All Stories

  1. Ionic selectivity and thermal adaptations within the voltage-gated sodium channel family of alkaliphilic Bacillus
  2. The TRPM7 Chanzyme Is Cleaved to Release a Chromatin-Modifying Kinase
  3. Therapeutic Restoration of Spinal Inhibition via Druggable Enhancement of Potassium-Chloride Cotransporter KCC2–Mediated Chloride Extrusion in Peripheral Neuropathic Pain
  4. Structurally Distinct Ca2+ Signaling Domains of Sperm Flagella Orchestrate Tyrosine Phosphorylation and Motility
  5. Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1
  6. Direct recording and molecular identification of the calcium channel of primary cilia
  7. Primary cilia are specialized calcium signalling organelles
  8. TRPV3 Channels Mediate Strontium-Induced Mouse-Egg Activation
  9. The mother of all endocytosis
  10. Sperm BerserKers
  11. Role of the C-terminal domain in the structure and function of tetrameric sodium channels
  12. MCU encodes the pore conducting mitochondrial calcium currents
  13. Rheotaxis Guides Mammalian Sperm
  14. mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State
  15. Properties of the Mitochondrial Permeability Transition in Drosophila S2R+ Cells
  16. Sperm Patch-Clamp
  17. Catsper Channel Organizes and Regulates Calcium Signaling Molecules in Spermatozoa
  18. The Ion Channel-Kinase, TRPM7, is Required for Cardiac Automaticity
  19. Analysis of the selectivity filter of the voltage-gated sodium channel NavRh
  20. Anion-Sensitive Fluorophore Identifies the Drosophila Swell-Activated Chloride Channel in a Genome-Wide RNA Interference Screen
  21. TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes
  22. TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis
  23. Controlled delivery of bioactive molecules into live cells using the bacterial mechanosensitive channel MscL
  24. Cleavage of TRPM7 Releases the Kinase Domain from the Ion Channel and Regulates Its Participation in Fas-Induced Apoptosis
  25. Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
  26. The Control of Male Fertility by Spermatozoan Ion Channels
  27. The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke
  28. Drosophila Bestrophin 1 is a Swell Activated Chloride Channel
  29. A Thermodynamic Framework for Understanding Temperature-Sensitivity in TRP Channels
  30. Super-Resolution Imaging Reveals a Multi-Array Arrangement of Catsper Channel on the Sperm Tail
  31. Novel Na+-Selective Channels in the Lysosome
  32. Cardiac-Targeted TRPM7 Deletion Induces Heart Block and Cardiomyopathy via Disrupted Embryonic Ventricular Development
  33. A novel Gene Required for Male Fertility and Functional Catsper Channel Formation in Spermatozoa
  34. A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa
  35. TRPM7, the Mg2+ Inhibited Channel and Kinase
  36. An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1
  37. Targeted Cytosolic Delivery of Cell-Impermeable Compounds by Nanoparticle-Mediated, Light-Triggered Endosome Disruption
  38. TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation
  39. A Single S4 Arginine is Sufficient for Voltage Sensitivity in the Hv1 Proton Channel
  40. Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca2+/H+ Antiporter
  41. Essential Role for TRPC5 in Amygdala Function and Fear-Related Behavior
  42. Intracellular calcium strongly potentiates agonist-activated TRPC5 channels
  43. A STIMulus Package Puts Orai Calcium Channels to Work
  44. Voltage and proton gradient sensing in Hv1 proton channels
  45. H+ Permeation in Hv1 Voltage-gated Proton Channels
  46. Phenotyping sensory nerve endings in vitro in the mouse
  47. Evolutionary Genomics Reveals Lineage-Specific Gene Loss and Rapid Evolution of a Sperm-Specific Ion Channel Complex: CatSpers and CatSperβ
  48. The MUPP1–SynGAPα protein complex does not mediate activity-induced LTP
  49. Citral Sensing by TRANSient Receptor Potential Channels in Dorsal Root Ganglion Neurons
  50. Ion channels that control fertility in mammalian spermatozoa
  51. Calcium Signaling
  52. SnapShot: Mammalian TRP Channels
  53. Developmental Origin of a Bipotential Myocardial and Smooth Muscle Cell Precursor in the Mammalian Heart
  54. The TRPM7 Ion Channel Functions in Cholinergic Synaptic Vesicles and Affects Transmitter Release
  55. Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport
  56. Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels
  57. A voltage-gated proton-selective channel lacking the pore domain
  58. Whole-cell patch-clamp measurements of spermatozoa reveal an alkaline-activated Ca2+ channel
  60. International Union of Pharmacology. XLIX. Nomenclature and Structure-Function Relationships of Transient Receptor Potential Channels
  61. International Union of Pharmacology. L. Nomenclature and Structure-Function Relationships of CatSper and Two-Pore Channels
  62. TRP channels and mice deficient in TRP channels
  63. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
  64. SynGAP-MUPP1-CaMKII Synaptic Complexes Regulate p38 MAP Kinase Activity and NMDA Receptor- Dependent Synaptic AMPA Receptor Potentiation
  65. Rapid vesicular translocation and insertion of TRP channels
  66. TRP ion channels in the nervous system
  67. A Spontaneous, Recurrent Mutation in Divalent Metal Transporter-1 Exposes a Calcium Entry Pathway
  68. The mitochondrial calcium uniporter is a highly selective ion channel
  69. Intracellular Signaling and Regulation of Cardiac Ion Channels
  70. TRP channels as cellular sensors
  71. Symmetry, Selectivity, and the 2003 Nobel Prize
  72. International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels: Transient Receptor Potential Channels
  73. The NMDA Receptor Is Coupled to the ERK Pathway by a Direct Interaction between NR2B and RasGRF1
  74. TRPC5 is a regulator of hippocampal neurite length and growth cone morphology
  75. Mechanism of Persistent Protein Kinase D1 Translocation and Activation
  76. Real-Time Imaging of Nuclear Permeation by EGFP in Single Intact Cells
  77. Modified herpes simplex virus delivery of enhanced GFP into the central nervous system
  78. Sorting out MIC, TRP, and CRAC Ion Channels
  79. TRPV3 is a calcium-permeable temperature-sensitive cation channel
  80. The TRPM7 channel is inactivated by PIP2 hydrolysis
  81. SIGNAL TRANSDUCTION: Hot and Cold TRP Ion Channels
  82. Structural characterization of the mouse Girk genes
  83. A sperm ion channel required for sperm motility and male fertility
  84. The trp ion channel family
  85. Evaluation of the role of IKAChin atrial fibrillation using a mouse knockout model
  86. TRPC1 and TRPC5 Form a Novel Cation Channel in Mammalian Brain
  87. Excitability and Conduction
  88. How to Lose Your Hippocampus by Working on Chloride Channels
  89. Distinct Ion Channel Classes Are Expressed on the Outer Nuclear Envelope of T- and B-Lymphocyte Cell Lines
  90. Remembering Eva Neer
  91. Conformational Changes of the in Situ Nuclear Pore Complex
  92. Unlocking Family Secrets
  93. Molecular Determinants for Subcellular Localization of PSD-95 with an Interacting K+ Channel
  94. Structure, G Protein Activation, and Functional Relevance of the Cardiac G Protein‐Gated K+ Channel, IKACh
  95. GIRK4 Confers Appropriate Processing and Cell Surface Localization to G-protein-gated Potassium Channels
  96. Chapter 16 G-Protein-Gated Potassium Channels: Implication for the weaver Mouse
  97. Gβγ Binding Increases the Open Time of IKACh: Kinetic Evidence for Multiple Gβγ Binding Sites
  98. Touch Channels Sense Blood Pressure
  99. Not So Funny Anymore
  100. At last, the structure of an ion-selective channel
  101. A Novel Inward Rectifier K+ Channel with Unique Pore Properties
  102. Perspective: The List of Potential Volume-sensitive Chloride Currents Continues to Swell (and Shrink): Table I
  103. Calcium regulation of nuclear pore permeability
  104. Abnormal Heart Rate Regulation in GIRK4 Knockout Mice
  105. Mechanisms of Transmembrane Signaling
  106. Nuclear calcium and the regulation of the nuclear pore complex
  107. Calcium release and influx colocalize to the endoplasmic reticulum
  108. Ion Channels — Basic Science and Clinical Disease
  109. In Memoriam: Fredric S. Fay
  111. Nucleoplasmic and cytoplasmic differences in the fluorescence properties of the calcium indicator Fluo-3
  112. Partial Structure, Chromosome Localization, and Expression of the MouseIclnGene
  113. Intracellular signalling: More jobs for Gβγ
  114. TRP Is Cracked but Is CRAC TRP?
  115. The K+ channel inward rectifier subunits form a channel similar to neuronal G protein‐gated K+ channel
  116. The G-protein nanomachine
  117. Localization and Interaction of Epitope-tagged GIRK1 and CIR Inward Rectifier K + Channel Subunits
  118. Replenishing the stores
  119. G-protein regulation of ion channels
  120. Calcium signaling
  121. Calcium release from the nucleus by InsP3 receptor channels
  122. 1 Intracellular calcium waves
  123. Why testicles are cool
  124. Calcium channels activated by depletion of internal calcium stores in A431 cells
  125. Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel
  126. Direct G Protein Activation of Ion Channels?
  127. Molecular characterization of a swelling-induced chloride conductance regulatory protein, plCIn
  128. Simultaneous Ultraviolet and Visible Excitation Confocal Microscopy
  129. Simultaneous Ultraviolet and Visible Wavelength Confocal Microscopy
  130. [27] G-protein-mediated pathways assayed by electrophysiology and confocal microscopy
  131. Simultaneous Near Ultraviolet and Visible Excitation Confocal Microscopy of Calcium Transients in Xenopus Oocytes
  132. Mutations in G protein-linked receptors: Novel insights on disease
  133. New roles for G-protein (βγ-dimers in transmembrane signalling
  134. Specificity of receptor-G protein interactions: Searching for the structure behind the signal
  135. A mysterious new influx factor?
  136. Fantastic voyagers? Review of B. C. Crandall and James Lewis, Nanotechnology: Research and Perspectives
  137. Reply
  138. α‐Helical distorting substitutions disrupt coupling between m3 muscarinic receptor and G proteins
  139. Calcium waves
  140. Acceleration of intracellular calcium waves in Xenopus oocytes by calcium influx
  141. Calcium wave propagation by calcium-induced calcium release: An unusual excitable system
  142. Cardiac chloride channels
  143. Molecular mechanisms of intracellular calcium excitability in X. laevis oocytes
  144. New mammalian chloride channel identified by expression cloning
  145. Inositol 1,3,4,5-tetrakisphosphate activates an endothelial Ca2+-permeable channel
  146. Signal transduction through G proteins in the cardiac myocyte
  147. Spiral waves and intracellular calcium signalling
  148. Chloride channels in the nuclear membrane
  149. Spiral calcium wave propagation and annihilation in Xenopus laevis oocytes
  150. Subcellular patterns of calcium release determined by G protein-specific residues of muscarinic receptors
  151. Cell Signalling. Noel G. Morgan
  152. Intracellular Regulation of Ion Channels in Cell Membranes
  153. Arachidonic acid and its metabolites in the regulation of G-protein gated K+ channels in atrial myocytes
  154. Structure and Function of G-Protein βγ Subunit
  155. Somatostatin activates an inwardly rectifying K+ channel in neonatal rat atrial cells
  156. Potassium channels in cardiac cells activated by arachidonic acid and phospholipids
  157. G-protein βγ-subunits activate the cardiac muscarinic K+-channel via phospholipase A2
  158. Muscarinic-activated K+ current in bovine aortic endothelial cells.
  159. Roles of G protein subunits in transmembrane signalling
  160. G protein opening of K+ channels
  161. The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart
  162. Potassium channels and conductance in cultured mouse peritoneal macrophages
  163. Voltage-Activated K Channels in Embryonic Chick Heart
  164. Small signal impedance of heart cell membranes
  165. Intercellular Coupling between Embryonic Heart Cell Aggregates
  166. Second-Order Admittance in Squid Axon
  167. Development of electrical coupling and action potential synchrony between paired aggregates of embryonic heart cells
  168. The theoretical small signal impedance of the frog node,Rana pipiens