All Stories

  1. APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats

    Article • Proceedings of the National Academy of Sciences, January 2025, Proceedings of the National Academy of Sciences

    Professor Catherine H. Freudenreich

  2. RNA processing prevents transcription-replication conflicts, DNA breaks, and CAG repeat contractions

    Article • PLoS Biology, December 2022, PLOS

    Professor Catherine H. Freudenreich, Rebecca Brown, Xiaofeng Su

  3. Restarted replication forks are error-prone and cause CAG repeat expansions and contractions

    Article • PLoS Genetics, October 2021, PLOS

    Professor Catherine H. Freudenreich, Rebecca Brown