All Stories

  1. Why AMPK agonists not known to be stressors may surprisingly contribute to miscarriage or hinder IVF/ART

    Article • Journal of Assisted Reproduction and Genetics, June 2018, Springer Science + Business Media

    Daniel Rappolee

  2. AMPK agonist drugs and diets supplements cause more harm to 2-cell embryos than blastocysts

    Article • Birth Defects Research, October 2017, Wiley

    Daniel Rappolee

  3. Hypoxic Stress Forces Irreversible Differentiation of a Majority of Mouse Trophoblast Stem Cells Despite FGF4

    Article • Biology of Reproduction, September 2016, Oxford University Press (OUP)

    Daniel Rappolee, Nardhy Gomez-Lopez

  4. A quiet death; hypoxic stress forces diminished growth and potency and large, irreversible trophoblast stem cell differentiation

    Article • Placenta, September 2016, Elsevier

    Daniel Rappolee

  5. Comparison of 2, 5, and 20 % O2 on the development of post-thaw human embryos

    Article • Journal of Assisted Reproduction and Genetics, March 2016, Springer Science + Business Media

    Daniel Rappolee

  6. Molecular Biology of the Stress Response in the Early Embryo and its Stem Cells

    Article • January 2015, Springer Science + Business Media

    Daniel Rappolee

  7. Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency

    Article • Stem Cell Research, November 2014, Elsevier

    Daniel Rappolee

  8. When Stresses Collide1

    Article • Biology of Reproduction, September 2013, Oxford University Press (OUP)

    Daniel Rappolee

  9. Development of the placental surface requires stress response genes

    Article • March 2013, Bioscientifica

    Daniel Rappolee

  10. Adaptive and Pathogenic Responses to Stress by Stem Cells during Development

    Article • Cells, December 2012, MDPI AG

    Daniel Rappolee

  11. Oxygen levels that optimize TSC culture are identified by maximizing growth rates and minimizing stress

    Article • Placenta, June 2011, Elsevier

    Daniel Rappolee

  12. The Phosphoinositide Kinase PIKfyve Is Vital in Early Embryonic Development

    Article • Journal of Biological Chemistry, February 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Daniel Rappolee

  13. Interpreting the Stress Response of Early Mammalian Embryos and Their Stem Cells

    Article • January 2011, Elsevier

    Daniel Rappolee

  14. Cellular stress causes reversible, PRKAA1/2-, and proteasome-dependent ID2 protein loss in trophoblast stem cells

    Article • Reproduction, December 2010, Bioscientifica

    Daniel Rappolee

  15. Benzopyrene and Experimental Stressors Cause Compensatory Differentiation in Placental Trophoblast Stem Cells

    Article • Systems Biology in Reproductive Medicine, January 2010, Taylor & Francis

    Daniel Rappolee

  16. Hyperosmolar Stress Induces Global mRNA Responses in Placental Trophoblast Stem Cells that Emulate Early Post-implantation Differentiation

    Article • Placenta, January 2009, Elsevier

    Daniel Rappolee

  17. Using hyperosmolar stress to measure biologic and stress-activated protein kinase responses in preimplantation embryos

    Article • Molecular Human Reproduction, May 2007, Oxford University Press (OUP)

    Daniel Rappolee

  18. Impact of transient stress and stress enzymes on development

    Article • Developmental Biology, April 2007, Elsevier

    Daniel Rappolee

  19. Pipetting causes shear stress and elevation of phosphorylated stress-activated protein kinase/jun kinase in preimplantation embryos

    Article • Molecular Reproduction and Development, January 2007, Wiley

    Daniel Rappolee

  20. Increases in phosphorylation of SAPK/JNK and p38MAPK correlate negatively with mouse embryo development after culture in different media

    Article • Fertility and Sterility, April 2005, Elsevier

    Daniel Rappolee

  21. Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos

    Article • Developmental Dynamics, January 2004, Wiley

    Daniel Rappolee

  22. FGF Is an Essential Regulator of the Fifth Cell Division in Preimplantation Mouse Embryos

    Article • Developmental Biology, June 1998, Elsevier

    Daniel Rappolee

  23. Expression of SRY transcripts in preimplantation human embryos

    Article • American Journal of Medical Genetics, January 1995, Wiley

    Daniel Rappolee

  24. Novel method for studying mRNA phenotypes in single or small numbers of cells

    Article • Journal of Cellular Biochemistry, January 1989, Wiley

    Daniel Rappolee

  25. Wound macrophages express TGF-alpha and other growth factors in vivo: analysis by mRNA phenotyping

    Article • Science, August 1988, American Association for the Advancement of Science

    Daniel Rappolee