All Stories

  1. Simultaneous Monitoring of Mitochondrial Temperature and ATP Fluctuation Using Fluorescent Probes in Living Cells

    Article • Analytical Chemistry, October 2018, American Chemical Society (ACS)

    Professor Dihua Shangguan

  2. Thiazole Orange-Modified Carbon Dots for Ratiometric Fluorescence Detection of G-Quadruplex and Double-Stranded DNA

    Article • ACS Applied Materials & Interfaces, July 2018, American Chemical Society (ACS)

    Professor Dihua Shangguan

  3. Oxidative degradation of polyamines by serum supplement causes cytotoxicity on cultured cells

    Article • Scientific Reports, July 2018, Springer Science + Business Media

    Professor Dihua Shangguan

  4. Flow Cytometric Bead Sandwich Assay Based on a Split Aptamer

    Article • ACS Applied Materials & Interfaces, January 2018, American Chemical Society (ACS)

    Professor Dihua Shangguan

  5. Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in Vivo

    Article • Journal of the American Chemical Society, December 2017, American Chemical Society (ACS)

    Professor Dihua Shangguan

  6. Triplex-quadruplex structural scaffold: a new binding structure of aptamer

    Article • Scientific Reports, November 2017, Nature

    Professor Dihua Shangguan

  7. Quinacridone derivative as a new photosensitizer: Photodynamic effects in cells and in vivo

    Article • Dyes and Pigments, October 2017, Elsevier

    Professor Dihua Shangguan

  8. Dicyanomethylene Substituted Benzothiazole Squaraines: The Efficiency of Photodynamic Therapy In Vitro and In Vivo

    Article • EBioMedicine, September 2017, Elsevier

    Professor Dihua Shangguan

  9. Detection of G-Quadruplex Structures Formed by G-Rich Sequences from Rice Genome and Transcriptome Using Combined Probes

    Article • Analytical Chemistry, July 2017, American Chemical Society (ACS)

    Professor Dihua Shangguan

  10. Development of squaraine based G-quadruplex ligands using click chemistry

    Article • Scientific Reports, July 2017, Nature

    Professor Dihua Shangguan

  11. Microbead-Based Platform for Multiplex Detection of DNA and Protein

    Article • ACS Applied Materials & Interfaces, March 2017, American Chemical Society (ACS)

    Professor Dihua Shangguan

  12. Multifunctional hard-shelled microbubbles for differentiating imaging, cavitation and drug release by ultrasound

    Article • RSC Advances, January 2017, Royal Society of Chemistry

    Professor Dihua Shangguan

  13. Ratiometric Fluorescent Biosensing of Hydrogen Peroxide and Hydroxyl Radical in Living Cells with Lysozyme–Silver Nanoclusters: Lysozyme as Stabilizing Ligand and Fluorescence Signal Unit

    Article • Analytical Chemistry, November 2016, American Chemical Society (ACS)

    Professor Dihua Shangguan

  14. A Protease-Activated Ratiometric Fluorescent Probe for pH-Mapping of Malignant Tumor

    Article • Advances in Science and Technology, October 2016, Trans Tech Publications

    Professor Dihua Shangguan, Dr Wensheng Yang

  15. A Cyanine Dye to Probe Mitophagy: Simultaneous Detection of Mitochondria and Autolysosomes in Live Cells

    Article • Journal of the American Chemical Society, September 2016, American Chemical Society (ACS)

    Professor Dihua Shangguan

  16. Interaction of hypericin with guanine-rich DNA: Preferential binding to parallel G-Quadruplexes

    Article • Dyes and Pigments, May 2016, Elsevier

    Professor Dihua Shangguan

  17. A Bis(methylpiperazinylstyryl)phenanthroline as a Fluorescent Ligand for G-Quadruplexes

    Article • Chemistry - A European Journal, March 2016, Wiley

    Professor Dihua Shangguan

  18. Intercellular Connections Related to Cell-Cell Crosstalk Specifically Recognized by an Aptamer

    Article • Angewandte Chemie International Edition, February 2016, Wiley

    Professor Dihua Shangguan

  19. Intercellular Connections Related to Cell-Cell Crosstalk Specifically Recognized by an Aptamer

    Article • Angewandte Chemie, February 2016, Wiley

    Professor Dihua Shangguan

  20. Activity Enhancement of G-Quadruplex/Hemin DNAzyme by Flanking d(CCC)

    Article • Chemistry - A European Journal, January 2016, Wiley

    Professor Dihua Shangguan

  21. Generating Cell Targeting Aptamers for Nanotheranostics Using Cell-SELEX

    Article • Theranostics, January 2016, Ivyspring International Publisher

    Professor Dihua Shangguan

  22. DNA interaction, cellular localization and cytotoxicity of quinacridone derivatives

    Article • Dyes and Pigments, October 2015, Elsevier

    Professor Dihua Shangguan

  23. Facile Phase Transfer and Surface Biofunctionalization of Hydrophobic Nanoparticles Using Janus DNA Tetrahedron Nanostructures

    Article • Journal of the American Chemical Society, September 2015, American Chemical Society (ACS)

    Professor Dihua Shangguan

  24. Facile Discovery of Cell-Surface Protein Targets of Cancer Cell Aptamers

    Article • Molecular & Cellular Proteomics, July 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dihua Shangguan

  25. Protease-Activated Ratiometric Fluorescent Probe for pH Mapping of Malignant Tumors

    Article • ACS Nano, March 2015, American Chemical Society (ACS)

    Professor Dihua Shangguan

  26. Ultra-high-performance liquid chromatography electrospray ionization tandem mass spectrometry for accurate analysis of glycerophospholipids and sphingolipids in drug resistance tumor cells

    Article • Journal of Chromatography A, February 2015, Elsevier

    Professor Dihua Shangguan

  27. Visible-light-induced cleavage of 4-α-amino acid substituted naphthalimides and its application in DNA photocleavage

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Professor Dihua Shangguan

  28. Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides

    Article • Chemical Science, January 2015, Royal Society of Chemistry

    Professor Dihua Shangguan

  29. Cell-SELEX: Aptamer Selection Against Whole Cells

    Article • January 2015, Springer Science + Business Media

    Professor Dihua Shangguan

  30. Ratiometric fluorescent silver nanoclusters for the determination of mercury and copper ions

    Article • Analytical Methods, January 2015, Royal Society of Chemistry

    Professor Dihua Shangguan

  31. Interaction of bisbenzimidazole-substituted carbazole derivatives with G-quadruplexes and living cells

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Professor Dihua Shangguan

  32. Cell-SELEX-based selection of aptamers that recognize distinct targets on metastatic colorectal cancer cells

    Article • Biomaterials, August 2014, Elsevier

    Professor Dihua Shangguan

  33. Dicyanomethylene-Functionalized Squaraine as a Highly Selective Probe for Parallel G-Quadruplexes

    Article • Analytical Chemistry, July 2014, American Chemical Society (ACS)

    Professor Dihua Shangguan

  34. DNA Aptamer Evolved by Cell-SELEX for Recognition of Prostate Cancer

    Article • PLoS ONE, June 2014, PLOS

    Professor Dihua Shangguan

  35. Carbon Dots Based Dual-Emission Silica Nanoparticles as a Ratiometric Nanosensor for Cu 2+

    Article • Analytical Chemistry, March 2014, American Chemical Society (ACS)

    Professor Dihua Shangguan

  36. Mass Spectrometric Proteomics Reveals that Nuclear Protein Positive Cofactor PC4 Selectively Binds to Cross-Linked DNA by a trans -Platinum Anticancer Complex

    Article • Journal of the American Chemical Society, February 2014, American Chemical Society (ACS)

    Professor Dihua Shangguan

  37. Fluorescence Light-Up Probe for Parallel G-Quadruplexes

    Article • Analytical Chemistry, January 2014, American Chemical Society (ACS)

    Professor Dihua Shangguan

  38. Activity enhancement of G-quadruplex/hemin DNAzyme by spermine

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Professor Dihua Shangguan

  39. Exact tailoring of an ATP controlled streptavidin binding aptamer

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Professor Dihua Shangguan

  40. Effects of side chains on DNA binding, cell permeability, nuclear localization and cytotoxicity of 4-aminonaphthalimides

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Dihua Shangguan

  41. A label-free electrochemical biosensor based on a DNA aptamer against codeine

    Article • Analytica Chimica Acta, July 2013, Elsevier

    Professor Dihua Shangguan

  42. One-step real time RT-PCR for detection of microRNAs

    Article • Talanta, June 2013, Elsevier

    Professor Dihua Shangguan

  43. General Cell-Binding Activity of Intramolecular G-Quadruplexes with Parallel Structure

    Article • PLoS ONE, April 2013, PLOS

    Professor Dihua Shangguan

  44. G-quadruplex DNA aptamers for zeatin recognizing

    Article • Biosensors and Bioelectronics, March 2013, Elsevier

    Professor Dihua Shangguan

  45. A turn-on fluorescent sensor for zinc and cadmium ions based on perylene tetracarboxylic diimide

    Article • The Analyst, January 2013, Royal Society of Chemistry

    Professor Dihua Shangguan

  46. Rational design of Hg2+controlled streptavidin-binding aptamer

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Professor Dihua Shangguan

  47. A guanidine derivative of naphthalimide with excited-state deprotonation coupled intramolecular charge transfer properties and its application

    Article • Journal of Materials Chemistry C, January 2013, Royal Society of Chemistry

    Professor Dihua Shangguan

  48. A pH sensitive ratiometric fluorophore and its application for monitoring the intracellular and extracellular pHs simultaneously

    Article • Journal of Materials Chemistry B, January 2013, Royal Society of Chemistry

    Professor Dihua Shangguan

  49. Specific interactions between adenosine and streptavidin/avidin

    Article • Bioorganic & Medicinal Chemistry Letters, December 2012, Elsevier

    Professor Dihua Shangguan

  50. Functional-Group Specific Aptamers Indirectly Recognizing Compounds with Alkyl Amino Group

    Article • Analytical Chemistry, September 2012, American Chemical Society (ACS)

    Professor Dihua Shangguan

  51. Selective isolation of G-quadruplexes by affinity chromatography

    Article • Journal of Chromatography A, July 2012, Elsevier

    Professor Dihua Shangguan

  52. PEG-urokinase nanogels with enhanced stability and controllable bioactivity

    Article • Soft Matter, January 2012, Royal Society of Chemistry

    Dr Xiaozhong Qu, Professor Dihua Shangguan

  53. Thermal responsive fluorescent block copolymer for intracellular temperature sensing

    Article • Journal of Materials Chemistry, January 2012, Royal Society of Chemistry

    Professor Dihua Shangguan

  54. Characterization of G-Quadruplex/Hemin Peroxidase: Substrate Specificity and Inactivation Kinetics

    Article • Chemistry - A European Journal, November 2011, Wiley

    Professor Dihua Shangguan

  55. G-quadruplex DNA aptamers generated for systemin

    Article • Bioorganic & Medicinal Chemistry, July 2011, Elsevier

    Professor Dihua Shangguan

  56. Characterization and application of a DNA aptamer binding to l-tryptophan

    Article • The Analyst, January 2011, Royal Society of Chemistry

    Professor Dihua Shangguan

  57. Mercury(ii)-mediated formation of imide-Hg-imide complexes

    Article • Dalton Transactions, January 2011, Royal Society of Chemistry

    Professor Dihua Shangguan

  58. Silencing of PTK7 in Colon Cancer Cells: Caspase-10-Dependent Apoptosis via Mitochondrial Pathway

    Article • PLoS ONE, November 2010, PLOS

    Professor Dihua Shangguan

  59. Development of DNA aptamers using Cell-SELEX

    Article • Nature Protocols, June 2010, Springer Science + Business Media

    Professor Dihua Shangguan

  60. Cancer Cell Proteomics using Molecular Aptamers

    Article • March 2010, Wiley

    Professor Dihua Shangguan

  61. Conservative secondary structure motif of streptavidin-binding aptamers generated by different laboratories

    Article • Bioorganic & Medicinal Chemistry, March 2010, Elsevier

    Professor Dihua Shangguan

  62. Bifunctional combined aptamer for simultaneous separation and detection of thrombin

    Article • Biosensors and Bioelectronics, February 2010, Elsevier

    Professor Dihua Shangguan

  63. Visual Detection of Hg2+ with High Selectivity Using Thymine Modified Gold Nanoparticles

    Article • Analytical Sciences, January 2010, Japan Society for Analytical Chemistry

    Professor Dihua Shangguan

  64. Specific DNA G-quadruplexes bind to ethanolamines

    Article • Biopolymers, October 2009, Wiley

    Professor Dihua Shangguan

  65. General Peroxidase Activity of G-Quadruplex−Hemin Complexes and Its Application in Ligand Screening

    Article • Biochemistry, August 2009, American Chemical Society (ACS)

    Professor Dihua Shangguan

  66. Highly Selective Phthalocyanine−Thymine Conjugate Sensor for Hg 2+ Based on Target Induced Aggregation

    Article • Analytical Chemistry, May 2009, American Chemical Society (ACS)

    Professor Dihua Shangguan

  67. Specific mercury(II) adsorption by thymine-based sorbent

    Article • Talanta, April 2009, Elsevier

    Professor Dihua Shangguan

  68. Molecular Assembly of an Aptamer-Drug Conjugate for Targeted Drug Delivery to Tumor Cells

    Article • ChemBioChem, March 2009, Wiley

    Professor Dihua Shangguan

  69. A label-free fluorescence sensor for probing the interaction of oligonucleotides with target molecules

    Article • Analytica Chimica Acta, February 2009, Elsevier

    Professor Dihua Shangguan

  70. Molecular recognition of acute myeloid leukemia using aptamers

    Article • Leukemia, January 2009, Springer Science + Business Media

    Professor Dihua Shangguan

  71. Recognition of subtype non-small cell lung cancer by DNA aptamers selected from living cells

    Article • The Analyst, January 2009, Royal Society of Chemistry

    Professor Dihua Shangguan

  72. Fluorescent Aptamer Sensors

    Article • January 2009, Springer Science + Business Media

    Professor Dihua Shangguan

  73. Molecular Recognition of Small-Cell Lung Cancer Cells Using Aptamers

    Article • ChemMedChem, June 2008, Wiley

    Professor Dihua Shangguan

  74. Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells

    Article • Journal of Proteome Research, May 2008, American Chemical Society (ACS)

    Professor Dihua Shangguan

  75. Cell-Specific Internalization Study of an Aptamer from Whole Cell Selection

    Article • Chemistry - A European Journal, February 2008, Wiley

    Professor Dihua Shangguan

  76. Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells

    Article • Analytical Chemistry, February 2008, American Chemical Society (ACS)

    Professor Dihua Shangguan

  77. Design, synthesis and screening of antisense peptide based combinatorial peptide libraries towards an aromatic region of SARS-CoV

    Article • Journal of Molecular Recognition, January 2008, Wiley

    Professor Dihua Shangguan

  78. Aptamer Directly Evolved from Live Cells Recognizes Membrane Bound Immunoglobin Heavy Mu Chain in Burkitt's Lymphoma Cells

    Article • Molecular & Cellular Proteomics, September 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dihua Shangguan

  79. Selection of Aptamers for Molecular Recognition and Characterization of Cancer Cells

    Article • Analytical Chemistry, July 2007, American Chemical Society (ACS)

    Professor Dihua Shangguan

  80. Aptamers Evolved from Cultured Cancer Cells Reveal Molecular Differences of Cancer Cells in Patient Samples

    Article • Clinical Chemistry, June 2007, Oxford University Press (OUP)

    Professor Dihua Shangguan

  81. Optimization and Modifications of Aptamers Selected from Live Cancer Cell Lines

    Article • ChemBioChem, April 2007, Wiley

    Professor Dihua Shangguan

  82. Aptamer-Conjugated Nanoparticles for the Collection and Detection of Multiple Cancer Cells

    Article • Analytical Chemistry, April 2007, American Chemical Society (ACS)

    Professor Dihua Shangguan

  83. Uniform-sized molecularly imprinted polymer for metsulfuron-methyl by one-step swelling and polymerization method

    Article • Talanta, February 2007, Elsevier

    Professor Dihua Shangguan

  84. Aptamers evolved from live cells as effective molecular probes for cancer study

    Article • Proceedings of the National Academy of Sciences, August 2006, Proceedings of the National Academy of Sciences

    Professor Dihua Shangguan

  85. Monolithic molecularly imprinted polymer for sulfamethoxazole and molecular recognition properties in aqueous mobile phase

    Article • Analytica Chimica Acta, July 2006, Elsevier

    Professor Dihua Shangguan

  86. Aptamer-Conjugated Nanoparticles for Selective Collection and Detection of Cancer Cells

    Article • Analytical Chemistry, May 2006, American Chemical Society (ACS)

    Professor Dihua Shangguan

  87. QCM–FIA with PGMA coating for dynamic interaction study of heparin and antithrombin III

    Article • Biosensors and Bioelectronics, July 2005, Elsevier

    Professor Dihua Shangguan

  88. A novel matrix for high performance affinity chromatography and its application in the purification of antithrombin III

    Article • Journal of Chromatography B, February 2005, Elsevier

    Professor Dihua Shangguan

  89. Cancer Cell Proteomics Using Molecular Aptamers

    Article • January 2005, Wiley

    Professor Dihua Shangguan

  90. Preparation and evaluation of uniform-sized molecularly imprinted polymer beads used for the separation of sulfamethazine

    Article • Biomedical Chromatography, January 2005, Wiley

    Professor Dihua Shangguan

  91. Screening of inhibitors for influenza A virus using high-performance affinity chromatography and combinatorial peptide libraries

    Article • Journal of Chromatography A, January 2005, Elsevier

    Professor Dihua Shangguan

  92. Acetylcholine release in the hippocampus during the operant conditioned reflex and the footshock stimulus in rats

    Article • Neuroscience Letters, October 2004, Elsevier

    Professor Dihua Shangguan

  93. Quartz crystal biosensor for real-time kinetic analysis of interaction between human TNF-α and monoclonal antibodies

    Article • Sensors and Actuators B Chemical, May 2004, Elsevier

    Professor Dihua Shangguan

  94. Real time kinetic analysis of the interaction between immunoglobulin G and histidine using quartz crystal microbalance biosensor in solution

    Article • Biosensors and Bioelectronics, October 2003, Elsevier

    Professor Dihua Shangguan

  95. Quartz crystal biosensor for real-time monitoring of molecular recognition between protein and small molecular medicinal agents

    Article • Biosensors and Bioelectronics, October 2003, Elsevier

    Professor Dihua Shangguan

  96. Novel sulfamethazine ligand used for one-step purification of immunoglobulin G from human plasma

    Article • Journal of Chromatography B, July 2003, Elsevier

    Professor Dihua Shangguan

  97. Analysis of glucose and lactate in hippocampal dialysates of rats during the operant conditioned reflex using microdialysis

    Article • Neurochemistry International, July 2003, Elsevier

    Professor Dihua Shangguan

  98. Hyperoxia caused by microdialysis perfusion decreased striatal monoamines: involvement of oxidative stress

    Article • Neurochemistry International, May 2003, Elsevier

    Professor Dihua Shangguan

  99. Improved method for the routine determination of acetylcholine and choline in brain microdialysate using a horseradish peroxidase column as the immobilized enzyme reactor

    Article • Journal of Chromatography B, May 2003, Elsevier

    Professor Dihua Shangguan

  100. Simple PbII fluorescent probe based on PbII-catalyzed hydrolysis of phosphodiester

    Article • Biopolymers, January 2003, Wiley

    Professor Dihua Shangguan

  101. A new type of capillary column for open-tubular electrochromatography

    Article • Electrophoresis, September 2002, Wiley

    Professor Dihua Shangguan

  102. Analysis of glucose and lactate in dialysate from hypothalamus of rats after exhausting swimming using microdialysis

    Article • Biomedical Chromatography, January 2002, Wiley

    Professor Dihua Shangguan

  103. Derivatization and Fluorescence Detection of Amino Acids and Peptides with 9-Fluorenylmethyl Chloroformate on the Surface of a Solid Adsorbent

    Article • Analytical Chemistry, May 2001, American Chemical Society (ACS)

    Professor Dihua Shangguan

  104. New method for high-performance liquid chromatographic separation and fluorescence detection of ginsenosides

    Article • Journal of Chromatography A, March 2001, Elsevier

    Professor Dihua Shangguan

  105. Three novel high performance affinity chromatographic media for the separation of antithrombin III from human plasma

    Article • Biomedical Chromatography, January 2001, Wiley

    Professor Dihua Shangguan