All Stories

  1. Type IV pili facilitated natural competence in Fusobacterium nucleatum

    Article • Anaerobe, July 2023, Elsevier

    Dr. Daniel J Slade

  2. Type 4 pili mediated natural competence inFusobacterium nucleatum

    Article • June 2023, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  3. Enhanced Fusobacterium nucleatum Genetics Using Host DNA Methyltransferases To Bypass Restriction-Modification Systems

    Article • Journal of Bacteriology, November 2022, ASM Journals

    Dr. Daniel J Slade

  4. Fusobacterium nucleatum induces proliferation and migration in pancreatic cancer cells through host autocrine and paracrine signaling

    Article • Science Signaling, October 2022, American Association for the Advancement of Science

    Dr. Daniel J Slade

  5. DNA methyltransferase enhanced Fusobacterium nucleatum genetics

    Article • July 2022, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  6. The Shigella Spp. Type III Effector Protein OspB Is a Cysteine Protease

    Article • mBio, May 2022, ASM Journals

    Dr. Daniel J Slade

  7. CRISPR-Cas systems in Fusobacterium: An untapped genetic frontier

    Article • January 2022, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  8. Fusobacterium nucleatum infection induces pancreatic cancer cell proliferation and migration through regulation of host cytokine signaling

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  9. A Shigella type 3 effector protein co-opts host inositol pyrophosphates for activity

    Article • September 2021, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  10. Genome Sequences for Two Acinetobacter baumannii Strains Obtained Using the Unicycler Hybrid Assembly Pipeline

    Article • Microbiology Resource Announcements, March 2021, ASM Journals

    Dr. Daniel J Slade

  11. New Roles for Fusobacterium nucleatum in Cancer: Target the Bacteria, Host, or Both?

    Article • Trends in Cancer, December 2020, Elsevier

    Dr. Daniel J Slade

  12. Harnessing Tissue Engineering Tools to Interrogate Host-Microbiota Crosstalk in Cancer

    Article • iScience, November 2020, Elsevier

    Dr. Daniel J Slade

  13. Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration

    Article • Science Signaling, July 2020, American Association for the Advancement of Science

    Dr. Daniel J Slade

  14. The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View

    Article • Trends in Cancer, March 2020, Elsevier

    Dr. Daniel J Slade

  15. Comparison of type 5d autotransporter phospholipases demonstrates a correlation between high activity and intracellular pathogenic lifestyle

    Article • Biochemical Journal, September 2019, Portland Press Ltd.

    Dr. Daniel J Slade

  16. Utilizing Whole Fusobacterium Genomes To Identify, Correct, and Characterize Potential Virulence Protein Families

    Article • Journal of Bacteriology, September 2019, ASM Journals

    Dr. Daniel J Slade

  17. Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2

    Article • Biochemistry, June 2019, American Chemical Society (ACS)

    Dr. Daniel J Slade

  18. Complete Genome Sequence of Fusobacterium necrophorum subsp. necrophorum ATCC 25286

    Article • Microbiology Resource Announcements, February 2019, ASM Journals

    Dr. Daniel J Slade

  19. Reevaluating the Fusobacterium Virulence Factor Landscape

    Article • January 2019, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  20. Erratum for Sanders et al., “FusoPortal: an Interactive Repository of Hybrid MinION-Sequenced Fusobacterium Genomes Improves Gene Identification and Characterization”

    Article • mSphere, July 2018, ASM Journals

    Dr. Daniel J Slade

  21. FusoPortal: an Interactive Repository of Hybrid MinION-SequencedFusobacteriumGenomes Improves Gene Identification and Characterization

    Article • mSphere, July 2018, ASM Journals

    Dr. Daniel J Slade

  22. FusobacteriumGenomics Using MinION and Illumina Sequencing Enables Genome Completion and Correction

    Article • mSphere, July 2018, ASM Journals

    Dr. Daniel J Slade

  23. FusoPortal: An interactive repository of hybrid MinION sequenced Fusobacterium genomes improves gene identification and characterization

    Article • April 2018, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  24. Fusobacterium genomics using MinION and Illumina sequencing enables genome completion and correction

    Article • April 2018, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  25. Biological Studies and Target Engagement of the 2-C-Methyl-d-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1R,3S)-MMV008138 and Analogs

    Article • ACS Infectious Diseases, November 2017, American Chemical Society (ACS)

    Dr. Daniel J Slade

  26. A chemical and biological toolbox for Type Vd secretion: Characterization of the phospholipase A1 autotransporter FplA from Fusobacterium nucleatum

    Article • Journal of Biological Chemistry, October 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Daniel J Slade

  27. N-(3-oxododecanoyl)-L-homoserine lactone interactions in the breast tumor microenvironment: Implications for breast cancer viability and proliferation in vitro

    Article • PLoS ONE, July 2017, PLOS

    Dr. Daniel J Slade

  28. FplA From Fusobacterium nucleatum Is A Type Vd Autotransporter Phospholipase With A Proposed Role In Altered Host Signaling And Evasion Of Autophagy

    Article • May 2017, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  29. N-(3-Oxododecanoyl)-L-Homoserine Lactone Interactions In The Breast Tumor Microenvironment: Implications For Breast Cancer Viability And Proliferation In Vitro

    Article • April 2017, Cold Spring Harbor Laboratory Press

    Dr. Daniel J Slade

  30. Enhanced Mucosal Defense and Reduced Tumor Burden in Mice with the Compromised Negative Regulator IRAK-M

    Article • EBioMedicine, December 2016, Elsevier

    Dr. Daniel J Slade

  31. Chemical Proteomic Platform To Identify Citrullinated Proteins

    Article • ACS Chemical Biology, November 2015, American Chemical Society (ACS)

    Dr. Daniel J Slade

  32. Protein Arginine Deiminase 2 Binds Calcium in an Ordered Fashion: Implications for Inhibitor Design

    Article • ACS Chemical Biology, April 2015, American Chemical Society (ACS)

    Dr. Daniel J Slade

  33. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

    Article • Nature Chemical Biology, January 2015, Springer Science + Business Media

    Dr Rab K Prinjha, Dr. Daniel J Slade

  34. A novel role for protein arginine deiminase 4 in pluripotency: The emerging role of citrullinated histone H1 in cellular programming

    Article • BioEssays, May 2014, Wiley

    Dr. Daniel J Slade

  35. Pluripotency: Citrullination unravels stem cells

    Article • Nature Methods, April 2014, Nature

    Dr. Daniel J Slade

  36. Chemical and biological methods to detect post-translational modifications of arginine

    Article • Biopolymers, November 2013, Wiley

    Dr. Daniel J Slade

  37. Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation

    Article • Proceedings of the National Academy of Sciences, August 2012, Proceedings of the National Academy of Sciences

    Dr. Daniel J Slade

  38. Genetic Reporter System for Positioning of Proteins at the Bacterial Pole

    Article • mBio, February 2012, ASM Journals

    Dr. Daniel J Slade

  39. Activation of PAD4 in NET formation

    Article • Frontiers in Immunology, January 2012, Frontiers

    Dr. Daniel J Slade

  40. Crystal Structure of the MACPF Domain of Human Complement Protein C8α in Complex with the C8γ Subunit

    Article • Journal of Molecular Biology, May 2008, Elsevier

    Dr. Daniel J Slade, Dr Wladek Minor

  41. Crystal structure of complement protein C8γ in complex with a peptide containing the C8γ binding site on C8α: Implications for C8γ ligand binding

    Article • Molecular Immunology, February 2008, Elsevier

    Dr. Daniel J Slade

  42. Binding of the lipocalin C8γ to human complement protein C8α is mediated by loops located at the entrance to the C8γ ligand binding site

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, September 2006, Elsevier

    Dr. Daniel J Slade

  43. Functional Studies of the MACPF Domain of Human Complement Protein C8α Reveal Sites for Simultaneous Binding of C8β, C8γ, and C9 †

    Article • Biochemistry, April 2006, American Chemical Society (ACS)

    Dr. Daniel J Slade