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About my research

Dr. Rudolph is a world-renowned expert in bacterial DNA replication, repair and chromosome dynamics. His research focuses on DNA replication termination, how CRISPR-Cas systems connect to DNA processes, transcription-replication conflicts and how they shape bacterial chromosomes, and how antibiotics and antibiotic-like substances such as artificial sweeteners impact DNA replication. His goal is to understand how cells accurately duplicate genomes and what happens when these processes fail, with applications in antibiotic development and genomic instability diseases like cancer.

All Stories

  1. Article
    Finishing DNA replication can trigger genomic instability in normal cells
    Dr. Christian J Rudolph
  2. Article
    How saccharin disrupts bacteria and their biofilms.
    Dr. Christian J Rudolph
  3. Article
    Using BioID2 to map protein interactions in E. coli
    Dr. Christian J Rudolph
  4. Article
    How bacteria finish copying their DNA and why this matters
    Dr. Christian J Rudolph
  5. Article
    How DnaK helps control early CRISPR defence in E. coli.
    Dr. Christian J Rudolph
  6. Article
    How acesulfame-K affected drug-resistant bacteria and antibiotic activity.
    Dr. Christian J Rudolph
  7. Article
    E. coli replication forks can leave a small gap at Tus-ter barriers
    Dr. Christian J Rudolph
  8. Article
    A conserved DNA replication fork trap in E. coli
    Dr. Christian J Rudolph
  9. Article
    How extra DNA replication origins affect chromosome copying in E. coli
    Dr. Christian J Rudolph
  10. Article
    How E. coli helicases help DNA replication pass RNA polymerase
    Dr. Christian J Rudolph
  11. Article
    How prokaryotes finish copying circular chromosomes
    Dr. Christian J Rudolph
  12. Article
    Exonucleases help finish DNA replication in E. coli
    Dr. Christian J Rudolph
  13. Article
    How RecBCD protects E. coli DNA when copying and transcription collide
    Dr. Christian J Rudolph
  14. Article
    Testing extra replication origins in the E. coli chromosome
    Dr. Christian J Rudolph
  15. Article
    How RecG helps E. coli avoid extra DNA copying when replication forks meet
    Dr. Christian J Rudolph
  16. Article
    What the E. coli DNA replication fork trap may do
    Dr. Christian J Rudolph
  17. Article
    How RecG may prevent harmful DNA re-copying in E. coli
    Dr. Christian J Rudolph
  18. Article
    Origin-independent synthesis in cells lacking RecG and RNase HI
    Dr. Christian J Rudolph
  19. Article
    Moving E. coli’s replication origin exposes DNA-copying conflicts
    Dr. Christian J Rudolph
  20. Article
    How RecG’s tail helps E. coli manage DNA replication
    Dr. Christian J Rudolph
  21. Article
    How E. coli avoids harmful DNA copying when replication forks collide
    Dr. Christian J RudolphProf Conrad A Nieduszynski
  22. Article
    Why E. coli struggles without DNA topoisomerase I
    Dr. Christian J Rudolph
  23. Article
    How yeast Mph1 helps sister chromatids repair DNA damage
    Dr. Christian J Rudolph
  24. Article
    How Rep helps E. coli copy its genome efficiently
    Dr. Christian J Rudolph
  25. Article
    How RecG and DNA exonucleases prevent harmful re-replication in E. coli
    Dr. Christian J Rudolph
  26. Article
    How RecG helps E. coli avoid harmful DNA re-replication
    Dr. Christian J Rudolph
  27. Article
    Rep helps E. coli copy DNA past protein roadblocks
    Dr. Christian J Rudolph
  28. Article
    How RecG prevents harmful DNA amplification in E. coli
    Dr. Christian J Rudolph
  29. Article
    How RecG helps E. coli control DNA replication after UV damage
    Dr. Christian J Rudolph
  30. Article
    How RecFOR helps E. coli restart DNA replication after UV damage
    Dr. Christian J Rudolph
  31. Article
    How cells avoid DNA replication–transcription clashes
    Dr. Christian J Rudolph
  32. Article
    How E. coli pauses DNA replication after UV damage
    Dr. Christian J Rudolph
  33. Article
    How yeast Mph1 helps cells bypass DNA damage without extra mutations
    Dr. Christian J Rudolph
  34. Article
    How yeast MPH1 helps protect the genome from DNA damage
    Dr. Christian J Rudolph
  35. Article
    Choosing how to restart stalled DNA replication forks
    Dr. Christian J Rudolph