Professor Changquan Sun

Molecular Interpretation of Mechanical Behavior in Four Basic Crystal Packing of Isonia...

• Crystal Growth & Design
• January 2020

Microstructures and pharmaceutical properties of ferulic acid agglomerates prepared by ...

• International Journal of Pharmaceutics
• January 2020

Expedited Investigation of Powder Caking Aided by Rapid 3D Prototyping of Testing Devices

• Journal of Pharmaceutical Sciences
• January 2020

Crystallographic and Energetic Insights into Reduced Dissolution and Physical Stability...

• Molecular Pharmaceutics
• December 2019

Molecular Interpretation of the Compaction Performance and Mechanical Properties of Caf...

• Molecular Pharmaceutics
• December 2019

Improving Powder Characteristics by Surface Modification Using Atomic Layer Deposition

• Organic Process Research & Development
• November 2019

Correction to Fast Determination of Phase Stability of Hydrates Using Intrinsic Dissolu...

• Crystal Growth & Design
• November 2019

Effect of particle size on interfacial bonding strength of bilayer tablets

• Powder Technology
• November 2019

Structural Features of Sulfamethizole and Its Cocrystals: Beauty Within

• Crystal Growth & Design
• October 2019

Fast Determination of Phase Stability of Hydrates Using Intrinsic Dissolution Rate Meas...

• Crystal Growth & Design
• September 2019

Insights into the effect of compaction pressure and material properties on interfacial ...

• Powder Technology
• September 2019

Relationship between hydrate stability and accuracy of true density measured by helium ...

• International Journal of Pharmaceutics
• August 2019

Minimum Interfacial Bonding Strength for Bilayer Tablets Determined Using a Survival Test

• Pharmaceutical Research
• July 2019

Correction to Crystal Growth of Celecoxib from Amorphous State: Polymorphism, Growth Me...

• Crystal Growth & Design
• July 2019

Single-Crystal Plasticity Defies Bulk-Phase Mechanics in Isoniazid Cocrystals with Anal...

• Crystal Growth & Design
• July 2019

Tableting performance of various mannitol and lactose grades assessed by compaction sim...

• International Journal of Pharmaceutics
• July 2019

Crystal growth of celecoxib from amorphous state – polymorphism, growth mechanism, and ...

• Crystal Growth & Design
• May 2019

Reduced Punch Sticking Propensity of Acesulfame by Salt Formation: Role of Crystal Mech...

• Molecular Pharmaceutics
• April 2019

Twistable Pharmaceutical Crystal Exhibiting Exceptional Plasticity and Tabletability

• Chemistry of Materials
• April 2019

Expedited Tablet Formulation Development of a Highly Soluble Carbamazepine Cocrystal En...

• Pharmaceutical Research
• April 2019

Effect of screw profile and processing conditions on physical transformation and chemic...

• European Journal of Pharmaceutical Sciences
• April 2019

Direct Compression Tablet Containing 99% Active Ingredient—A Tale of Spherical Crystall...

• Journal of Pharmaceutical Sciences
• April 2019

Cocrystal Engineering of Itraconazole with Suberic Acid via Rotary Evaporation and Spra...

• Crystal Growth & Design
• April 2019

Computational Techniques for Predicting Mechanical Properties of Organic Crystals: A Sy...

• Molecular Pharmaceutics
• March 2019

Profoundly Improved Plasticity and Tabletability of Griseofulvin by in Situ Solvation a...

• Crystal Growth & Design
• March 2019

Spherical Cocrystallization—An Enabling Technology for the Development of High Dose Dir...

• Crystal Growth & Design
• March 2019

Effects of thermal binders on chemical stabilities and tabletability of gabapentin gran...

• International Journal of Pharmaceutics
• March 2019

Effects of Water on Powder Flowability of Diverse Powders Assessed by Complimentary Tec...

• Journal of Pharmaceutical Sciences
• March 2019

Exceptionally Elastic Single-Component Pharmaceutical Crystals

• Chemistry of Materials
• February 2019

Developing Biologics Tablets: The Effects of Compression on the Structure and Stability...

• Molecular Pharmaceutics
• February 2019

Polymer Nanocoating of Amorphous Drugs for Improving Stability, Dissolution, Powder Flo...

• Molecular Pharmaceutics
• February 2019

Robust bulk preparation and characterization of sulfamethazine and saccharine salt and ...

• CrystEngComm
• January 2019

A platform direct compression formulation for low dose sustained-release tablets enable...

• Powder Technology
• January 2019

Improving solid-state properties of berberine chloride through forming a salt cocrystal...

• International Journal of Pharmaceutics
• January 2019

Mechanism for the Reduced Dissolution of Ritonavir Tablets by Sodium Lauryl Sulfate

• Journal of Pharmaceutical Sciences
• January 2019

Proportionality between powder cohesion and unconfined yield strength from shear cell t...

• Heliyon
• January 2019

Cubosomes with surface cross-linked chitosan exhibit sustained release and bioavailabil...

• RSC Advances
• January 2019

A systematic evaluation of dual functionality of sodium lauryl sulfate as a tablet lubr...

• International Journal of Pharmaceutics
• December 2018

Mechanical Properties

• September 2018

Cocrystallization of Curcumin with Benzenediols and Benzenetriols via Rapid Solvent Rem...

• Crystal Growth & Design
• August 2018

Preparation, Characterization, and Formulation Development of Drug–Drug Protic Ionic Li...

• Molecular Pharmaceutics
• August 2018

Ribbon density and milling parameters that determine fines fraction in a dry granulation

• Powder Technology
• July 2018

Comparative analyses of flow and compaction properties of diverse mannitol and lactose ...

• International Journal of Pharmaceutics
• July 2018

Anion Exchange Reaction for Preparing Acesulfame Solid Forms

• Crystal Growth & Design
• June 2018

Relating the tableting behavior of piroxicam polytypes to their crystal structures usin...

• International Journal of Pharmaceutics
• May 2018

Systematic evaluation of common lubricants for optimal use in tablet formulation

• European Journal of Pharmaceutical Sciences
• May 2018

The relationship among tensile strength, Young's modulus, and indentation hardness of p...

• Powder Technology
• May 2018

Crystal and Particle Engineering Strategies for Improving Powder Compression and Flow P...

• April 2018

Modulating Sticking Propensity of Pharmaceuticals Through Excipient Selection in a Dire...

• Pharmaceutical Research
• March 2018

A mesoporous silica based platform to enable tablet formulations of low dose drugs by d...

• International Journal of Pharmaceutics
• March 2018

Identifying Slip Planes in Organic Polymorphs by Combined Energy Framework Calculations...

• Crystal Growth & Design
• February 2018

Reduced interface spin polarization by antiferromagnetically coupled Mn segregated to t...

• January 2018

Lack of dependence of mechanical properties of baicalein cocrystals on those of the con...

• CrystEngComm
• January 2018

Subsurface nucleation of supercooled acetaminophen

• CrystEngComm
• January 2018

Improving Dissolution Rate of Carbamazepine-Glutaric Acid Cocrystal Through Solubilizat...

• Pharmaceutical Research
• December 2017

Relationships among Crystal Structures, Mechanical Properties, and Tableting Performanc...

• Crystal Growth & Design
• October 2017

Dependence of Friability on Tablet Mechanical Properties and a Predictive Approach for ...

• Pharmaceutical Research
• October 2017

Expedited development of a high dose orally disintegrating metformin tablet enabled by ...

• International Journal of Pharmaceutics
• October 2017

The suitability of common compressibility equations for characterizing plasticity of di...

• International Journal of Pharmaceutics
• October 2017

Tablets of multi-unit pellet system for controlled drug delivery

• Journal of Controlled Release
• September 2017

Expedited Development of Diphenhydramine Orally Disintegrating Tablet through Integrate...

• Molecular Pharmaceutics
• August 2017

Ribbon thickness influences fine generation during dry granulation

• International Journal of Pharmaceutics
• August 2017

Dependence of Punch Sticking on Compaction Pressure—Roles of Particle Deformability and...

• August 2017

Particle Engineering for Enabling a Formulation Platform Suitable for Manufacturing Low...

• July 2017

Dapagliflozin-citric acid cocrystal showing better solid state properties than dapaglif...

• European Journal of Pharmaceutical Sciences
• June 2017

Superior Plasticity and Tabletability of Theophylline Monohydrate

• Molecular Pharmaceutics
• May 2017

Gaining insight into tablet capping tendency from compaction simulation

• International Journal of Pharmaceutics
• May 2017

Tensile and shear methods for measuring strength of bilayer tablets

• International Journal of Pharmaceutics
• May 2017

Powder properties and compaction parameters that influence punch sticking propensity of...

• International Journal of Pharmaceutics
• April 2017

Lubrication with magnesium stearate increases tablet brittleness

• Powder Technology
• March 2017

A top coating strategy with highly bonding polymers to enable direct tableting of multi...

• Powder Technology
• January 2017

Mechanical Properties and Tableting Behavior of Amorphous Solid Dispersions

• January 2017

Mechanism and Kinetics of Punch Sticking of Pharmaceuticals

• January 2017

Preparation of slab-shaped lactose carrier particles for dry powder inhalers by air jet...

• Asian Journal of Pharmaceutical Sciences
• January 2017

Self-templating accelerates precipitation of carbamazepine dihydrate during the dissolu...

• CrystEngComm
• January 2017

The phenomenon of tablet flashing — Its impact on tableting data analysis and a method ...

• Powder Technology
• January 2017

Harvesting Potential Dissolution Advantages of Soluble Cocrystals by Depressing Precipi...

• Crystal Growth & Design
• October 2016

Process optimization of dry granulation based tableting line: Extracting physical mater...

• Powder Technology
• October 2016

Analytical method development for powder characterization: Visualization of the critica...

• Journal of Pharmaceutical and Biomedical Analysis
• September 2016

Solid-state characterization of optically pure (+)Dihydromyricetin extracted from Ampe...

• International Journal of Pharmaceutics
• September 2016

Enhancing Bioavailability of Dihydromyricetin through Inhibiting Precipitation of Solub...

• Crystal Growth & Design
• August 2016

A classification system for tableting behaviors of binary powder mixtures

• Asian Journal of Pharmaceutical Sciences
• August 2016

Microstructure of Tablet—Pharmaceutical Significance, Assessment, and Engineering

• Pharmaceutical Research
• July 2016

Resveratrol cocrystals with enhanced solubility and tabletability

• International Journal of Pharmaceutics
• July 2016

Macroindentation hardness measurement—Modernization and applications

• International Journal of Pharmaceutics
• June 2016

Enabling the Tablet Product Development of 5-Fluorocytosine by Conjugate Acid Base Cocr...

• June 2016

Mini review: Mechanisms to the loss of tabletability by dry granulation

• European Journal of Pharmaceutics and Biopharmaceutics
• April 2016

Sweet Berberine

• Crystal Growth & Design
• February 2016

Quantifying effects of moisture content on flow properties of microcrystalline cellulos...

• Powder Technology
• February 2016

A critical Examination of the Phenomenon of Bonding Area - Bonding Strength Interplay i...

• Pharmaceutical Research
• January 2016

From molecular salt to pseudo CAB cocrystal: Expanding solid-state landscape of carboxy...

• Journal of Molecular Structure
• November 2015

The development of carbamazepine-succinic acid cocrystal tablet formulations with impro...

• Drug Development and Industrial Pharmacy
• October 2015

Dependence of tablet brittleness on tensile strength and porosity

• International Journal of Pharmaceutics
• September 2015

Tabletability Modulation Through Surface Engineering

• Journal of Pharmaceutical Sciences
• August 2015

Development of highly stabilized curcumin nanoparticles by flash nanoprecipitation and ...

• European Journal of Pharmaceutics and Biopharmaceutics
• August 2015

Dependence of ejection force on tableting speed—A compaction simulation study

• Powder Technology
• July 2015

A new tablet brittleness index

• European Journal of Pharmaceutics and Biopharmaceutics
• June 2015

Near-infrared chemical imaging (NIR-CI) as a process monitoring solution for a producti...

• European Journal of Pharmaceutics and Biopharmaceutics
• June 2015

Validation and applications of an expedited tablet friability method

• International Journal of Pharmaceutics
• April 2015

Correlation Among Crystal Structure, Mechanical Behavior, and Tabletability in the Co-C...

• Crystal Growth & Design
• April 2015

Designing Micellar Nanocarriers with Improved Drug Loading and Stability Based on Solub...

• Molecular Pharmaceutics
• March 2015

Significant Expansion of the Solid State Landscape of Salicylic Acid Based on Charge-As...

• Crystal Growth & Design
• January 2015

Solvent and additive interactions as determinants in the nucleation pathway: general di...

• Faraday Discussions
• January 2015

Nucleation in complex multi-component and multi-phase systems: general discussion

• Faraday Discussions
• January 2015

Effect of Heating Rate and Kinetic Model Selection on Activation Energy of Nonisotherma...

• Journal of Pharmaceutical Sciences
• December 2014

Kinetic Entrapment of a Hidden Curcumin Cocrystal with Phloroglucinol

• Crystal Growth & Design
• October 2014

Effect of Crystal Habit on Intrinsic Dissolution Behavior of Celecoxib Due to Different...

• Crystal Growth & Design
• October 2014

Assessment of the relative performance of a confined impinging jets mixer and a multi-i...

• European Journal of Pharmaceutics and Biopharmaceutics
• October 2014

Design and Preparation of a 4:1 Lamivudine–Oxalic Acid CAB Cocrystal for Improving the ...

• Crystal Growth & Design
• August 2014

Origin of Deteriorated Crystal Plasticity and Compaction Properties of a 1:1 Cocrystal ...

• Crystal Growth & Design
• August 2014

A Formulation Strategy for Solving the Overgranulation Problem in High Shear Wet Granul...

• Journal of Pharmaceutical Sciences
• August 2014

Enabling Tablet Product Development of 5-Fluorocytosine Through Integrated Crystal and ...

• Journal of Pharmaceutical Sciences
• April 2014

Evolution of Structure and Properties of Granules Containing Microcrystalline Cellulose...

• Journal of Pharmaceutical Sciences
• January 2014

Improving manufacturability of an ibuprofen powder blend by surface coating with silica...

• Powder Technology
• November 2013

Impact of Crystal Habit on Biopharmaceutical Performance of Celecoxib

• Crystal Growth & Design
• July 2013

Design, Synthesis, and Characterization of New 5-Fluorocytosine Salts

• Molecular Pharmaceutics
• June 2013

Enabling direct compression of formulated Danshen powder by surface engineering

• Powder Technology
• June 2013

A Pitfall in Analyzing Powder Compatibility Data Using Nonlinear Regression

• Journal of Pharmaceutical Sciences
• March 2013

Protonation of Cytosine: Cytosinium vs Hemicytosinium Duplexes

• Crystal Growth & Design
• February 2013

Synthon preference in O-protonated amide crystals – dominance of short strong hydrogen ...

• CrystEngComm
• January 2013

Improved solid-state stability of salts by cocrystallization between conjugate acid–bas...

• CrystEngComm
• January 2013

Cocrystallization for successful drug delivery

• Expert Opinion on Drug Delivery
• December 2012

Preparation and Characterization of Surface-Engineered Coarse Microcrystalline Cellulos...

• Journal of Pharmaceutical Sciences
• November 2012

Correction for Polymorphs, Salts and Cocrystals: What’s in a Name?

• Crystal Growth & Design
• August 2012

Probing Interfaces between Pharmaceutical Crystals and Polymers by Neutron Reflectometry

• Molecular Pharmaceutics
• July 2012

Polymorphs, Salts, and Cocrystals: What’s in a Name?

• Crystal Growth & Design
• May 2012

Do not confuse hydrogen chloride with hydrochloric acid!

• Chemistry - A European Journal
• April 2012

Simultaneously Improving the Mechanical Properties, Dissolution Performance, and Hygros...

• Pharmaceutical Research
• February 2012

Ionized form of acetaminophen with improved compaction properties

• CrystEngComm
• January 2012

Design and synthesis of solid state structures with conjugate acid–base pair interactions

• CrystEngComm
• January 2012

Direct correlation among crystal structure, mechanical behaviour and tabletability in a...

• CrystEngComm
• January 2012

Origin of Two Modes of Non-isothermal Crystallization of Glasses Produced by Milling

• Pharmaceutical Research
• December 2011

Profoundly improving flow properties of a cohesive cellulose powder by surface coating ...

• Journal of Pharmaceutical Sciences
• November 2011

Reproducibility of flow properties of microcrystalline cellulose — Avicel PH102

• Powder Technology
• September 2011

Initial moisture content in raw material can profoundly influence high shear wet granul...

• International Journal of Pharmaceutics
• September 2011

Overcoming Poor Tabletability of Pharmaceutical Crystals by Surface Modification

• Pharmaceutical Research
• June 2011

Massing in high shear wet granulation can simultaneously improve powder flow and deteri...

• European Journal of Pharmaceutical Sciences
• May 2011

Origin of profound changes in powder properties during wetting and nucleation stages of...

• Powder Technology
• April 2011

Understanding Size Enlargement and Hardening of Granules on Tabletability of Unlubricat...

• Journal of Pharmaceutical Sciences
• February 2011

Decoding Powder Tabletability: Roles of Particle Adhesion and Plasticity

• Journal of Adhesion Science and Technology
• January 2011

The Manufacture of Low-Dose Oral Solid Dosage Form to Support Early Clinical Studies Us...

• AAPS PharmSciTech
• December 2010

Transforming Powder Mechanical Properties by Core/Shell Structure: Compressible Sand

• Journal of Pharmaceutical Sciences
• November 2010

Roles of Granule Size in Over-Granulation During High Shear Wet Granulation

• Journal of Pharmaceutical Sciences
• August 2010

Setting the bar for powder flow properties in successful high speed tableting

• Powder Technology
• July 2010

Understanding the relationship between crystal structure, plasticity and compaction beh...

• CrystEngComm
• January 2010

Characterization of thermal behavior of deep eutectic solvents and their potential as d...

• International Journal of Pharmaceutics
• August 2009

Improving Powder Flow Properties of Citric Acid by Crystal Hydration

• Journal of Pharmaceutical Sciences
• May 2009

Materials Science Tetrahedron—A Useful Tool for Pharmaceutical Research and Development

• Journal of Pharmaceutical Sciences
• May 2009

Development of a high drug load tablet formulation based on assessment of powder manufa...

• Journal of Pharmaceutical Sciences
• January 2009

Quantifying Effects of Particulate Properties on Powder Flow Properties Using a Ring Sh...

• Journal of Pharmaceutical Sciences
• September 2008

On the Identification of Slip Planes in Organic Crystals Based on Attachment Energy Cal...

• Journal of Pharmaceutical Sciences
• August 2008

Improving Mechanical Properties of Caffeine and Methyl Gallate Crystals by Cocrystalliz...

• Crystal Growth & Design
• May 2008

Mechanism of moisture induced variations in true density and compaction properties of m...

• International Journal of Pharmaceutics
• January 2008

On the mechanism of reduced tabletability of granules prepared by roller compaction

• International Journal of Pharmaceutics
• January 2008

Influence of crystal structure on the tableting properties of n‐alkyl 4‐hydroxybenzoate...

• Journal of Pharmaceutical Sciences
• December 2007

Thermal Expansion of Organic Crystals and Precision of Calculated Crystal Density: A Su...

• Journal of Pharmaceutical Sciences
• May 2007

Insensitivity of Compaction Properties of Brittle Granules to Size Enlargement by Rolle...

• Journal of Pharmaceutical Sciences
• May 2007

A material-sparing method for simultaneous determination of true density and powder com...

• International Journal of Pharmaceutics
• December 2006

Solid-state properties and crystallization behavior of PHA-739521 polymorphs

• International Journal of Pharmaceutics
• August 2006

Reduced tabletability of roller compacted granules as a result of granule size enlargement

• Journal of Pharmaceutical Sciences
• January 2006

True Density of Microcrystalline Cellulose

• Journal of Pharmaceutical Sciences
• October 2005

A Study of Sulfamerazine Single Crystals Using Atomic Force Microscopy, Transmission Li...

• Journal of Pharmaceutical Sciences
• September 2005

Quantifying Errors in Tableting Data Analysis Using the Ryshkewitch Equation Due to Ina...

• Journal of Pharmaceutical Sciences
• September 2005

Evaluation of the effects of tableting speed on the relationships between compaction pr...

• Journal of Pharmaceutical Sciences
• March 2005

A Novel Method for Deriving True Density of Pharmaceutical Solids Including Hydrates an...

• Journal of Pharmaceutical Sciences
• March 2004

Improved Tableting Properties of p-Hydroxybenzoic Acid by Water of Crystallization: A M...

• Pharmaceutical Research
• February 2004

Theophylline monohydrate

• Acta Crystallographica Section E Structure Reports Online
• March 2002

Influence of Crystal Shape on the Tableting Performance of L‐Lysine Monohydrochloride D...

• Journal of Pharmaceutical Sciences
• May 2001

Influence of crystal shape on the tableting performance of L‐lysine monohydrochloride d...

• Journal of Pharmaceutical Sciences
• May 2001

Influence of crystal shape on the tableting performance of L-lysine monohydrochloride d...

• Journal of Pharmaceutical Sciences
• May 2001

Effects of initial particle size on the tableting properties of l-lysine monohydrochlor...

• International Journal of Pharmaceutics
• March 2001

Influence of Elastic Deformation of Particles on Heckel Analysis

• Pharmaceutical Development and Technology
• January 2001

• January 2001

• January 2001