All Stories

  1. FSHR activation through small molecule modulators: Mechanistic insights from MD simulations

    Article • Computers in Biology and Medicine, March 2023, Elsevier

    Chandan Kumar

  2. N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Chandan Kumar

  3. Expanding the therapeutic options for Candida infections using novel inhibitors of secreted aspartyl proteases

    Article • Drug Development Research, November 2022, Wiley

    Chandan Kumar

  4. Human surfactant protein D facilitates SARS-CoV-2 pseudotype binding and entry in DC-SIGN expressing cells, and downregulates spike protein induced inflammation

    Article • Frontiers in Immunology, July 2022, Frontiers

    Professor Nigel James Temperton, Chandan Kumar

  5. Mapping of FSHR agonists and antagonists binding sites to identify potential peptidomimetic modulators

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, April 2022, Elsevier

    Chandan Kumar

  6. Computational investigation of FDA approved drugs as selective PARP-1 inhibitors by targeting BRCT domain for cancer therapy

    Article • Journal of Molecular Graphics and Modelling, November 2021, Elsevier

    Chandan Kumar

  7. Design, synthesis and biological evaluation of 2-(3,4-dimethoxyphenyl)-6 (1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridine analogues as antiproliferative agents

    Article • Bioorganic & Medicinal Chemistry Letters, September 2019, Elsevier

    Chandan Kumar

  8. A mechanistic approach to understand the allosteric reverse signaling by selective and trapping poly(ADP-ribose) polymerase 1 (PARP-1) inhibitors

    Article • Journal of Biomolecular Structure and Dynamics, June 2019, Taylor & Francis

    Chandan Kumar

  9. Structure based pharmacophore study to identify possible natural selective PARP-1 trapper as anti-cancer agent

    Article • Computational Biology and Chemistry, June 2019, Elsevier

    Chandan Kumar

  10. Computational studies on G-quadruplex DNA-stabilizing property of novel Wittig-based Schiff-Base ligands and their copper(II) complexes

    Article • Structural Chemistry, November 2018, Springer Science + Business Media

    Chandan Kumar

  11. Rutin as a potential inhibitor to target peptidoglycan pathway of Staphylococcus aureus cell wall synthesis

    Article • Clinical Microbiology and Infectious Diseases, January 2018, Open Access Text Pvt, Ltd.

    Chandan Kumar

  12. A comprehensive look of poly(ADP-ribose) polymerase inhibition strategies and future directions for cancer therapy

    Article • Future Medicinal Chemistry, January 2017, Future Science

    Chandan Kumar

  13. Dynamics of replication proteins during lagging strand synthesis: A crossroads for genomic instability and cancer

    Article • DNA Repair, June 2016, Elsevier

    Chandan Kumar

  14. Synthetic modified pyrrolo[1,4] benzodiazepine molecules demonstrate selective anticancer activity by targeting the human ligase 1 enzyme: An in silico and in vitro mechanistic study

    Article • Chemico-Biological Interactions, July 2015, Elsevier

    Chandan Kumar