All Stories

  1. Combined therapy with Benznidazole and repurposed drugs Clofazimine and Benidipine for chronic Chagas disease
  2. Quantitative structure–activity relationship models for compounds with anticonvulsant activity
  3. In Silico Modeling of FDA-Approved Drugs for Discovery of Therapies Against Neglected Diseases: A Drug Repurposing Approach
  4. Application of Machine Learning Approaches to Identify New Anticonvulsant Compounds Active in the 6 Hz Seizure Model
  5. Modern Approaches for the Discovery of Anti-Infectious Drugs for the Treatment of Neglected Diseases
  6. Drug Excretion
  7. Drug Absorption
  8. Drug Distribution
  9. Drug Metabolism
  10. Drug Transporters
  11. The Challenge of Finding New Therapies for Sleeping Sickness
  12. The application of molecular topology for ulcerative colitis drug discovery
  13. Novel cruzipain inhibitors for the chemotherapy of chronic Chagas disease
  14. Computer-guided drug repurposing: Identification of trypanocidal activity of clofazimine, benidipine and saquinavir
  15. Identification of Levothyroxine Antichagasic Activity through Computer-Aided Drug Repurposing
  16. Application of Computer-Aided Drug Repurposing in the Search of New Cruzipain Inhibitors: Discovery of Amiodarone and Bromocriptine Inhibitory Effects
  17. CNS Drug Development – Lost in Translation?
  18. An Integrated Drug Development Approach Applying Topological Descriptors
  19. Synthesis of 2-Hydrazolyl-4-Thiazolidinones Based on Multicomponent Reactions and Biological Evaluation Against Trypanosoma Cruzi
  20. Prediction of drug intestinal absorption by new linear and non-linear QSPR
  21. A successful virtual screening application: prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben
  22. Application of descriptors based on Lipinski’s rules in the QSPR study of aqueous solubilities