All Stories

  1. Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

    Article • iNew Medicine, March 2026, Wiley

    Danielle Kamato

  2. Neratinib, a Clinical Drug Treating Breast Cancer, Protects Against Vascular Inflammation and Atherosclerosis

    Article • Circulation Research, February 2026, Wolters Kluwer Health

    Danielle Kamato

  3. The clinical antiprotozoal drug halofuginone promotes weight loss by elevating GDF15 and FGF21

    Article • Science Advances, March 2025, American Association for the Advancement of Science

    Danielle Kamato

  4. Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway

    Article • Journal of Advanced Research, February 2025, Elsevier

    Danielle Kamato

  5. Advances in, and prospects of, 3D preclinical models for skin drug discovery

    Article • Drug Discovery Today, December 2024, Elsevier

    Danielle Kamato

  6. Smad transcription factors as mediators of 7 transmembrane G protein-coupled receptor signalling

    Article • Acta Pharmacologica Sinica, November 2024, Springer Science + Business Media

    Danielle Kamato

  7. Response to retention hypothesis as a source of targets for arterial wall-directed therapies to prevent atherosclerosis: A critical review

    Article • Atherosclerosis, October 2024, Elsevier

    Danielle Kamato

  8. Mechanistic insight: Linking cardiovascular complications of inflammatory bowel disease

    Article • Trends in Cardiovascular Medicine, April 2024, Elsevier

    Danielle Kamato

  9. Transforming growth factor-β receptors: versatile mechanisms of ligand activation

    Article • Acta Pharmacologica Sinica, February 2024, Springer Science + Business Media

    Danielle Kamato

  10. Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Danielle Kamato

  11. Non-Mouse Models of Atherosclerosis: Approaches to Exploring the Translational Potential of New Therapies

    Article • International Journal of Molecular Sciences, October 2022, MDPI AG

    Danielle Kamato

  12. Endothelin‐1 dependent expression of GAG genes involves NOX and p38 mediated Smad linker region phosphorylation

    Article • Clinical and Experimental Pharmacology and Physiology, May 2022, Wiley

    Danielle Kamato

  13. Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic

    Article • Materials Today Advances, March 2022, Elsevier

    Danielle Kamato

  14. Lipopolysaccharide acting via toll-like receptor 4 transactivates the TGF-β receptor in vascular smooth muscle cells

    Article • Cellular and Molecular Life Sciences, February 2022, Springer Science + Business Media

    Danielle Kamato

  15. Endothelin-1 mediated glycosaminoglycan synthesizing gene expression involves NOX-dependent transactivation of the transforming growth factor-β receptor

    Article • Molecular and Cellular Biochemistry, January 2022, Springer Science + Business Media

    Danielle Kamato

  16. Akt acts as a switch for GPCR transactivation of the TGF‐β receptor type 1

    Article • FEBS Journal, December 2021, Wiley

    Danielle Kamato

  17. Lipopolysaccharide Acting Via Toll Like Receptor 4 Transactivates The TGF-β Receptor in Vascular Smooth Muscle cells

    Article • September 2021, Springer Science + Business Media

    Danielle Kamato

  18. YY‐11, a camel milk‐derived peptide, inhibits TGF‐β‐mediated atherogenic signaling in human vascular smooth muscle cells

    Article • Journal of Food Biochemistry, July 2021, Wiley

    Danielle Kamato

  19. Endothelial Dysfunction and Cardiovascular Disease: History and Analysis of the Clinical Utility of the Relationship

    Article • Biomedicines, June 2021, MDPI AG

    Danielle Kamato

  20. Curcumin Inhibits Lysophosphatidic Acid Mediated MCP-1 Expression via Blocking ROCK Signalling

    Article • Molecules, April 2021, MDPI AG

    Danielle Kamato

  21. Targeted Molecular Imaging of Cardiovascular Diseases by Iron Oxide Nanoparticles

    Article • Arteriosclerosis Thrombosis and Vascular Biology, February 2021, Wolters Kluwer Health

    Danielle Kamato

  22. Lysophosphatidic acid receptor 5 transactivation of TGFBR1 stimulates the mRNA expression of proteoglycan synthesizing genes XYLT1 and CHST3

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 2020, Elsevier

    Danielle Kamato

  23. Artemisinin inhibits glycosaminoglycan chain synthesizing gene expression but not proliferation of human vascular smooth muscle cells

    Article • Biochemical and Biophysical Research Communications, November 2020, Elsevier

    Danielle Kamato

  24. Smad2 linker region phosphorylation is an autonomous cell signalling pathway: Implications for multiple disease pathologies

    Article • Biomedicine & Pharmacotherapy, April 2020, Elsevier

    Danielle Kamato

  25. Toll-like Receptor 4 Stimulates Gene Expression via Smad2 Linker Region Phosphorylation in Vascular Smooth Muscle Cells

    Article • ACS Pharmacology & Translational Science, March 2020, American Chemical Society (ACS)

    Danielle Kamato

  26. The Role of Toll-like Receptors in Atherothrombotic Cardiovascular Disease

    Article • ACS Pharmacology & Translational Science, February 2020, American Chemical Society (ACS)

    Danielle Kamato

  27. ROS directly activates transforming growth factor β type 1 receptor signalling in human vascular smooth muscle cells

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, January 2020, Elsevier

    Danielle Kamato

  28. Lysophosphatidic acid and its receptors: pharmacology and therapeutic potential in atherosclerosis and vascular disease

    Article • Pharmacology & Therapeutics, December 2019, Elsevier

    Danielle Kamato

  29. GPCR transactivation signalling in vascular smooth muscle cells: role of NADPH oxidases and reactive oxygen species

    Article • Vascular Biology, August 2019, Bioscientifica

    Danielle Kamato

  30. Smad linker region phosphorylation is a signalling pathway in its own right and not only a modulator of canonical TGF-β signalling

    Article • Cellular and Molecular Life Sciences, August 2019, Springer Science + Business Media

    Danielle Kamato

  31. Mechanisms of PAR-1 mediated kinase receptor transactivation: Smad linker region phosphorylation

    Article • Journal of Cell Communication and Signaling, July 2019, Springer Science + Business Media

    Danielle Kamato

  32. Treatment of atherosclerotic plaque: perspectives on theranostics

    Article • Journal of Pharmacy and Pharmacology, April 2019, Wiley

    Danielle Kamato

  33. Individual Smad2 linker region phosphorylation sites determine the expression of proteoglycan and glycosaminoglycan synthesizing genes

    Article • Cellular Signalling, January 2019, Elsevier

    Danielle Kamato

  34. Endothelial function and dysfunction: Impact of metformin

    Article • Pharmacology & Therapeutics, December 2018, Elsevier

    Mrs Susan G Gray, Danielle Kamato

  35. Transforming growth factor–β1 mediated CHST11 and CHSY1 mRNA expression is ROS dependent in vascular smooth muscle cells

    Article • Journal of Cell Communication and Signaling, November 2018, Springer Science + Business Media

    Danielle Kamato

  36. Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics

    Article • Pharmacology & Therapeutics, November 2018, Elsevier

    Danielle Kamato

  37. Thrombin promotes PAI-1 expression and migration in keratinocytes via ERK dependent Smad linker region phosphorylation

    Article • Cellular Signalling, July 2018, Elsevier

    Danielle Kamato

  38. Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis

    Article • Pharmacology & Therapeutics, July 2018, Elsevier

    Danielle Kamato

  39. G protein coupled receptors can transduce signals through carboxy terminal and linker region phosphorylation of Smad transcription factors

    Article • Life Sciences, April 2018, Elsevier

    Danielle Kamato

  40. Flavopiridol Inhibits TGF-β-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2

    Article • Journal of Pharmacology and Experimental Therapeutics, February 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Danielle Kamato

  41. Activatable magnetic resonance nanosensor as a potential imaging agent for detecting and discriminating thrombosis

    Article • Nanoscale, January 2018, Royal Society of Chemistry

    Danielle Kamato

  42. RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells

    Article • PLOS One, July 2017, PLOS

    Danielle Kamato

  43. Animal models for assessing the impact of natural products on the aetiology and metabolic pathophysiology of Type 2 diabetes

    Article • Biomedicine & Pharmacotherapy, May 2017, Elsevier

    Mrs Susan G Gray, Danielle Kamato

  44. Insights into cellular signalling by G protein coupled receptor transactivation of cell surface protein kinase receptors

    Article • Journal of Cell Communication and Signaling, February 2017, Springer Science + Business Media

    Danielle Kamato

  45. Endothelin-1 (ET-1) stimulates carboxy terminal Smad2 phosphorylation in vascular endothelial cells by a mechanism dependent on ET receptors andde novoprotein synthesis

    Article • Journal of Pharmacy and Pharmacology, December 2016, Wiley

    Danielle Kamato

  46. Gaq proteins: molecular pharmacology and therapeutic potential

    Article • Cellular and Molecular Life Sciences, November 2016, Springer Science + Business Media

    Danielle Kamato

  47. The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle

    Article • Cellular Signalling, August 2016, Elsevier

    Danielle Kamato

  48. Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response

    Article • Journal of Pharmacy and Pharmacology, February 2016, Wiley

    Danielle Kamato

  49. Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling

    Article • British Journal of Pharmacology, February 2016, Wiley

    Danielle Kamato

  50. Multiple Growth Factors, But Not VEGF, Stimulate Glycosaminoglycan Hyperelongation in Retinal Choroidal Endothelial Cells

    Article • International Journal of Biological Sciences, January 2016, Ivyspring International Publisher

    Danielle Kamato

  51. Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes

    Article • Cellular Signalling, January 2016, Elsevier

    Danielle Kamato

  52. Structure, Function, Pharmacology, and Therapeutic Potential of the G Protein, Gα/q,11

    Article • Frontiers in Cardiovascular Medicine, March 2015, Frontiers

    Danielle Kamato

  53. Peptidyl-prolyl isomerases: Functionality and potential therapeutic targets in cardiovascular disease

    Article • Clinical and Experimental Pharmacology and Physiology, January 2015, Wiley

    Danielle Kamato

  54. The expansion of GPCR transactivation-dependent signalling to include serine/threonine kinase receptors represents a new cell signalling frontier

    Article • Cellular and Molecular Life Sciences, November 2014, Springer Science + Business Media

    Danielle Kamato

  55. 25Years of endothelin research: the next generation

    Article • Life Sciences, November 2014, Elsevier

    Dr Nicolas Vignon-Zellweger, Danielle Kamato

  56. Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells

    Article • Journal of Pharmacy and Pharmacology, October 2014, Wiley

    Danielle Kamato

  57. Assessing the Role of Gαq/11 in Cellular Responses: An Analysis of Investigative Tools

    Article • Clinical and Experimental Pharmacology, January 2014, OMICS Publishing Group

    Danielle Kamato

  58. Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle

    Article • Cardiovascular Diabetology, January 2014, Springer Science + Business Media

    Danielle Kamato

  59. Assessing the Role of Gαq/11 in Cellular Responses: An Analysis of Investigative Tools

    Article • Clinical and Experimental Pharmacology, January 2014, OMICS Publishing Group

    Danielle Kamato

  60. Transforming growth factor-β signalling: Role and consequences of Smad linker region phosphorylation

    Article • Cellular Signalling, October 2013, Elsevier

    Dr Suowen Xu, Danielle Kamato

  61. Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells

    Article • Journal of Pharmacy and Pharmacology, April 2013, Wiley

    Danielle Kamato

  62. (S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells

    Article • Journal of Pharmacy and Pharmacology, March 2013, Wiley

    Danielle Kamato

  63. Therapeutic implications of endothelin and thrombin G-protein-coupled receptor transactivation of tyrosine and serine/threonine kinase cell surface receptors

    Article • Journal of Pharmacy and Pharmacology, August 2012, Wiley

    Danielle Kamato

  64. Cell biology of Smad2/3 linker region phosphorylation in vascular smooth muscle

    Article • Clinical and Experimental Pharmacology and Physiology, July 2012, Wiley

    Danielle Kamato