All Stories

  1. Analytical validation of a dried blood microsampling method to measure androstenedione, 17α‑hydroxyprogesterone, and 11‑ketotestosterone for congenital adrenal hyperplasia monitoring
  2. In vitro bioassays for measuring monoamine transporter function
  3. Reference values for the alcohol biomarker phosphatidylethanol (PEth) in the Belgian population: Insights from a nationwide microsampling study
  4. Explainable Artificial Intelligence (xAI) for 5-HT2A Receptor Binding Affinity of New Psychoactive Substances
  5. Commentary on Zhu et al .: Nitazenes—Tracking a moving target from linked United States databases
  6. Patient-centric capillary dried blood spot sampling for tacrolimus and creatinine monitoring in clinical practice
  7. N -Benzyl-Tryptamine Derivatives as Serotonin 5-HT 2 Receptor Ligands: Synthesis and Structure-Affinity/Activity Relationships
  8. Capillary dried blood microsampling is not suited for dihydropyrimidine dehydrogenase (DPD) phenotyping
  9. Determination of vitamin D and its metabolites using capillary dried blood microsampling: are we there yet?
  10. TRACT assay-based in vitro characterization of substituted cathinones: inhibition and release at the serotonin transporter
  11. N -Benzyl-tryptamine Derivatives as Serotonin 5-HT 2A Receptor (5-HT 2A R) Agonists: Focus on Different In Vitro 5-HT ...
  12. Sleep, wake, and signaling: Functional profiling of orexin agonists and antagonists using newly developed orexin β-arrestin 2 and miniGαq recruitment assays
  13. Thiamine status in Belgian adults assessed by volumetric absorptive microsampling: a nation-wide cross-sectional survey
  14. Live cell luminescence-based Gαq-PLC-β interaction assay: development and application at the serotonin 5-HT2A receptor
  15. Small Changes, Big Consequences? Assessment of the Impact of Design Changes in Microsampling Devices
  16. Clinical validation of a DBS-based LC-MS/MS method for 25-hydroxyvitamin D: from lab sampling to home sampling
  17. Comparative Evaluation of Approaches to Convert Microsampled Capillary Blood Concentrations to Plasma Concentrations: Paracetamol and Metabolites as a Case Study
  18. The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects
  19. Fast and reliable in vitro activity-based detection of synthetic cannabinoid receptor agonists in e-liquids
  20. Outsmarting generic legislation: 4 years into the cat-and-mouse game of the synthetic cannabinoid receptor agonist market since the Chinese ban in 2021
  21. LC-MS/MS-based determination of 25-hydroxyvitamin D in dried blood spots: crucial importance of combining a robust extraction with knowledge of the hematocrit
  22. Navigating nitazenes: A pharmacological and toxicological overview of new synthetic opioids with a 2-benzylbenzimidazole core
  23. Setup and Evaluation of the TRACT Assay Principle for the In Vitro Functional Characterization of Modulators of the Serotonin Transporter and the Serotonin 2A Receptor
  24. “Do It Yourself” Synthetic Cannabinoid Receptor Agonist Precursors as a Ban‐Evading Strategy: Comparison of the Pharmacological Characteristics of Precursors and Their Final Products
  25. Design, Synthesis, and In Vitro Characterization of a Tryptamine-Based Visible-Light Photoswitchable 5-HT2AR Ligand Showing Efficacy Preference for β-Arrestin over Mini-Gq
  26. Synthesis, Pharmacological Characterization, and Binding Mode Analysis of 8-Hydroxy-Tetrahydroisoquinolines as 5-HT7 Receptor Inverse Agonists
  27. The ‘ABC’ of split-nanoluciferase HIF heterodimerization bioassays: Applications, Benefits & Considerations
  28. Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity
  29. Cardiorespiratory effects of gamma-hydroxybutyric acid (GHB) during isoflurane anaesthesia in pigs
  30. Review on activity-based detection of doping substances and growth promotors in biological matrices: do bioassays deserve a place in control programs?
  31. Nitazene test strips: a laboratory evaluation
  32. Interpreting mono- and poly-SCRA intoxications from an activity-based point of view: JWH-018 equivalents in serum as a comparative measure
  33. Self-Sampling by Adolescents at Home: Assessment of the Feasibility to Successfully Collect Blood Microsamples by Inexperienced Individuals
  34. Activity-based detection of synthetic cannabinoid receptor agonists in plant materials
  35. In vitro structure–activity relationships and forensic case series of emerging 2-benzylbenzimidazole ‘nitazene’ opioids
  36. Investigation of the intrinsic cannabinoid activity of hemp-derived and semisynthetic cannabinoids with β-arrestin2 recruitment assays—and how this matters for the harm potential of seized drugs
  37. Comparative Pharmacological Effects of Lisuride and Lysergic Acid Diethylamide Revisited
  38. Is the stability of folates in dried blood microsamples sufficient to perform home-sampling studies?
  39. Untargeted Detection of HIF Stabilizers in Doping Samples: Activity-Based Screening with a Stable In Vitro Bioassay
  40. In vitro cannabinoid activity profiling of generic ban‐evading brominated synthetic cannabinoid receptor agonists and their analogs
  41. Assay-Dependent Inverse Agonism at the A3 Adenosine Receptor: When Neutral Is Not Neutral
  42. In vitro cannabinoid receptor activity, metabolism, and detection in seized samples of CH‐PIATA, a new indole‐3‐acetamide synthetic cannabinoid
  43. In vitro μ‐opioid receptor activation potential of U10 and β‐U10, positional isomers of the synthetic opioid naphthyl U‐47700
  44. Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists
  45. Increasing Confidence in a Phosphatidylethanol 16:0/18:1 Cutoff at 20 ng/mL to Support Abstinence or Minor Intake of Alcohol
  46. Remote HbA1c testing via microsampling: fit for purpose?
  47. Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs
  48. Dual-Acting Small Molecules: Subtype-Selective Cannabinoid Receptor 2 Agonist/Butyrylcholinesterase Inhibitor Hybrids Show Neuroprotection in an Alzheimer’s Disease Mouse Model
  49. Off-target activity of NBOMes and NBOMe analogs at the µ opioid receptor
  50. Liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring of immunosuppressants and creatinine from a single dried blood spot using the Capitainer® qDBS device
  51. Comparison of near-infrared and UV–vis-based non-contact hematocrit prediction of dried blood spots from patients on immunosuppressants
  52. Application of a Volumetric Absorptive Microsampling (VAMS)-Based Method for the Determination of Paracetamol and Four of its Metabolites as a Tool for Pharmacokinetic Studies in Obese and Non-Obese Patients
  53. DRIED BLOOD MICROSAMPLING-ASSISTED THERAPEUTIC DRUG MONITORING OF IMMUNOSUPPRESSANTS: AN OVERVIEW
  54. Application OF NON-CONTACT hematocrit prediction technologies to overcome hematocrit effects on immunosuppressant quantification from dried blood spots
  55. Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists
  56. Linking in vitro and ex vivo CB1 activity with serum concentrations and clinical features in 5F-MDMB-PICA users to better understand SCRAs and their metabolites
  57. Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB1R) “Cis-On” Agonist
  58. Consensus for the use of the alcohol biomarker phosphatidylethanol (PEth) for the assessment of abstinence and alcohol consumption in clinical and forensic practice (2022 Consensus of Basel)
  59. In vitro functional assays as a tool to study new synthetic opioids at the μ-opioid receptor: Potential, pitfalls and progress
  60. Frontispiece: Enlightening the “Spirit Molecule”: Photomodulation of the 5‐HT 2A Receptor by a Light‐Controllable N , N ‐Dimethyltryptamine Derivative
  61. Frontispiz: Die Erhellung des “Bewusstseinsmoleküls”: Photomodulation des 5‐HT 2A Rezeptors durch ein licht‐steuerbares N,N‐Dimethyltryptamin‐Derivat
  62. Analytical performance of eight enzymatic assays for ethanol in serum evaluated by data from the Belgian external quality assessment scheme
  63. Promising Tools to Facilitate the Implementation of TDM of Biologics in Clinical Practice
  64. Cannabinoid receptor activation potential of the next generation, generic ban evading OXIZID synthetic cannabinoid receptor agonists
  65. A new cannabinoid receptor 1 selective agonist evading the 2021 ‘China ban’: ADB‐FUBIATA
  66. Die Erhellung des “Bewusstseinsmoleküls”: Photomodulation des 5‐HT 2A Rezeptors durch ein licht‐steuerbares N,N‐Dimethyltryptamin‐Derivat
  67. Enlightening the “Spirit Molecule”: Photomodulation of the 5‐HT 2A Receptor by a Light‐Controllable N , N ‐Dimethyltryptamine Derivative
  68. Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid
  69. First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass
  70. Machine Learning to Assist in Large-Scale, Activity-Based Synthetic Cannabinoid Receptor Agonist Screening of Serum Samples
  71. The P2Y2 Receptor C-Terminal Tail Modulates but Is Dispensable for β-Arrestin Recruitment
  72. Therapeutic Drug Monitoring of Tyrosine Kinase Inhibitors Using Dried Blood Microsamples
  73. Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238
  74. Monitoring the use of alcohol—A critical overview of the state‐of‐the‐art biomarkers
  75. Current evolutions, applications, and challenges of phosphatidylethanol analysis for clinical and forensic purposes
  76. Cov2MS: an automated matrix-independent assay for mass spectrometric detection and measurement of SARS-CoV-2 nucleocapsid protein in infectious patients
  77. A novel panel of yeast assays for the assessment of thiamin and its biosynthetic intermediates in plant tissues
  78. Characterization of recent non-fentanyl synthetic opioids via three different in vitro µ-opioid receptor activation assays
  79. Set‐up of a population‐based model to verify alcohol abstinence via monitoring of the direct alcohol marker phosphatidylethanol 16:0/18:1
  80. In vitro assays for the functional characterization of (psychedelic) substances at the serotonin receptor 5‐HT 2A R
  81. Structure–activity relationships of valine, tert-leucine, and phenylalanine amino acid-derived synthetic cannabinoid receptor agonists related to ADB-BUTINACA, APP-BUTINACA, and ADB-P7AICA
  82. Volumetric absorptive microsampling as a suitable tool to monitor tyrosine kinase inhibitors
  83. In-depth evaluation of automated non-contact reflectance-based hematocrit prediction of dried blood spots
  84. Near-infrared-based hematocrit prediction of dried blood spots: An in-depth evaluation
  85. Receptor density influences ligand-induced dopamine D2L receptor homodimerization
  86. A3 adenosine receptor agonists containing dopamine Moieties for enhanced interspecies affinity
  87. Determination of paracetamol and its metabolites via LC-MS/MS in dried blood volumetric absorptive microsamples: A tool for pharmacokinetic studies
  88. Are the N ‐demethylated metabolites of U‐47700 more active than their parent compound? In vitro μ‐opioid receptor activation of N ‐desmethyl‐U‐47700 and N , N ...
  89. Sensing an Oxygen Sensor: Development and Application of Activity-Based Assays Directly Monitoring HIF Heterodimerization
  90. NNL-3: A Synthetic Intermediate or a New Class of Hydroxybenzotriazole Esters with Cannabinoid Receptor Activity?
  91. Fully Automated Dried Blood Spot Extraction coupled to Liquid Chromatography-tandem Mass Spectrometry for Therapeutic Drug Monitoring of Immunosuppressants
  92. The Rise and Fall of Isotonitazene and Brorphine: Two Recent Stars in the Synthetic Opioid Firmament
  93. Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K+ leakage
  94. Alternative Sampling Strategies in Therapeutic Drug Monitoring: Microsampling Growing Toward Maturity
  95. Volumetric absorptive microsampling (VAMS) as a reliable tool to assess thiamine status in dried blood microsamples: a comparative study
  96. Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB‐4en‐PICA, MDMB‐4en‐PINACA, ADB‐4en‐PINACA, and MMB‐4CN‐BUTINACA using a combination of binding and different CB1 receptor activation assays. Part...
  97. Volumetric Absorptive Microsampling as an Alternative Tool for Biomonitoring of Multi-Mycotoxin Exposure in Resource-Limited Areas
  98. Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB‐4en‐PICA, MDMB‐4en‐PINACA, ADB‐4en‐PINACA, and MMB‐4CN‐BUTINACA using a combination of binding and different CB 1 recepto...
  99. Metabolic engineering provides insight into the regulation of thiamin biosynthesis in plants
  100. Quantification of eight hematological tyrosine kinase inhibitors in both plasma and whole blood by a validated LC-MS/MS method
  101. Synthesis and Functional Characterization of 2-(2,5-Dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine (25H-NBF) Positional Isomers
  102. Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB‐4en‐PICA, MDMB‐4en‐PINACA, ADB‐4en‐PINACA, and MMB‐4CN‐BUTINACA using a combination of binding and different CB 1 recepto...
  103. Obituary Peter Blanckaert
  104. Phenethyl-4-ANPP: A Marginally Active Byproduct Suggesting a Switch in Illicit Fentanyl Synthesis Routes
  105. Simultaneous readout of multiple FRET pairs using photochromism
  106. Synthesis, Chemical Characterization, and μ-Opioid Receptor Activity Assessment of the Emerging Group of “Nitazene” 2-Benzylbenzimidazole Synthetic Opioids
  107. Synthesis, chemical characterization, and µ-opioid receptor activity assessment  of the emerging group of ‘nitazene’ 2-benzylbenzimidazole synthetic  opioids             
  108. The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders
  109. An optimized LC-MS/MS method as a pivotal tool to steer thiamine biofortification strategies in rice
  110. Serotonin 2A Receptor (5-HT2AR) Activation by 25H-NBOMe Positional Isomers: In Vitro Functional Evaluation and Molecular Docking
  111. Metabolic engineering of rice endosperm towards higher vitamin B1 accumulation
  112. Quantitation of phosphatidylethanol in dried blood after volumetric absorptive microsampling
  113. Alternative Sampling Devices to Collect Dried Blood Microsamples
  114. Patient-Centric Assessment of Thiamine Status in Dried Blood Volumetric Absorptive Microsamples Using LC–MS/MS Analysis
  115. Simultaneous readout of multiple FRET pairs using photochromism
  116. Shape matters: The application of activity‐based in vitro bioassays and chiral profiling to the pharmacological evaluation of synthetic cannabinoid receptor agonists in drug‐infused papers seized in prisons
  117. Understanding the pharmacokinetics of synthetic cathinones: Evaluation of the blood–brain barrier permeability of 13 related compounds in rats
  118. Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of β-arrestin 2 and miniGαq bioassays
  119. Recent developments in electrochemical detection of illicit drugs in diverse matrices
  120. Synthesis and in Vitro Cannabinoid Receptor 1 Activity of Recently Detected Synthetic Cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL-CBMICA, ADB-BINACA, APP-BINACA, 4F-MDMB-BINACA, MDMB-4en-PINACA, A-CHMINACA, 5F-AB-P7AICA, 5F-MDMB-P7AICA,...
  121. Diagnosing intake and rationalizing toxicities associated with 5F-MDMB-PINACA and 4F-MDMB-BINACA abuse
  122. Cov-MS: a community-based template assay for clinical MS-based protein detection in SARS-CoV-2 patients
  123. Synthesis, chemical characterization, and µ-opioid receptor activity assessment of the emerging group of nitazene new synthetic opioids
  124. Self-sampling at home using volumetric absorptive microsampling: coupling analytical evaluation to volunteers’ perception in the context of a large scale study
  125. The next generation of synthetic cannabinoids: Detection, activity, and potential toxicity of pent‐4en and but‐3en analogues including MDMB‐4en‐PINACA
  126. Hematocrit prediction in volumetric absorptive microsamples
  127. A novel nanobody-based bio-assay using functional complementation of a split nanoluciferase to monitor Mu- opioid receptor activation
  128. Dried blood microsample-assisted determination of vitamins: recent developments and challenges
  129. Correction to: In vitro structure–activity relationship determination of 30 psychedelic new psychoactive substances by means of β-arrestin 2 recruitment to the serotonin 2A receptor
  130. First Report on Brorphine: The Next Opioid on the Deadly New Psychoactive Substance Horizon?
  131. In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances
  132. In vitro structure–activity relationship determination of 30 psychedelic new psychoactive substances by means of β-arrestin 2 recruitment to the serotonin 2A receptor
  133. In vitro activity profiling of Cumyl‐PEGACLONE variants at the CB 1 receptor: Fluorination versus isomer exploration
  134. Barriers and opportunities for the clinical implementation of therapeutic drug monitoring in oncology
  135. Report on a new opioid NPS: chemical and in vitro functional characterization of a structural isomer of the MT-45 derivative diphenpipenol
  136. Dried Blood Microsampling-Based Therapeutic Drug Monitoring of Antiepileptic Drugs in Children With Nodding Syndrome and Epilepsy in Uganda and the Democratic Republic of the Congo
  137. Toxicokinetics and toxicodynamics of the fentanyl homologs cyclopropanoyl-1-benzyl-4´-fluoro-4-anilinopiperidine and furanoyl-1-benzyl-4-anilinopiperidine
  138. Semiquantitative Activity-Based Detection of JWH-018, a Synthetic Cannabinoid Receptor Agonist, in Oral Fluid after Vaping
  139. Striatal Dopamine D2-Muscarinic Acetylcholine M1 Receptor–Receptor Interaction in a Model of Movement Disorders
  140. Assessment of structure-activity relationships and biased agonism at the Mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform
  141. Assessment of biased agonism at the A3 adenosine receptor using β-arrestin and miniGαi recruitment assays
  142. The First Comprehensive LC–MS/MS Method Allowing Dissection of the Thiamine Pathway in Plants
  143. Dried blood microsamples: suitable as an alternative matrix for the quantification of paracetamol-protein adducts?
  144. Development, validation and application of an inductively coupled plasma – mass spectrometry method to determine cobalt in metal-on-metal prosthesis patients using volumetric absorptive microsampling
  145. Report on a novel emerging class of highly potent benzimidazole NPS opioids: Chemical and in vitro functional characterization of isotonitazene
  146. Comment on HbA 1c determination from HemaSpot blood collection devices: comparison of home‐prepared dried blood spots with standard venous blood analysis
  147. Kainic acid-induced status epilepticus decreases mGlu5 receptor and phase-specifically downregulates Homer1b/c expression
  148. Setup of a Serotonin 2A Receptor (5-HT2AR) Bioassay: Demonstration of Its Applicability To Functionally Characterize Hallucinogenic New Psychoactive Substances and an Explanation Why 5-HT2AR Bioassays Are Not Suited for Universal Activity-Based Screeni...
  149. Assessment of Biased Agonism among Distinct Synthetic Cannabinoid Receptor Agonist Scaffolds
  150. Evaluation of the Performance and Hematocrit Independence of the HemaPEN as a Volumetric Dried Blood Spot Collection Device
  151. EASL Clinical Practice Guideline: Occupational liver diseases
  152. Hide and Seek: Overcoming the Masking Effect of Opioid Antagonists in Activity-Based Screening Tests
  153. Fully automated therapeutic drug monitoring of anti-epileptic drugs making use of dried blood spots
  154. Editorial: Advances in Analytical Methods for Drugs of Abuse Testing
  155. Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D2 Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor
  156. Insights into biased signaling at cannabinoid receptors: synthetic cannabinoid receptor agonists
  157. Official International Association for Therapeutic Drug Monitoring and Clinical Toxicology Guideline: Development and Validation of Dried Blood Spot–Based Methods for Therapeutic Drug Monitoring
  158. Comprehensive investigation on synthetic cannabinoids: Metabolic behavior and potency testing, using 5F‐APP‐PICA and AMB‐FUBINACA as model compounds
  159. Evidence of enzyme-mediated transesterification of synthetic cannabinoids with ethanol: potential toxicological impact
  160. Functional evaluation of carboxy metabolites of synthetic cannabinoid receptor agonists featuring scaffolds based on L‐valine or L‐ tert ‐leucine
  161. Luminescence- and Fluorescence-Based Complementation Assays to Screen for GPCR Oligomerization: Current State of the Art
  162. Enantiospecific Synthesis, Chiral Separation, and Biological Activity of Four Indazole-3-Carboxamide-Type Synthetic Cannabinoid Receptor Agonists and Their Detection in Seized Drug Samples
  163. Evaluating the applicability of mouse SINEs as an alternative normalization approach for RT-qPCR in brain tissue of the APP23 model for Alzheimer’s disease
  164. Distinct Dopamine D2 Receptor Antagonists Differentially Impact D2 Receptor Oligomerization
  165. Activity-based reporter assays for the screening of abused substances in biological matrices
  166. Clinical determination of folates: recent analytical strategies and challenges
  167. The validation of Short Interspersed Nuclear Elements (SINEs) as a RT-qPCR normalization strategy in a rodent model for temporal lobe epilepsy
  168. Is the hematocrit still an issue in quantitative dried blood spot analysis?
  169. Validation of Activity-Based Screening for Synthetic Cannabinoid Receptor Agonists in a Large Set of Serum Samples
  170. Wet absorptive microsampling at home for HbA1c monitoring in diabetic children
  171. Application of an activity‐based receptor bioassay to investigate the in vitro activity of selected indole‐ and indazole‐3‐carboxamide‐based synthetic cannabinoids at CB1 and CB2 receptors
  172. Quantification of Cocaine and Cocaine Metabolites in Dried Blood Spots from a Controlled Administration Study Using LC-MS/MS
  173. Volumetric absorptive microsampling as an alternative sampling strategy for the determination of paracetamol in blood and cerebrospinal fluid
  174. Determination of Cocaine and Metabolites in Dried Blood Spots by LC-MS/MS
  175. Probing Structure-Activity Relationship in β-Arrestin2 Recruitment of Diversely Substituted Adenosine Derivatives
  176. Evaluation of the Capitainer-B Microfluidic Device as a New Hematocrit-Independent Alternative for Dried Blood Spot Collection
  177. Synthesis toward Bivalent Ligands for the Dopamine D2 and Metabotropic Glutamate 5 Receptors
  178. Activity-Based Concept to Screen Biological Matrices for Opiates and (Synthetic) Opioids
  179. Activity-Based Detection and Bioanalytical Confirmation of a Fatal Carfentanil Intoxication
  180. Design, Synthesis, and Biological Evaluation of Bivalent Ligands Targeting Dopamine D2 -Like Receptors and the μ-Opioid Receptor
  181. Activity-Based Detection of Cannabinoids in Serum and Plasma Samples
  182. Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review
  183. Correction to: Volumetric absorptive microsampling as an alternative tool for therapeutic drug monitoring of first-generation anti-epileptic drugs
  184. Molecular dissection of the human A 3 adenosine receptor coupling with β-arrestin2
  185. Volumetric absorptive microsampling as an alternative tool for therapeutic drug monitoring of first-generation anti-epileptic drugs
  186. Correction for the Hematocrit Bias in Dried Blood Spot Analysis Using a Nondestructive, Single-Wavelength Reflectance-Based Hematocrit Prediction Method
  187. Folate Biofortification of Potato by Tuber-Specific Expression of Four Folate Biosynthesis Genes
  188. Assessing GPCR Dimerization in Living Cells: Comparison of the NanoBiT Assay with Related Bioluminescence- and Fluorescence-Based Approaches
  189. Dried blood spots in therapeutic drug monitoring and toxicology
  190. Dihydrofolate Reductase/Thymidylate Synthase Fine-Tunes the Folate Status and Controls Redox Homeostasis in Plants
  191. Activity-Based Detection of Consumption of Synthetic Cannabinoids in Authentic Urine Samples Using a Stable Cannabinoid Reporter System
  192. Alternative sampling strategies for the assessment of biomarkers of exposure
  193. The (non)sense of routinely analysing beta-hydroxybutyric acid in forensic toxicology casework
  194. Folates in Plants: Research Advances and Progress in Crop Biofortification
  195. Biomarkers in patients admitted to the emergency department after exposure to acrylonitrile in a major railway incident involving bulk chemical material
  196. Analytical confirmation of synthetic cannabinoids in a cohort of 179 presentations with acute recreational drug toxicity to an Emergency Department in London, UK in the first half of 2015
  197. Volumetric absorptive microsampling at home as an alternative tool for the monitoring of HbA1c in diabetes patients
  198. Dried blood spot analysis of gabapentin as a valid alternative for serum: a bridging study
  199. Detection and Activity Profiling of Synthetic Cannabinoids and Their Metabolites with a Newly Developed Bioassay
  200. Opening the toolbox of alternative sampling strategies in clinical routine: A key-role for (LC-)MS/MS
  201. Alternative sampling strategies for the assessment of alcohol intake of living persons
  202. Microwave-assisted on-spot derivatization for gas chromatography–mass spectrometry based determination of polar low molecular weight compounds in dried blood spots
  203. Quantification of EtG in hair, EtG and EtS in urine and PEth species in capillary dried blood spots to assess the alcohol consumption in driver’s licence regranting cases
  204. Short-term health effects in the general population following a major train accident with acrylonitrile in Belgium
  205. A Novel, Nondestructive, Dried Blood Spot-Based Hematocrit Prediction Method Using Noncontact Diffuse Reflectance Spectroscopy
  206. Degradation and interconversion of plant pteridines during sample preparation and ultra-high performance liquid chromatography–tandem mass spectrometry
  207. Alternative Sampling Strategies for Therapeutic Drug Monitoring
  208. Consumer Acceptance and Willingness-to-Pay for Genetically Modified Foods with Enhanced Vitamin Levels
  209. Disulfiram inhibition of cyanide formation after acetonitrile poisoning
  210. Quantification of phosphatidylethanol 16:0/18:1, 18:1/18:1, and 16:0/16:0 in venous blood and venous and capillary dried blood spots from patients in alcohol withdrawal and control volunteers
  211. Determination of Five Folate Monoglutamates in Rodent Diets
  212. An optimized and validated SPE-LC–MS/MS method for the determination of caffeine and paraxanthine in hair
  213. Improving folate (vitamin B9) stability in biofortified rice through metabolic engineering
  214. DBS and beyond
  215. Are capillary DBS applicable for therapeutic drug monitoring of common antipsychotics? A proof of concept
  216. DBS and beyond
  217. Alternative Sampling Strategies for Cytochrome P450 Phenotyping
  218. A validated ultra-high-performance liquid chromatography–tandem mass spectrometry method for the selective analysis of free and total folate in plasma and red blood cells
  219. Does volumetric absorptive microsampling eliminate the hematocrit bias for caffeine and paraxanthine in dried blood samples? A comparative study
  220. Role of therapeutic drug monitoring in pulmonary infections: use and potential for expanded use of dried blood spot samples
  221. Folates from metabolically engineered rice: A long-term study in rats
  222. Paraxanthine/Caffeine Concentration Ratios in Hair: An Alternative for Plasma-Based Phenotyping of Cytochrome P450 1A2?
  223. Do capillary dried blood spot concentrations of gamma-hydroxybutyric acid mirror those in venous blood? A comparative study
  224. Acrylonitrile exposure assessment in the emergency responders of a major train accident in Belgium: A human biomonitoring study
  225. Acrylonitrile exposure in the general population following a major train accident in Belgium: A human biomonitoring study
  226. CYP1A2 phenotyping in dried blood spots and microvolumes of whole blood and plasma
  227. Potassium-based algorithm allows correction for the hematocrit bias in quantitative analysis of caffeine and its major metabolite in dried blood spots
  228. Spot them in the spot: analysis of abused substances using dried blood spots
  229. Antipsychotics in dried blood spots
  230. Why Dried Blood Spots Are an Ideal Tool for CYP1A2 Phenotyping
  231. Current strategies for coping with the hematocrit problem in dried blood spot analysis
  232. Derivatization Techniques in Dried Blood Spot Analysis
  233. Folate Profiling in Potato (Solanum tuberosum) Tubers by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry
  234. Screening and confirmation methods for GHB determination in biological fluids
  235. Letter to the Editor
  236. Enhancing pterin and para-aminobenzoate content is not sufficient to successfully biofortify potato tubers and Arabidopsis thaliana plants with folate
  237. Hemato-critical issues in quantitative analysis of dried blood spots: challenges and solutions
  238. Rice folate enhancement through metabolic engineering has an impact on rice seed metabolism, but does not affect the expression of the endogenous folate biosynthesis genes
  239. Determination of gamma-hydroxybutyric acid in biofluids using a one-step procedure with “in-vial” derivatization and headspace-trap gas chromatography–mass spectrometry
  240. Feasibility of Following up Gamma-Hydroxybutyric Acid Concentrations in Sodium Oxybate (Xyrem®)-Treated Narcoleptic Patients Using Dried Blood Spot Sampling at Home
  241. Biofortified Rice to Fight Folate Deficiency
  242. Prediction of the Hematocrit of Dried Blood Spots via Potassium Measurement on a Routine Clinical Chemistry Analyzer
  243. Fatality following a suicidal overdose with varenicline
  244. Isolation and characterisation of an antifolate insensitive (afi1) mutant ofArabidopsis thaliana
  245. Inhibition of p-Aminobenzoate and Folate Syntheses in Plants and Apicomplexan Parasites by Natural Product Rubreserine
  246. Interaction of α-Catulin with Dystrobrevin Contributes to Integrity of Dystrophin Complex in Muscle
  247. Dried blood spots in toxicology: from the cradle to the grave?
  248. A folate independent role for cytosolic HPPK/DHPS upon stress in Arabidopsis thaliana
  249. Dried blood spot punches for confirmation of suspected γ-hydroxybutyric acid intoxications: validation of an optimized GC–MS procedure
  250. Quantitative liquid chromatographic analysis of anthracyclines in biological fluids
  251. The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells
  252. Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct “on spot” derivatization
  253. Mice in Ecstasy: Advanced Animal Models in the Study of MDMA
  254. Post-Mortem (Re)Distribution of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”): Human and Animal Data
  255. A field study on 8 pharmaceuticals and 1 pesticide in Belgium: Removal rates in waste water treatment plants and occurrence in surface water
  256. P-cadherin in adhesion and invasion: Opposite roles in colon and bladder carcinoma
  257. The Transcriptional Repressor Kaiso Localizes at the Mitotic Spindle and Is a Constituent of the Pericentriolar Material
  258. Ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) for the sensitive determination of folates in rice
  259. Development and validation of a liquid chromatographic method for the simultaneous determination of four anthracyclines and their respective 13-S-dihydro metabolites in plasma and saliva
  260. Optimisation and validation of a liquid chromatography–tandem mass spectrometry method for folates in rice
  261. Optimization of a liquid chromatographic separation for the simultaneous determination of four anthracyclines and their respective 13-S-dihydro metabolites
  262. E-Cadherin Regulates Human Nanos1, which Interacts with p120ctn and Induces Tumor Cell Migration and Invasion
  263. Human Immunodeficiency Virus Nef Induces Rapid Internalization of the T-Cell Coreceptor CD8αβ
  264. P-Cadherin Promotes Cell-Cell Adhesion and Counteracts Invasion in Human Melanoma
  265. Human Immunodeficiency Virus Nef Induces Rapid Internalization of the T-Cell Coreceptor CD8αβ
  266. The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation Program
  267. Roles for neuregulins in human cancer
  268. Bowes melanoma cells secrete heregulin, which can promote aggregation and counteract invasion of human mammary cancer cells
  269. P-Cadherin Is Up-Regulated by the Antiestrogen ICI 182,780 and Promotes Invasion of Human Breast Cancer Cells
  270. Melanoma cells secrete follistatin, an antagonist of activin-mediated growth inhibition
  271. Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development
  272. The Heregulin/Human Epidermal Growth Factor Receptor as a New Growth Factor System in Melanoma with Multiple Ways of Deregulation
  273. Synthesis, characterization and in vitro anti-invasive activity screening of polyphenolic and heterocyclic compounds
  274. Plasmin Produces an E-Cadherin Fragment That Stimulates Cancer Cell Invasion
  275. The Citrus Methoxyflavone Tangeretin Affects Human Cell-Cell Interactions
  276. 8-Prenylnaringenin, the phytoestrogen in hops and beer, upregulates the function of the E-cadherin/catenin complex in human mammary carcinoma cells