell-SELEX
  33. A Mitochondria-Targeted Ratiometric Fluorescent pH Probe
  34. Imaging of Neurite Network with an Anti-L1CAM Aptamer Generated by Neurite-SELEX
  35. Simultaneous Monitoring of Mitochondrial Temperature and ATP Fluctuation Using Fluorescent Probes in Living Cells
  36. Thiazole Orange-Modified Carbon Dots for Ratiometric Fluorescence Detection of G-Quadruplex and Double-Stranded DNA
  37. Oxidative degradation of polyamines by serum supplement causes cytotoxicity on cultured cells
  38. Flow Cytometric Bead Sandwich Assay Based on a Split Aptamer
  39. Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in Vivo
  40. Triplex-quadruplex structural scaffold: a new binding structure of aptamer
  41. Quinacridone derivative as a new photosensitizer: Photodynamic effects in cells and in vivo
  42. Dicyanomethylene Substituted Benzothiazole Squaraines: The Efficiency of Photodynamic Therapy In Vitro and In Vivo
  43. Detection of G-Quadruplex Structures Formed by G-Rich Sequences from Rice Genome and Transcriptome Using Combined Probes
  44. Development of squaraine based G-quadruplex ligands using click chemistry
  45. Microbead-Based Platform for Multiplex Detection of DNA and Protein
  46. Multifunctional hard-shelled microbubbles for differentiating imaging, cavitation and drug release by ultrasound
  47. Ratiometric Fluorescent Biosensing of Hydrogen Peroxide and Hydroxyl Radical in Living Cells with Lysozyme–Silver Nanoclusters: Lysozyme as Stabilizing Ligand and Fluorescence Signal Unit
  48. A Protease-Activated Ratiometric Fluorescent Probe for pH-Mapping of Malignant Tumor
  49. A Cyanine Dye to Probe Mitophagy: Simultaneous Detection of Mitochondria and Autolysosomes in Live Cells
  50. Interaction of hypericin with guanine-rich DNA: Preferential binding to parallel G-Quadruplexes
  51. A Bis(methylpiperazinylstyryl)phenanthroline as a Fluorescent Ligand for G-Quadruplexes
  52. Intercellular Connections Related to Cell-Cell Crosstalk Specifically Recognized by an Aptamer
  53. Intercellular Connections Related to Cell-Cell Crosstalk Specifically Recognized by an Aptamer
  54. Activity Enhancement of G-Quadruplex/Hemin DNAzyme by Flanking d(CCC)
  55. Generating Cell Targeting Aptamers for Nanotheranostics Using Cell-SELEX
  56. DNA interaction, cellular localization and cytotoxicity of quinacridone derivatives
  57. Facile Phase Transfer and Surface Biofunctionalization of Hydrophobic Nanoparticles Using Janus DNA Tetrahedron Nanostructures
  58. Facile Discovery of Cell-Surface Protein Targets of Cancer Cell Aptamers
  59. Protease-Activated Ratiometric Fluorescent Probe for pH Mapping of Malignant Tumors
  60. Ultra-high-performance liquid chromatography electrospray ionization tandem mass spectrometry for accurate analysis of glycerophospholipids and sphingolipids in drug resistance tumor cells
  61. Visible-light-induced cleavage of 4-α-amino acid substituted naphthalimides and its application in DNA photocleavage
  62. Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides
  63. Cell-SELEX: Aptamer Selection Against Whole Cells
  64. Ratiometric fluorescent silver nanoclusters for the determination of mercury and copper ions
  65. Interaction of bisbenzimidazole-substituted carbazole derivatives with G-quadruplexes and living cells
  66. Cell-SELEX-based selection of aptamers that recognize distinct targets on metastatic colorectal cancer cells
  67. Dicyanomethylene-Functionalized Squaraine as a Highly Selective Probe for Parallel G-Quadruplexes
  68. DNA Aptamer Evolved by Cell-SELEX for Recognition of Prostate Cancer
  69. Carbon Dots Based Dual-Emission Silica Nanoparticles as a Ratiometric Nanosensor for Cu 2+
  70. Mass Spectrometric Proteomics Reveals that Nuclear Protein Positive Cofactor PC4 Selectively Binds to Cross-Linked DNA by a trans -Platinum Anticancer Complex
  71. Fluorescence Light-Up Probe for Parallel G-Quadruplexes
  72. Activity enhancement of G-quadruplex/hemin DNAzyme by spermine
  73. Exact tailoring of an ATP controlled streptavidin binding aptamer
  74. Effects of side chains on DNA binding, cell permeability, nuclear localization and cytotoxicity of 4-aminonaphthalimides
  75. A label-free electrochemical biosensor based on a DNA aptamer against codeine
  76. One-step real time RT-PCR for detection of microRNAs
  77. General Cell-Binding Activity of Intramolecular G-Quadruplexes with Parallel Structure
  78. G-quadruplex DNA aptamers for zeatin recognizing
  79. A turn-on fluorescent sensor for zinc and cadmium ions based on perylene tetracarboxylic diimide
  80. Rational design of Hg2+controlled streptavidin-binding aptamer
  81. A guanidine derivative of naphthalimide with excited-state deprotonation coupled intramolecular charge transfer properties and its application
  82. A pH sensitive ratiometric fluorophore and its application for monitoring the intracellular and extracellular pHs simultaneously
  83. Specific interactions between adenosine and streptavidin/avidin
  84. Functional-Group Specific Aptamers Indirectly Recognizing Compounds with Alkyl Amino Group
  85. Selective isolation of G-quadruplexes by affinity chromatography
  86. PEG-urokinase nanogels with enhanced stability and controllable bioactivity
  87. Thermal responsive fluorescent block copolymer for intracellular temperature sensing
  88. Characterization of G-Quadruplex/Hemin Peroxidase: Substrate Specificity and Inactivation Kinetics
  89. G-quadruplex DNA aptamers generated for systemin
  90. Characterization and application of a DNA aptamer binding to l-tryptophan
  91. Mercury(ii)-mediated formation of imide-Hg-imide complexes
  92. Silencing of PTK7 in Colon Cancer Cells: Caspase-10-Dependent Apoptosis via Mitochondrial Pathway
  93. Development of DNA aptamers using Cell-SELEX
  94. Cancer Cell Proteomics using Molecular Aptamers
  95. Conservative secondary structure motif of streptavidin-binding aptamers generated by different laboratories
  96. Bifunctional combined aptamer for simultaneous separation and detection of thrombin
  97. Visual Detection of Hg2+ with High Selectivity Using Thymine Modified Gold Nanoparticles
  98. Specific DNA G-quadruplexes bind to ethanolamines
  99. General Peroxidase Activity of G-Quadruplex−Hemin Complexes and Its Application in Ligand Screening
  100. Highly Selective Phthalocyanine−Thymine Conjugate Sensor for Hg 2+ Based on Target Induced Aggregation
  101. Specific mercury(II) adsorption by thymine-based sorbent
  102. Molecular Assembly of an Aptamer-Drug Conjugate for Targeted Drug Delivery to Tumor Cells
  103. A label-free fluorescence sensor for probing the interaction of oligonucleotides with target molecules
  104. Molecular recognition of acute myeloid leukemia using aptamers
  105. Recognition of subtype non-small cell lung cancer by DNA aptamers selected from living cells
  106. Fluorescent Aptamer Sensors
  107. Molecular Recognition of Small-Cell Lung Cancer Cells Using Aptamers
  108. Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells
  109. Cell-Specific Internalization Study of an Aptamer from Whole Cell Selection
  110. Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells
  111. Design, synthesis and screening of antisense peptide based combinatorial peptide libraries towards an aromatic region of SARS-CoV
  112. Aptamer Directly Evolved from Live Cells Recognizes Membrane Bound Immunoglobin Heavy Mu Chain in Burkitt's Lymphoma Cells
  113. Selection of Aptamers for Molecular Recognition and Characterization of Cancer Cells
  114. Aptamers Evolved from Cultured Cancer Cells Reveal Molecular Differences of Cancer Cells in Patient Samples
  115. Optimization and Modifications of Aptamers Selected from Live Cancer Cell Lines
  116. Aptamer-Conjugated Nanoparticles for the Collection and Detection of Multiple Cancer Cells
  117. Uniform-sized molecularly imprinted polymer for metsulfuron-methyl by one-step swelling and polymerization method
  118. Aptamers evolved from live cells as effective molecular probes for cancer study
  119. Monolithic molecularly imprinted polymer for sulfamethoxazole and molecular recognition properties in aqueous mobile phase
  120. Aptamer-Conjugated Nanoparticles for Selective Collection and Detection of Cancer Cells
  121. QCM–FIA with PGMA coating for dynamic interaction study of heparin and antithrombin III
  122. A novel matrix for high performance affinity chromatography and its application in the purification of antithrombin III
  123. Cancer Cell Proteomics Using Molecular Aptamers
  124. Preparation and evaluation of uniform-sized molecularly imprinted polymer beads used for the separation of sulfamethazine
  125. Screening of inhibitors for influenza A virus using high-performance affinity chromatography and combinatorial peptide libraries
  126. Acetylcholine release in the hippocampus during the operant conditioned reflex and the footshock stimulus in rats
  127. Quartz crystal biosensor for real-time kinetic analysis of interaction between human TNF-α and monoclonal antibodies
  128. Real time kinetic analysis of the interaction between immunoglobulin G and histidine using quartz crystal microbalance biosensor in solution
  129. Quartz crystal biosensor for real-time monitoring of molecular recognition between protein and small molecular medicinal agents
  130. Novel sulfamethazine ligand used for one-step purification of immunoglobulin G from human plasma
  131. Analysis of glucose and lactate in hippocampal dialysates of rats during the operant conditioned reflex using microdialysis
  132. Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress
  133. Improved method for the routine determination of acetylcholine and choline in brain microdialysate using a horseradish peroxidase column as the immobilized enzyme reactor
  134. Simple PbII fluorescent probe based on PbII-catalyzed hydrolysis of phosphodiester
  135. A new type of capillary column for open-tubular electrochromatography
  136. Analysis of glucose and lactate in dialysate from hypothalamus of rats after exhausting swimming using microdialysis
  137. Derivatization and Fluorescence Detection of Amino Acids and Peptides with 9-Fluorenylmethyl Chloroformate on the Surface of a Solid Adsorbent
  138. New method for high-performance liquid chromatographic separation and fluorescence detection of ginsenosides
  139. Three novel high performance affinity chromatographic media for the separation of antithrombin III from human plasma