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  1. The Candesartan Adjunctive Depression Trials—CADET

    Article • Journal of Clinical Psychopharmacology, March 2026, Wolters Kluwer Health

    Dr Brisa Fernandes

  2. Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer’s disease

    Article • June 2024, Cold Spring Harbor Laboratory Press

    Dr Brisa Fernandes

  3. Genetic overlap between Alzheimer’s disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence

    Article • Molecular Psychiatry, March 2024, Springer Science + Business Media

    Dr Brisa Fernandes

  4. Genetic overlap between Alzheimer's disease and immune-mediated diseases: An atlas of shared genetic determinants and biological convergence

    Article • September 2023, Springer Science + Business Media

    Dr Brisa Fernandes

  5. GRPa-PRS: A risk stratification method to identify genetically-regulated pathways in polygenic diseases

    Article • June 2023, Cold Spring Harbor Laboratory Press

    Dr Brisa Fernandes

  6. Improving drug development in precision psychiatry by ameliorating cognitive biases

    Article • European Neuropsychopharmacology, May 2023, Elsevier

    Dr Brisa Fernandes

  7. The kynurenine pathway in Alzheimer's disease: a meta-analysis of central and peripheral levels

    Article • Brazilian Journal of Psychiatry, January 2023, FRACTAL EDITORA LTDA

    Dr Brisa Fernandes

  8. The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a systematic review and meta-analysis of cerebrospinal fluid studies

    Article • Brazilian Journal of Psychiatry, January 2023, FRACTAL EDITORA LTDA

    Dr Brisa Fernandes

  9. A single-cell atlas of the human brain in Alzheimer’s disease and its implications for personalized drug repositioning

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Dr Brisa Fernandes

  10. Fostering precision psychiatry through bioinformatics

    Article • Brazilian Journal of Psychiatry, April 2022, FRACTAL EDITORA LTDA

    Dr Brisa Fernandes

  11. Treatment-resistant bipolar depression: concepts and challenges for novel interventions

    Article • Brazilian Journal of Psychiatry, April 2022, FRACTAL EDITORA LTDA

    Dr Brisa Fernandes

  12. The Greater Houston Area Bipolar Registry—Clinical and Neurobiological Trajectories of Children and Adolescents With Bipolar Disorders and High-Risk Unaffected Offspring

    Article • Frontiers in Psychiatry, June 2021, Frontiers

    Dr Brisa Fernandes

  13. C-Reactive Protein and the Uncinate Fasciculus in Anhedonia and Depression

    Article • Biological Psychiatry, May 2021, Elsevier

    Dr Brisa Fernandes

  14. Lower Reward Responsiveness is Associated With Lifetime Suicide Attempt in Children and Adolescents With Bipolar Disorders

    Article • Biological Psychiatry, May 2021, Elsevier

    Dr Brisa Fernandes

  15. The Kynurenine Pathway in Major Depressive Disorder, Bipolar Disorder, and Schizophrenia: A Large Meta-Analysis

    Article • Biological Psychiatry, May 2021, Elsevier

    Dr Brisa Fernandes

  16. The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies

    Article • Molecular Psychiatry, November 2020, Springer Science + Business Media

    Dr Brisa Fernandes

  17. P.757 Antidepressant treatment decreases IL-6, IL-10 and serum cortisol in major depressive disorder: a meta-analysis of randomized controlled trials

    Article • European Neuropsychopharmacology, November 2020, Elsevier

    Dr Brisa Fernandes

  18. Precision psychiatry with immunological and cognitive biomarkers: a multi-domain prediction for the diagnosis of bipolar disorder or schizophrenia using machine learning

    Article • Translational Psychiatry, May 2020, Springer Science + Business Media

    Dr Brisa Fernandes

  19. Evidence-based umbrella review of 162 peripheral biomarkers for major mental disorders

    Article • Translational Psychiatry, May 2020, Springer Science + Business Media

    Dr Brisa Fernandes

  20. Editorial: Back to the Future: On the Road Towards Precision Psychiatry

    Article • Frontiers in Psychiatry, February 2020, Frontiers

    Dr Brisa Fernandes

  21. Mindfulness-based stress reduction for fibromyalgia: A step closer to precision psychiatry?

    Article • Brain Behavior and Immunity, October 2019, Elsevier

    Dr Brisa Fernandes

  22. Are remitted affective disorders and familial risk of affective disorders associated with metabolic syndrome, inflammation and oxidative stress? – a monozygotic twin study

    Article • Psychological Medicine, September 2019, Cambridge University Press

    Dr Brisa Fernandes

  23. Applying biomarkers in psychiatry: Paving the way towards precision psychiatry

    Article • Psychoneuroendocrinology, September 2019, Elsevier

    Dr Brisa Fernandes

  24. Innate Immune Cells and C-Reactive Protein in Acute First-Episode Psychosis and Schizophrenia: Relationship to Psychopathology and Treatment

    Article • Schizophrenia Bulletin, August 2019, Oxford University Press (OUP)

    Dr Brisa Fernandes

  25. Guidelines for the standardized collection of blood-based biomarkers in psychiatry: Steps for laboratory validity – a consensus of the Biomarkers Task Force from the WFSBP

    Article • The World Journal of Biological Psychiatry, March 2019, Taylor & Francis

    Dr Edna Grünblatt, Dr Brisa Fernandes, Kamyar Keramatian

  26. P.4.08 Metabolic syndrome, inflammation and oxidative stress as potential risk factors for affective disorders – a twin study

    Article • European Neuropsychopharmacology, January 2019, Elsevier

    Dr Brisa Fernandes

  27. Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies

    Article • Journal of Psychiatric Research, August 2018, Elsevier

    Dr Brisa Fernandes

  28. Treatment of neurocognitive symptoms in unipolar depression: A systematic review and future perspectives

    Article • Journal of Affective Disorders, October 2017, Elsevier

    Dr Brisa Fernandes

  29. The renin–angiotensin system: a possible new target for depression

    Article • BMC Medicine, August 2017, Springer Science + Business Media

    Dr Brisa Fernandes

  30. Blockade of the angiotensin system improves mental health domain of quality of life: A meta-analysis of randomized clinical trials

    Article • Australian & New Zealand Journal of Psychiatry, July 2017, SAGE Publications

    Dr Brisa Fernandes

  31. The effect of N-acetylcysteine (NAC) on human cognition – A systematic review

    Article • Neuroscience & Biobehavioral Reviews, July 2017, Elsevier

    Dr Brisa Fernandes

  32. Relationship between depression and frailty in older adults: A systematic review and meta-analysis

    Article • Ageing Research Reviews, July 2017, Elsevier

    Dr Brisa Fernandes

  33. Peripheral Alterations in Cytokine and Chemokine Levels After Antidepressant Drug Treatment for Major Depressive Disorder: Systematic Review and Meta-Analysis

    Article • Molecular Neurobiology, June 2017, Springer Science + Business Media

    Dr Brisa Fernandes

  34. Staging in bipolar disorder: one step closer to precision psychiatry

    Article • Brazilian Journal of Psychiatry, June 2017, FapUNIFESP (SciELO)

    Dr Brisa Fernandes

  35. Homocysteine as a peripheral biomarker in bipolar disorder: A meta-analysis

    Article • European Psychiatry, June 2017, Elsevier

    Dr Brisa Fernandes

  36. 338. Enabling Precision Psychiatry through ‘omics’: From Biomarkers to Biological Pathways

    Article • Biological Psychiatry, May 2017, Elsevier

    Dr Brisa Fernandes

  37. 980. Insulin is a State Biomarker in Major Depressive Disorder: A Systematic Review and Meta-Analysis

    Article • Biological Psychiatry, May 2017, Elsevier

    Dr Brisa Fernandes

  38. Oxidative stress and frailty: A systematic review and synthesis of the best evidence

    Article • Maturitas, May 2017, Elsevier

    Dr Brisa Fernandes

  39. The new field of ‘precision psychiatry’

    Article • BMC Medicine, April 2017, Springer Science + Business Media

    Dr Brisa Fernandes

  40. The Placebo and Nocebo Phenomena: Their Clinical Management and Impact on Treatment Outcomes

    Article • Clinical Therapeutics, March 2017, Elsevier

    Dr Brisa Fernandes

  41. Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies

    Article • Acta Psychiatrica Scandinavica, January 2017, Wiley

    Dr Brisa Fernandes

  42. Depression in cancer: The many biobehavioral pathways driving tumor progression

    Article • Cancer Treatment Reviews, January 2017, Elsevier

    Dr Brisa Fernandes

  43. C-reactive protein concentrations across the mood spectrum in bipolar disorder: a systematic review and meta-analysis

    Article • The Lancet Psychiatry, December 2016, Elsevier

    Dr Brisa Fernandes

  44. Affective temperaments and emotional traits are associated with a positive screening for premenstrual dysphoric disorder

    Article • Comprehensive Psychiatry, November 2016, Elsevier

    Dr Brisa Fernandes

  45. Statins for the treatment of depression: A meta-analysis of randomized, double-blind, placebo-controlled trials

    Article • Journal of Affective Disorders, August 2016, Elsevier

    Dr Brisa Fernandes

  46. Angiotensin Converting Enzyme Inhibitors and Risk of Mood Disorders

    Article • Psychotherapy and Psychosomatics, May 2016, Karger Publishers

    Dr Brisa Fernandes

  47. Bias in emerging biomarkers for bipolar disorder

    Article • Psychological Medicine, May 2016, Cambridge University Press

    Dr Brisa Fernandes

  48. T helper 17 cells may drive neuroprogression in major depressive disorder: Proposal of an integrative model

    Article • Neuroscience & Biobehavioral Reviews, May 2016, Elsevier

    Dr Brisa Fernandes, George Anderson

  49. Leptin in bipolar disorder: A systematic review and meta-analysis

    Article • European Psychiatry, May 2016, Elsevier

    Dr Brisa Fernandes

  50. N-Acetylcysteine in Depressive Symptoms and Functionality

    Article • The Journal of Clinical Psychiatry, April 2016, Physicians Postgraduate Press, Inc

    Dr Brisa Fernandes

  51. Cognitive remission: a novel objective for the treatment of major depression?

    Article • BMC Medicine, January 2016, Springer Science + Business Media

    Dr Brisa Fernandes

  52. Premenstrual Symptoms Screening Tool--Brazilian Portuguese Version

    Article • January 2016, American Psychological Association (APA)

    Dr Brisa Fernandes

  53. Bias in Peripheral Depression Biomarkers

    Article • Psychotherapy and Psychosomatics, January 2016, Karger Publishers

    Dr Brisa Fernandes

  54. Peripheral vascular endothelial growth factor as a novel depression biomarker: A meta-analysis

    Article • Psychoneuroendocrinology, December 2015, Elsevier

    Dr Brisa Fernandes

  55. Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker in bipolar disorder: a meta-analysis of 52 studies

    Article • BMC Medicine, November 2015, Springer Science + Business Media

    Dr Brisa Fernandes

  56. Effects of Depression and Serotonergic Antidepressants on Bone: Mechanisms and Implications for the Treatment of Depression

    Article • Drugs & Aging, November 2015, Springer Science + Business Media

    Dr Brisa Fernandes

  57. Future Directions for Pharmacotherapies for Treatment-resistant Bipolar Disorder

    Article • Current Neuropharmacology, October 2015, Bentham Science Publishers

    Dr Brisa Fernandes

  58. C-reactive protein is increased in schizophrenia but is not altered by antipsychotics: meta-analysis and implications

    Article • Molecular Psychiatry, July 2015, Springer Science + Business Media

    Dr Brisa Fernandes

  59. Serum triglycerides, but not cholesterol or leptin, are decreased in suicide attempters with mood disorders

    Article • Journal of Affective Disorders, February 2015, Elsevier

    Dr Brisa Fernandes

  60. Peripheral brain-derived neurotrophic factor in schizophrenia and the role of antipsychotics: meta-analysis and implications

    Article • Molecular Psychiatry, September 2014, Springer Science + Business Media

    Dr Brisa Fernandes

  61. Decreased peripheral brain-derived neurotrophic factor levels are a biomarker of disease activity in major psychiatric disorders: a comparative meta-analysis

    Article • Molecular Psychiatry, December 2013, Springer Science + Business Media

    Dr Brisa Fernandes

  62. The impact of methylphenidate on seizure frequency and severity in children with attention-deficit-hyperactivity disorder and difficult-to-treat epilepsies

    Article • Developmental Medicine & Child Neurology, March 2013, Wiley

    Dr Brisa Fernandes

  63. Biomarkers in bipolar disorder: A positional paper from the International Society for Bipolar Disorders Biomarkers Task Force

    Article • Australian & New Zealand Journal of Psychiatry, February 2013, SAGE Publications

    Dr Brisa Fernandes

  64. Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial

    Article • BMC Medicine, August 2012, Springer Science + Business Media

    Dr Brisa Fernandes

  65. Minimum 2-year follow up of sex reassignment surgery in Brazilian male-to-female transsexuals

    Article • Psychiatry and Clinical Neurosciences, May 2012, Wiley

    Dr Brisa Fernandes

  66. Reduced serum non-enzymatic antioxidant defense and increased lipid peroxidation in schizophrenic patients on a hypocaloric diet

    Article • Neuroscience Letters, March 2012, Elsevier

    Dr Brisa Fernandes

  67. The efficacy of N-acetylcysteine as an adjunctive treatment in bipolar depression: An open label trial

    Article • Journal of Affective Disorders, December 2011, Elsevier

    Dr Brisa Fernandes

  68. Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance

    Article • Brazilian Journal of Psychiatry, September 2011, FapUNIFESP (SciELO)

    Dr Brisa Fernandes

  69. Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance

    Article • Brazilian Journal of Psychiatry, September 2011, FapUNIFESP (SciELO)

    Dr Brisa Fernandes

  70. Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis

    Article • Journal of Psychiatric Research, August 2011, Elsevier

    Dr Brisa Fernandes

  71. Hypersalivation Associated with Olanzapine and Valproate Combination: A Case Report

    Article • CNS Spectrums, March 2011, Cambridge University Press

    Dr Brisa Fernandes

  72. Improvement of schizophrenia with electroconvulsive therapy and serum brain-derived neurotrophic factor levels: Lack of association in a pilot study

    Article • Psychiatry and Clinical Neurosciences, November 2010, Wiley

    Dr Brisa Fernandes

  73. Increased neurotrophin-3 in drug-free subjects with bipolar disorder during manic and depressive episodes

    Article • Journal of Psychiatric Research, July 2010, Elsevier

    Dr Brisa Fernandes

  74. Validity of the Portuguese version of the Bipolar Depression Rating Scale

    Article • Acta Neuropsychiatrica, April 2010, Cambridge University Press

    Dr Brisa Fernandes, PEDRO MAGALHAES

  75. Lack of Association Between Serum Brain-Derived Neurotrophic Factor Levels and Improvement of Schizophrenia Symptoms in a Double-Blind, Randomized, Placebo-Controlled Trial of Memantine as Adjunctive Therapy to Clozapine

    Article • The Journal of Clinical Psychiatry, January 2010, Physicians Postgraduate Press, Inc

    Dr Brisa Fernandes

  76. The concept of staging in bipolar disorder: the role of BDNF and TNF-alpha as biomarkers

    Article • Acta Neuropsychiatrica, December 2009, Cambridge University Press

    Dr Brisa Fernandes

  77. Improvement of Negative and Positive Symptoms in Treatment-Refractory Schizophrenia

    Article • The Journal of Clinical Psychiatry, October 2009, Physicians Postgraduate Press, Inc

    Dr Brisa Fernandes

  78. Serum brain-derived neurotrophic factor in bipolar and unipolar depression: A potential adjunctive tool for differential diagnosis

    Article • Journal of Psychiatric Research, October 2009, Elsevier

    Dr Brisa Fernandes

  79. Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients

    Article • Journal of Psychiatric Research, September 2009, Elsevier

    Dr Brisa Fernandes

  80. Comparison of cytokine levels in depressed, manic and euthymic patients with bipolar disorder

    Article • Journal of Affective Disorders, August 2009, Elsevier

    Dr Brisa Fernandes

  81. Serum brain-derived neurotrophic factor (BDNF) is not associated with response to electroconvulsive therapy (ECT): A pilot study in drug resistant depressed patients

    Article • Neuroscience Letters, April 2009, Elsevier

    Dr Brisa Fernandes

  82. Feasibility of Treating Swine Manure in an Anaerobic Sequencing Batch Biofilm Reactor With Mechanical Stirring

    Article • Applied Biochemistry and Biotechnology, January 2005, Springer Science + Business Media

    Dr Brisa Fernandes

  83. Evaluation of the treadmill stress testing for risk stratification after acute myocardial infarction

    Article • Arquivos Brasileiros de Cardiologia, December 1999, FapUNIFESP (SciELO)

    Dr Brisa Fernandes