All Stories

  1. An intrinsically disordered proteins community for ELIXIR

    Article • F1000Research, October 2019, Faculty of 1000, Ltd.

    Cy Jeffries, Wim Vranken, Richard Edwards, Dr Vasilis J Promponas, Roberta Pierattelli, Dr John M Hancock

  2. Recombinant production of A1S_0222 from Acinetobacter baumannii ATCC 17978 and confirmation of its DNA-(adenine N6)-methyltransferase activity

    Article • Protein Expression and Purification, November 2018, Elsevier

    Cy Jeffries

  3. Machine Learning Methods for X-Ray Scattering Data Analysis from Biomacromolecular Solutions

    Article • Biophysical Journal, June 2018, Elsevier

    Cy Jeffries

  4. Consensus Bayesian assessment of protein molecular mass from solution X-ray scattering data

    Article • Scientific Reports, May 2018, Springer Science + Business Media

    Cy Jeffries

  5. Functional interaction of low-homology FRPs from different cyanobacteria with Synechocystis OCP

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, May 2018, Elsevier

    Cy Jeffries

  6. Influenza virus Matrix Protein M1 preserves its conformation with pH, changing multimerization state at the priming stage due to electrostatics

    Article • Scientific Reports, December 2017, Springer Science + Business Media

    Cy Jeffries

  7. Interactions between LHX3- and ISL1-family LIM-homeodomain transcription factors are conserved in Caenorhabditis elegans

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Cy Jeffries

  8. ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

    Article • Journal of Applied Crystallography, June 2017, International Union of Crystallography

    Cy Jeffries

  9. Sample and Buffer Preparation for SAXS

    Article • January 2017, Springer Science + Business Media

    Cy Jeffries

  10. Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments

    Article • Nature Protocols, October 2016, Springer Science + Business Media

    Cy Jeffries

  11. X-Ray Solution Scattering Study of Four Escherichia coli Enzymes Involved in Stationary-Phase Metabolism

    Article • PLoS ONE, May 2016, PLOS

    Cy Jeffries

  12. Expression, purification and crystallization of human kynurenine aminotransferase 2 exploiting a highly optimized codon set

    Article • Protein Expression and Purification, May 2016, Elsevier

    Cy Jeffries

  13. Domain-swap polymerization drives the self-assembly of the bacterial flagellar motor

    Article • Nature Structural & Molecular Biology, February 2016, Springer Science + Business Media

    Cy Jeffries

  14. Exploring the structure of biological macromolecules in solution using Quokka, the small angle neutron scattering instrument, at ANSTO

    Article • Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment, October 2015, Elsevier

    Cy Jeffries

  15. Cooperative folding of intrinsically disordered domains drives assembly of a strong elongated protein

    Article • Nature Communications, June 2015, Springer Science + Business Media

    Dr Fiona Whelan, Cy Jeffries

  16. Automated Pipeline for Purification, Biophysical and X-Ray Analysis of Biomacromolecular Solutions

    Article • Scientific Reports, June 2015, Springer Science + Business Media

    Cy Jeffries

  17. Correlation Map, a goodness-of-fit test for one-dimensional X-ray scattering spectra

    Article • Nature Methods, April 2015, Springer Science + Business Media

    Cy Jeffries

  18. Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY)

    Article • Journal of Applied Crystallography, March 2015, International Union of Crystallography

    Cy Jeffries

  19. Limiting radiation damage for high-brilliance biological solution scattering: practical experience at the EMBL P12 beamline PETRAIII

    Article • Journal of Synchrotron Radiation, February 2015, International Union of Crystallography

    Cy Jeffries

  20. High-Throughput Studies of Protein Shapes and Interactions by Synchrotron Small-Angle X-Ray Scattering

    Article • November 2014, Springer Science + Business Media

    Cy Jeffries

  21. SASBDB, a repository for biological small-angle scattering data

    Article • Nucleic Acids Research, October 2014, Oxford University Press (OUP)

    Cy Jeffries

  22. The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor

    Article • PLoS Pathogens, July 2014, PLOS

    Cy Jeffries

  23. Structural Analysis of Influenza A Virus Matrix Protein M1 and Its Self-Assemblies at Low pH

    Article • PLoS ONE, December 2013, PLOS

    Cy Jeffries

  24. K7del is a common TPM2 gene mutation associated with nemaline myopathy and raised myofibre calcium sensitivity

    Article • Brain, January 2013, Oxford University Press (OUP)

    Cy Jeffries

  25. Calmodulin Binds a Highly Extended HIV-1 MA Protein That Refolds Upon Its Release

    Article • Biophysical Journal, August 2012, Elsevier

    Cy Jeffries

  26. Solution Structure of the LIM-Homeodomain Transcription Factor Complex Lhx3/Ldb1 and the Effects of a Pituitary Mutation on Key Lhx3 Interactions

    Article • PLoS ONE, July 2012, PLOS

    Cy Jeffries

  27. The Motif of Human Cardiac Myosin-binding Protein C Is Required for Its Ca2+-dependent Interaction with Calmodulin

    Article • Journal of Biological Chemistry, July 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Cy Jeffries

  28. Solution structure studies of monomeric human TIP47/perilipin-3 reveal a highly extended conformation

    Article • Proteins Structure Function and Bioinformatics, January 2012, Wiley

    Cy Jeffries

  29. Human Cardiac Myosin Binding Protein C: Structural Flexibility within an Extended Modular Architecture

    Article • Journal of Molecular Biology, December 2011, Elsevier

    Cy Jeffries

  30. The C0C1 Fragment of Human Cardiac Myosin Binding Protein C Has Common Binding Determinants for Both Actin and Myosin

    Article • Journal of Molecular Biology, November 2011, Elsevier

    Cy Jeffries

  31. Structural Basis for Partial Redundancy in a Class of Transcription Factors, the LIM Homeodomain Proteins, in Neural Cell Type Specification

    Article • Journal of Biological Chemistry, October 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Cy Jeffries

  32. The N-Terminal Domains of Myosin Binding Protein C Can Bind Polymorphically to F-Actin

    Article • Journal of Molecular Biology, September 2011, Elsevier

    Cy Jeffries

  33. The modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalis

    Article • Molecular Microbiology, August 2011, Wiley

    Cy Jeffries

  34. Activation of the Retroviral Budding Factor ALIX

    Article • Journal of Virology, June 2011, ASM Journals

    Cy Jeffries

  35. Invited review: Probing the structures of muscle regulatory proteins using small-angle solution scattering

    Article • Biopolymers, March 2011, Wiley

    Cy Jeffries

  36. Effects of Macromolecular Crowding on an Intrinsically Disordered Protein Characterized by Small-Angle Neutron Scattering with Contrast Matching

    Article • Biophysical Journal, February 2011, Elsevier

    Cy Jeffries

  37. The Macromolecular Architecture of Extracellular Domain of αNRXN1: Domain Organization, Flexibility, and Insights into Trans-Synaptic Disposition

    Article • Structure, August 2010, Elsevier

    Cy Jeffries

  38. Calmodulin Disrupts the Structure of the HIV-1 MA Protein

    Article • Journal of Molecular Biology, July 2010, Elsevier

    Professor Jules Mitchell Guss, Cy Jeffries

  39. LIM Domain Binding Proteins 1 and 2 Have Different Oligomeric States

    Article • Journal of Molecular Biology, May 2010, Elsevier

    Cy Jeffries

  40. A picornaviral loop-to-loop replication complex

    Article • Journal of Structural Biology, June 2009, Elsevier

    Cy Jeffries

  41. Competition between LIM-binding domains

    Article • Biochemical Society Transactions, December 2008, Portland Press Ltd.

    Dr Daniel P Ryan, Cy Jeffries

  42. Histidine Kinase Regulation by a Cyclophilin-like Inhibitor

    Article • Journal of Molecular Biology, December 2008, Elsevier

    Cy Jeffries

  43. Cardiac myosin-binding protein C decorates F-actin: Implications for cardiac function

    Article • Proceedings of the National Academy of Sciences, November 2008, Proceedings of the National Academy of Sciences

    Cy Jeffries

  44. Small-Angle X-ray Scattering Reveals the N-Terminal Domain Organization of Cardiac Myosin Binding Protein C

    Article • Journal of Molecular Biology, April 2008, Elsevier

    Cy Jeffries

  45. Ligand-induced Conformational Changes via Flexible Linkers in the Amino-terminal region of the Inositol 1,4,5-Trisphosphate Receptor

    Article • Journal of Molecular Biology, November 2007, Elsevier

    Cy Jeffries

  46. Stabilization of a binary protein complex by intein-mediated cyclization

    Article • Protein Science, November 2006, Wiley

    Cy Jeffries

  47. MICREDOX®—development of a ferricyanide-mediated rapid biochemical oxygen demand method using an immobilised Proteus vulgaris biocomponent

    Article • Biosensors and Bioelectronics, October 2004, Elsevier

    Cy Jeffries

  48. Of barn owls and bankers: a lush variety of α/β hydrolases

    Article • Structure, June 1999, Elsevier

    Cy Jeffries

  49. Characterisation of a thermophilic L-glutamate dehydrogenase biosensor for amperometric determination of L-glutamate by flow injection analysis

    Article • Biosensors and Bioelectronics, February 1999, Elsevier

    Cy Jeffries

  50. Evaluation of a thermophile enzyme for a carbon paste amperometric biosensor: L-glutamate dehydrogenase

    Article • Biosensors and Bioelectronics, January 1997, Elsevier

    Cy Jeffries