All Stories

  1. Novel drugs targeting a major asthma trigger inhibit acute allergen challenge in experimental models

    Article • International Journal of Molecular Sciences, October 2018, MDPI AG

    Clive Robinson

  2. Targeting the root of allergic asthma

    Article • Molecular Pharmacology, July 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Clive Robinson

  3. Pathways of airway oxidant formation by house dust mite allergens and viral RNA converge through myosin motors, pannexons and Toll-like receptor 4

    Article • Immunity Inflammation and Disease, March 2018, Wiley

    Clive Robinson

  4. Allergen-dependent oxidant formation requires purinoceptor activation of ADAM 10 and prothrombin

    Article • Journal of Allergy and Clinical Immunology, June 2017, Elsevier

    Clive Robinson

  5. Indoor and Outdoor Allergens and Pollutants

    Article • January 2017, Elsevier

    Clive Robinson

  6. Innate generation of thrombin and intracellular oxidants in airway epithelium by allergen Der p 1

    Article • Journal of Allergy and Clinical Immunology, October 2016, Elsevier

    Clive Robinson

  7. The Discovery of Potent, Selective, and Reversible Inhibitors of the House Dust Mite Peptidase Allergen Der p 1: An Innovative Approach to the Treatment of Allergic Asthma

    Article • Journal of Medicinal Chemistry, November 2014, American Chemical Society (ACS)

    Clive Robinson

  8. Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans disease

    Article • BMC Infectious Diseases, April 2014, Springer Science + Business Media

    Clive Robinson

  9. The Structure and Function of Allergens

    Article • January 2014, Elsevier

    Clive Robinson

  10. Microbiological, Histological, Immunological, and Toxin Response to Antibiotic Treatment in the Mouse Model of Mycobacterium ulcerans Disease

    Article • PLoS Neglected Tropical Diseases, March 2013, PLOS

    Clive Robinson

  11. Nonhuman targets in allergic lung conditions

    Article • Future Medicinal Chemistry, February 2013, Future Science

    Clive Robinson

  12. Future inhaled drugs by virtual innovation: allergen delivery inhibitors

    Article • Future Medicinal Chemistry, October 2011, Future Science

    Clive Robinson

  13. Comparative enzymology of native and recombinant house dust mite allergen Der p 1

    Article • Allergy, March 2009, Wiley

    Clive Robinson

  14. Interactions between mature Der p 1 and its free prodomain indicate membership of a new family of C1 peptidases

    Article • Allergy, November 2007, Wiley

    Clive Robinson

  15. Pollen proteolytic enzymes degrade tight junctions

    Article • Respirology, November 2007, Wiley

    Clive Robinson

  16. Leukotriene C4 and histamine in early allergic reaction in the nose

    Article • Allergy, April 2007, Wiley

    Clive Robinson

  17. Peptidase allergen Der p 1 initiates apoptosis of epithelial cells independently of tight junction proteolysis

    Article • Molecular Membrane Biology, January 2003, Taylor & Francis

    Clive Robinson

  18. The immunobiology of allergenic peptidases

    Article • Clinical & Experimental Allergy, January 2003, Wiley

    Clive Robinson

  19. Report on the potential allergenicity of genetically modified organisms and their products

    Article • Clinical & Experimental Allergy, August 2002, Wiley

    Clive Robinson

  20. Peptidase allergens, occludin and claudins. Do their interactions facilitate the development of hypersensitivity reactions at mucosal surfaces?

    Article • Clinical & Experimental Allergy, February 2001, Wiley

    Clive Robinson

  21. The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus

    Article • Clinical & Experimental Allergy, February 2001, Wiley

    Clive Robinson

  22. The 18-kDa form of cat allergen Felis domesticus 1 (Fel d 1) is associated with gelatin- and fibronectin-degrading activity

    Article • Clinical & Experimental Allergy, August 2000, Wiley

    Clive Robinson

  23. Tight junction properties of the immortalized human bronchial epithelial cell lines Calu‐3 and 16HBE14o‐

    Article • European Respiratory Journal, June 2000, European Respiratory Society (ERS)

    Clive Robinson

  24. Quantitative structural and biochemical analyses of tight junction dynamics following exposure of epithelial cells to house dust mite allergen Der p 1

    Article • Clinical & Experimental Allergy, May 2000, Wiley

    Clive Robinson

  25. Inhibition of gelatinase activity in human airway epithelial cells and fibroblasts by dexamethasone and beclomethasone

    Article • British Journal of Pharmacology, July 1999, Wiley

    Clive Robinson

  26. Proteinases and sensitization: house mites and enzyme detergents

    Article • Clinical & Experimental Allergy, February 1999, Wiley

    Clive Robinson

  27. Cell lines of pulmonary and non-pulmonary origin as tools to study the effects of house dust mite proteinases on the regulation of epithelial permeability

    Article • Clinical & Experimental Allergy, October 1998, Wiley

    Clive Robinson

  28. Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium

    Article • British Journal of Pharmacology, July 1998, Wiley

    Clive Robinson

  29. Epithelial repair in asthma. Do the benefits of house dust mite avoidance result from proteinase avoidance?

    Article • Clinical & Experimental Allergy, May 1998, Wiley

    Clive Robinson

  30. Inwardly rectifying whole cell potassium current in human blood eosinophils

    Article • The Journal of Physiology, January 1998, Wiley

    Clive Robinson

  31. On the potential significance of the enzymatic activity of mite allergens to immunogenicity. Clues to structure and function revealed by molecular characterization

    Article • Clinical & Experimental Allergy, January 1997, Wiley

    Clive Robinson

  32. Lipoxygenase inhibitory activity of U-66,858 and its deacetylated metabolite U-68,244 in human whole blood

    Article • Agents and Actions, March 1994, Springer Science + Business Media

    Clive Robinson

  33. Stimulated eosinophils and proteinases augment the transepithelial flux of albumin in bovine bronchial mucosa

    Article • British Journal of Pharmacology, October 1993, Wiley

    Clive Robinson

  34. A comparison of the effects of polyarginine and stimulated eosinophils on the responsiveness of the bovine isovolumic bronchial segment preparation

    Article • British Journal of Pharmacology, June 1993, Wiley

    Clive Robinson

  35. The bronchial epithelium as a target for inflammatory attack in asthma

    Article • Clinical & Experimental Allergy, May 1992, Wiley

    Clive Robinson

  36. Inflammatory mediators and cellular infiltration of the lungs in a guinea pig model of the late asthmatic reaction

    Article • Lung, December 1991, Springer Science + Business Media

    Clive Robinson

  37. In vitro modulation of the eosinophil-dependent enhancement of the permeability of the bronchial mucosa

    Article • British Journal of Pharmacology, October 1991, Wiley

    Clive Robinson

  38. Effect of mite allergen on permeability of bronchial mucosa

    Article • The Lancet, November 1990, Elsevier

    Clive Robinson

  39. Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9?,11?-PGF2 and PGF2?

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, May 1990, Springer Science + Business Media

    Clive Robinson

  40. The metabolism of prostaglandin D2 evidence for the sequential conversion by NADPH and NAD+ dependent pathways

    Article • Biochemical Pharmacology, October 1989, Elsevier

    Clive Robinson

  41. Comparative vascular effects of histamine, prostaglandin (PG) D2 and its metabolite 9alpha, 11beta-PGF2 in human skin

    Article • Clinical & Experimental Allergy, November 1988, Wiley

    Clive Robinson

  42. The metabolism of prostaglandin D2 after inhalation or intravenous infusion in normal men

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, November 1988, Elsevier

    Clive Robinson

  43. Organ selective conversion of prostaglandin D2 to 9α, 11β-prostaglandin F2 and its subsequent metabolism in rat, rabbit and guinea pig

    Article • Biochemical Pharmacology, October 1988, Elsevier

    Clive Robinson

  44. The contribution of mast cell mediators to acute allergic reactions in human skin and airways

    Article • Allergy, February 1988, Wiley

    Clive Robinson

  45. Prostaglandin D2 release from human skin mast cells in response to ionophore A23187

    Article • British Journal of Pharmacology, November 1987, Wiley

    Clive Robinson

  46. Effect of inhaled piriprost (U-60, 257) a novel leukotriene inhibitor, on allergen and exercise induced bronchoconstriction in asthma.

    Article • Thorax, October 1986, BMJ

    Clive Robinson

  47. Ionophore-dependent generation of eicosanoids in human dispersed lung cells

    Article • Biochemical Pharmacology, June 1986, Elsevier

    Clive Robinson

  48. Evidence against the formation of 13,14-dihydro-15-keto-prostaglandin F2α following inhalation of prostaglandin D2 in man

    Article • British Journal of Pharmacology, March 1986, Wiley

    Clive Robinson

  49. The mast cell as a primary effector cell in the pathegenesis of asthma

    Article • Journal of Allergy and Clinical Immunology, February 1986, Elsevier

    Clive Robinson

  50. Oxidative transformations of arachidonic acid in human dispersed lung cells: disparity between the utilization of endogenous and exogenous substrate

    Article • British Journal of Pharmacology, October 1985, Wiley

    Clive Robinson

  51. New perspectives on the putative role of eicosanoids in airway hyperresponsiveness

    Article • Journal of Allergy and Clinical Immunology, August 1985, Elsevier

    Clive Robinson

  52. Pulmonary synthesis, release, and metabolism of prostaglandins

    Article • Journal of Allergy and Clinical Immunology, August 1985, Elsevier

    Clive Robinson

  53. Relationship between Mediator Release from Human Lung Mast Cells in vitro and in vivo

    Article • International Archives of Allergy and Immunology, January 1985, Karger Publishers

    Clive Robinson

  54. 6,9-deepoxy-6,9-(phenylimino)-Δ6,8-Prostaglandin I1, (U-60, 257) stimulates prostaglandin D2 and inhibits thromboxane B2 release from ionophore challenged human dispersed lung cells

    Article • British Journal of Pharmacology, November 1984, Wiley

    Clive Robinson

  55. Quantitative analysis of prostanoids in biological fluids by combined capillary column gas chromatography negative ion chemical ionization mass spectrometry

    Article • Journal of Mass Spectrometry, February 1984, Wiley

    Clive Robinson

  56. Total profiling by GC/NICIMS of the major cyclo-oxygenase products from antigen and leukotriene-challenged guinea-pig lung

    Article • Biochemical Pharmacology, February 1984, Elsevier

    Clive Robinson

  57. Thromboxane A2 analogues inhibit the metabolism of thromboxane B2 in perfused guinea-pig lung

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, November 1983, Elsevier

    Clive Robinson

  58. Action of 3-Isobutyl-1-Methylxanthine and Prostaglandins D2 and E1 on Histamine Release from Rat and Guinea Pig Mast Cells

    Article • International Archives of Allergy and Immunology, January 1983, Karger Publishers

    Clive Robinson

  59. Quantitative analysis of arachidonic acid metabolites in complex biological fluids using capillary gas chromatography/negative ion chemical ionisation mass spectrometry

    Article • International Journal of Mass Spectrometry and Ion Physics, January 1983, Elsevier

    Clive Robinson

  60. Selective inhibition of thromboxane B2 accumulation and metabolism in perfused guinea-pig lung

    Article • British Journal of Pharmacology, January 1983, Wiley

    Clive Robinson

  61. Comparison of pulmonary prostaglandin inactivation in normal and sensitized guinea-pig lungs

    Article • Journal of Pharmacy and Pharmacology, August 1982, Wiley

    Clive Robinson

  62. Thromboxane B2 uptake and metabolism in isolated perfused lung identification and comparison with prostaglandin F2α

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, August 1982, Elsevier

    Clive Robinson

  63. Inactivation of prostaglandins in the perfused rat lung

    Article • Biochemical Pharmacology, March 1982, Elsevier

    Clive Robinson

  64. Evidence for functionally distinct pools of phospholipase responsible for prostaglandin release from the perfused guinea-pig lung

    Article • European Journal of Pharmacology, June 1980, Elsevier

    Clive Robinson

  65. Interactions between Allergens and the Airway Epithelium

    Article • Wiley

    Clive Robinson