All Stories

  1. Synthesis of 2-aryl/alkylaminomethyl 17-sulfamate/17-methyl estratrienes and their in vitro cytotoxicity in human cancer cell cultures

    Article • Steroids, July 2026, Elsevier

    Mr Dhatchana Moorthy

  2. A chimeric natriuretic peptide (Ev-NP) inhibits isoproterenol (ISO)-induced hypertrophic growth in in vivo and in vitro models by enhancing cGMP and its downstream signaling targets: In silico docking and binding efficacy analysis with NPR-A and NPR-B ...

    Article • Peptides, May 2026, Elsevier

    Mr Dhatchana Moorthy

  3. Cross-study transcriptomics and machine learning approaches reveal a predictive six-gene panel for hepatocellular carcinoma

    Article • Medicine in Omics, May 2026, Elsevier

    Mr Dhatchana Moorthy

  4. Expression and Regulation of Npr1 Gene Coding for Natriuretic Peptide Receptor-A in Hypertrophied Heart: Mechanisms and Therapeutic Implications

    Article • International Journal of Peptide Research and Therapeutics, February 2026, Springer Science + Business Media

    Mr Dhatchana Moorthy

  5. In silico design and development of benzyl piperazine conjugates for targeting choline esterase pathway in Alzheimer's disease

    Article • In Silico Research in Biomedicine, January 2026, Elsevier

    Mr Dhatchana Moorthy

  6. Computational investigation and synthesis of 6-chlorocoumarin-oxadiazole hybrids for identifying newer candidates against Alzheimer's disease using multi-target strategies

    Article • Letters in Drug Design & Discovery, November 2025, Elsevier

    Mr Dhatchana Moorthy

  7. Integrative Machine Learning Approaches to Identify and Validate Gene Biomarkers for Early Detection of Hepatocellular Carcinoma

    Article • December 2024, Springer Science + Business Media

    Mr Dhatchana Moorthy

  8. An Efficient Synthesis of Novel Aminothiazolylacetamido-Substituted 3,5-Bis(arylidene)-4-piperidone Derivatives and Their Cytotoxicity Studies

    Article • ACS Omega, June 2024, American Chemical Society (ACS)

    Mr Dhatchana Moorthy

  9. C-Type Natriuretic Peptide (CNP) Induces Cell Death and Sensitizes the Effect of Cisplatin in Human Non-small Cell Lung Cancer Cells (A549)

    Article • International Journal of Peptide Research and Therapeutics, June 2022, Springer Science + Business Media

    Mr Dhatchana Moorthy

  10. Divergent Synthesis and Evaluation of the in vitro Cytotoxicity Profiles of 3,4‐Ethylenedioxythiophenyl‐2‐propen‐1‐one Analogues

    Article • ChemMedChem, July 2019, Wiley

    Mr Dhatchana Moorthy

  11. Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage

    Article • PLOS One, September 2018, PLOS

    Mr Dhatchana Moorthy

  12. Arylidenedibenzoxazepines

    Article • Letters in Organic Chemistry, March 2018, Bentham Science Publishers

    Mr Dhatchana Moorthy, pr kathiravan

  13. Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues

    Article • Journal of Medicinal Chemistry, January 2018, American Chemical Society (ACS)

    Mr Dhatchana Moorthy

  14. Synthesis of novel bis-allyloxy and hydroxypropoxy derivatives of 4, 5-diaryl thiophene-2-carboxylic acid and their biological evaluation

    Article • Journal of Chemical Sciences, May 2017, Springer Science + Business Media

    Mr Dhatchana Moorthy

  15. Synthesis, in vitro anti-inflammatory activity and molecular docking studies of novel 4,5-diarylthiophene-2-carboxamide derivatives

    Article • Journal of Chemical Sciences, December 2016, Springer Science + Business Media

    Mr Dhatchana Moorthy

  16. Synthesis of Thia-Analogues of Calothrixin B Involving FeCl3-Mediated Domino Reaction

    Article • Synlett, September 2016, Thieme Publishing Group

    Mr Dhatchana Moorthy

  17. Functional characterization of Candida albicans Hos2 histone deacetylase

    Article • F1000Research, July 2014, F1000Research

    Dr Maneesh Paul Satyaseela, Mr Dhatchana Moorthy

  18. New Drug Discovery and Infectious Diseases

    Article • F1000Research, November 2013, Faculty of 1000, Ltd.

    Dr Maneesh Paul Satyaseela, Dr Karthikeyan Ganesan, Mr Dhatchana Moorthy

  19. Synthesis of 2-substituted 17β-hydroxy/17-methylene estratrienes and their in vitro cytotoxicity in human cancer cell cultures

    Article • Steroids, December 2011, Elsevier

    Mr Dhatchana Moorthy

  20. Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity

    Article • Bioorganic & Medicinal Chemistry Letters, July 2010, Elsevier

    Mr Dhatchana Moorthy

  21. DNA Damage-induced Expression of p53 Suppresses Mitotic Checkpoint Kinase hMps1

    Article • Journal of Biological Chemistry, January 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Mr Dhatchana Moorthy

  22. The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein

    Article • Oncogene, September 2004, Nature

    Mr Dhatchana Moorthy