All Stories

  1. How large must a dose‐optimization trial be?

    Article • CPT Pharmacometrics & Systems Pharmacology, October 2023, Wiley

    Dr David C Norris

  2. Patient-Centered, Physician-Investigator Friendly Pragmatic Phase I/II Trial Designs—The 4P Model

    Article • Mayo Clinic Proceedings, November 2020, Elsevier

    Dr David C Norris

  3. Comment on Wages et al, Coherence principles in interval-based dose finding. Pharmaceutical Statistics 2019, doi:10.1002/pst.1974

    Article • Pharmaceutical Statistics, March 2020, Wiley

    Dr David C Norris

  4. Ethical Review and Methodologic Innovation in Phase 1 Cancer Trials

    Article • JAMA Pediatrics, April 2019, American Medical Association (AMA)

    Dr David C Norris

  5. Clinicians must regain control over phase 1 cancer combination-therapy trials

    Article • July 2018, Cold Spring Harbor Laboratory Press

    Dr David C Norris

  6. The conduct of most first-in-human oncology drug trials is conceptually incoherent, and unethical.

    Article • December 2017, Cold Spring Harbor Laboratory Press

    Dr David C Norris

  7. One-size-fits-all dosing in oncology wastes money, innovation and lives

    Article • Drug Discovery Today, November 2017, Elsevier

    Dr David C Norris

  8. Dose Titration Algorithm Tuning (DTAT) should supersede ‘the’ Maximum Tolerated Dose (MTD) in oncology dose-finding trials

    Article • F1000Research, July 2017, Faculty of 1000, Ltd.

    Dr David C Norris

  9. One-size-fits-all dosing of cancer treatment drugs: How much does it cost society?

    Article • June 2017, Cold Spring Harbor Laboratory Press

    Dr David C Norris

  10. A new concept may help us at last abandon one-size-fits-all dosing of cancer treatment drugs

    Article • F1000Research, March 2017, Faculty of 1000, Ltd.

    Dr David C Norris

  11. Dose Titration Algorithm Tuning (DTAT) should supersede the Maximum Tolerated Dose (MTD) concept in oncology dose-finding trials

    Article • F1000Research, February 2017, Faculty of 1000, Ltd.

    Dr David C Norris

  12. Casting a realist's eye on the real world of medicine: Against Anjum's ontological relativism

    Article • Journal of Evaluation in Clinical Practice, January 2017, Wiley

    Dr David C Norris

  13. Challenging an analysis of poverty, opportunity and PTSD in inner-city youth

    Article • F1000Research, May 2016, Faculty of 1000, Ltd.

    Dr David C Norris, Andy R Wilson

  14. No Credible Alternative To 'The Basic Flaw'

    Article • Health Affairs, September 2014, Health Affairs

    Dr David C Norris

  15. Housing Mobility and Adolescent Mental Health

    Article • JAMA, July 2014, American Medical Association (AMA)

    Dr David C Norris

  16. Financial Incentives to Control Hypertension in Patients

    Article • JAMA, January 2014, American Medical Association (AMA)

    Dr David C Norris

  17. Origins of Diagnostic Error

    Article • JAMA Internal Medicine, November 2013, American Medical Association (AMA)

    Dr David C Norris

  18. Racial Disparities In Hospital Selection

    Article • Health Affairs, October 2013, Health Affairs

    Dr David C Norris

  19. Community-Acquired Pneumonia and Proton Pump Inhibitors

    Article • Journal of General Internal Medicine, April 2013, Springer Science + Business Media

    Dr David C Norris