All Stories

  1. CRISPR technology for diagnosis and treatment of human brucellosis

    Article • Journal of Microbiological Methods, January 2026, Elsevier

    Cia-Hin Lau

  2. CRISPR/Dx-based colorimetric and electrochemical detection systems for POCT applications

    Article • Biosensors and Bioelectronics, November 2025, Elsevier

    Cia-Hin Lau

  3. CRISPR-based platforms for detecting tumor-associated genetic materials in clinical samples

    Article • Bioanalysis, October 2025, Taylor & Francis

    Cia-Hin Lau

  4. Pan-cancer methylation analysis of circulating cell-free DNA

    Article • Cancer Genetics, September 2025, Elsevier

    Cia-Hin Lau

  5. Recent Advances in Gene Therapy for Hemophilia

    Article • Clinical and Applied Thrombosis/Hemostasis, August 2025, SAGE Publications

    Cia-Hin Lau

  6. CRISPR/Cas-based personal glucose meters for nucleic acid detection

    Article • Trends in Biotechnology, July 2025, Elsevier

    Cia-Hin Lau

  7. A radiation toxicity biosensing platform based on radioresistant bacteria modified with dr_0423

    Article • Sensors and Actuators B Chemical, June 2025, Elsevier

    Cia-Hin Lau

  8. Artificial base mismatches-mediated PCR (ABM-PCR) for detecting clinically relevant single-base mutations

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), March 2025, De Gruyter

    Cia-Hin Lau

  9. Blood cancer therapy with synthetic receptors and CRISPR technology

    Article • Leukemia Research, March 2025, Elsevier

    Cia-Hin Lau

  10. CRISPR detection of cardiac tumor-associated microRNAs

    Article • Molecular Biology Reports, January 2025, Springer Science + Business Media

    Cia-Hin Lau

  11. One-pot isothermal CRISPR/Dx system for specific and sensitive detection of microRNA

    Article • Analytical Methods, January 2025, Royal Society of Chemistry

    Cia-Hin Lau

  12. Rapid, multiplex, one-pot CRISPR/Dx system for detecting cancer fusion genes

    Article • Analytical Methods, January 2025, Royal Society of Chemistry

    Cia-Hin Lau

  13. UV radiation enhanced encapsulation of superparamagnetic iron oxide nanoparticles (MNPs) in microparticles derived from tumor repopulating cells

    Article • Biochemical and Biophysical Research Communications, December 2024, Elsevier

    Cia-Hin Lau

  14. SynNotch-Programmed Macrophages for Cancerous Cell Detection and Sensing

    Article • ACS Sensors, November 2024, American Chemical Society (ACS)

    Cia-Hin Lau

  15. Amplification-free nucleic acids detection with next-generation CRISPR/dx systems

    Article • Critical Reviews in Biotechnology, September 2024, Taylor & Francis

    Cia-Hin Lau

  16. Extended replicative lifespan of primary resting T cells by CRISPR/dCas9-based epigenetic modifiers and transcriptional activators

    Article • Cellular and Molecular Life Sciences, September 2024, Springer Science + Business Media

    Cia-Hin Lau

  17. Next-generation CRISPR technology for genome, epigenome and mitochondrial editing

    Article • Transgenic Research, August 2024, Springer Science + Business Media

    Cia-Hin Lau

  18. Development of a baculoviral CRISPR/Cas9 vector system for beta-2-microglobulin knockout in human pluripotent stem cells

    Article • Molecular Genetics and Genomics, August 2024, Springer Science + Business Media

    Cia-Hin Lau

  19. Rapid and Amplification-free Nucleic Acid Detection with DNA Substrate-Mediated Autocatalysis of CRISPR/Cas12a

    Article • ACS Omega, June 2024, American Chemical Society (ACS)

    Cia-Hin Lau

  20. Effects of Different Surface Functionalizations of Silica Nanoparticles on Mesenchymal Stem Cells

    Article • ACS Applied Bio Materials, May 2024, American Chemical Society (ACS)

    Cia-Hin Lau

  21. Multimodal detection of flap endonuclease 1 activity through CRISPR/Cas12a trans-cleavage of single-strand DNA oligonucleotides

    Article • Biosensors and Bioelectronics, January 2023, Elsevier

    Cia-Hin Lau

  22. Cellular uptake, tissue penetration, biodistribution, and biosafety of threose nucleic acids: Assessing in vitro and in vivo delivery

    Article • Materials Today Bio, June 2022, Elsevier

    Cia-Hin Lau

  23. PAM-flexible dual base editor-mediated random mutagenesis and self-activation strategies to improve CRISPRa potency

    Article • Molecular Therapy — Methods & Clinical Development, May 2022, Elsevier

    Cia-Hin Lau

  24. Targeted brain tumor imaging by using discrete biopolymer-coated nanodiamonds across the blood–brain barrier

    Article • Nanoscale, January 2021, Royal Society of Chemistry

    Cia-Hin Lau

  25. CRISPR-based transgene knock-in and gene correction

    Article • Faculty Reviews, December 2020, F1000Research

    Cia-Hin Lau

  26. Correction to Penetrating the Blood–Brain Barrier by Self-Assembled 3D DNA Nanocages as Drug Delivery Vehicles for Brain Cancer Therapy

    Article • ACS Applied Materials & Interfaces, September 2020, American Chemical Society (ACS)

    Cia-Hin Lau

  27. Penetrating the Blood–Brain Barrier by Self-Assembled 3D DNA Nanocages as Drug Delivery Vehicles for Brain Cancer Therapy

    Article • ACS Applied Materials & Interfaces, June 2020, American Chemical Society (ACS)

    Cia-Hin Lau

  28. Synthetic α-l-Threose Nucleic Acids Targeting BcL-2 Show Gene Silencing and in Vivo Antitumor Activity for Cancer Therapy

    Article • ACS Applied Materials & Interfaces, September 2019, American Chemical Society (ACS)

    Cia-Hin Lau

  29. The Synergy between CRISPR and Chemical Engineering

    Article • Current Gene Therapy, July 2019, Bentham Science Publishers

    Cia-Hin Lau

  30. Targeted Transgene Activation in the Brain Tissue by Systemic Delivery of Engineered AAV1 Expressing CRISPRa

    Article • Molecular Therapy — Nucleic Acids, April 2019, Elsevier

    Cia-Hin Lau

  31. Diverse CRISPR Applications

    Article • The CRISPR Journal, December 2018, Mary Ann Liebert Inc

    Cia-Hin Lau

  32. In vivo epigenome editing and transcriptional modulation using CRISPR technology

    Article • Transgenic Research, October 2018, Springer Science + Business Media

    Cia-Hin Lau

  33. Dual-Function, Cationic, Peptide-Coated Nanodiamond Systems: Facilitating Nuclear-Targeting Delivery for Enhanced Gene Therapy Applications

    Article • ACS Sustainable Chemistry & Engineering, July 2018, American Chemical Society (ACS)

    Cia-Hin Lau

  34. In vivo genome editing using AAV-CRISPR system

    Article • F1000Research, December 2017, Faculty of 1000, Ltd.

    Cia-Hin Lau, Yousin Suh

  35. Epigenetic studies using CRISPR technology

    Article • Mammalian Genome, December 2017, Springer Science + Business Media

    Cia-Hin Lau

  36. Human aging research using CRISPR technology

    Article • Gerontology, December 2016, Karger Publishers

    Cia-Hin Lau

  37. microRNA research using artificial microRNA sponges

    Article • Advanced Drug Delivery Reviews, January 2015, Elsevier

    Cia-Hin Lau

  38. Optimization of baculoviral-TALEN system

    Article • Molecular Therapy — Methods & Clinical Development, January 2014, Elsevier

    Cia-Hin Lau

  39. Cellular reprogramming using baculoviral-ZFN system

    Article • Stem Cells Translational Medicine, October 2013, Wiley

    Cia-Hin Lau

  40. Genetic manipulation of human iPSCs using baculoviral-ZFN system

    Article • The Journal of Gene Medicine, October 2013, Wiley

    Cia-Hin Lau

  41. Genetic manipulation of human iPSCs using baculoviral-TALEN system

    Article • Nucleic Acids Research, August 2013, Oxford University Press (OUP)

    Cia-Hin Lau

  42. Association of adiponectin and resistin gene polymorphisms with metabolic syndrome phenotypes

    Article • Biochemical Genetics, November 2012, Springer Science + Business Media

    Cia-Hin Lau

  43. Epistatic interactions between adiponectin and resistin gene polymorphisms

    Article • Genetics and Molecular Biology, January 2012, FapUNIFESP (SciELO)

    Cia-Hin Lau

  44. Association of adiponectin and resistin gene polymorphisms with adipokine levels

    Article • Annals of Human Genetics, February 2011, Wiley

    Cia-Hin Lau

  45. Novel adiponectin-resistin and insulin resistance indexes

    Article • Cardiovascular Diabetology, January 2011, Springer Science + Business Media

    Cia-Hin Lau