All Stories

  1. Remarkable Solvent Effects of Structurally Diverse Alcohols on Nucleophilic Displacement Reactions with Halide Ions
  2. Early Detection of Aβ Deposition in the 5xFAD Mouse by Amyloid PET
  3. AETIQ: A Novel Synthetic Compound with Anti-inflammatory Properties in Activated Microglia
  4. Genetic incorporation of unnatural amino acids biosynthesized from α-keto acids by an aminotransferase
  5. Organocatalysis of nucleophilic substitution reactions by the combined effects of two promoters fused in a molecule: oligoethylene glycol substituted imidazolium salts
  6. High Efficiency Synthesis of F-18 Fluoromethyl Ethers: An Attractive Alternative for C-11 Methyl Groups in Positron Emission Tomography Radiopharmaceuticals
  7. ChemInform Abstract: Approach to the Synthesis of Indoline Derivatives from Diaryliodonium Salts.
  8. Approach to the Synthesis of Indoline Derivatives from Diaryliodonium Salts
  9. ChemInform Abstract: The Use of Sodium Chlorate/Hydrochloric Acid Mixtures as a Novel and Selective Chlorination Agent.
  10. New automated synthesis of [18F]FP-CIT with base amount control affording high and stable radiochemical yield: a 1.5-year production report
  11. An efficient synthesis of ([18F]fluoropropyl)quinoline-5,8-diones by rapid radiofluorination–oxidative demethylation
  12. ChemInform Abstract: Azide/Alkyne Resins for Quick Preparation of 1,4‐Disubstituted 1,2,3‐Triazoles.
  13. ChemInform Abstract: Copper Nitride Nanoparticles Supported on a Superparamagnetic Mesoporous Microsphere for Toxic‐Free Click Chemistry.
  14. ChemInform Abstract: Facile Ring‐Closure Cyclization of Arenes by Nucleophilic C‐Alkylation Reaction in Ionic Liquid.
  15. ChemInform Abstract: tert‐Alcohol‐Functionalized Imidazolium Ionic Liquid: Catalyst for Mild Nucleophilic Substitution Reactions at Room Temperature.
  16. Facile ring-closure cyclization of arenes by nucleophilic C-alkylation reaction in ionic liquid
  17. tert-Alcohol-functionalized imidazolium ionic liquid: catalyst for mild nucleophilic substitution reactions at room temperature
  18. Bis‐Terminal Hydroxy Polyethers as All‐Purpose, Multifunctional Organic Promoters: A Mechanistic Investigation and Applications
  19. Bis‐Terminal Hydroxy Polyethers as All‐Purpose, Multifunctional Organic Promoters: A Mechanistic Investigation and Applications
  20. ChemInform Abstract: Synthesis of 9‐Anthryl Ethers from trans‐9,10‐Dihydro‐9,10‐dimethoxyanthracene by Acid‐Catalyzed Transetherification.
  21. A Mechanistic Study of SN2 Reaction in a Diol Solvent
  22. ChemInform Abstract: Ionic Polymer‐Supported Copper(I): A Reusable Catalyst for Huisgen′s 1,3‐Dipolar Cycloaddition.
  23. ChemInform Abstract: Syntheses of Tetrahydroisoquinoline Derivatives that Inhibit NO Production in Activated BV‐2 Microglial Cells.
  24. ChemInform Abstract: Facile Nucleophilic Fluorination by Synergistic Effect Between Polymer‐Supported Ionic Liquid Catalyst and tert‐Alcohol Reaction Media System.
  25. Electrophilic aromatic addition reaction (AdEAr) to anthracene
  26. Polymer-supported protic functionalized ionic liquids for nucleophilic substitution reactions: superior catalytic activity compared to other ionic resins
  27. Synergistic Effect of Two Solvents, tert-Alcohol and Ionic Liquid, in One Molecule in Nucleophilic Fluorination
  28. Comparison of synthesis yields of 3′‐deoxy‐3′‐[18F]fluorothymidine by nucleophilic fluorination in various alcohol solvents
  29. Convenient One-Pot Synthesis of 2,2-Bis-(4-hydroxyphenyl)-cyclopentanone
  30. Synthesis of novel phytosphingosine derivatives and their preliminary biological evaluation for enhancing radiation therapy
  31. Short Commmunication: Synthesis and Biologic Evaluation of I-123-Labeled Porphyrin Derivative as a Potential Tumor-Imaging Agent
  32. Facile SN2 Reaction in Protic Solvent:  Quantum Chemical Analysis
  33. Strapped-calix[4]pyrroles Bearing Acridine Moiety
  34. The automatic production of 16α-[18F]fluoroestradiol using a conventional [18F]FDG module with a disposable cassette system
  35. An efficient F-18 labeling method for PET study: Huisgen 1,3-dipolar cycloaddition of bioactive substances and F-18-labeled compounds
  36. 99mTc(CO)3-15-[N-(Acetyloxy)-2-picolylamino]pentadecanoic Acid:  A Potential Radiotracer for Evaluation of Fatty Acid Metabolism
  37. One-step high-radiochemical-yield synthesis of [18F]FP-CIT using a protic solvent system
  38. Simple and highly efficient synthesis of 3′-deoxy-3′-[18F]fluorothymidine using nucleophilic fluorination catalyzed by protic solvent
  39. Oxidation of Aromatic Aldehydes with Tetrabutylammonium Fluoride: Competition with the Cannizzaro Reaction.
  40. Structural Modification of Polymer‐Supported Ionic Liquids as Catalysts for Nucleophilic Substitution Reactions Including Fluorination
  41. Ionic Liquids: An Environmentally Friendly Media for Nucleophilic Substitution Reactions
  42. Potassium Carbonate as a Base for the N‐Alkylation of Indole and Pyrrole in Ionic Liquids.
  43. Acetonitrile‐Mediated Synthesis of 2,4‐Dichloroquinoline from 2‐Ethynylanilines and 2,4‐Dichloroquinazoline from Anthranilonitrile.
  44. Potassium carbonate as a base for the N-alkylation of indole and pyrrole in ionic liquids
  45. Synthesis of Symmetrical Organic Carbonates via Significantly Enhanced Alkylation of Metal Carbonates with Alkyl Halides/Sulfonates in Ionic Liquid.
  46. Preparation of 3′‐deoxy‐3′‐[18F]fluorothymidine ([18F]FLT) in ionic liquid, [bmim][OTf]
  47. Acetonitrile-Mediated Synthesis of 2,4-Dichloroquinoline from 2-Ethynyl­aniline and 2,4-Dichloroquinazoline from Anthranilonitrile
  48. Synthesis of Symmetrical Organic Carbonates via Significantly Enhanced Alkylation of Metal Carbonates with Alkyl Halides/Sulfonates in Ionic Liquid
  49. Fully automated synthesis of [18F]fluoromisonidazole using a conventional [18F]FDG module
  50. Aromatic Fluorination by Decomposition of Triazenes in Ionic Liquids.
  51. Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 4: 3-Alkyl-4-halo-6-nitroquipazines
  52. Efficient methods for the synthesis of 5‐(4‐[18F]fluorophenyl)‐10,15,20‐tris(3‐methoxyphenyl)porphyrin as a potential imaging agent for tumor
  53. Mono‐ and Dialkylations of Pyrrole at C2 and C5 Positions by Nucleophilic Substitution Reaction in Ionic Liquid.
  54. Electrophilic Aromatic Addition Reaction: Electrophilic Attack at an Aromatic H Substituent Position.
  55. Mono- and Dialkylations of Pyrrole at C2 and C5 Positions by Nucleophilic Substitution Reaction in Ionic Liquid
  56. Electrophilic Aromatic Addition Reaction:  Electrophilic Attack at an Aromatic H Substituent Position
  57. Synthesis and evaluation of fluorine-substituted 1H-pyrrolo[2,3-b]pyridine derivatives for dopamine D4 receptor imaging
  58. The Syntheses of 3‐Substituted 4‐(Pyridin‐2‐ylthio)indoles via Leimgruber—Batcho Indole Synthesis.
  59. Simple Preparation of 7‐Alkylamino‐2‐methylquinoline‐5,8‐diones: Regiochemistry in Nucleophilic Substitution Reactions of the 6‐ or 7‐Bromo‐2‐methylquinoline‐5,8‐dione with Amines.
  60. Application of Ionic Liquid Halide Nucleophilicity for the Cleavage of Ethers: A Green Protocol for the Regeneration of Phenols from Ethers.
  61. Hydroxylation of Alkyl Halides with Water in Ionic Liquid: Significantly Enhanced Nucleophilicity of Water.
  62. Fully automated synthesis system of 3′-deoxy-3′-[18F]fluorothymidine
  63. Polymer‐Supported Ionic Liquids: Imidazolium Salts as Catalysts for Nucleophilic Substitution Reactions Including Fluorinations.
  64. Syntheses and Radical Scavenging Activities of Resveratrol Derivatives.
  65. Hydroxylation of Alkyl Halides with Water in Ionic Liquid:  Significantly Enhanced Nucleophilicity of Water
  66. Polymer‐Supported Ionic Liquids: Imidazolium Salts as Catalysts for Nucleophilic Substitution Reactions Including Fluorinations
  67. Polymer‐Supported Ionic Liquids: Imidazolium Salts as Catalysts for Nucleophilic Substitution Reactions Including Fluorinations
  68. Syntheses and radical scavenging activities of resveratrol derivatives
  69. Formylchromone Derivatives as a Novel Class of Protein Tyrosine Phosphatase 1B Inhibitors.
  70. Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors
  71. Synthesis and binding affinities of fluoroalkylated raloxifenes
  72. Nonselective Bromination—Selective Debromination Strategy: Selective Bromination of Unsymmetrical Ketones on Singly Activated Carbon Against Doubly Activated Carbon.
  73. Significantly Enhanced Reactivities of the Nucleophilic Substitution Reactions in Ionic Liquid
  74. Novel one-pot one-step synthesis of 2′-[18F]fluoroflumazenil (FFMZ) for benzodiazepine receptor imaging
  75. Preparation of 7-Alkylamino-2-methylquinoline-5,8-diones.
  76. Osmium Tetroxide—(QN)2PHAL in an Ionic Liquid: A Highly Efficient and Recyclable Catalyst System for Asymmetric Dihydroxylation of Olefins.
  77. Novel Synthesis of 2‐Chloroquinolines from 2‐Vinylanilines in Nitrile Solvent.
  78. Preparation of 7‐Alkylamino‐2‐methylquinoline‐5,8‐diones.
  79. Nonselective Bromination−Selective Debromination Strategy:  Selective Bromination of Unsymmetrical Ketones on Singly Activated Carbon against Doubly Activated Carbon
  80. New Method of Fluorination Using Potassium Fluoride in Ionic Liquid: Significantly Enhanced Reactivity of Fluoride and Improved Selectivity.
  81. Novel Synthesis of 2-Chloroquinolines from 2-Vinylanilines in Nitrile Solvent
  82. Hydroacylation of 4‐[18F]fluorobenzaldehyde: a novel method for the preparation of 4′‐[18F]phenylketones
  83. New Method of Fluorination Using Potassium Fluoride in Ionic Liquid:  Significantly Enhanced Reactivity of Fluoride and Improved Selectivity
  84. Preparation of 7-Alkylamino-2-methylquinoline-5,8-diones
  85. ChemInform Abstract: Synthesis and SAR of Aziridinylquinoline‐5,8‐diones as Agents Against Malignant Tumor Cells.
  86. ChemInform Abstract: Bromodecarboxylation of Arylpropiolic Acids with Oxone® and Sodium Bromide.
  87. Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. part 2: 4-Substituted 6-nitroquipazines
  88. ChemInform Abstract: A Facile Debromination Reaction: Can Bromide Now Be Used as a Protective Group in Aromatic Systems?
  89. Synthesis and binding affinities of 2β-(3-iodoallyloxycarbonyl)-3β-(4-substituted-aryl)tropane analogues as ligands for the dopamine transporter studies
  90. A Facile Debromination Reaction:  Can Bromide Now Be Used as a Protective Group in Aromatic Systems?
  91. ChemInform Abstract: Facile Oxidation of Fused 1,4‐Dimethoxybenzenes to 1,4‐Quinones Using NBS: Fine‐Tuned Control over Bromination and Oxidation Reactions.
  92. ChemInform Abstract: The Regioselectivity in the Reaction of 6,7‐Dihaloquinoline‐5,8‐diones with Amine Nucleophiles in Various Solvents.
  93. ChemInform Abstract: Syntheses and Binding Affinities of 6‐Nitroquipazine Analogues for Serotonin Transporter. Part 1.
  94. The regioselectivity in the reaction of 6,7-dihaloquinoline-5,8-diones with amine nucleophiles in various solvents
  95. ChemInform Abstract: Heterogeneous Asymmetric Epoxidation of Alkenes Catalyzed by a Polymer‐Bound (Pyrrolidine salen)manganese(III) Complex.
  96. Synthesis and in vitro antibacterial activity of 3-[ N -methyl- N -(3-methyl-1,3-thiazolium-2-yl)amino]methyl cephalosporin derivatives
  97. ChemInform Abstract: Palladium‐Catalyzed Functionalization of 5‐ and 7‐Azaindoles.
  98. Palladium-catalyzed functionalization of 5- and 7-azaindoles
  99. ChemInform Abstract: Design and Synthesis of Binaphthol‐Derived Chiral Ketone Catalysts for Dioxirane‐Mediated Asymmetric Epoxidation of Olefins.
  100. Radiolabeling of paclitaxel with electrophilic 123 I
  101. An Efficient Synthesis of (Fluoromethyl)pyridylamines for Labeling with Fluorine-18
  102. ChemInform Abstract: Study on the Novel Rearrangement Reaction of Bicyclic Acetal Compounds by Using AcCl—NaI.
  103. ChemInform Abstract: A New Efficient Synthesis of 6‐Nitroquipazine.
  104. ChemInform Abstract: New Efficient Syntheses of 6,7‐Dibromoquinoline‐5,8‐diones.
  105. A New Efficient Synthesis of 6-Nitroquipazine
  106. New Efficient Syntheses of 6,7-Dibromoquinoline-5,8-diones
  107. Heterodimeric Bis(amino thiol) Complexes of Oxorhenium(V) That Mimic the Structure of Steroid Hormones. Synthesis and Stereochemical Issues
  108. Spin-Labeled Psoralen Probes for the Study of DNA Dynamics
  109. Selective formation of heterodimeric bis-bidentate aminothiol-oxometal complexes or rhenium(V)
  110. PHOTOCYCLOADDITION REACTION OF 5,7-DIMETHOXYCOUMARIN TO THYMIDINE
  111. PHOTOCYCLOADDITION REACTION OF 5,7-DIMETHOXYCOUMARIN TO THYMIDINE
  112. PHOTOCYCLOADDITION OF 5,7-DIMETHOXYCOUMARIN TO TETRAMETHYLETHYLENE