All Stories

  1. Challenging the Macrocycle Paradigm: Four-Arm, High-Denticity Acyclic Chelators for Radiopharmaceuticals Incorporating Actinium and Lanthanides

    Article • Inorganic Chemistry, March 2026, American Chemical Society (ACS)

    Professor Chris Orvig

  2. Evaluating a triaza-18-crown-6 picolinate chelator for [212/203Pb]Pb2+ and [212/213Bi]Bi3+ theranostics

    Article • Dalton Transactions, January 2025, Royal Society of Chemistry

    Professor Chris Orvig

  3. H3trica: Versatile Macrocyclic Chelator for [225Ac]Ac3+ and [155/161Tb]Tb3+ Theranostics

    Article • Inorganic Chemistry, July 2024, American Chemical Society (ACS)

    Professor Chris Orvig

  4. H2ampa─Versatile Chelator for [203Pb]Pb2+, [213Bi]Bi3+, and [225Ac]Ac3+

    Article • Inorganic Chemistry, June 2022, American Chemical Society (ACS)

    Professor Chris Orvig

  5. [nat/89Zr][Zr(pypa)]: Thermodynamically Stable and Kinetically Inert Binary Nonadentate Complex for Radiopharmaceutical Applications

    Article • Inorganic Chemistry, November 2021, American Chemical Society (ACS)

    Professor Chris Orvig

  6. H4HBEDpa: Octadentate Chelate after A. E. Martell

    Article • Inorganic Chemistry, August 2021, American Chemical Society (ACS)

    Professor Chris Orvig

  7. Peptide and Small Molecule Inhibitors Targeting Myeloid Cell Leukemia 1 (Mcl-1) as Novel Antitumor Agents

    Article • Current Molecular Medicine, August 2021, Bentham Science Publishers

    Professor Chris Orvig

  8. Evaluation of La(XT), a novel lanthanide compound, in an OVX rat model of osteoporosis

    Article • Bone Reports, June 2021, Elsevier

    Professor Chris Orvig

  9. Phosphonate Chelators for Medicinal Metal Ions

    Article • Inorganic Chemistry, March 2021, American Chemical Society (ACS)

    Professor Chris Orvig

  10. Recent Advances in Asialoglycoprotein Receptor and Glycyrrhetinic Acid Receptor-Mediated and/or pH-Responsive Hepatocellular Carcinoma- Targeted Drug Delivery

    Article • Current Medicinal Chemistry, March 2021, Bentham Science Publishers

    Professor Chris Orvig

  11. Chemical Promiscuity of Non-Macrocyclic Multidentate Chelating Ligands for Radiometal Ions: H4neunpa-NH2 vs H4noneunpa

    Article • Inorganic Chemistry, February 2021, American Chemical Society (ACS)

    Professor Chris Orvig

  12. Getting a lead on Pb2+-amide chelators for 203/212Pb radiopharmaceuticals

    Article • Dalton Transactions, January 2021, Royal Society of Chemistry

    Professor Chris Orvig

  13. High denticity oxinate-linear-backbone chelating ligand for diagnostic radiometal ions [111In]In3+ and [89Zr]Zr4+

    Article • Dalton Transactions, January 2021, Royal Society of Chemistry

    Professor Chris Orvig

  14. Inorganic radiopharmaceutical chemistry of oxine

    Article • Dalton Transactions, January 2021, Royal Society of Chemistry

    Professor Chris Orvig

  15. Metal ion size profoundly affects H3glyox chelate chemistry

    Article • RSC Advances, January 2021, Royal Society of Chemistry

    Professor Chris Orvig

  16. Thorium chelators for targeted alpha therapy: Rapid chelation of thorium‐226

    Article • Journal of Labelled Compounds and Radiopharmaceuticals, September 2020, Wiley

    Professor Chris Orvig

  17. Discovery of a Copper-Based Mcl-1 Inhibitor as an Effective Antitumor Agent

    Article • Journal of Medicinal Chemistry, August 2020, American Chemical Society (ACS)

    Professor Chris Orvig

  18. Rapid Thermodynamically Stable Complex Formation of [nat/111In]In3+, [nat/90Y]Y3+, and [nat/177Lu]Lu3+ with H6dappa

    Article • Inorganic Chemistry, April 2020, American Chemical Society (ACS)

    Professor Chris Orvig

  19. Chelation in One Fell Swoop: Optimizing Ligands for Smaller Radiometal Ions

    Article • Inorganic Chemistry, April 2020, American Chemical Society (ACS)

    Professor Chris Orvig

  20. 225Ac-H4py4pa for Targeted Alpha Therapy

    Article • Bioconjugate Chemistry, March 2020, American Chemical Society (ACS)

    Professor Chris Orvig

  21. Coordination chemistry of [Y(pypa)]− and comparison immuno-PET imaging of [44Sc]Sc- and [86Y]Y-pypa-phenyl-TRC105

    Article • Dalton Transactions, January 2020, Royal Society of Chemistry

    Professor Chris Orvig

  22. tBu4octapa-alkyl-NHS for metalloradiopeptide preparation

    Article • Dalton Transactions, January 2020, Royal Society of Chemistry

    Professor Chris Orvig

  23. Evaluation of the Tetrakis(3-Hydroxy-4-Pyridinone) Ligand THPN with Zirconium(IV): Thermodynamic Solution Studies, Bifunctionalization, and in Vivo Assessment of Macromolecular 89Zr-THPN-Conjugates

    Article • Inorganic Chemistry, October 2019, American Chemical Society (ACS)

    Professor Chris Orvig

  24. Radiopharmaceuticals for diagnosis in nuclear medicine: a short review

    Article • Eclética Química, July 2019, Ecletica Quimica Journal

    Professor Chris Orvig

  25. Discovery of β-carboline copper(II) complexes as Mcl-1 inhibitor and in vitro and in vivo activity in cancer models

    Article • European Journal of Medicinal Chemistry, July 2019, Elsevier

    Professor Chris Orvig

  26. Octadentate Oxine-Armed Bispidine Ligand for Radiopharmaceutical Chemistry

    Article • Inorganic Chemistry, June 2019, American Chemical Society (ACS)

    Professor Chris Orvig

  27. In vitro and in vivo anti-tumor activity of two gold(III) complexes with isoquinoline derivatives as ligands

    Article • European Journal of Medicinal Chemistry, November 2018, Elsevier

    Professor Chris Orvig

  28. Radioactive Main Group and Rare Earth Metals for Imaging and Therapy

    Article • Chemical Reviews, October 2018, American Chemical Society (ACS)

    Professor Chris Orvig

  29. H4octox: Versatile Bimodal Octadentate Acyclic Chelating Ligand for Medicinal Inorganic Chemistry

    Article • Journal of the American Chemical Society, October 2018, American Chemical Society (ACS)

    Professor Chris Orvig

  30. H2hox: Dual-Channel Oxine-Derived Acyclic Chelating Ligand for 68Ga Radiopharmaceuticals

    Article • Inorganic Chemistry, July 2018, American Chemical Society (ACS)

    Professor Chris Orvig

  31. Multi-Target Metal-Based Anticancer Agents

    Article • Current Topics in Medicinal Chemistry, November 2017, Bentham Science Publishers

    Professor Chris Orvig

  32. Biological Imaging with Medium-Sensitive Bichromatic Flexible Fluorescent Dyes

    Article • Angewandte Chemie, November 2017, Wiley

    Professor Chris Orvig

  33. Biological Imaging with Medium-Sensitive Bichromatic Flexible Fluorescent Dyes

    Article • Angewandte Chemie, November 2017, Wiley

    Professor Chris Orvig

  34. Di- and Trivalent Metal-Ion Solution Studies with the Phosphinate-Containing Heterocycle DEDA-(PO)

    Article • Inorganic Chemistry, August 2017, American Chemical Society (ACS)

    Professor Chris Orvig

  35. A Perspective – can copper complexes be developed as a novel class of therapeutics?

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Professor Chris Orvig

  36. Frontiers in radionuclide imaging and therapy, a chemical journey from naturally radioactive elements to targeted theranostic agents

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Professor Chris Orvig

  37. H4octapa: synthesis, solution equilibria and complexes with useful radiopharmaceutical metal ions

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Professor Chris Orvig

  38. Dipicolinate Complexes of Gallium(III) and Lanthanum(III)

    Article • Inorganic Chemistry, November 2016, American Chemical Society (ACS)

    Professor Chris Orvig

  39. A comparative evaluation of the chelators H 4 octapa and CHX-A″-DTPA with the therapeutic radiometal 90 Y

    Article • Nuclear Medicine and Biology, September 2016, Elsevier

    Professor Chris Orvig

  40. Novel “bi-modal” H 2 dedpa derivatives for radio- and fluorescence imaging

    Article • Journal of Inorganic Biochemistry, September 2016, Elsevier

    Professor Chris Orvig

  41. Synthesis, characterization, and evaluation of the antimicrobial potential of copper(II) coordination complexes with quinolone and p -xylenyl-linked quinolone ligands

    Article • Journal of Inorganic Biochemistry, September 2016, Elsevier

    Professor Chris Orvig

  42. In silico to in vitro screening of hydroxypyridinones as acetylcholinesterase inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, March 2016, Elsevier

    Professor Chris Orvig

  43. Evaluation of H2CHXdedpa, H2dedpa- and H2CHXdedpa-N,N′-propyl-2-NI ligands for 64Cu(ii) radiopharmaceuticals

    Article • Dalton Transactions, January 2016, Royal Society of Chemistry

    Professor Chris Orvig

  44. Gallium(iii) and iron(iii) complexes of quinolone antimicrobials

    Article • Dalton Transactions, January 2016, Royal Society of Chemistry

    Professor Chris Orvig

  45. Harnessing the bone-seeking ability of Ca(ii)-like metal ions in the treatment of metastatic cancer and resorption disorders

    Article • Chemical Society Reviews, January 2016, Royal Society of Chemistry

    Professor Chris Orvig

  46. Synthesis and characterization of lipophilic cationic Ga(iii) complexes based on the H2CHXdedpa and H2dedpa ligands and their 67/68Ga radiolabeling studies

    Article • RSC Advances, January 2016, Royal Society of Chemistry

    Professor Chris Orvig

  47. H2CHXdedpa and H4CHXoctapa—Chiral Acyclic Chelating Ligands for 67/68Ga and 111In Radiopharmaceuticals

    Article • Inorganic Chemistry, January 2015, American Chemical Society (ACS)

    Professor Chris Orvig

  48. Ion Exchange in Hydroxyapatite with Lanthanides

    Article • Inorganic Chemistry, January 2015, American Chemical Society (ACS)

    Professor Chris Orvig

  49. In vivo study and thermodynamic investigation of two lanthanum complexes, La(dpp)3 and La(XT), for the treatment of bone resorption disorders

    Article • Chemical Science, January 2015, Royal Society of Chemistry

    Professor Chris Orvig

  50. High-denticity ligands based on picolinic acid for 111In radiochemistry

    Article • Canadian Journal of Chemistry, August 2014, Canadian Science Publishing

    Professor Chris Orvig

  51. H6phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with89Zr,111In and177Lu

    Article • Dalton Transactions, January 2014, Royal Society of Chemistry

    Professor Chris Orvig

  52. 3-Hydroxy-4-pyridinone derivatives as metal ion and amyloid binding agents

    Article • Metallomics, January 2014, Oxford University Press (OUP)

    Professor Chris Orvig

  53. Structural Characteristics of Chloroquine-Bridged Ferrocenophane Analogues of Ferroquine May Obviate Malaria Drug-Resistance Mechanisms

    Article • Journal of Medicinal Chemistry, February 2013, American Chemical Society (ACS)

    Professor Chris Orvig

  54. Werner coordination chemistry and neurodegeneration

    Article • Chemical Society Reviews, January 2013, Royal Society of Chemistry

    Professor Chris Orvig

  55. In vitro studies of lanthanide complexes for the treatment of osteoporosis

    Article • Dalton Transactions, January 2013, Royal Society of Chemistry

    Professor Chris Orvig

  56. Exploring the multifunctionality of thioflavin- and deferiprone-based molecules as acetylcholinesterase inhibitors for potential application in Alzheimer's disease

    Article • Molecular BioSystems, January 2013, Royal Society of Chemistry

    Professor Chris Orvig

  57. Synthesis and in vitro anticancer activity of ferrocenyl-aminoquinoline-carboxamide conjugates

    Article • Inorganica Chimica Acta, December 2012, Elsevier

    Professor Chris Orvig

  58. H2azapa: a Versatile Acyclic Multifunctional Chelator for 67Ga, 64Cu, 111In, and 177Lu

    Article • Inorganic Chemistry, October 2012, American Chemical Society (ACS)

    Professor Chris Orvig

  59. The art of building multifunctional metal-binding agents from basic molecular scaffolds for the potential application in neurodegenerative diseases

    Article • Coordination Chemistry Reviews, October 2012, Elsevier

    Professor Chris Orvig

  60. RGD conjugates of the H2dedpa scaffold: synthesis, labeling and imaging with 68Ga

    Article • Nuclear Medicine and Biology, August 2012, Elsevier

    Professor Chris Orvig

  61. 1,1′-Disubstituted Ferrocenyl Carbohydrate Chloroquine Conjugates as Potential Antimalarials

    Article • Organometallics, June 2012, American Chemical Society (ACS)

    Professor Chris Orvig

  62. Modular Synthesis of 1,2- and 1,1′-Disubstituted Ferrocenyl Carbohydrate Chloroquine and Mefloquine Conjugates as Potential Antimalarial Agents

    Article • Organometallics, June 2012, American Chemical Society (ACS)

    Professor Chris Orvig

  63. Evaluation of the H2dedpa Scaffold and its cRGDyK Conjugates for Labeling with 64Cu

    Article • Inorganic Chemistry, May 2012, American Chemical Society (ACS)

    Professor Chris Orvig

  64. H4octapa: An Acyclic Chelator for 111In Radiopharmaceuticals

    Article • Journal of the American Chemical Society, May 2012, American Chemical Society (ACS)

    Professor Chris Orvig

  65. 1,2-Disubstituted ferrocenyl carbohydrate chloroquine conjugates as potential antimalarial agents

    Article • Dalton Transactions, January 2012, Royal Society of Chemistry

    Professor Chris Orvig

  66. New Ga derivatives of the H2dedpa scaffold with improved clearance and persistent heart uptake

    Article • Nuclear Medicine and Biology, November 2011, Elsevier

    Professor Chris Orvig

  67. One to chelate them all: investigation of a versatile, bifunctional chelator for 64Cu, 99mTc, Re and Co

    Article • Dalton Transactions, January 2011, Royal Society of Chemistry

    Professor Chris Orvig

  68. N-Aryl-substituted 3-(β-D-glucopyranosyloxy)-2-methyl-4(1H)-pyridinones as agents for Alzheimer's therapy

    Article • Chemical Science, January 2011, Royal Society of Chemistry

    Professor Chris Orvig

  69. Biosorbents for hexavalent chromium elimination from industrial and municipal effluents

    Article • Coordination Chemistry Reviews, December 2010, Elsevier

    Professor Chris Orvig, Professor (Full) of Chemistry Bidyut Saha

  70. Acyclic Chelate with Ideal Properties for68Ga PET Imaging Agent Elaboration

    Article • Journal of the American Chemical Society, November 2010, American Chemical Society (ACS)

    Professor Chris Orvig

  71. Cationic technetium and rhenium complexes with pendant carbohydrates

    Article • Applied Radiation and Isotopes, June 2010, Elsevier

    Professor Chris Orvig

  72. Dalton Transactions: Increasing Impact

    Article • Dalton Transactions, January 2010, Royal Society of Chemistry

    Professor Chris Orvig

  73. In vitro studies of 3-hydroxy-4-pyridinones and their glycosylated derivatives as potential agents for Alzheimer's disease

    Article • Dalton Transactions, January 2010, Royal Society of Chemistry

    Professor Chris Orvig

  74. Medicinal Inorganic Chemistry Approaches to Passivation and Removal of Aberrant Metal Ions in Disease

    Article • Chemical Reviews, October 2009, American Chemical Society (ACS)

    Professor Chris Orvig

  75. Stan Kirschner—An appreciation

    Article • Coordination Chemistry Reviews, August 2009, Elsevier

    Professor Chris Orvig

  76. Design, Synthesis, and Imaging of Small Amphiphilic Rhenium and99mTechnetium Tricarbonyl Complexes

    Article • Bioconjugate Chemistry, May 2009, American Chemical Society (ACS)

    Professor Chris Orvig

  77. Calorimetric studies of the interaction between the insulin-enhancing drug candidate bis(maltolato)oxovanadium(IV) (BMOV) and human serum apo-transferrin

    Article • Journal of Inorganic Biochemistry, April 2009, Elsevier

    Professor Chris Orvig

  78. Vanadium treatment of type 2 diabetes: A view to the future

    Article • Journal of Inorganic Biochemistry, April 2009, Elsevier

    Professor Chris Orvig

  79. Long-chain rhenium and technetium glucosamine conjugates

    Article • Dalton Transactions, January 2009, Royal Society of Chemistry

    Professor Chris Orvig

  80. Glucosamine conjugates bearing N,N,O-donors: potential imaging agents utilizing the [M(CO)3]+ core (M = Re, Tc)

    Article • Dalton Transactions, January 2009, Royal Society of Chemistry

    Professor Chris Orvig

  81. Cytotoxicity of the traditional chinese medicine (TCM) plumbagin in its copper chemistry

    Article • Dalton Transactions, January 2009, Royal Society of Chemistry

    Professor Chris Orvig

  82. Divalent later transition metal complexes of the traditional chinese medicine (TCM) liriodenine: coordination chemistry, cytotoxicity and DNA binding studies

    Article • Dalton Transactions, January 2009, Royal Society of Chemistry

    Professor Chris Orvig

  83. Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies

    Article • Dalton Transactions, January 2009, Royal Society of Chemistry

    Professor Chris Orvig

  84. Glycosylated tetrahydrosalens as multifunctional molecules for Alzheimer's therapy

    Article • Dalton Transactions, January 2009, Royal Society of Chemistry

    Professor Chris Orvig

  85. 2008: a record year for Dalton Transactions!

    Article • Dalton Transactions, January 2009, Royal Society of Chemistry

    Professor Chris Orvig

  86. Molecular Architectures for Trimetallic d/f/d Complexes: Magnetic Studies of a LnCu2Core

    Article • Inorganic Chemistry, April 2008, American Chemical Society (ACS)

    Professor Chris Orvig

  87. Molecular Architectures for Trimetallic d/f/d Complexes: Structural and Magnetic Properties of a LnNi2Core

    Article • Inorganic Chemistry, April 2008, American Chemical Society (ACS)

    Professor Chris Orvig

  88. Theoretical Studies of the Tautomers of Pyridinethiones

    Article • The Journal of Physical Chemistry A, April 2008, American Chemical Society (ACS)

    Professor Chris Orvig

  89. Pyridine−tert-Nitrogen−Phenol Ligands: N,N,O-Type Tripodal Chelates for the [M(CO)3]+Core (M = Re, Tc)

    Article • Inorganic Chemistry, February 2008, American Chemical Society (ACS)

    Professor Chris Orvig

  90. Dalton Transactions: providing the best services

    Article • Dalton Transactions, January 2008, Royal Society of Chemistry

    Professor Chris Orvig

  91. 99m-Technetium carbohydrate conjugates as potential agents in molecular imaging

    Article • Chemical Communications, January 2008, Royal Society of Chemistry

    Professor Chris Orvig

  92. Altering pyridinone N-substituents to optimise activity as potential prodrugs for Alzheimer's disease

    Article • Dalton Transactions, January 2008, Royal Society of Chemistry

    Professor Chris Orvig

  93. 55Cobalt complexes with pendant carbohydrates as potential PET imaging agents

    Article • Applied Radiation and Isotopes, December 2007, Elsevier

    Professor Chris Orvig

  94. Synthesis, Characterization, and Metal Coordinating Ability of Multifunctional Carbohydrate-Containing Compounds for Alzheimer's Therapy

    Article • Journal of the American Chemical Society, June 2007, American Chemical Society (ACS)

    Professor Chris Orvig

  95. Combating Alzheimer's Disease With Multifunctional Molecules Designed for Metal Passivation

    Article • Angewandte Chemie, February 2007, Wiley

    Professor Chris Orvig

  96. Lanthanide containing compounds for therapeutic care in bone resorption disorders

    Article • Dalton Transactions, January 2007, Royal Society of Chemistry

    Professor Chris Orvig

  97. Vanadium in diabetes: 100 years from Phase 0 to Phase I

    Article • Journal of Inorganic Biochemistry, December 2006, Elsevier

    Professor Chris Orvig

  98. Synthesis, Structure, and Biological Activity of Ferrocenyl Carbohydrate Conjugates

    Article • Inorganic Chemistry, October 2006, American Chemical Society (ACS)

    Professor Chris Orvig

  99. Carbohydrate-Appended 3-Hydroxy-4-pyridinone Complexes of the [M(CO)3]+Core (M = Re,99mTc,186Re)

    Article • Bioconjugate Chemistry, September 2006, American Chemical Society (ACS)

    Professor Chris Orvig

  100. Glucosamine Conjugates of Tricarbonylcyclopentadienyl Rhenium(I) and Technetium(I) Cores

    Article • Inorganic Chemistry, August 2006, American Chemical Society (ACS)

    Professor Chris Orvig

  101. Lanthanide(iii) and group 13 metal ion complexes of tripodal amino phosphinate ligands

    Article • Dalton Transactions, January 2006, Royal Society of Chemistry

    Professor Chris Orvig

  102. Metal complexes of maltol and close analogues in medicinal inorganic chemistry

    Article • Chemical Society Reviews, January 2006, Royal Society of Chemistry

    Professor Chris Orvig

  103. Metal complexes in medicinal chemistry: new vistas and challenges in drug design

    Article • Dalton Transactions, January 2006, Royal Society of Chemistry

    Professor Chris Orvig

  104. Design of targeting ligands in medicinal inorganic chemistry

    Article • Chemical Society Reviews, January 2006, Royal Society of Chemistry

    Professor Chris Orvig

  105. Editorial: Lanthanide compounds for therapeutic and diagnostic applications

    Article • Chemical Society Reviews, January 2006, Royal Society of Chemistry

    Professor Chris Orvig

  106. Carbohydrate-Bearing 3-Hydroxy-4-pyridinonato Complexes of Gallium(III) and Indium(III)

    Article • Bioconjugate Chemistry, November 2005, American Chemical Society (ACS)

    Professor Chris Orvig

  107. Synthesis and characterization of dual function vanadyl, gallium and indium curcumin complexes for medicinal applications

    Article • Journal of Inorganic Biochemistry, November 2005, Elsevier

    Professor Chris Orvig

  108. Synthesis and insulin-mimetic activities of metal complexes with 3-hydroxypyridine-2-carboxylic acid

    Article • Journal of Inorganic Biochemistry, June 2005, Elsevier

    Professor Chris Orvig

  109. Carbohydrate-Appended 2,2‘-Dipicolylamine Metal Complexes as Potential Imaging Agents

    Article • Inorganic Chemistry, April 2005, American Chemical Society (ACS)

    Professor Chris Orvig

  110. Coordination Chemistry and Insulin-Enhancing Behavior of Vanadium Complexes with Maltol C6H6O3Structural Isomers

    Article • Inorganic Chemistry, April 2005, American Chemical Society (ACS)

    Professor Chris Orvig

  111. Group 13 and Lanthanide Complexes with MixedO,SAnionic Ligands Derived from Maltol

    Article • Inorganic Chemistry, April 2005, American Chemical Society (ACS)

    Professor Chris Orvig

  112. New Insights into the Interactions of Serum Proteins with Bis(maltolato)oxovanadium(IV):  Transport and Biotransformation of Insulin-Enhancing Vanadium Pharmaceuticals

    Article • Journal of the American Chemical Society, April 2005, American Chemical Society (ACS)

    Professor Chris Orvig

  113. Vanadium Complexes with MixedO,SAnionic Ligands Derived from Maltol:  Synthesis, Characterization, and Biological Studies

    Article • Inorganic Chemistry, April 2005, American Chemical Society (ACS)

    Professor Chris Orvig

  114. A glucosamine–dipicolylamine conjugate of99mTc(i) and186Re(i) for use in imaging and therapy

    Article • Dalton Transactions, January 2005, Royal Society of Chemistry

    Professor Chris Orvig

  115. Coordination chemistry of P, O-bidentate phosphinophenolates with Ga3+ and In3+

    Article • Dalton Transactions, January 2005, Royal Society of Chemistry

    Professor Chris Orvig

  116. Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone

    Article • Journal of Inorganic Biochemistry, December 2004, Elsevier

    Professor Chris Orvig

  117. Novel Carbohydrate-Appended Metal Complexes for Potential Use in Molecular Imaging

    Article • Chemistry - A European Journal, November 2004, Wiley

    Professor Chris Orvig

  118. Carbohydrate Conjugates for Molecular Imaging and Radiotherapy: 99mTc(I) and186Re(I) Tricarbonyl Complexes ofN-(2‘-Hydroxybenzyl)-2-amino-2-deoxy-d-glucose

    Article • Bioconjugate Chemistry, July 2004, American Chemical Society (ACS)

    Professor Chris Orvig

  119. Comparison of anti-hyperglycemic effect amongst vanadium, molybdenum and other metal maltol complexes

    Article • Journal of Inorganic Biochemistry, May 2004, Elsevier

    Professor Chris Orvig

  120. Synthesis and insulinomimetic activities of novel mono- and tetranuclear oxovanadium(IV) complexes with 3-hydroxypyridine-2-carboxylic acid

    Article • Journal of Inorganic Biochemistry, January 2004, Elsevier

    Professor Chris Orvig

  121. Chronic glucose-lowering effects of rosiglitazone and bis(ethylmaltolato)oxovanadium(IV) in ZDF rats

    Article • Canadian Journal of Physiology and Pharmacology, November 2003, Canadian Science Publishing

    Professor Chris Orvig

  122. Boon and Bane of Metal Ions in Medicine

    Article • Science, May 2003, American Association for the Advancement of Science

    Professor Chris Orvig

  123. dlfComplexes with Uniform Coordination Geometry:  Structural and Magnetic Properties of an LnNi2 Core Supported by a Heptadentate Amine Phenol Ligand

    Article • Inorganic Chemistry, March 2003, American Chemical Society (ACS)

    Professor Chris Orvig

  124. Preparation and characterization of vanadyl complexes with bidentate maltol-type ligands; in vivo comparisons of anti-diabetic therapeutic potential

    Article • JBIC Journal of Biological Inorganic Chemistry, January 2003, Springer Science + Business Media

    Professor Chris Orvig

  125. Vanadyl−Thiazolidinedione Combination Agents for Diabetes Therapy

    Article • Bioconjugate Chemistry, January 2003, American Chemical Society (ACS)

    Professor Chris Orvig

  126. Synthesis and solution studies of the complexes of pyrone analogue ligands with vanadium(IV) and vanadium(V)

    Article • Inorganica Chimica Acta, November 2002, Elsevier

    Professor Chris Orvig

  127. Reduction of [VO2(ma)2]-and [VO2(ema)2]-by Ascorbic Acid and Glutathione:  Kinetic Studies of Pro-Drugs for the Enhancement of Insulin Action†

    Article • Inorganic Chemistry, March 2002, American Chemical Society (ACS)

    Professor Chris Orvig

  128. Two-Dimensional (2D) Pulsed Electron Paramagnetic Resonance Study of VO2+−Triphosphate Interactions:  Evidence for Tridentate Triphosphate Coordination, and Relevance To Bone Uptake and Insulin Enhancement by Vanadium Pharmaceuticals

    Article • Journal of the American Chemical Society, March 2002, American Chemical Society (ACS)

    Professor Chris Orvig

  129. Synthesis and Solution Studies of the Complexes of Trivalent Lanthanides with the Tetraazamacrocycle TETA-(PO)2

    Article • Inorganic Chemistry, January 2002, American Chemical Society (ACS)

    Professor Chris Orvig

  130. Article • Molecular and Cellular Biochemistry, January 2002, Springer Science + Business Media

    Professor Chris Orvig

  131. Influence of Chelation and Oxidation State on Vanadium Bioavailability, and Their Effects on Tissue Concentrations of Zinc, Copper, and Iron

    Article • Biological Trace Element Research, January 2002, Springer Science + Business Media

    Professor Chris Orvig

  132. Unprecedented sugar-dependent in vivo antitumor activity of carbohydrate-pendant cis-diamminedichloroplatinum(II) complexes

    Article • Bioorganic & Medicinal Chemistry Letters, December 2001, Elsevier

    Professor Chris Orvig

  133. Coordination chemistry of vanadium in metallopharmaceutical candidate compounds

    Article • Coordination Chemistry Reviews, October 2001, Elsevier

    Professor Chris Orvig

  134. Insulin-Enhancing Vanadium(III) Complexes

    Article • Inorganic Chemistry, August 2001, American Chemical Society (ACS)

    Professor Chris Orvig

  135. [ReO(N2O2)X] Complexes:  “4 + 1”?

    Article • Inorganic Chemistry, August 2001, American Chemical Society (ACS)

    Professor Chris Orvig

  136. Lanthanide Chemistry with Bis{[bis(carboxymethyl)amino]methyl}phosphinate:  What Does an Extra Phosphinate Group Do to EDTA?

    Article • Inorganic Chemistry, July 2001, American Chemical Society (ACS)

    Professor Chris Orvig

  137. Sugar-Pendant Diamines

    Article • The Journal of Organic Chemistry, April 2001, American Chemical Society (ACS)

    Professor Chris Orvig

  138. Chemistry of Re withN,N‘-Bis(2-pyridylmethyl)ethylenediamine (H2pmen):  Hydrolysis, Dehydrogenation, and Ternary Complexes

    Article • Inorganic Chemistry, April 2001, American Chemical Society (ACS)

    Professor Chris Orvig

  139. Effects of Sequential Replacement of −NH2by −OH in the Tripodal Tetraamine Tren on Its Acidity and Metal Ion Coordinating Properties†

    Article • Inorganic Chemistry, March 2001, American Chemical Society (ACS)

    Professor Chris Orvig

  140. Proton- and lanthanide-coordinating properties of the tetraaza macrocycle (EDDA-KA)2 in aqueous solution

    Article • Canadian Journal of Chemistry, January 2001, Canadian Science Publishing

    Professor Chris Orvig

  141. Seven-Coordinate [ReVON4X2]+Complexes (X = O and Cl)†

    Article • Inorganic Chemistry, December 2000, American Chemical Society (ACS)

    Professor Chris Orvig

  142. Coaggregation of Paramagnetic d- and f-Block Metal Ions with a Podand-Framework Amine Phenol Ligand†

    Article • Inorganic Chemistry, February 2000, American Chemical Society (ACS)

    Professor Chris Orvig

  143. Homotrinuclear Lanthanide(III) Arrays:  Assembly of and Conversion from Mononuclear and Dinuclear Units†

    Article • Inorganic Chemistry, February 2000, American Chemical Society (ACS)

    Professor Chris Orvig

  144. Acid–base and metal ion-binding properties of diaminopropyl D-glucopyranoside and diaminopropyl D-mannopyranoside compounds in aqueous solution

    Article • Journal of the Chemical Society Dalton Transactions, January 2000, Royal Society of Chemistry

    Professor Parisa Mehrkhodavandi, Professor Chris Orvig

  145. Design of vanadium compounds as insulin enhancing agents

    Article • Journal of the Chemical Society Dalton Transactions, January 2000, Royal Society of Chemistry

    Professor Chris Orvig

  146. In Vivo Electron Spin−Echo Envelope Modulation (ESEEM) Spectroscopy:  First Observation of Vanadyl Coordination to Phosphate in Bone

    Article • Journal of the American Chemical Society, December 1999, American Chemical Society (ACS)

    Professor Chris Orvig

  147. Active Oxygen Species Formation in Synaptosomes Exposed to an Aluminum Chelator

    Article • Neurotoxicology and Teratology, May 1998, Elsevier

    Professor Chris Orvig

  148. Glucose-lowering properties of vanadium compounds: Comparison of coordination complexes with maltol or kojic acid as ligands

    Article • Journal of Inorganic Biochemistry, November 1997, Elsevier

    Professor Chris Orvig

  149. Selectivity among, and aggregation of, lanthanide ions

    Article • Journal of Alloys and Compounds, March 1997, Elsevier

    Professor Chris Orvig

  150. Effects of low and high dose administration of bis(maltolato)oxovanadium(IV) on fa/fa Zucker rats

    Article • Canadian Journal of Physiology and Pharmacology, January 1996, Canadian Science Publishing

    Professor Chris Orvig

  151. Highly Symmetric Group 13 Metal−Phosphinato Complexes:  Multinuclear NMR (27Al, 31P, 71Ga) Determination of Stability Constants at Low pH

    Article • Journal of the American Chemical Society, January 1996, American Chemical Society (ACS)

    Professor Chris Orvig

  152. Reaction chemistry of BMOV, bis(maltolato)oxovanadium(IV), a potent insulin mimetic agent

    Article • Journal of the American Chemical Society, December 1995, American Chemical Society (ACS)

    Professor Chris Orvig

  153. Evidence for energy-dependent transport of aluminum out of brain extracellular fluid

    Article • Toxicology, April 1995, Elsevier

    Professor Chris Orvig, Professor Robert A Yokel

  154. Increased potency of vanadium using organic ligands

    Article • Molecular and Cellular Biochemistry, January 1995, Springer Science + Business Media

    Professor Chris Orvig

  155. Pharmacokinetics of aluminum 3-hydroxypyridin-4-one complexes: implications for aluminum redistribution subsequent to chelation therapy

    Article • Toxicology, September 1994, Elsevier

    Professor Chris Orvig, Professor Robert A Yokel

  156. Bis(maltolato)oxovanadium(IV) is a potent insulin mimic

    Article • Journal of Medicinal Chemistry, April 1992, American Chemical Society (ACS)

    Professor Chris Orvig

  157. Potential 67Ga radiopharmaceuticals for myocardial imaging: Tris(1-aryl-3-hydroxy-2-methyl-4-pyridinonato)gallium(III) complexes

    Article • International Journal of Radiation Applications and Instrumentation Part B Nuclear Medicine and Biology, April 1992, Elsevier

    Professor Chris Orvig

  158. General method for the synthesis of trishydroxamic acids

    Article • Tetrahedron Letters, March 1992, Elsevier

    Professor Chris Orvig

  159. Design and synthesis of multidentate 2-(2′-hydroxyphenyl)-2-thiazolines for biomedical application

    Article • Tetrahedron, January 1992, Elsevier

    Professor Chris Orvig

  160. Structural characterization of the octachloroditechnetate(III) ion in its tetrabutylammonium salt

    Article • Inorganic Chemistry, September 1981, American Chemical Society (ACS)

    Professor Chris Orvig