All Stories

  1. ΔFlucs: Brighter Photinus pyralis firefly luciferases identified by surveying consecutive single amino acid deletion mutations in a thermostable variant

    Article • Biotechnology and Bioengineering, October 2017, Wiley

    Dr Dafydd Jones

  2. Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position.

    Article • July 2016, Protein Data Bank, Rutgers University

    Dr Dafydd Jones

  3. Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position.

    Article • July 2016, Protein Data Bank, Rutgers University

    Dr Dafydd Jones

  4. Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle

    Article • Chemical Science, January 2016, Royal Society of Chemistry

    Dr Dafydd Jones

  5. Correction: Functional modulation and directed assembly of an enzyme through designed non-natural post-translation modification

    Article • Chemical Science, January 2016, Royal Society of Chemistry

    Dr Dafydd Jones

  6. Irradiated state of mCherry143azF

    Article • September 2015, Protein Data Bank, Rutgers University

    Dr Dafydd Jones

  7. Genetically encoded Phenyl Azide Photochemistry Drive Positive and Negative Functional Modulation of a Red Fluorescent Protein

    Article • September 2015, Protein Data Bank, Rutgers University

    Dr Dafydd Jones

  8. In-Frame Amber Stop Codon Replacement Mutagenesis for the Directed Evolution of Proteins Containing Non-Canonical Amino Acids: Identification of Residues Open to Bio-Orthogonal Modification

    Article • PLoS ONE, May 2015, PLOS

    Dr Dafydd Jones

  9. Cloning, expression and in silico studies of a serine protease from a marine actinomycete (Nocardiopsis sp. NCIM 5124)

    Article • Process Biochemistry, March 2015, Elsevier

    Dr Dafydd Jones

  10. Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescence

    Article • Chemical Science, January 2015, Royal Society of Chemistry

    Dr Dafydd Jones

  11. Functional modulation and directed assembly of an enzyme through designed non-natural post-translation modification

    Article • Chemical Science, January 2015, Royal Society of Chemistry

    Dr Dafydd Jones

  12. Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Dafydd Jones

  13. Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein

    Article • Acta Crystallographica Section D Biological Crystallography, July 2014, International Union of Crystallography

    Dr Pierre J Rizkallah, Dr Dafydd Jones

  14. Random Single Amino Acid Deletion Sampling Unveils Structural Tolerance and the Benefits of Helical Registry Shift on GFP Folding and Structure

    Article • Structure, June 2014, Elsevier

    Dr Dafydd Jones

  15. Transposon-Based Approaches for Generating Novel Molecular Diversity During Directed Evolution

    Article • January 2014, Springer Science + Business Media

    Dr Dafydd Jones

  16. Genetically encoding phenyl azide chemistry: new uses and ideas for classical biochemistry

    Article • Biochemical Society Transactions, October 2013, Portland Press Ltd.

    Dr Dafydd Jones

  17. Different photochemical events of a genetically encoded aryl azide define and modulate GFP fluorescence

    Article • June 2013, Protein Data Bank, Rutgers University

    Dr Dafydd Jones

  18. Dark-state structure of sfGFP containing the unnatural amino acid p-azido-phenylalanine at residue 66

    Article • June 2013, Protein Data Bank, Rutgers University

    Dr Dafydd Jones

  19. Irradiated-state structure of sfGFP containing the unnatural amino acid p-azido-phenylalanine at residue 145

    Article • May 2013, Protein Data Bank, Rutgers University

    Dr Dafydd Jones

  20. Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence

    Article • Angewandte Chemie, April 2013, Wiley

    Dr Dafydd Jones

  21. Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence

    Article • Angewandte Chemie International Edition, April 2013, Wiley

    Dr Dafydd Jones

  22. Aryl Azide Photochemistry in Defined Protein Environments

    Article • Organic Letters, February 2013, American Chemical Society (ACS)

    Dr Dafydd Jones

  23. Crystal Structure of Enhanced Green Fluorescent Protein to 1.35 Å Resolution Reveals Alternative Conformations for Glu222

    Article • PLoS ONE, October 2012, PLOS

    Dr Dafydd Jones

  24. Structural Basis for Efficient Chromophore Communication and Energy Transfer in a Constructed Didomain Protein Scaffold

    Article • Journal of the American Chemical Society, August 2012, American Chemical Society (ACS)

    Dr Dafydd Jones

  25. Direct Binding of a Redox Protein for Single-Molecule Electron Transfer Measurements

    Article • Small, May 2012, Wiley

    Dr Dafydd Jones

  26. Orientation-Dependent Electron Transport in a Single Redox Protein

    Article • ACS Nano, January 2012, American Chemical Society (ACS)

    Dr Dafydd Jones

  27. Residue choice defines efficiency and influence of bioorthogonal protein modification via genetically encoded strain promoted Click chemistry

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Dr Dafydd Jones

  28. Redox tuning of cytochrome b562 through facile metal porphyrin substitution

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Professor Qijin Chi, Dr Dafydd Jones

  29. Fast electron transfer through a single molecule natively structured redox protein

    Article • Nanoscale, January 2012, Royal Society of Chemistry

    Professor Qijin Chi, Dr Dafydd Jones

  30. The role of substrate specificity and metal binding in defining the activity and structure of an intracellular subtilisin

    Article • FEBS Open Bio, January 2012, Wiley

    Dr Dafydd Jones

  31. Recombining Low Homology, Functionally Rich Regions of Bacterial Subtilisins by Combinatorial Fragment Exchange

    Article • PLoS ONE, September 2011, PLOS

    Dr Dafydd Jones

  32. Single-Molecule Mapping of Long-range Electron Transport for a Cytochrome b562 Variant

    Article • Nano Letters, November 2010, American Chemical Society (ACS)

    Professor Qijin Chi, Dr Dafydd Jones

  33. Regulation of β-Lactamase Activity by Remote Binding of Heme: Functional Coupling of Unrelated Proteins through Domain Insertion

    Article • Biochemistry, August 2010, American Chemical Society (ACS)

    Dr Dafydd Jones

  34. Crystal Structure of an Intracellular Subtilisin Reveals Novel Structural Features Unique to this Subtilisin Family

    Article • Structure, June 2010, Elsevier

    Dr Dafydd Jones

  35. A Surface Loop Directs Conformational Switching of a Lipoyl Domain Between a Folded and a Novel Misfolded Structure

    Article • Structure, August 2009, Elsevier

    Dr Dafydd Jones

  36. Expanded chemical diversity sampling through whole protein evolution

    Article • Molecular BioSystems, January 2009, Royal Society of Chemistry

    Dr Dafydd Jones

  37. Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx)

    Article • Nucleic Acids Research, June 2008, Oxford University Press (OUP)

    Dr Dafydd Jones

  38. Linking the functions of unrelated proteins using a novel directed evolution domain insertion method

    Article • Nucleic Acids Research, June 2008, Oxford University Press (OUP)

    Dr Dafydd Jones

  39. Allosteric Activation of HtrA Protease DegP by Stress Signals during Bacterial Protein Quality Control

    Article • Angewandte Chemie International Edition, February 2008, Wiley

    Dr Dafydd Jones

  40. Allosterische Aktivierung der HtrA-Protease DegP durch Stress-Signale während der bakteriellen Proteinqualitätskontrolle

    Article • Angewandte Chemie, February 2008, Wiley

    Dr Dafydd Jones

  41. The role of loop and β-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex

    Article • Biochemical Journal, January 2008, Portland Press Ltd.

    Dr Dafydd Jones

  42. Investigating protein structural plasticity by surveying the consequence of an amino acid deletion from TEM-1 β-lactamase

    Article • FEBS Letters, July 2007, Wiley

    Dr Dafydd Jones

  43. Controlling Self-Assembly by Linking Protein Folding, DNA Binding, and the Redox Chemistry of Heme

    Article • Angewandte Chemie, October 2005, Wiley

    Dr Dafydd Jones

  44. Controlling Self-Assembly by Linking Protein Folding, DNA Binding, and the Redox Chemistry of Heme

    Article • Angewandte Chemie International Edition, October 2005, Wiley

    Dr Dafydd Jones

  45. Design and Characterisation of an Artificial DNA-Binding Cytochrome

    Article • ChemBioChem, July 2004, Wiley

    Dr Dafydd Jones

  46. Substrate channelling in 2-oxo acid dehydrogenase multienzyme complexes

    Article • Biochemical Society Transactions, April 2002, Portland Press Ltd.

    Dr Dafydd Jones

  47. Substrate channelling in 2-oxo acid dehydrogenase multienzyme complexes

    Article • Biochemical Society Transactions, April 2001, Portland Press Ltd.

    Dr Dafydd Jones

  48. Restricted Motion of the Lipoyl-Lysine Swinging Arm in the Pyruvate Dehydrogenase Complex of Escherichia coli † , ‡

    Article • Biochemistry, July 2000, American Chemical Society (ACS)

    Dr Dafydd Jones

  49. INNERMOST LIPOYL DOMAIN OF THE PYRUVATE DEHYDROGENASE FROM ESCHERICHIA COLI

    Article • June 1999, Protein Data Bank, Rutgers University

    Dr Dafydd Jones