All Stories

  1. Baseline characteristics of patients recruited to the mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH) trial

    Article • Clinical Neurology and Neurosurgery, May 2026, Elsevier

    Prof Christine C Roffe

  2. Thrombolysis With Tenecteplase for Minor Disabling Stroke

    Article • JAMA Neurology, October 2025, American Medical Association (AMA)

    Dr Mena Farag, Prof Christine C Roffe

  3. Mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH): protocol for a prospective, randomised, open-label, blinded-endpoint phase IIb trial

    Article • BMJ Open, July 2025, BMJ

    Prof Christine C Roffe

  4. Association of Smoking and Young Cryptogenic Ischemic Stroke

    Article • Neurology Open Access, March 2025, Wolters Kluwer Health

    Professor Catarina Fonseca, Prof Christine C Roffe

  5. Cerebrovascular Pressure Restoration Rates during Recanalisation with Aspiration and Stent-Retriever Thrombectomy for Acute Ischaemic Stroke: An in Vitro Study

    Article • Journal of Neuroendovascular Therapy, January 2025, The Japanese Society for Neuroendovascular Therapy

    Prof Christine C Roffe

  6. Preventing Embolization to a New Vascular Territory: An in Vitro Study Exploring Alternative Techniques for Dual-Stent-Retriever Cerebral Thrombectomy

    Article • Journal of Neuroendovascular Therapy, January 2025, The Japanese Society for Neuroendovascular Therapy

    Prof Christine C Roffe

  7. Pre‐hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT‐2 trial

    Article • European Journal of Neurology, October 2024, Wiley

    Prof Christine C Roffe

  8. Reperfusion treatment in basilar artery occlusion presenting with mild symptoms

    Article • European Stroke Journal, August 2024, SAGE Publications

    Prof Christine C Roffe

  9. Outcome 1 year after ICH: Data from the Tranexamic acid for IntraCerebral Haemorrhage 2 (TICH-2) trial

    Article • European Stroke Journal, July 2024, SAGE Publications

    Prof Christine C Roffe

  10. Department of Error

    Article • The Lancet, June 2024, Elsevier

    Prof Christine C Roffe

  11. The Effect of Tranexamic Acid on Neurosurgical Intervention in Spontaneous Intracerebral Hematoma: Data From 121 Surgically Treated Participants From the Tranexamic Acid in IntraCerebral Hemorrhage-2 Randomized Controlled Trial

    Article • Neurosurgery, May 2024, Wolters Kluwer Health

    Prof Christine C Roffe

  12. Adult-onset mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS): a diagnostic challenge

    Article • BMJ Case Reports, February 2024, BMJ

    Prof Christine C Roffe

  13. Evaluating methods of detecting and determining the type of urinary incontinence in adults after stroke: A systematic review

    Article • Neurourology and Urodynamics, December 2023, Wiley

    Prof Christine C Roffe

  14. Is intraprocedural intravenous aspirin safe for patients who require emergent extracranial stenting during mechanical thrombectomy?

    Article • Stroke and Vascular Neurology, October 2023, BMJ

    Prof Christine C Roffe

  15. Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials

    Article • Frontiers in Stroke, September 2023, Frontiers

    Prof Christine C Roffe

  16. The effect of distal aspiration catheter position on collateral flow in mechanical thrombectomy – an in vitro study

    Article • Interventional Neuroradiology, September 2023, SAGE Publications

    Prof Christine C Roffe

  17. Reperfusion by endovascular thrombectomy and early cerebral edema in anterior circulation stroke: Results from the SITS-International Stroke Thrombectomy Registry

    Article • International Journal of Stroke, June 2023, SAGE Publications

    Prof Christine C Roffe

  18. Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial

    Article • Stroke and Vascular Neurology, June 2023, BMJ

    Prof Christine C Roffe

  19. Effects of blood pressure and tranexamic acid in spontaneous intracerebral haemorrhage: a secondary analysis of a large randomised controlled trial

    Article • BMJ Neurology Open, June 2023, BMJ

    Prof Christine C Roffe

  20. World Federation for Interventional Stroke Treatment (WIST) multispecialty training guidelines for endovascular stroke intervention

    Article • Advances in Interventional Cardiology, January 2023, Termedia Sp. z.o.o.

    Prof Christine C Roffe

  21. Association of cholesterol levels with hemorrhagic transformation and cerebral edema after reperfusion therapies

    Article • European Stroke Journal, December 2022, SAGE Publications

    Prof Christine C Roffe

  22. Systematic voiding programme in adults with urinary incontinence following acute stroke: the ICONS-II RCT

    Article • Health Technology Assessment, July 2022, National Institute for Health Research

    Prof Christine C Roffe

  23. Research priorities to improve stroke outcomes

    Article • The Lancet Neurology, April 2022, Elsevier

    Prof Christine C Roffe

  24. Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial

    Article • BMC Emergency Medicine, January 2022, Springer Science + Business Media

    Professor Aloysius Niroshan Siriwardena, Prof Christine C Roffe

  25. Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study

    Article • The Lancet, September 2021, Elsevier

    Prof Christine C Roffe

  26. Oxygen desaturation and adverse outcomes in acute stroke: Secondary analysis of the HeadPoST study

    Article • Clinical Neurology and Neurosurgery, August 2021, Elsevier

    Prof Christine C Roffe

  27. Use of Pulmonary Computed Tomography for Evaluating Suspected Stroke-Associated Pneumonia

    Article • Journal of Stroke and Cerebrovascular Diseases, June 2021, Elsevier

    Prof Christine C Roffe

  28. Purines for Rapid Identification of Stroke Mimics (PRISM): study protocol for a diagnostic accuracy study

    Article • Diagnostic and Prognostic Research, May 2021, Springer Science + Business Media

    Prof Christine C Roffe

  29. Magnitude of blood pressure change and clinical outcomes after thrombectomy in stroke caused by large artery occlusion

    Article • European Journal of Neurology, March 2021, Wiley

    Prof Christine C Roffe

  30. Outcomes in Antiplatelet‐Associated Intracerebral Hemorrhage in the TICH‐2 Randomized Controlled Trial

    Article • Journal of the American Heart Association, March 2021, Wolters Kluwer Health

    Prof Christine C Roffe

  31. The use of hypnotherapy as treatment for functional stroke: A case series from a single center in the UK

    Article • International Journal of Stroke, February 2021, SAGE Publications

    Prof Christine C Roffe

  32. Characteristics and outcomes of COVID-19 associated stroke: a UK multicentre case-control study

    Article • Journal of Neurology Neurosurgery & Psychiatry, November 2020, BMJ

    Prof Terence Quinn, Prof Christine C Roffe

  33. Assessment of fracture risk tools in care home residents: a multi-centre observational pilot study

    Article • European Geriatric Medicine, October 2020, Springer Science + Business Media

    Prof Christine C Roffe

  34. Impact of COVID-19 on stroke admissions, treatments, and outcomes at a comprehensive stroke centre in the United Kingdom

    Article • Neurological Sciences, October 2020, Springer Science + Business Media

    Prof Christine C Roffe

  35. Correction to Lancet Psychiatry 2020; 7: 875–82

    Article • The Lancet Psychiatry, October 2020, Elsevier

    Prof Christine C Roffe

  36. Mechanical thrombectomy: can it be safely delivered out of hours in the UK?

    Article • BMC Neurology, September 2020, Springer Science + Business Media

    Prof Christine C Roffe

  37. The cost of providing mechanical thrombectomy in the UK NHS: a micro-costing study

    Article • Clinical Medicine, May 2020, Elsevier

    Prof Christine C Roffe

  38. Prognostic significance of early urinary catheterization after acute stroke: Secondary analyses of the international HeadPoST trial

    Article • International Journal of Stroke, February 2020, SAGE Publications

    Craig Anderson, Prof Christine C Roffe

  39. Continuous or Intermittent? Which Regimen of Enteral Nutrition is Better for Acute Stroke Patients? a Systematic Review and Meta-Analysis

    Article • Online Journal of Neurology and Brain Disorders, November 2019, Lupine Publishers LLC

    Prof Christine C Roffe

  40. Effect of Routine Low-Dose Oxygen Supplementation on Death and Disability in Adults With Acute Stroke

    Article • JAMA, September 2017, American Medical Association (AMA)

    Prof Christine C Roffe

  41. Management of Acute Stroke in the Older Person

    Article • Geriatrics, August 2017, MDPI AG

    Prof Christine C Roffe

  42. Suction force-suction distance relation during aspiration thrombectomy for ischemic stroke: A computational fluid dynamics study

    Article • Physics in Medicine, June 2017, Elsevier

    Prof Christine C Roffe

  43. British Thoracic Society Guideline for oxygen use in adults in healthcare and emergency settings

    Article • BMJ Open Respiratory Research, May 2017, BMJ

    Prof Christine C Roffe

  44. Standards for providing safe acute ischaemic stroke thrombectomy services (September 2015)

    Article • Clinical Radiology, February 2017, Elsevier

    Prof Christine C Roffe

  45. RAPID INTERVENTION WITH GLYCERYL TRINITRATE IN HYPERTENSIVE STROKE TRIAL-2 (RIGHT-2): SAFETY AND EFFICACY OF TRANSDERMAL GLYCERYL TRINITRATE, A NITRIC OXIDE DONOR

    Article • Emergency Medicine Journal, August 2016, BMJ

    Prof Christine C Roffe

  46. Principles of practice parameters for the treatment of sleep disordered breathing in the elderly and frail elderly: the consensus of the International Geriatric Sleep Medicine Task Force

    Article • European Respiratory Journal, July 2016, European Respiratory Society (ERS)

    Prof Christine C Roffe

  47. Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, June 2016, New England Journal of Medicine (NEJM/MMS)

    Prof Christine C Roffe

  48. Validation and Recalibration of Two Multivariable Prognostic Models for Survival and Independence in Acute Stroke

    Article • PLOS One, May 2016, PLOS

    Prof Christine C Roffe

  49. Determinants and Outcomes of Stroke Following Percutaneous Coronary Intervention by Indication

    Article • Stroke, May 2016, Wolters Kluwer Health

    Prof Christine C Roffe

  50. Early Diagnosis of Pneumonia in Severe Stroke: Clinical Features and the Diagnostic Role of C-Reactive Protein

    Article • PLOS One, March 2016, PLOS

    Prof Christine C Roffe

  51. Annelies Vreeburg

    Article • BMJ, December 2015, BMJ

    Prof Christine C Roffe

  52. In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow

    Article • Journal of NeuroInterventional Surgery, August 2015, BMJ

    Prof Christine C Roffe

  53. Diagnosis of Stroke-Associated Pneumonia

    Article • Stroke, June 2015, Wolters Kluwer Health

    Dr JAVIER GARAU, Prof Christine C Roffe

  54. How Is Pneumonia Diagnosed in Clinical Stroke Research?: A Systematic Review and Meta-Analysis

    Article • Stroke, April 2015, Wolters Kluwer Health

    Prof Christine C Roffe

  55. Trends in Door-to-Thrombolysis Time in the Safe Implementation of Stroke Thrombolysis Registry: Effect of Center Volume and Duration of Registry Membership

    Article • Stroke, March 2015, Wolters Kluwer Health

    Prof Christine C Roffe

  56. Safety and Effect of Metoclopramide to Prevent Pneumonia in Patients With Stroke Fed via Nasogastric Tubes Trial

    Article • Stroke, December 2014, Wolters Kluwer Health

    Prof Christine C Roffe

  57. Geriatric Medicine: an evidence-based approach

    Article • October 2014, Oxford University Press (OUP)

    Prof Christine C Roffe

  58. Extending the role of peritoneal dialysis: can we win hearts and minds?

    Article • Nephrology Dialysis Transplantation, February 2014, Oxford University Press (OUP)

    Prof Christine C Roffe

  59. Statistical analysis plan for the Stroke Oxygen Study (SO2S): a multi-center randomized controlled trial to assess whether routine oxygen supplementation in the first 72 hours after a stroke improves long-term outcome

    Article • Trials, January 2014, Springer Science + Business Media

    Prof Christine C Roffe

  60. The Stroke Oxygen Study (SO2S) - a multi-center, study to assess whether routine oxygen treatment in the first 72 hours after a stroke improves long-term outcome: study protocol for a randomized controlled trial

    Article • Trials, January 2014, Springer Science + Business Media

    Prof Christine C Roffe

  61. Mechanical Thrombectomy for Ischaemic Stroke: The First UK Case Series

    Article • PLOS One, December 2013, PLOS

    Prof Christine C Roffe

  62. Incidence of Venous Thromboembolism in the Wake of the Clots in Legs Or sTockings after Stroke (CLOTS) Study

    Article • Stroke, August 2013, Wolters Kluwer Health

    Prof Christine C Roffe

  63. The Stroke Oxygen Pilot Study: A Randomized Controlled Trial of the Effects of Routine Oxygen Supplementation Early after Acute Stroke—Effect on Key Outcomes at Six Months

    Article • PLOS One, June 2013, PLOS

    Prof Christine C Roffe

  64. Mechanical Thrombectomy in Acute Ischaemic Stroke: A Review of the Literature, Clinical Effectiveness and Future Use

    Article • CNS & Neurological Disorders - Drug Targets, April 2013, Bentham Science Publishers

    Prof Christine C Roffe

  65. Verbessert die routinemässige Sauerstoffgabe bei akuten Hirnschlag-Patienten das Behandlungsergebnis?

    Article • Praxis, April 2013, Hogrefe Publishing Group

    Prof Christine C Roffe

  66. Coiling Occlusion of the Vertebral Artery for a Patient with Recurrent Posterior Circulation TIAs

    Article • The Neuroradiology Journal, February 2013, SAGE Publications

    Prof Christine C Roffe

  67. Does routine oxygen supplementation in patients with acute stroke improve outcome?

    Article • BMJ, November 2012, BMJ

    Prof Christine C Roffe

  68. Intermittent Nocturnal Hypoxemia in Individuals with Dementia: Prevalence and Relationship with Functional Status

    Article • Journal of the American Geriatrics Society, October 2012, Wiley

    Prof Christine C Roffe

  69. Can Surface Neuromuscular Electrical Stimulation of the Wrist and Hand Combined With Routine Therapy Facilitate Recovery of Arm Function in Patients With Stroke?

    Article • Archives of Physical Medicine and Rehabilitation, October 2012, Elsevier

    Prof Christine C Roffe

  70. Thrombolysis in a stroke patient with Marfan syndrome

    Article • JRSM Short Reports, April 2012, SAGE Publications

    Prof Christine C Roffe

  71. Sleep apnoea and stroke

    Article • Somnologie - Schlafforschung und Schlafmedizin, August 2011, Springer Science + Business Media

    Prof Christine C Roffe

  72. The SOS Pilot Study: A RCT of Routine Oxygen Supplementation Early after Acute Stroke—Effect on Recovery of Neurological Function at One Week

    Article • PLOS One, May 2011, PLOS

    Prof Christine C Roffe

  73. Comparison of the Effectiveness of Three Methods of Recanalization in a Model of the Middle Cerebral Artery: Thrombus Aspiration via a 4F Catheter, Thrombus Aspiration via the GP Thromboaspiration Device, and Mechanical Thrombectomy Using the Solitaire...

    Article • Stroke Research and Treatment, January 2011, Hindawi Publishing Corporation

    Prof Christine C Roffe

  74. SUCCESSFUL TREATMENT OF CHARLES BONNET SYNDROME WITH NOCTURNAL OXYGEN SUPPLEMENTATION

    Article • Journal of the American Geriatrics Society, November 2010, Wiley

    Prof Christine C Roffe

  75. In Vitro Testing of a New Aspiration Thrombus Device

    Article • Journal of Stroke and Cerebrovascular Diseases, March 2010, Elsevier

    Prof Christine C Roffe

  76. Frequency of nocturnal hypoxia in clinically stable patients during stroke rehabilitation

    Article • Clinical Rehabilitation, February 2010, SAGE Publications

    Prof Christine C Roffe

  77. The Role of Reality Monitoring in Anosognosia for Hemiplegia

    Article • Behavioural Neurology, January 2010, Hindawi Publishing Corporation

    Prof Christine C Roffe

  78. A Randomized Controlled Trial of the Effect of Fixed-dose Routine Nocturnal Oxygen Supplementation on Oxygen Saturation in Patients with Acute Stroke

    Article • Journal of Stroke and Cerebrovascular Diseases, January 2010, Elsevier

    Prof Christine C Roffe

  79. Computational Modeling of a New Thrombectomy Device for the Extraction of Blood Clots

    Article • January 2010, Springer Science + Business Media

    Prof Christine C Roffe

  80. Quantitative Measurement of Poststroke Spasticity and Response to Treatment With Botulinum Toxin: A 2-Patient Case Report

    Article • Physical Therapy, May 2009, Oxford University Press (OUP)

    Prof Christine C Roffe

  81. An investigation into the agreement between clinical, biomechanical and neurophysiological measures of spasticity

    Article • Clinical Rehabilitation, December 2008, SAGE Publications

    Prof Christine C Roffe

  82. Hypoxaemia and stroke

    Article • Reviews in Clinical Gerontology, November 2008, Cambridge University Press

    Prof Christine C Roffe

  83. Nutritional status after acute stroke: Is a stroke unit better than a general geriatric ward?

    Article • The journal of nutrition health & aging, May 2008, Springer Science + Business Media

    Prof Christine C Roffe

  84. Day–night Differences in Oxygen Saturation and the Frequency of Desaturations in the First 24 Hours in Patients With Acute Stroke

    Article • Journal of Stroke and Cerebrovascular Diseases, November 2007, Elsevier

    Prof Christine C Roffe

  85. Development of a Conversion Factor to Facilitate Comparison of National Institute of Health Stroke Scale Scores with Scandinavian Stroke Scale Scores

    Article • Cerebrovascular Diseases, October 2007, Karger Publishers

    Prof Christine C Roffe

  86. What Patients Want: Consumer Involvement in the Design of a Randomized Controlled Trial of Routine Oxygen Supplementation After Acute Stroke

    Article • Stroke, February 2006, Wolters Kluwer Health

    Prof Christine C Roffe

  87. Prospective, randomized, controlled, single-blind trial of the costs and consequences of systematic nutrition team follow-up over 12 mo after percutaneous endoscopic gastrostomy

    Article • Nutrition, November 2005, Elsevier

    Prof Christine C Roffe

  88. The Effect of Different Doses of Oxygen Administration on Oxygen Saturation in Patients With Stroke

    Article • Neurocritical Care, January 2005, Springer Science + Business Media

    Prof Christine C Roffe

  89. Response: Nocturnal Hypoxia After Stroke

    Article • Stroke, April 2004, Wolters Kluwer Health

    Prof Christine C Roffe

  90. Unexpected Nocturnal Hypoxia in Patients With Acute Stroke

    Article • Stroke, October 2003, Wolters Kluwer Health

    Prof Christine C Roffe

  91. Hypoxia and stroke

    Article • Age and Ageing, July 2002, Oxford University Press (OUP)

    Prof Christine C Roffe

  92. Hypoxaemia and stroke

    Article • Reviews in Clinical Gerontology, November 2001, Cambridge University Press

    Prof Christine C Roffe

  93. Effect of Hemiparetic Stroke on Pulse Oximetry Readings on the Affected Side

    Article • Stroke, August 2001, Wolters Kluwer Health

    Prof Christine C Roffe

  94. Carbaril for head lice

    Article • The Lancet, September 2000, Elsevier

    Prof Christine C Roffe

  95. Drugs in Stroke

    Article • July 2000, World Scientific Pub Co Pte Lt

    Prof Christine C Roffe

  96. Treatment of pediculosis capitis by dry combing

    Article • The Lancet, May 2000, Elsevier

    Prof Christine C Roffe

  97. The normal microflora and antibiotic-associated diarrhoea and colitis

    Article • January 1999, Springer Science + Business Media

    Prof Christine C Roffe

  98. The Effect of Magnesium Citrate in the Treatment of Leg Cramps

    Article • Age and Ageing, January 1998, Oxford University Press (OUP)

    Prof Christine C Roffe

  99. Unrecognized Depression in Elderly Hospital Inpatients

    Article • Age and Ageing, January 1998, Oxford University Press (OUP)

    Prof Christine C Roffe

  100. The Effect of Participation in a Study on Patents' Perception of Cramp Frequency

    Article • Age and Ageing, January 1998, Oxford University Press (OUP)

    Prof Christine C Roffe

  101. Randomised controlled trial of hydroquinine in muscle cramps

    Article • The Lancet, May 1997, Elsevier

    Prof Christine C Roffe

  102. The Effect of Continuous Magnesium Infusion on Infarct Size and Oedema in Acute Stroke in Mice

    Article • Age and Ageing, January 1997, Oxford University Press (OUP)

    Prof Christine C Roffe

  103. The effect of afterload and angiotensin II on proto-oncogene mRNA levels in the isolated working rat heart

    Article • Cardiovascular Research, June 1996, European Society of Cardiology

    Prof Christine C Roffe

  104. The effect of afterload and angiotensin II on proto-oncogene mRNA levels in the isolated working rat heart

    Article • Cardiovascular Research, June 1996, Oxford University Press (OUP)

    Prof Christine C Roffe

  105. Biotherapy for antibiotic-associated and other diarrhoeas

    Article • Journal of Infection, January 1996, Elsevier

    Prof Christine C Roffe

  106. Madness and care in the community: a medieval perspective

    Article • BMJ, December 1995, BMJ

    Prof Christine C Roffe

  107. Pasteurellosis in elk (Cervus elaphus): DNA fingerprinting of isolates

    Article • Veterinary Record, August 1995, BMJ

    Prof Christine C Roffe

  108. Investigation of the effects of intravenous magnesium sulphate on cardiac rhythm in acute myocardial infarction.

    Article • Heart, February 1994, BMJ

    Prof Christine C Roffe

  109. Proto-oncogene induction by pressure and angiotensin II in the isolated working rat heart

    Article • Journal of Hypertension, October 1993, Wolters Kluwer Health

    Prof Christine C Roffe

  110. Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2)

    Article • The Lancet, June 1992, Elsevier

    Prof Christine C Roffe

  111. Peripheral neuropathy as a complication of neuroleptic malignant syndrome.

    Article • Journal of Neurology Neurosurgery & Psychiatry, April 1991, BMJ

    Prof Christine C Roffe

  112. APLASTIC ANAEMIA IN SYSTEMIC LUPUS ERYTHEMATOSUS: A CELLULAR IMMUNE MECHANISM?

    Article • Rheumatology, January 1991, Oxford University Press (OUP)

    Prof Christine C Roffe

  113. Accidental self administration of xylazine in a veterinary nurse.

    Article • Postgraduate Medical Journal, March 1990, BMJ

    Prof Christine C Roffe

  114. The Stroke Oxygen Study: a multi-centre, prospective, randomised, open, blinded-endpoint study of routine oxygen treatment in the first 72 hours after a stroke

    Article • Springer Science + Business Media

    Prof Christine C Roffe

  115. The Stroke Oxygen Pilot Study: a randomised controlled pilot study of the effects of routine oxygen supplementation on functional outcome after acute stroke

    Article • Springer Science + Business Media

    Prof Christine C Roffe