All Stories

  1. MEK Guards Proteome Stability and Inhibits Tumor-Suppressive Amyloidogenesis via HSF1

    Article • Cell, February 2015, Elsevier

    Dr Chengkai Dai Dai

  2. Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK

    Article • The EMBO Journal, November 2014, EMBO

    Dr Chengkai Dai Dai

  3. Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis

    Article • Journal of Clinical Investigation, October 2012, American Society for Clinical Investigation

    Dr Chengkai Dai Dai

  4. Proteotoxic stress of cancer: Implication of the heat-shock response in oncogenesis

    Article • Journal of Cellular Physiology, April 2012, Wiley

    Dr Chengkai Dai Dai

  5. Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis

    Article • Cell, September 2007, Elsevier

    Dr Chengkai Dai Dai

  6. HSP90: a rising star on the horizon of anticancer targets

    Article • Future Oncology, August 2005, Future Medicine

    Dr Chengkai Dai Dai

  7. The Characteristics of Astrocytomas and Oligodendrogliomas Are Caused by Two Distinct and Interchangeable Signaling Formats

    Article • Neoplasia, April 2005, Elsevier

    Dr Chengkai Dai Dai

  8. Dose-Dependent Effects of Platelet-Derived Growth Factor-B on Glial Tumorigenesis

    Article • Cancer Research, July 2004, American Association for Cancer Research (AACR)

    Dr Chengkai Dai Dai

  9. Overexpression of c-MYC promotes an undifferentiated phenotype in cultured astrocytes and allows elevated Ras and Akt signaling to induce gliomas from GFAP-expressing cells in mice

    Article • Neuron Glia Biology, May 2004, Cambridge University Press

    Dr Chengkai Dai Dai

  10. Astrocyte Differentiation States and Glioma Formation

    Article • The Cancer Journal, March 2003, Wolters Kluwer Health

    Dr Chengkai Dai Dai

  11. p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human Chromosome 19q13.3

    Article • Genes & Development, February 2003, Cold Spring Harbor Laboratory Press

    Dr Chengkai Dai Dai

  12. MYC Expression Promotes the Proliferation of Neural Progenitor Cells in Culture and In Vivo

    Article • Neoplasia, January 2002, Elsevier

    Dr Chengkai Dai Dai

  13. Glioma models

    Article • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, August 2001, Elsevier

    Dr Chengkai Dai Dai

  14. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

    Article • Genes & Development, August 2001, Cold Spring Harbor Laboratory Press

    Dr Chengkai Dai Dai

  15. Astrocytes Give Rise to Oligodendrogliomas and Astrocytomas after Gene Transfer of Polyoma Virus Middle T Antigen in Vivo

    Article • American Journal Of Pathology, September 2000, Elsevier

    Dr Chengkai Dai Dai

  16. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

    Article • Nature Genetics, May 2000, Springer Science + Business Media

    Dr Chengkai Dai Dai