All Stories

  1. Deep learning-based stress detection from RR intervals in major depressive disorder, panic disorder, and healthy individuals

    Article • Frontiers in Psychiatry, September 2025, Frontiers

    Chul-Hyun Cho

  2. Editorial: Addictive disorders and digital medicine: technology-based solutions for addictive disorders

    Article • Frontiers in Psychiatry, September 2025, Frontiers

    Chul-Hyun Cho

  3. Mental health risks associated with a family history of chronic diseases: A nationwide population-based cross-sectional study

    Article • Journal of Psychosomatic Research, September 2025, Elsevier

    Chul-Hyun Cho

  4. Optimizing Winter‐Type Seasonality Criteria in East Asian Populations: A Machine Learning Approach Using the Seasonal Pattern Assessment Questionnaire

    Article • Brain and Behavior, September 2025, Wiley

    Chul-Hyun Cho

  5. Transcutaneous auricular vagus nerve stimulation (taVNS) improves sleep quality in chronic insomnia disorder: A double-blind, randomized, sham-controlled trial

    Article • Sleep Medicine, September 2025, Elsevier

    Chul-Hyun Cho

  6. The reliability and validity of the Korean version of the sleep health index using self-report measures and wearable-derived sleep metrics

    Article • Sleep And Breathing, August 2025, Springer Science + Business Media

    Chul-Hyun Cho

  7. Development of prediction models for screening depression and anxiety using smartphone and wearable-based digital phenotyping: protocol for the Smartphone and Wearable Assessment for Real-Time Screening of Depression and Anxiety (SWARTS-DA) observation...

    Article • BMJ Open, June 2025, BMJ

    Chul-Hyun Cho

  8. Machine learning-based prediction of restless legs syndrome using digital phenotypes from wearables and smartphone data

    Article • Scientific Reports, May 2025, Springer Science + Business Media

    Chul-Hyun Cho

  9. Development and Validation of a Wearable-Based Monitoring System for Predicting Psychiatric Crises in Inpatients: Study Protocol

    Article • Chronobiology in Medicine, March 2025, Chronobiology in Medicine

    Chul-Hyun Cho

  10. Exploring User Experience and the Therapeutic Relationship of Short-Term Avatar-Based Psychotherapy: Qualitative Pilot Study

    Article • JMIR Human Factors, February 2025, JMIR Publications Inc.

    Chul-Hyun Cho

  11. EXPLORING THE FEASIBILITY OF INSOMNIA SUBTYPING USING MACHINE LEARNING CLUSTERING BASED ON DIGITAL PHENOTYPE DATA

    Article • The International Journal of Neuropsychopharmacology, February 2025, Oxford University Press (OUP)

    Chul-Hyun Cho

  12. Exploring the Psychological and Physiological Insights Through Digital Phenotyping by Analyzing the Discrepancies Between Subjective Insomnia Severity and Activity-Based Objective Sleep Measures: Observational Cohort Study

    Article • JMIR Mental Health, January 2025, JMIR Publications Inc.

    Chul-Hyun Cho

  13. A New Agenda for Optimizing Roles and Infrastructure in a Mental Health Service Model for South Korea

    Article • Psychiatry Investigation, January 2025, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  14. Therapeutic Potential of Social Chatbots in Alleviating Loneliness and Social Anxiety: Quasi-Experimental Mixed Methods Study

    Article • Journal of Medical Internet Research, January 2025, JMIR Publications Inc.

    Chul-Hyun Cho

  15. Automated classification of stress and relaxation responses in major depressive disorder, panic disorder, and healthy participants via heart rate variability

    Article • Frontiers in Psychiatry, January 2025, Frontiers

    Chul-Hyun Cho

  16. Machine learning prediction of anxiety symptoms in social anxiety disorder: utilizing multimodal data from virtual reality sessions

    Article • Frontiers in Psychiatry, January 2025, Frontiers

    Chul-Hyun Cho

  17. Why Behavioral Medicine Is Critical for Circadian Health in the Digital Era?

    Article • Chronobiology in Medicine, December 2024, Chronobiology in Medicine

    Chul-Hyun Cho

  18. Early Prediction of Depressive Episodes in Mood Disorders Using Circadian Rhythm Indicators and Deep Learning

    Article • December 2024, Institute of Electrical & Electronics Engineers (IEEE)

    Chul-Hyun Cho

  19. Mental Health Status Profiles of Dentists in South Korea: A Latent Profile Analysis Approach

    Article • Psychiatry Investigation, November 2024, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  20. A digital phenotyping dataset for impending panic symptoms: a prospective longitudinal study

    Article • Scientific Data, November 2024, Springer Science + Business Media

    Chul-Hyun Cho

  21. Accurately predicting mood episodes in mood disorder patients using wearable sleep and circadian rhythm features

    Article • npj Digital Medicine, November 2024, Springer Science + Business Media

    Chul-Hyun Cho

  22. Breast cancer risk among women with schizophrenia and association with duration of antipsychotic use: population-based cohort study in South Korea

    Article • The British Journal of Psychiatry, October 2024, Royal College of Psychiatrists

    Chul-Hyun Cho

  23. Childhood maltreatment and suicide attempts in major depression and bipolar disorders in South Korea: A prospective nationwide cohort study

    Article • Journal of Affective Disorders, September 2024, Elsevier

    Chul-Hyun Cho

  24. Daily Self-Monitoring and Feedback of Circadian Rhythm Measures in Major Depression and Bipolar Disorder Using Wearable Devices and Smartphones–The Circadian Rhythm for Mood (CRM®) Trial Protocol: A Randomized Sham Controlled Double-Blind Trial

    Article • Psychiatry Investigation, August 2024, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  25. Herbal and Natural Supplements for Improving Sleep: A Literature Review

    Article • Psychiatry Investigation, August 2024, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  26. Causal dynamics of sleep, circadian rhythm, and mood symptoms in patients with major depression and bipolar disorder: insights from longitudinal wearable device data

    Article • EBioMedicine, May 2024, Elsevier

    Chul-Hyun Cho

  27. Identifying predictive factors for mood recurrence in early-onset major mood disorders: A 4-year, multicenter, prospective cohort study

    Article • Psychiatry Research, May 2024, Elsevier

    Chul-Hyun Cho

  28. Psychosocial and digital intervention for patients with schizophrenia

    Article • Journal of Korean Medical Association, February 2024, Korean Medical Association (KAMJE)

    Chul-Hyun Cho

  29. Effects of a Rice-Farming Simulation Video Game on Nature Relatedness, Nutritional Status, and Psychological State in Urban-Dwelling Adults During the COVID-19 Pandemic: Randomized Waitlist Controlled Trial

    Article • Journal of Medical Internet Research, January 2024, JMIR Publications Inc.

    Chul-Hyun Cho

  30. Machine Learning Prediction of Impending Panic Symptoms Using Digital Phenotypes: From Over 2-Year Prospective Longitudinal Data

    Article • January 2024, Elsevier

    Chul-Hyun Cho

  31. Telepsychiatry in the Treatment of Major Depressive Disorders

    Article • January 2024, Springer Science + Business Media

    Chul-Hyun Cho

  32. The New Emerging Treatment Choice for Major Depressive Disorders: Digital Therapeutics

    Article • January 2024, Springer Science + Business Media

    Chul-Hyun Cho

  33. Association between social networks and symptoms of post-traumatic stress during the pandemic: Cohort study in South Korea

    Article • Comprehensive Psychiatry, November 2023, Elsevier

    Chul-Hyun Cho

  34. Beyond misconceptions and prejudices – Understanding North Korean mental health from journals in North Korea

    Article • Asian Journal of Psychiatry, October 2023, Elsevier

    Chul-Hyun Cho

  35. Revolutionizing Sleep Health: The Promise and Challenges of Digital Phenotyping

    Article • Chronobiology in Medicine, September 2023, Chronobiology in Medicine

    Chul-Hyun Cho

  36. Potential effectiveness of digital therapeutics specialized in executive functions as adjunctive treatment for clinical symptoms of attention-deficit/hyperactivity disorder: a feasibility study

    Article • Frontiers in Psychiatry, July 2023, Frontiers

    Chul-Hyun Cho

  37. Machine Learning–Based Prediction of Attention-Deficit/Hyperactivity Disorder and Sleep Problems With Wearable Data in Children

    Article • JAMA Network Open, March 2023, American Medical Association (AMA)

    Chul-Hyun Cho

  38. The Beginning of the Era of Digital Therapeutics in Korea: Challenges and Opportunities

    Article • Journal of Korean Medical Science, January 2023, XMLink

    Chul-Hyun Cho

  39. Association Between Benzodiazepines and Dementia in South Korea: A Nation-Wide Study

    Article • Chronobiology in Medicine, December 2022, Chronobiology in Medicine

    Chul-Hyun Cho

  40. The relationship between morningness-eveningness and mood symptoms and quality of life in euthymic state of mood disorders: Results from a prospective observational cohort study

    Article • Journal of Affective Disorders, November 2022, Elsevier

    Chul-Hyun Cho

  41. No Association Between NPAS2 rs6425296 Polymorphism and Seasonality, Diurnal Preference in Koreans

    Article • Chronobiology in Medicine, September 2022, Chronobiology in Medicine

    Chul-Hyun Cho

  42. Prediction of impending mood episode recurrence using real-time digital phenotypes in major depression and bipolar disorders in South Korea: a prospective nationwide cohort study

    Article • Psychological Medicine, September 2022, Cambridge University Press

    Chul-Hyun Cho

  43. Prediction of Specific Anxiety Symptoms and Virtual Reality Sickness Using In Situ Autonomic Physiological Signals During Virtual Reality Treatment in Patients With Social Anxiety Disorder: Mixed Methods Study

    Article • JMIR Serious Games, September 2022, JMIR Publications Inc.

    Chul-Hyun Cho

  44. Design and Methods of a Prospective Smartphone App-Based Study for Digital Phenotyping of Mood and Anxiety Symptoms Mixed With Centralized and Decentralized Research Form: The Search Your Mind (S.Y.M., 心) Project

    Article • Psychiatry Investigation, July 2022, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  45. Identification of Healthy and Unhealthy Lifestyles by a Wearable Activity Tracker in Type 2 Diabetes: A Machine Learning-Based Analysis

    Article • Endocrinology and Metabolism, June 2022, Korean Endocrine Society (KAMJE)

    Chul-Hyun Cho

  46. Quetiapine as a Potential Treatment for Insomnia: The Road Ahead

    Article • Chronobiology in Medicine, June 2022, Chronobiology in Medicine

    Chul-Hyun Cho

  47. Mediation Effect of Insomnia Symptoms on Relation Between Stress and Quality of Life

    Article • Psychiatry Investigation, March 2022, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  48. Cognitive Remediation Therapy for Cognitive Dysfunction in Patients With Major Depressive Disorder

    Article • Psychiatric Annals, March 2022, SLACK, Inc.

    Chul-Hyun Cho

  49. The Effects of Virtual Reality Treatment on Prefrontal Cortex Activity in Patients With Social Anxiety Disorder: Participatory and Interactive Virtual Reality Treatment Study

    Article • Journal of Medical Internet Research, December 2021, JMIR Publications Inc.

    Chul-Hyun Cho

  50. Association Between CLOCK Gene Variants and Restless Legs Syndrome in Koreans

    Article • Psychiatry Investigation, November 2021, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  51. Virtual Reality–Based Psychotherapy in Social Anxiety Disorder: fMRI Study Using a Self-Referential Task

    Article • JMIR Mental Health, April 2021, JMIR Publications Inc.

    Chul-Hyun Cho

  52. Bipolar II disorder has the highest prevalence of seasonal affective disorder in early‐onset mood disorders: Results from a prospective observational cohort study

    Article • Depression and Anxiety, April 2021, Wiley

    Chul-Hyun Cho

  53. Applying Circadian Rhythm Concepts in Digital Healthcare

    Article • Chronobiology in Medicine, March 2021, Chronobiology in Medicine

    Chul-Hyun Cho

  54. Impact of Exposure to Dim Artificial Light at Night during Sleep on Cognitive Function

    Article • Chronobiology in Medicine, December 2020, Chronobiology in Medicine

    Chul-Hyun Cho

  55. Effects of Immersive Virtual Reality Content Type to Mindfulness and Physiological Parameters

    Article • November 2020, ACM (Association for Computing Machinery)

    Chul-Hyun Cho

  56. Association between the IL10 rs1800896 Polymorphism and Tardive Dyskinesia in Schizophrenia

    Article • Psychiatry Investigation, October 2020, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  57. Effectiveness of a Participatory and Interactive Virtual Reality Intervention in Patients With Social Anxiety Disorder: Longitudinal Questionnaire Study

    Article • Journal of Medical Internet Research, October 2020, JMIR Publications Inc.

    Chul-Hyun Cho

  58. Circadian Rhythm of Heart Rate Assessed by Wearable Devices Tends to Correlate with the Circadian Rhythm of Salivary Cortisol Concentration in Healthy Young Adults

    Article • Chronobiology in Medicine, September 2020, Chronobiology in Medicine

    Chul-Hyun Cho

  59. Psychological characteristics and associations between living kidney transplantation recipients and biologically related or unrelated donors

    Article • BMC Nephrology, August 2020, Springer Science + Business Media

    Chul-Hyun Cho

  60. Effectiveness of a Smartphone App With a Wearable Activity Tracker in Preventing the Recurrence of Mood Disorders: Prospective Case-Control Study

    Article • JMIR Mental Health, August 2020, JMIR Publications Inc.

    Chul-Hyun Cho

  61. Development of model based on clock gene expression of human hair follicle cells to estimate circadian time

    Article • Chronobiology International, July 2020, Taylor & Francis

    Chul-Hyun Cho

  62. Early Onset Depression Has Different Characteristics from Middle-Aged Depression in Terms of Circadian Rhythm

    Article • Chronobiology in Medicine, March 2020, Chronobiology in Medicine

    Chul-Hyun Cho

  63. Temporal association between zolpidem medication and the risk of suicide: A 12-year population-based, retrospective cohort study

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Chul-Hyun Cho

  64. Similarities of Aspects of Biological Rhythms between Major Depression and Bipolar II Disorder Compared to Bipolar I Disorder: A Finding from the Early-Onset Mood Disorder Cohort

    Article • Psychiatry Investigation, November 2019, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  65. Circadian Gene Variations Are Associated with Obsessive-Compulsive Behaviors in a Young Healthy Korean Population

    Article • Chronobiology in Medicine, September 2019, Chronobiology in Medicine

    Chul-Hyun Cho

  66. The Chronobiologic-Based Practical Approach to Shift Work

    Article • Chronobiology in Medicine, September 2019, Chronobiology in Medicine

    Chul-Hyun Cho

  67. Addendum to the Acknowledgements: Mood prediction of patients with mood disorder by machine learning using passive digital phenotypes based on circadian rhythm: a prospective observational cohort study (Preprint)

    Article • Journal of Medical Internet Research, August 2019, JMIR Publications Inc.

    Chul-Hyun Cho

  68. Mood Prediction of Patients With Mood Disorders by Machine Learning Using Passive Digital Phenotypes Based on the Circadian Rhythm: Prospective Observational Cohort Study

    Article • Journal of Medical Internet Research, April 2019, JMIR Publications Inc.

    Chul-Hyun Cho

  69. A Genome-Wide Association Study of Bipolar Disorder Using a Subphenotype: Sleeplessness Symptom of Bipolar Mania

    Article • Chronobiology in Medicine, March 2019, Chronobiology in Medicine

    Chul-Hyun Cho

  70. Could Digital Therapeutics be a Game Changer in Psychiatry?

    Article • Psychiatry Investigation, February 2019, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  71. Visuo-Haptic-Based Multimodal Feedback Virtual Reality Solution to Improve Anxiety Symptoms: A Proof-of-Concept Study

    Article • Psychiatry Investigation, February 2019, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  72. Validation of the Korean Version of the Biological Rhythms Interview of Assessment in Neuropsychiatry

    Article • Psychiatry Investigation, December 2018, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  73. Development of a Modified Korean Version of the Epworth Sleepiness Scale Reflecting Korean Sociocultural Lifestyle

    Article • Psychiatry Investigation, July 2018, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  74. Impact of Exposure to Dim Light at Night on Sleep in Female and Comparison with Male Subjects

    Article • Psychiatry Investigation, May 2018, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  75. Why Do Mania and Suicide Occur Most Often in the Spring?

    Article • Psychiatry Investigation, March 2018, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  76. Association of G-Protein β3 Subunit C825T Polymorphism with Seasonal Variations in Mood and Behavior

    Article • Psychiatry Investigation, February 2018, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  77. Correlation of occupational stress with depression, anxiety, and sleep in Korean dentists: cross-sectional study

    Article • BMC Psychiatry, December 2017, Springer Science + Business Media

    Chul-Hyun Cho

  78. "Drop the beat"

    Article • November 2017, ACM (Association for Computing Machinery)

    Chul-Hyun Cho

  79. Association analysis ofANK3variants with bipolar disorder in the Korean population

    Article • Nordic Journal of Psychiatry, January 2017, Taylor & Francis

    Chul-Hyun Cho

  80. A Genome-Wide Association Study Identifies UTRN Gene Polymorphism for Restless Legs Syndrome in a Korean Population

    Article • Psychiatry Investigation, January 2017, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  81. Comparison of Wearable Activity Tracker with Actigraphy for Sleep Evaluation and Circadian Rest-Activity Rhythm Measurement in Healthy Young Adults

    Article • Psychiatry Investigation, January 2017, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  82. Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study

    Article • Psychiatry Investigation, January 2017, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  83. Individuals with Restless Legs Syndrome Tend to have Severe Depressive Symptoms: Findings from a Community-Based Cohort Study

    Article • Psychiatry Investigation, January 2017, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  84. Solar radiation increases suicide rate after adjusting for other climate factors in South Korea

    Article • Acta Psychiatrica Scandinavica, December 2016, Wiley

    Chul-Hyun Cho, Heon Jeong Lee

  85. Decrease in fMRI brain activation during working memory performed after sleeping under 10 lux light

    Article • Scientific Reports, November 2016, Springer Science + Business Media

    Chul-Hyun Cho

  86. Association of CLOCK, ARNTL, PER2, and GNB3 polymorphisms with diurnal preference in a Korean population

    Article • Chronobiology International, September 2016, Taylor & Francis

    Chul-Hyun Cho

  87. Advanced Circadian Phase in Mania and Delayed Circadian Phase in Mixed Mania and Depression Returned to Normal after Treatment of Bipolar Disorder

    Article • EBioMedicine, September 2016, Elsevier

    Chul-Hyun Cho

  88. Molecular circadian rhythm shift due to bright light exposure before bedtime is related to subthreshold bipolarity

    Article • Scientific Reports, August 2016, Springer Science + Business Media

    Chul-Hyun Cho

  89. Association ofCACNA1CVariants with Bipolar Disorder in the Korean Population

    Article • Psychiatry Investigation, January 2016, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  90. Review of Cohort Studies for Mood Disorders

    Article • Psychiatry Investigation, January 2016, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  91. Sleep Irregularity in the Previous Week Influences the First-Night Effect in Polysomnographic Studies

    Article • Psychiatry Investigation, January 2016, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  92. Exposure to dim artificial light at night increases REM sleep and awakenings in humans

    Article • Chronobiology International, December 2015, Taylor & Francis

    Chul-Hyun Cho

  93. Association ofCLOCK, ARNTL, andNPAS2gene polymorphisms and seasonal variations in mood and behavior

    Article • Chronobiology International, July 2015, Taylor & Francis

    Chul-Hyun Cho

  94. A Comparison of Personality Characteristics and Psychiatric Symptomatology between Upper Airway Resistance Syndrome and Obstructive Sleep Apnea Syndrome

    Article • Psychiatry Investigation, January 2015, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  95. CDH13andHCRTR2May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway Analysis

    Article • Psychiatry Investigation, January 2015, Korean Neuropsychiatric Association

    Chul-Hyun Cho

  96. Association between restless legs syndrome andCLOCKandNPAS2gene polymorphisms in schizophrenia

    Article • Chronobiology International, May 2014, Taylor & Francis

    Chul-Hyun Cho

  97. Oxidative stress and tardive dyskinesia: Pharmacogenetic evidence

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, October 2013, Elsevier

    Chul-Hyun Cho

  98. Association between Antipsychotics-Induced Restless Legs Syndrome and Tyrosine Hydroxylase Gene Polymorphism

    Article • Psychiatry Investigation, January 2009, Korean Neuropsychiatric Association

    Chul-Hyun Cho