All Stories

  1. Structure-based design of nanobodies that inhibit seeding of Alzheimer’s patient–extracted tau fibrils

    Article • Proceedings of the National Academy of Sciences, October 2023, Proceedings of the National Academy of Sciences

    David Eisenberg

  2. Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils

    Article • Proceedings of the National Academy of Sciences, February 2023, Proceedings of the National Academy of Sciences

    David Eisenberg

  3. De novo designed protein inhibitors of amyloid aggregation and seeding

    Article • Proceedings of the National Academy of Sciences, August 2022, Proceedings of the National Academy of Sciences

    David Eisenberg

  4. Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation

    Article • Proceedings of the National Academy of Sciences, April 2022, Proceedings of the National Academy of Sciences

    David Eisenberg

  5. The formation, function and regulation of amyloids: insights from structural biology

    Article • Journal of Internal Medicine, May 2016, Wiley

    David Eisenberg

  6. Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta

    Article • eLife, July 2013, eLife

    Michael Patrick Hughes, David Eisenberg